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Items: 1 to 50 of 269

1.

Expanding the Reaction Space of Linkage-Specific Sialic Acid Derivatization.

Pongracz T, Wuhrer M, de Haan N.

Molecules. 2019 Oct 8;24(19). pii: E3617. doi: 10.3390/molecules24193617.

2.

NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods.

De Leoz MLA, Duewer DL, Fung A, Liu L, Yau HK, Potter O, Staples GO, Furuki K, Frenkel R, Hu Y, Sosic Z, Zhang P, Altmann F, Gruber C, Shao C, Zaia J, Evers W, Pangelley S, Suckau D, Wiechmann A, Resemann A, Jabs W, Beck A, Froehlich JW, Huang C, Li Y, Liu Y, Sun S, Wang Y, Seo Y, An HJ, Reichardt NC, Ruiz JE, Archer-Hartmann S, Azadi P, Bell L, Lakos Z, An Y, Cipollo JF, Pučić-Baković M, Štambuk J, Lauc G, Li X, Wang PG, Bock A, Hennig R, Rapp E, Creskey M, Cyr T, Nakano M, Sugiyama T, Leung PA, Link-Lenczowski P, Jaworek J, Yang SJ, Zhang H, Kelly T, Klapoetke S, Cao R, Kim JY, Lee HK, Lee J, Yoo JS, Kim SR, Suh SK, de Haan N, Falck D, Lageveen-Kammeijer GSM, Wuhrer M, Emery RJ, Kozak RP, Liew LP, Royle L, Urbanowicz PA, Packer N, Song X, Everest-Dass A, Lattová E, Cajic S, Alagesan K, Kolarich D, Kasali T, Lindo V, Chen Y, Goswami K, Gau B, Amunugama R, Jones R, Stroop CJM, Kato K, Yagi H, Kondo S, Yuen CT, Harazono A, Shi X, Magnelli P, Kasper BT, Mahal LK, Harvey DJ, O'Flaherty RM, Rudd P, Saldova R, Hecht ES, Muddiman DC, Kang J, Bhoskar P, Menard D, Saati A, Merle C, Mast S, Tep S, Truong J, Nishikaze T, Sekiya S, Shafer A, Funaoka S, Toyoda M, de Vreugd P, Caron C, Pradhan P, Tan NC, Mechref Y, Patil S, Rohrer JS, Chakrabarti R, Dadke D, Lahori M, Zou C, Cairo CW, Reiz B, Whittal RM, Lebrilla C, Wu LD, Guttman A, Szigeti M, Kremkow BG, Lee K, Sihlbom C, Adamczyk B, Jin C, Karlsson NG, Örnros J, Larson G, Nilsson J, Meyer B, Wiegandt A, Komatsu E, Perreault H, Bodnar ED, Said N, Francois YN, Leize-Wagner E, Maier S, Zeck A, Heck AJR, Yang Y, Haselberg R, Yu YQ, Alley W, Leone JW, Yuan H, Stein SE.

Mol Cell Proteomics. 2019 Oct 7. pii: mcp.RA119.001677. doi: 10.1074/mcp.RA119.001677. [Epub ahead of print]

3.

Paucity of Paucimannosylation Revoked.

Wuhrer M.

Proteomics. 2019 Sep 18:e1900244. doi: 10.1002/pmic.201900244. [Epub ahead of print]

PMID:
31532879
4.

N-glycome signatures in human plasma: associations with physiology and major diseases.

Dotz V, Wuhrer M.

FEBS Lett. 2019 Sep 11. doi: 10.1002/1873-3468.13598. [Epub ahead of print] Review.

PMID:
31509238
5.

On the presence of HLA-SE alleles and ACPA-IgG variable domain glycosylation in the phase preceding the development of rheumatoid arthritis.

Kissel T, van Schie KA, Hafkenscheid L, Lundquist A, Kokkonen H, Wuhrer M, Huizinga TW, Scherer HU, Toes R, Rantapää-Dahlqvist S.

Ann Rheum Dis. 2019 Aug 30. pii: annrheumdis-2019-215698. doi: 10.1136/annrheumdis-2019-215698. [Epub ahead of print]

PMID:
31471298
6.

Dried blood spot N-glycome analysis by MALDI mass spectrometry.

Vreeker GCM, Bladergroen MR, Nicolardi S, Mesker WE, Tollenaar RAEM, van der Burgt YEM, Wuhrer M.

Talanta. 2019 Dec 1;205:120104. doi: 10.1016/j.talanta.2019.06.104. Epub 2019 Jun 29.

7.

Recombinant human monoclonal HLA antibodies of different IgG subclasses recognising the same epitope: Excellent tools to study differential effects of donor-specific antibodies.

Kramer CSM, Franke-van Dijk MEI, Priddey AJ, Pongrácz T, Gnudi E, Car H, Karahan GE, van Beelen E, Zilvold-van den Oever CCC, Rademaker HJ, de Haan N, Wuhrer M, Kosmoliaptsis V, Parren PWHI, Mulder A, Roelen DL, Claas FHJ, Heidt S.

HLA. 2019 Aug 12. doi: 10.1111/tan.13664. [Epub ahead of print]

PMID:
31403241
8.

OGT Controls the Expression and the Glycosylation of E-cadherin, and Affects Glycosphingolipid Structures in Human Colon Cell Lines.

Biwi J, Clarisse C, Biot C, Kozak RP, Madunic K, Mortuaire M, Wuhrer M, Spencer DIR, Schulz C, Guerardel Y, Lefebvre T, Vercoutter-Edouart AS.

Proteomics. 2019 Aug 2:e1800452. doi: 10.1002/pmic.201800452. [Epub ahead of print]

PMID:
31373757
9.

Site-specific N- and O-glycosylation analysis of atacicept.

Stavenhagen K, Gahoual R, Dominguez Vega E, Palmese A, Ederveen ALH, Cutillo F, Palinsky W, Bierau H, Wuhrer M.

MAbs. 2019 Aug/Sep;11(6):1053-1063. doi: 10.1080/19420862.2019.1630218. Epub 2019 Jul 26.

10.

Characterization and prediction of positional 4-hydroxyproline and sulfotyrosine, two post-translational modifications that can occur at substantial levels in CHO cells-expressed biotherapeutics.

Tyshchuk O, Gstöttner C, Funk D, Nicolardi S, Frost S, Klostermann S, Becker T, Jolkver E, Schumacher F, Koller CF, Völger HR, Wuhrer M, Bulau P, Mølhøj M.

MAbs. 2019 Oct;11(7):1219-1232. doi: 10.1080/19420862.2019.1635865. Epub 2019 Jul 24.

11.

Towards a standardized bioinformatics infrastructure for N- and O-glycomics.

Rojas-Macias MA, Mariethoz J, Andersson P, Jin C, Venkatakrishnan V, Aoki NP, Shinmachi D, Ashwood C, Madunic K, Zhang T, Miller RL, Horlacher O, Struwe WB, Watanabe Y, Okuda S, Levander F, Kolarich D, Rudd PM, Wuhrer M, Kettner C, Packer NH, Aoki-Kinoshita KF, Lisacek F, Karlsson NG.

Nat Commun. 2019 Jul 22;10(1):3275. doi: 10.1038/s41467-019-11131-x. Review.

PMID:
31332201
12.

Human DC-SIGN and CD23 do not interact with human IgG.

Temming AR, Dekkers G, van de Bovenkamp FS, Plomp HR, Bentlage AEH, Szittner Z, Derksen NIL, Wuhrer M, Rispens T, Vidarsson G.

Sci Rep. 2019 Jul 10;9(1):9995. doi: 10.1038/s41598-019-46484-2.

13.

Monitoring of Immunoglobulin N- and O-glycosylation in Health and Disease.

de Haan N, Falck D, Wuhrer M.

Glycobiology. 2019 Jul 8. pii: cwz048. doi: 10.1093/glycob/cwz048. [Epub ahead of print]

PMID:
31281930
14.

Glycoform-resolved FcɣRIIIa affinity chromatography-mass spectrometry.

Lippold S, Nicolardi S, Domínguez-Vega E, Heidenreich AK, Vidarsson G, Reusch D, Haberger M, Wuhrer M, Falck D.

MAbs. 2019 Oct;11(7):1191-1196. doi: 10.1080/19420862.2019.1636602. Epub 2019 Aug 2.

15.

The Glycosylation Site of Myelin Oligodendrocyte Glycoprotein Affects Autoantibody Recognition in a Large Proportion of Patients.

Marti Fernandez I, Macrini C, Krumbholz M, Hensbergen PJ, Hipgrave Ederveen AL, Winklmeier S, Vural A, Kurne A, Jenne D, Kamp F, Gerdes LA, Hohlfeld R, Wuhrer M, Kümpfel T, Meinl E.

Front Immunol. 2019 Jun 11;10:1189. doi: 10.3389/fimmu.2019.01189. eCollection 2019.

16.

Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples.

Lageveen-Kammeijer GSM, de Haan N, Mohaupt P, Wagt S, Filius M, Nouta J, Falck D, Wuhrer M.

Nat Commun. 2019 May 13;10(1):2137. doi: 10.1038/s41467-019-09910-7.

17.

N-Linked Glycans in the Variable Domain of IgG Anti-Citrullinated Protein Antibodies Predict the Development of Rheumatoid Arthritis.

Hafkenscheid L, de Moel E, Smolik I, Tanner S, Meng X, Jansen BC, Bondt A, Wuhrer M, Huizinga TWJ, Toes REM, El-Gabalawy H, Scherer HU.

Arthritis Rheumatol. 2019 Oct;71(10):1626-1633. doi: 10.1002/art.40920. Epub 2019 Sep 2.

PMID:
31067000
18.

N-Glycomic and Transcriptomic Changes Associated with CDX1 mRNA Expression in Colorectal Cancer Cell Lines.

Holst S, Wilding JL, Koprowska K, Rombouts Y, Wuhrer M.

Cells. 2019 Mar 22;8(3). pii: E273. doi: 10.3390/cells8030273.

19.

Serum protein N-glycosylation changes in multiple myeloma.

Zhang Z, Westhrin M, Bondt A, Wuhrer M, Standal T, Holst S.

Biochim Biophys Acta Gen Subj. 2019 May;1863(5):960-970. doi: 10.1016/j.bbagen.2019.03.001. Epub 2019 Mar 5.

PMID:
30844485
20.

The Role of Glycosphingolipids in Immune Cell Functions.

Zhang T, de Waard AA, Wuhrer M, Spaapen RM.

Front Immunol. 2019 Jan 29;10:90. doi: 10.3389/fimmu.2019.00090. eCollection 2019. Review.

21.

Improved and semi-automated reductive β-elimination workflow for higher throughput protein O-glycosylation analysis.

Kotsias M, Kozak RP, Gardner RA, Wuhrer M, Spencer DIR.

PLoS One. 2019 Jan 17;14(1):e0210759. doi: 10.1371/journal.pone.0210759. eCollection 2019.

22.

Glycoproteomic Analysis of MGL-Binding Proteins on Acute T-Cell Leukemia Cells.

Pirro M, Schoof E, van Vliet SJ, Rombouts Y, Stella A, de Ru A, Mohammed Y, Wuhrer M, van Veelen PA, Hensbergen PJ.

J Proteome Res. 2019 Mar 1;18(3):1125-1132. doi: 10.1021/acs.jproteome.8b00796. Epub 2019 Jan 9.

23.

Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry.

van der Burgt YEM, Kilgour DPA, Tsybin YO, Srzentić K, Fornelli L, Beck A, Wuhrer M, Nicolardi S.

Anal Chem. 2019 Feb 5;91(3):2079-2085. doi: 10.1021/acs.analchem.8b04515. Epub 2019 Jan 8.

24.

α1-Antichymotrypsin Present in Therapeutic C1-Inhibitor Products Competes with Selectin-Sialyl LewisX Interaction.

Engel R, Delvasto-Nuñez L, Roem D, van Mierlo G, Holst S, Hipgrave Ederveen AL, van Buul JD, Wuhrer M, Wouters D, Zeerleder S.

Thromb Haemost. 2018 Dec;118(12):2134-2144. doi: 10.1055/s-0038-1675601. Epub 2018 Nov 19.

PMID:
30453343
25.

Comparative Glycomics of Immunoglobulin A and G From Saliva and Plasma Reveals Biomarker Potential.

Plomp R, de Haan N, Bondt A, Murli J, Dotz V, Wuhrer M.

Front Immunol. 2018 Oct 23;9:2436. doi: 10.3389/fimmu.2018.02436. eCollection 2018.

26.

Unique patterns of glycosylation in immunoglobulin subclass G4-related disease and primary sclerosing cholangitis.

Culver EL, van de Bovenkamp FS, Derksen NIL, Koers J, Cargill T, Barnes E, de Neef LA, Koeleman CAM, Aalberse RC, Wuhrer M, Rispens T.

J Gastroenterol Hepatol. 2018 Oct 21. doi: 10.1111/jgh.14512. [Epub ahead of print]

PMID:
30345709
27.

Plasma protein N-glycan signatures of type 2 diabetes.

Dotz V, Lemmers RFH, Reiding KR, Hipgrave Ederveen AL, Lieverse AG, Mulder MT, Sijbrands EJG, Wuhrer M, van Hoek M.

Biochim Biophys Acta Gen Subj. 2018 Dec;1862(12):2613-2622. doi: 10.1016/j.bbagen.2018.08.005. Epub 2018 Aug 6.

PMID:
30251656
28.

High-throughput Serum N-Glycomics: Method Comparison and Application to Study Rheumatoid Arthritis and Pregnancy-associated Changes.

Reiding KR, Bondt A, Hennig R, Gardner RA, O'Flaherty R, Trbojević-Akmačić I, Shubhakar A, Hazes JMW, Reichl U, Fernandes DL, Pučić-Baković M, Rapp E, Spencer DIR, Dolhain RJEM, Rudd PM, Lauc G, Wuhrer M.

Mol Cell Proteomics. 2019 Jan;18(1):3-15. doi: 10.1074/mcp.RA117.000454. Epub 2018 Sep 21.

PMID:
30242110
29.

Automated Plasma Glycomics with Linkage-Specific Sialic Acid Esterification and Ultrahigh Resolution MS.

Vreeker GCM, Nicolardi S, Bladergroen MR, van der Plas CJ, Mesker WE, Tollenaar RAEM, van der Burgt YEM, Wuhrer M.

Anal Chem. 2018 Oct 16;90(20):11955-11961. doi: 10.1021/acs.analchem.8b02391. Epub 2018 Oct 3.

30.

Serum N-glycome alterations in colorectal cancer associate with survival.

de Vroome SW, Holst S, Girondo MR, van der Burgt YEM, Mesker WE, Tollenaar RAEM, Wuhrer M.

Oncotarget. 2018 Jul 17;9(55):30610-30623. doi: 10.18632/oncotarget.25753. eCollection 2018 Jul 17.

31.

Trace N-glycans including sulphated species may originate from various plasma glycoproteins and not necessarily IgG.

Lauc G, Vučković F, Bondt A, Pezer M, Wuhrer M.

Nat Commun. 2018 Jul 25;9(1):2916. doi: 10.1038/s41467-018-05173-w. No abstract available.

32.

Biophysical analysis of sialic acid recognition by the complement regulator Factor H.

Schmidt CQ, Hipgrave Ederveen AL, Harder MJ, Wuhrer M, Stehle T, Blaum BS.

Glycobiology. 2018 Oct 1;28(10):765-773. doi: 10.1093/glycob/cwy061.

33.

HappyTools: A software for high-throughput HPLC data processing and quantitation.

Jansen BC, Hafkenscheid L, Bondt A, Gardner RA, Hendel JL, Wuhrer M, Spencer DIR.

PLoS One. 2018 Jul 6;13(7):e0200280. doi: 10.1371/journal.pone.0200280. eCollection 2018.

34.

Restricted immune activation and internalisation of anti-idiotype complexes between drug and antidrug antibodies.

van Schie KA, Kruithof S, Ooijevaar-de Heer P, Derksen NIL, van de Bovenkamp FS, Saris A, Vidarsson G, Bentlage AEH, Jiskoot W, Romeijn S, Koning RI, Bos E, Stork EM, Koeleman CAM, Wuhrer M, Wolbink G, Rispens T.

Ann Rheum Dis. 2018 Oct;77(10):1471-1479. doi: 10.1136/annrheumdis-2018-213299. Epub 2018 Jun 26.

PMID:
29945923
35.

Differences in IgG Fc Glycosylation Are Associated with Outcome of Pediatric Meningococcal Sepsis.

de Haan N, Boeddha NP, Ekinci E, Reiding KR, Emonts M, Hazelzet JA, Wuhrer M, Driessen GJ.

MBio. 2018 Jun 19;9(3). pii: e00546-18. doi: 10.1128/mBio.00546-18.

36.

Immunoglobulin G Fragment Crystallizable Glycosylation After Hematopoietic Stem Cell Transplantation Is Dissimilar to Donor Profiles.

de Haan N, van Tol MJD, Driessen GJ, Wuhrer M, Lankester AC.

Front Immunol. 2018 Jun 4;9:1238. doi: 10.3389/fimmu.2018.01238. eCollection 2018.

37.

Plasma N-Glycan Signatures Are Associated With Features of Inflammatory Bowel Diseases.

Clerc F, Novokmet M, Dotz V, Reiding KR, de Haan N, Kammeijer GSM, Dalebout H, Bladergroen MR, Vukovic F, Rapp E; IBD-BIOM Consortium, Targan SR, Barron G, Manetti N, Latiano A, McGovern DPB, Annese V, Lauc G, Wuhrer M.

Gastroenterology. 2018 Sep;155(3):829-843. doi: 10.1053/j.gastro.2018.05.030. Epub 2018 May 21.

PMID:
29792883
38.

Low amounts of bisecting glycans characterize cerebrospinal fluid-borne IgG.

Knopf J, Magorivska I, Maler JM, Spitzer P, Bilyy R, Biermann MHC, Hychka K, Bondt A, Wuhrer M, Toes REM, Schett G, Herrmann M, Muñoz LE.

J Neuroimmunol. 2018 Jul 15;320:19-24. doi: 10.1016/j.jneuroim.2018.04.010. Epub 2018 Apr 16.

PMID:
29759137
39.

Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: a potential explanation for the increased risk of rheumatoid arthritis in postmenopausal women.

Engdahl C, Bondt A, Harre U, Raufer J, Pfeifle R, Camponeschi A, Wuhrer M, Seeling M, Mårtensson IL, Nimmerjahn F, Krönke G, Scherer HU, Forsblad-d'Elia H, Schett G.

Arthritis Res Ther. 2018 May 2;20(1):84. doi: 10.1186/s13075-018-1586-z.

40.

Serum sialylation changes in cancer.

Zhang Z, Wuhrer M, Holst S.

Glycoconj J. 2018 Apr;35(2):139-160. doi: 10.1007/s10719-018-9820-0. Epub 2018 Apr 21. Review.

41.

ACPA IgG galactosylation associates with disease activity in pregnant patients with rheumatoid arthritis.

Bondt A, Hafkenscheid L, Falck D, Kuijper TM, Rombouts Y, Hazes JMW, Wuhrer M, Dolhain RJEM.

Ann Rheum Dis. 2018 Aug;77(8):1130-1136. doi: 10.1136/annrheumdis-2018-212946. Epub 2018 Apr 3.

PMID:
29615411
42.

Reformatting palivizumab and motavizumab from IgG to human IgA impairs their efficacy against RSV infection in vitro and in vivo.

Jacobino SR, Nederend M, Reijneveld JF, Augustijn D, Jansen JHM, Meeldijk J, Reiding KR, Wuhrer M, Coenjaerts FEJ, Hack CE, Bont LJ, Leusen JHW.

MAbs. 2018 Apr;10(3):453-462. doi: 10.1080/19420862.2018.1433974. Epub 2018 Mar 19.

43.

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.

Wahl A, van den Akker E, Klaric L, Štambuk J, Benedetti E, Plomp R, Razdorov G, Trbojević-Akmačić I, Deelen J, van Heemst D, Slagboom PE, Vučković F, Grallert H, Krumsiek J, Strauch K, Peters A, Meitinger T, Hayward C, Wuhrer M, Beekman M, Lauc G, Gieger C.

Front Immunol. 2018 Feb 26;9:277. doi: 10.3389/fimmu.2018.00277. eCollection 2018.

44.

An In-Depth Glycosylation Assay for Urinary Prostate-Specific Antigen.

Kammeijer GSM, Nouta J, de la Rosette JJMCH, de Reijke TM, Wuhrer M.

Anal Chem. 2018 Apr 3;90(7):4414-4421. doi: 10.1021/acs.analchem.7b04281. Epub 2018 Mar 14.

45.

The glycomic effect of N-acetylglucosaminyltransferase III overexpression in metastatic melanoma cells. GnT-III modifies highly branched N-glycans.

Link-Lenczowski P, Bubka M, Balog CIA, Koeleman CAM, Butters TD, Wuhrer M, Lityńska A.

Glycoconj J. 2018 Apr;35(2):217-231. doi: 10.1007/s10719-018-9814-y. Epub 2018 Mar 3.

46.

Fc-Glycosylation in Human IgG1 and IgG3 Is Similar for Both Total and Anti-Red-Blood Cell Anti-K Antibodies.

Sonneveld ME, Koeleman CAM, Plomp HR, Wuhrer M, van der Schoot CE, Vidarsson G.

Front Immunol. 2018 Jan 31;9:129. doi: 10.3389/fimmu.2018.00129. eCollection 2018.

47.

Publisher Correction: Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway.

Benedetti E, Pučić-Baković M, Keser T, Wahl A, Hassinen A, Yang JY, Liu L, Trbojević-Akmačić I, Razdorov G, Štambuk J, Klarić L, Ugrina I, Selman MHJ, Wuhrer M, Rudan I, Polasek O, Hayward C, Grallert H, Strauch K, Peters A, Meitinger T, Gieger C, Vilaj M, Boons GJ, Moremen KW, Ovchinnikova T, Bovin N, Kellokumpu S, Theis FJ, Lauc G, Krumsiek J.

Nat Commun. 2018 Feb 13;9(1):706. doi: 10.1038/s41467-017-02379-2.

48.

Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region.

van de Bovenkamp FS, Derksen NIL, Ooijevaar-de Heer P, van Schie KA, Kruithof S, Berkowska MA, van der Schoot CE, IJspeert H, van der Burg M, Gils A, Hafkenscheid L, Toes REM, Rombouts Y, Plomp R, Wuhrer M, van Ham SM, Vidarsson G, Rispens T.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1901-1906. doi: 10.1073/pnas.1711720115. Epub 2018 Feb 5.

49.

Cutis laxa, exocrine pancreatic insufficiency and altered cellular metabolomics as additional symptoms in a new patient with ATP6AP1-CDG.

Dimitrov B, Himmelreich N, Hipgrave Ederveen AL, Lüchtenborg C, Okun JG, Breuer M, Hutter AM, Carl M, Guglielmi L, Hellwig A, Thiemann KC, Jost M, Peters V, Staufner C, Hoffmann GF, Hackenberg A, Paramasivam N, Wiemann S, Eils R, Schlesner M, Strahl S, Brügger B, Wuhrer M, Christoph Korenke G, Thiel C.

Mol Genet Metab. 2018 Mar;123(3):364-374. doi: 10.1016/j.ymgme.2018.01.008. Epub 2018 Jan 31.

PMID:
29396028
50.

Serum Protein N-Glycosylation Changes with Rheumatoid Arthritis Disease Activity during and after Pregnancy.

Reiding KR, Vreeker GCM, Bondt A, Bladergroen MR, Hazes JMW, van der Burgt YEM, Wuhrer M, Dolhain RJEM.

Front Med (Lausanne). 2018 Jan 8;4:241. doi: 10.3389/fmed.2017.00241. eCollection 2017.

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