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Items: 1 to 50 of 225

1.

Novel mutations in KMT2B offer pathophysiological insights into childhood-onset progressive dystonia.

Dafsari HS, Sprute R, Wunderlich G, Daimagüler HS, Karaca E, Contreras A, Becker K, Schulze-Rhonhof M, Kiening K, Karakulak T, Kloss M, Horn A, Pauls A, Nürnberg P, Altmüller J, Thiele H, Assmann B, Koy A, Cirak S.

J Hum Genet. 2019 Jun 5. doi: 10.1038/s10038-019-0625-1. [Epub ahead of print]

PMID:
31165786
2.

Dual-time-point 64 Cu-PSMA-617-PET/CT in patients suffering from prostate cancer.

Hoberück S, Wunderlich G, Michler E, Hölscher T, Walther M, Seppelt D, Platzek I, Zöphel K, Kotzerke J.

J Labelled Comp Radiopharm. 2019 May 1. doi: 10.1002/jlcr.3745. [Epub ahead of print]

PMID:
31042811
3.

Pharmacokinetics of Single Doses of BI 425809 in Healthy Chinese and Japanese Subjects: A Randomized Study.

Tsuda Y, Ugai H, Wunderlich G, Shin JG.

Clin Ther. 2019 May;41(5):961-971. doi: 10.1016/j.clinthera.2019.03.014. Epub 2019 Apr 17.

PMID:
31005336
4.
5.

A novel third-generation TSH receptor antibody (TRAb) enzyme-linked immunosorbent assay based on a murine monoclonal TSH receptor-binding antibody.

Roggenbuck JJ, Veiczi M, Conrad K, Schierack P, Wunderlich G, Kotzerke J, Roggenbuck D, Zöphel K.

Immunol Res. 2018 Dec;66(6):768-776. doi: 10.1007/s12026-018-9062-z.

PMID:
30684216
6.

Nano-multilamellar lipid vesicles (NMVs) enhance protective antibody responses against Shiga toxin (Stx2a) produced by enterohemorrhagic Escherichia coli strains (EHEC).

Rodrigues-Jesus MJ, Fotoran WL, Cardoso RM, Araki K, Wunderlich G, Ferreira LCS.

Braz J Microbiol. 2019 Jan;50(1):67-77. doi: 10.1007/s42770-018-0035-0. Epub 2018 Dec 6.

PMID:
30637647
7.

Different Radionuclides in DOTA-EB-TATE Effect Different Uptake in Somatostatin Receptor-Positive HEK293 Cells.

Kotzerke J, Runge R, Braune A, Wunderlich G.

J Nucl Med. 2019 Mar;60(3):436. doi: 10.2967/jnumed.118.220707. Epub 2018 Nov 15. No abstract available.

PMID:
30442758
8.

Evaluation of Pharmacokinetics and Pharmacodynamics of BI 425809, a Novel GlyT1 Inhibitor: Translational Studies.

Rosenbrock H, Desch M, Kleiner O, Dorner-Ciossek C, Schmid B, Keller S, Schlecker C, Moschetti V, Goetz S, Liesenfeld KH, Fillon G, Giovannini R, Ramael S, Wunderlich G, Wind S.

Clin Transl Sci. 2018 Nov;11(6):616-623. doi: 10.1111/cts.12578. Epub 2018 Aug 23.

9.

Long term history of a congenital core-rod myopathy with compound heterozygous mutations in the Nebulin gene.

Wunderlich G, Brunn A, Daimagüler HS, Bozoglu T, Fink GR, Lehmann HC, Weis J, Cirak S.

Acta Myol. 2018 Jun 1;37(2):121-127. eCollection 2018 Jun.

10.

Late onset necrotizing autoimmune myopathy 1 year after cessation of statin treatment.

Balke M, Brunn A, Claeys KG, Fink GR, Wunderlich G.

Acta Neurol Belg. 2018 Jul 14. doi: 10.1007/s13760-018-0985-x. [Epub ahead of print] No abstract available.

PMID:
30008064
11.

[Congenital myasthenic syndromes in adulthood : Challenging, rare but treatable].

Wunderlich G, Abicht A, Brunn A, Daimagüler HS, Schroeter M, Fink GR, Lehmann HC, Cirak S.

Nervenarzt. 2019 Feb;90(2):148-159. doi: 10.1007/s00115-018-0562-9. Review. German.

PMID:
29974128
12.

Independent regulation of Plasmodium falciparum rif gene promoters.

Araujo RBD, Silva TM, Kaiser CS, Leite GF, Alonso D, Ribolla PEM, Wunderlich G.

Sci Rep. 2018 Jun 19;8(1):9332. doi: 10.1038/s41598-018-27646-0.

13.

[Combined internal-external radiotherapy (CIERT) in a cell model].

Oehme L, Bartzsch T, Maucksch U, Freudenberg R, Wunderlich G, Kotzerke J.

Nuklearmedizin. 2018 Jun;57(3):108-116. doi: 10.3413/Nukmed-0954-17-12. Epub 2018 Jun 5. German.

PMID:
29871012
14.

Targeted sequencing with expanded gene profile enables high diagnostic yield in non-5q-spinal muscular atrophies.

Karakaya M, Storbeck M, Strathmann EA, Delle Vedove A, Hölker I, Altmueller J, Naghiyeva L, Schmitz-Steinkrüger L, Vezyroglou K, Motameny S, Alawbathani S, Thiele H, Polat AI, Okur D, Boostani R, Karimiani EG, Wunderlich G, Ardicli D, Topaloglu H, Kirschner J, Schrank B, Maroofian R, Magnusson O, Yis U, Nürnberg P, Heller R, Wirth B.

Hum Mutat. 2018 Sep;39(9):1284-1298. doi: 10.1002/humu.23560. Epub 2018 Jul 25.

PMID:
29858556
15.

Multiple Rising Doses of Oral BI 425809, a GlyT1 Inhibitor, in Young and Elderly Healthy Volunteers: A Randomised, Double-Blind, Phase I Study Investigating Safety and Pharmacokinetics.

Moschetti V, Schlecker C, Wind S, Goetz S, Schmitt H, Schultz A, Liesenfeld KH, Wunderlich G, Desch M.

Clin Drug Investig. 2018 Aug;38(8):737-750. doi: 10.1007/s40261-018-0660-2.

16.

Feasibility of CXCR4-Directed Radioligand Therapy in Advanced Diffuse Large B-Cell Lymphoma.

Lapa C, Hänscheid H, Kircher M, Schirbel A, Wunderlich G, Werner RA, Samnick S, Kotzerke J, Einsele H, Buck AK, Wester HJ, Grigoleit GU.

J Nucl Med. 2019 Jan;60(1):60-64. doi: 10.2967/jnumed.118.210997. Epub 2018 May 18.

PMID:
29777009
17.

The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers.

Moschetti V, Kim M, Sand M, Wunderlich G, Andersen G, Feifel U, Jang IJ, Timmer W, Rosenbrock H, Boland K.

Eur Neuropsychopharmacol. 2018 May;28(5):643-655. doi: 10.1016/j.euroneuro.2018.01.003. Epub 2018 Mar 19.

18.

Influence of polymorphisms in toll-like receptors (TLRs) on malaria susceptibility in low-endemic area of the Atlantic Forest, São Paulo, Brazil.

Guimarães LO, Fernandes F, Monteiro EF, Curado I, Holcman MM, Wunderlich G, Santos SE, Soler JM, Kirchgatter K.

Acta Trop. 2018 Jun;182:309-316. doi: 10.1016/j.actatropica.2018.03.011. Epub 2018 Mar 15.

PMID:
29551393
19.

Long-Time Course of Idiopathic Small Fiber Neuropathy.

Flossdorf P, Haupt WF, Brunn A, Deckert M, Fink GR, Lehmann HC, Wunderlich G.

Eur Neurol. 2018;79(3-4):161-165. doi: 10.1159/000487717. Epub 2018 Mar 8.

PMID:
29518780
20.

Publisher Correction: TLR4-Mediated Placental Pathology and Pregnancy Outcome in Experimental Malaria.

Barboza R, Lima FA, Reis AS, Murillo OJ, Peixoto EPM, Bandeira CL, Fotoran WL, Sardinha LR, Wunderlich G, Bevilacqua E, Lima MRD, Alvarez JM, Costa FTM, Gonçalves LA, Epiphanio S, Marinho CRF.

Sci Rep. 2018 Mar 6;8(1):4275. doi: 10.1038/s41598-018-21982-x.

21.

Ethanolic extract of the fungus Trichoderma stromaticum decreases inflammation and ameliorates experimental cerebral malaria in C57BL/6 mice.

Cariaco Y, Lima WR, Sousa R, Nascimento LAC, Briceño MP, Fotoran WL, Wunderlich G, Dos Santos JL, Silva NM.

Sci Rep. 2018 Jan 24;8(1):1547. doi: 10.1038/s41598-018-19840-x.

22.

Plasmodium dihydrofolate reductase is a second enzyme target for the antimalarial action of triclosan.

Bilsland E, van Vliet L, Williams K, Feltham J, Carrasco MP, Fotoran WL, Cubillos EFG, Wunderlich G, Grøtli M, Hollfelder F, Jackson V, King RD, Oliver SG.

Sci Rep. 2018 Jan 18;8(1):1038. doi: 10.1038/s41598-018-19549-x.

23.

Immunoproteomics of Plasmodium falciparum-infected red blood cell membrane fractions.

Cabral FJ, Vianna LG, Medeiros MM, Carlos BC, Martha RD, Silva NM, Silva LHPD, Stabeli RG, Wunderlich G.

Mem Inst Oswaldo Cruz. 2017 Dec;112(12):850-856. doi: 10.1590/0074-02760170041.

24.

Genetic ancestry effects on the distribution of toll-like receptors (TLRs) gene polymorphisms in a population of the Atlantic Forest, São Paulo, Brazil.

Guimarães LO, Bajay MM, Monteiro EF, Wunderlich G, Santos SE, Kirchgatter K.

Hum Immunol. 2018 Feb;79(2):101-108. doi: 10.1016/j.humimm.2017.11.007. Epub 2017 Nov 23.

PMID:
29175392
25.

Safety, Tolerability and Pharmacokinetics of Oral BI 425809, a Glycine Transporter 1 Inhibitor, in Healthy Male Volunteers: A Partially Randomised, Single-Blind, Placebo-Controlled, First-in-Human Study.

Moschetti V, Desch M, Goetz S, Liesenfeld KH, Rosenbrock H, Kammerer KP, Wunderlich G, Wind S.

Eur J Drug Metab Pharmacokinet. 2018 Apr;43(2):239-249. doi: 10.1007/s13318-017-0440-z.

26.

Heterologous expression of Homo sapiens alpha-folate receptors in E. coli by fusion with a trigger factor for enhanced solubilization.

Miranda BNM, Fotoran WL, Canduri F, Souza DHF, Wunderlich G, Carrilho E.

Protein Expr Purif. 2018 Feb;142:75-80. doi: 10.1016/j.pep.2017.10.006. Epub 2017 Oct 5.

PMID:
28988145
27.

DNA-Loaded Cationic Liposomes Efficiently Function as a Vaccine against Malarial Proteins.

Fotoran WL, Santangelo R, de Miranda BNM, Irvine DJ, Wunderlich G.

Mol Ther Methods Clin Dev. 2017 Aug 23;7:1-10. doi: 10.1016/j.omtm.2017.08.004. eCollection 2017 Dec 15.

28.

TLR4-Mediated Placental Pathology and Pregnancy Outcome in Experimental Malaria.

Barboza R, Lima FA, Reis AS, Murillo OJ, Peixoto EPM, Bandeira CL, Fotoran WL, Sardinha LR, Wunderlich G, Bevilacqua E, Lima MRD, Alvarez JM, Costa FTM, Gonçalves LA, Epiphanio S, Marinho CRF.

Sci Rep. 2017 Aug 17;7(1):8623. doi: 10.1038/s41598-017-08299-x. Erratum in: Sci Rep. 2018 Mar 6;8(1):4275.

29.

Knockdown of the Plasmodium falciparum SURFIN4.1 antigen leads to an increase of its cognate transcript.

Macedo-Silva T, Araujo RBD, Meissner KA, Fotoran WL, Medeiros MM, de Azevedo MF, Wunderlich G.

PLoS One. 2017 Aug 11;12(8):e0183129. doi: 10.1371/journal.pone.0183129. eCollection 2017.

30.

[30-year-old Patient with suspected Marfan Syndrome and Progressive Gait disturbance].

Balke M, Lehmann HC, Fink GR, Wunderlich G.

Dtsch Med Wochenschr. 2017 Jul;142(13):982-985. doi: 10.1055/s-0043-106279. Epub 2017 Jul 3. German.

PMID:
28672420
31.

Lymphocyte antigens targetable by monoclonal antibodies in non-systemic vasculitic neuropathy.

Schneider C, Wunderlich G, Bleistein J, Fink GR, Deckert M, Brunn A, Lehmann HC.

J Neurol Neurosurg Psychiatry. 2017 Sep;88(9):756-760. doi: 10.1136/jnnp-2017-315878. Epub 2017 May 26.

PMID:
28550073
32.

["Therapy-resistant polymyositis" - is the diagnosis correct?]

Ceccon G, Lehmann HC, Neuen-Jacob E, Meng G, Fink GR, Wunderlich G.

Z Rheumatol. 2017 Sep;76(7):640-643. doi: 10.1007/s00393-017-0326-0. German.

PMID:
28523511
33.

Twins in spirit part IV - [177Lu] high affinity DOTATATE. A promising new tracer for peptide receptor radiotherapy?

Brogsitter C, Hartmann H, Wunderlich G, Schottelius M, Wester HJ, Kotzerke J.

Nuklearmedizin. 2017 Feb 14;56(1):1-8. doi: 10.3413/Nukmed-0860-16-11. Epub 2017 Jan 31.

PMID:
28138688
34.

Erratum to: "Reduced-Intensity Conditioning Combined with 188Rhenium Radioimmunotherapy before Allogeneic Hematopoietic Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia: The Role of in Vivo T Cell Depletion" [Biol Blood Marrow Transplant 2015;21:1754-1760].

Schneider S, Strumpf A, Schetelig J, Wunderlich G, Ehninger G, Kotzerke J, Bornhäuser M.

Biol Blood Marrow Transplant. 2017 Mar;23(3):533. doi: 10.1016/j.bbmt.2016.12.626. Epub 2017 Jan 6. No abstract available.

35.

[Chronic Inflammatory Demyelinating Polyneuropathy].

Balke M, Wunderlich G, Brunn A, Fink GR, Lehmann HC.

Fortschr Neurol Psychiatr. 2016 Dec;84(12):756-769. Epub 2016 Dec 12. Review. German.

PMID:
27951607
36.

Expressed var gene repertoire and variant surface antigen diversity in a shrinking Plasmodium falciparum population.

Carlos BC, Fotoran WL, Menezes MJ, Cabral FJ, Bastos MF, Costa FTM, Sousa-Neto JA, Ribolla PEM, Wunderlich G, Ferreira MU.

Exp Parasitol. 2016 Nov;170:90-99. doi: 10.1016/j.exppara.2016.09.006. Epub 2016 Sep 20.

PMID:
27663467
37.

Direct and Auger Electron-Induced, Single- and Double-Strand Breaks on Plasmid DNA Caused by 99mTc-Labeled Pyrene Derivatives and the Effect of Bonding Distance.

Reissig F, Mamat C, Steinbach J, Pietzsch HJ, Freudenberg R, Navarro-Retamal C, Caballero J, Kotzerke J, Wunderlich G.

PLoS One. 2016 Sep 1;11(9):e0161973. doi: 10.1371/journal.pone.0161973. eCollection 2016.

38.

Oligosymptomatic adrenomyeloneuropathy due to a novel mutation in the ABCD1 start codon.

Dunkl V, Rau I, Wunderlich G, Fink GR, Lehmann HC.

J Neurol Sci. 2016 Aug 15;367:81-2. doi: 10.1016/j.jns.2016.05.047. Epub 2016 May 24. No abstract available.

PMID:
27423567
39.

Comparison of the radiotoxicity of the 99mTc-labeled compounds 99mTc-pertechnetate, 99mTc-HMPAO and 99mTc-MIBI.

Maucksch U, Runge R, Wunderlich G, Freudenberg R, Naumann A, Kotzerke J.

Int J Radiat Biol. 2016 Nov;92(11):698-706. Epub 2016 Apr 27.

PMID:
27117205
40.

Single-target high-throughput transcription analyses reveal high levels of alternative splicing present in the FPPS/GGPPS from Plasmodium falciparum.

Gabriel HB, de Azevedo MF, Palmisano G, Wunderlich G, Kimura EA, Katzin AM, Alves JM.

Sci Rep. 2015 Dec 21;5:18429. doi: 10.1038/srep18429.

41.

Merozoite surface protein-1 genetic diversity in Plasmodium malariae and Plasmodium brasilianum from Brazil.

Guimarães LO, Wunderlich G, Alves JM, Bueno MG, Röhe F, Catão-Dias JL, Neves A, Malafronte RS, Curado I, Domingues W, Kirchgatter K.

BMC Infect Dis. 2015 Nov 16;15:529. doi: 10.1186/s12879-015-1238-8.

42.

Liposomes loaded with P. falciparum merozoite-derived proteins are highly immunogenic and produce invasion-inhibiting and anti-toxin antibodies.

Fotoran WL, Santangelo RM, Medeiros MM, Colhone M, Ciancaglini P, Barboza R, Marinho CR, Stábeli RG, Wunderlich G.

J Control Release. 2015 Nov 10;217:121-7. doi: 10.1016/j.jconrel.2015.08.045. Epub 2015 Aug 31.

PMID:
26334481
43.

[Chemotherapy-induced Peripheral Neuropathy].

Bobylev I, Elter T, Schneider C, Wunderlich G, Zimmer P, Streckmann F, Fink GR, Lehmann HC.

Fortschr Neurol Psychiatr. 2015 Aug;83(8):427-36. doi: 10.1055/s-0035-1553475. Epub 2015 Sep 1. Review. German.

PMID:
26327474
44.

Immunization with the MAEBL M2 Domain Protects against Lethal Plasmodium yoelii Infection.

Leite JA, Bargieri DY, Carvalho BO, Albrecht L, Lopes SC, Kayano AC, Farias AS, Chia WN, Claser C, Malleret B, Russell B, Castiñeiras C, Santos LM, Brocchi M, Wunderlich G, Soares IS, Rodrigues MM, Rénia L, Costa FT.

Infect Immun. 2015 Oct;83(10):3781-92. doi: 10.1128/IAI.00262-15. Epub 2015 Jul 13.

45.

Reduced-Intensity Conditioning Combined with (188)Rhenium Radioimmunotherapy before Allogeneic Hematopoietic Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia: The Role of In Vivo T Cell Depletion.

Schneider S, Strumpf A, Schetelig J, Wunderlich G, Ehninger G, Kotzerke J, Bornhäuser M.

Biol Blood Marrow Transplant. 2015 Oct;21(10):1754-60. doi: 10.1016/j.bbmt.2015.05.012. Epub 2015 May 19. Erratum in: Biol Blood Marrow Transplant. 2017 Mar;23(3):533.

46.

Squalestatin is an inhibitor of carotenoid biosynthesis in Plasmodium falciparum.

Gabriel HB, Silva MF, Kimura EA, Wunderlich G, Katzin AM, Azevedo MF.

Antimicrob Agents Chemother. 2015;59(6):3180-8. doi: 10.1128/AAC.04500-14. Epub 2015 Mar 16.

47.

[25-year old patient with angina pectoris during religious fasting].

Huber CA, Wunderlich G, Brunn A, Blau T, Fink GR, Lehmann HC.

Dtsch Med Wochenschr. 2015 Feb;140(3):202-5. doi: 10.1055/s-0041-100076. Epub 2015 Feb 6. German.

PMID:
25658411
48.

Theranostic mercury: (197(m))Hg with high specific activity for imaging and therapy.

Walther M, Preusche S, Bartel S, Wunderlich G, Freudenberg R, Steinbach J, Pietzsch HJ.

Appl Radiat Isot. 2015 Mar;97:177-181. doi: 10.1016/j.apradiso.2015.01.001. Epub 2015 Jan 5.

PMID:
25588997
49.

Anopheles (Kerteszia) cruzii (Diptera: Culicidae) in peridomiciliary area during asymptomatic malaria transmission in the Atlantic Forest: molecular identification of blood-meal sources indicates humans as primary intermediate hosts.

Kirchgatter K, Tubaki RM, Malafronte Rdos S, Alves IC, Lima GF, Guimarães Lde O, Zampaulo Rde A, Wunderlich G.

Rev Inst Med Trop Sao Paulo. 2014 Sep-Oct;56(5):403-9.

50.

Antibody recognition of Plasmodium falciparum infected red blood cells by symptomatic and asymptomatic individuals in the Brazilian Amazon.

Fratus AS, Cabral FJ, Fotoran WL, Medeiros MM, Carlos BC, Martha Rd, da Silva LH, Lopes SC, Costa FT, Wunderlich G.

Mem Inst Oswaldo Cruz. 2014 Aug;109(5):598-601. Epub 2014 Aug 5.

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