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Effect of Intravenous Tenecteplase Dose on Cerebral Reperfusion Before Thrombectomy in Patients With Large Vessel Occlusion Ischemic Stroke: The EXTEND-IA TNK Part 2 Randomized Clinical Trial.

Campbell BCV, Mitchell PJ, Churilov L, Yassi N, Kleinig TJ, Dowling RJ, Yan B, Bush SJ, Thijs V, Scroop R, Simpson M, Brooks M, Asadi H, Wu TY, Shah DG, Wijeratne T, Zhao H, Alemseged F, Ng F, Bailey P, Rice H, de Villiers L, Dewey HM, Choi PMC, Brown H, Redmond K, Leggett D, Fink JN, Collecutt W, Kraemer T, Krause M, Cordato D, Field D, Ma H, O'Brien B, Clissold B, Miteff F, Clissold A, Cloud GC, Bolitho LE, Bonavia L, Bhattacharya A, Wright A, Mamun A, O'Rourke F, Worthington J, Wong AA, Levi CR, Bladin CF, Sharma G, Desmond PM, Parsons MW, Donnan GA, Davis SM; EXTEND-IA TNK Part 2 investigators.

JAMA. 2020 Feb 20. doi: 10.1001/jama.2020.1511. [Epub ahead of print]


Risk factors for treatment resistance and relapse of Chinese patients with MPO-ANCA-associated vasculitis.

Huang L, Shen C, Zhong Y, Ooi JD, Zhou YO, Chen JB, Wu T, Meng T, Xiao Z, Lin W, Ao X, Xiao X, Zhou Q, Xiao P.

Clin Exp Med. 2020 Feb 20. doi: 10.1007/s10238-020-00614-7. [Epub ahead of print]


Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133.

Liu YA, Jin Q, Zou Y, Ding Q, Yan S, Wang Z, Hao X, Nguyen B, Zhang X, Pan J, Mo T, Jacobsen K, Lam T, Wu TY, Petrassi HM, Bursulaya B, DiDonato M, Gordon WP, Liu B, Baaten J, Hill R, Nguyen-Tran V, Qiu M, Zhang YQ, Kamireddy A, Espinola S, Deaton L, Ha S, Harb G, Jia Y, Li J, Shen W, Schumacher AM, Colman K, Glynne R, Pan S, McNamara P, Laffitte B, Meeusen S, Molteni V, Loren J.

J Med Chem. 2020 Feb 20. doi: 10.1021/acs.jmedchem.9b01624. [Epub ahead of print]


Effects of Highly Oxygenated Water in a Hyperuricemia Rat Model.

Fang CH, Tsai CC, Shyong YJ, Yang CT, Li KY, Lin YW, Chang KC, Wang MH, Wu TM, Lin FH.

J Healthc Eng. 2020 Jan 30;2020:1323270. doi: 10.1155/2020/1323270. eCollection 2020.


High-efficiency direct methane conversion to oxygenates on a cerium dioxide nanowires supported rhodium single-atom catalyst.

Bai S, Liu F, Huang B, Li F, Lin H, Wu T, Sun M, Wu J, Shao Q, Xu Y, Huang X.

Nat Commun. 2020 Feb 19;11(1):954. doi: 10.1038/s41467-020-14742-x.


HIRA, a DiGeorge Syndrome Candidate Gene, Confers Proper Chromatin Accessibility on HSCs and Supports All Stages of Hematopoiesis.

Chen C, Sun MA, Warzecha C, Bachu M, Dey A, Wu T, Adams PD, Macfarlan T, Love P, Ozato K.

Cell Rep. 2020 Feb 10. pii: S2211-1247(20)30087-5. doi: 10.1016/j.celrep.2020.01.062. [Epub ahead of print]


[Value of reduction surgery for incurable advanced gastric cancer: Discussion based on REGATTA trial].

Wu T.

Zhonghua Wei Chang Wai Ke Za Zhi. 2020 Feb 25;23(2):134-139. doi: 10.3760/cma.j.issn.1671-0274.2020.02.007. Chinese.


EXPRESS: A Normalized Difference Spectral Recognition Index for Azurite Pigment.

Wu T, Yuan B, Wang S, Lei Y, Li G.

Appl Spectrosc. 2020 Feb 19:3702820909435. doi: 10.1177/0003702820909435. [Epub ahead of print] No abstract available.


Effect of surface charge density on the ice recrystallization inhibition activity of nanocelluloses.

Li T, Zhong Q, Zhao B, Lenaghan S, Wang S, Wu T.

Carbohydr Polym. 2020 Apr 15;234:115863. doi: 10.1016/j.carbpol.2020.115863. Epub 2020 Jan 16.


Vasoactive intestinal peptide stimulates bone marrow-mesenchymal stem cells osteogenesis differentiation by activating Wnt/β-catenin signaling pathway and promotes rat skull defect repair.

Shi L, Feng L, Zhu M, Yang Z, Wu T, Xu J, Liu Y, Lin W, Lo HT, Zhang J, Li G.

Stem Cells Dev. 2020 Feb 19. doi: 10.1089/scd.2019.0148. [Epub ahead of print]


The IL-1 Antagonist Anakinra Attenuates Glioblastoma Aggressiveness by Dampening Tumor-Associated Inflammation.

Hübner M, Effinger D, Wu T, Strauß G, Pogoda K, Kreth FW, Kreth S.

Cancers (Basel). 2020 Feb 13;12(2). pii: E433. doi: 10.3390/cancers12020433.


Evaluation of Models for Predicting the Probability of Malignancy in Patients with Pulmonary Nodules.

Li Y, Hu H, Wu Z, Yan G, Wu T, Liu S, Chen W, Lu Z.

Biosci Rep. 2020 Feb 18. pii: BSR20193875. doi: 10.1042/BSR20193875. [Epub ahead of print]


Long non-coding RNA TP73-AS1 promotes TFAP2B-mediated proliferation, metastasis and invasion in retinoblastoma via decoying of miRNA-874-3p.

Wang L, Wang C, Wu T, Sun F.

J Cell Commun Signal. 2020 Feb 18. doi: 10.1007/s12079-020-00550-x. [Epub ahead of print]


A proposal for a new staging system for extranodal natural killer T-cell lymphoma: a multicenter study from China and Asia Lymphoma Study Group.

Hong H, Li Y, Lim ST, Liang C, Huang H, Yi P, Wu T, Du X, Zhang M, Wang J, Zhu J, Liu T, Meng F, Wu G, Guo Y, Zhu Y, Zhao W, Jin J, Li J, Deng Y, Gu K, Wu X, Ke X, Xie D, Lin D, Peng Z, Wu J, Liu Q, Kim WS, Lin T.

Leukemia. 2020 Feb 17. doi: 10.1038/s41375-020-0740-1. [Epub ahead of print] No abstract available.


Lipopolysaccharide Reverses Hepatic Stellate Cell Activation via Modulation of cMyb, SMADs and C/EBP Transcription Factors.

Sharma A, Verma AK, Kofron M, Kudira R, Miethke A, Wu T, Wang J, Gandhi CR.

Hepatology. 2020 Feb 16. doi: 10.1002/hep.31188. [Epub ahead of print]


Association of variability in uric acid and future clinical outcomes of patient with coronary artery disease undergoing percutaneous coronary intervention.

Lim SS, Yang YL, Chen SC, Wu CH, Huang SS, Chan WL, Lin SJ, Chen JW, Chou CY, Pan JP, Charng MJ, Chen YH, Wu TC, Lu TM, Hsu PF, Huang PH, Cheng HM, Huang CC, Sung SH, Lin YJ, Leu HB.

Atherosclerosis. 2020 Jan 30;297:40-46. doi: 10.1016/j.atherosclerosis.2020.01.025. [Epub ahead of print]


Shall i trust the report? Variable performance of Sanger sequencing revealed by deep sequencing on HIV drug resistance mutation detection.

Chen NY, Kao SW, Liu ZH, Wu TS, Tsai CL, Lin HH, Wong WW, Chang YY, Chen SS, Ku SW.

Int J Infect Dis. 2020 Feb 12. pii: S1201-9712(20)30062-X. doi: 10.1016/j.ijid.2020.02.004. [Epub ahead of print]


Expedite Construction of Various Bridged Polycyclic Skeletons by Palladium-Catalyzed Dearomatization.

Tang W, Mu X, Yu H, Peng H, Xiong W, Wu T.

Angew Chem Int Ed Engl. 2020 Feb 15. doi: 10.1002/anie.202000953. [Epub ahead of print]


Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo.

Ojha R, Nepali K, Chen CH, Chuang KH, Wu TY, Lin TE, Hsu KC, Chao MW, Lai MJ, Lin MH, Huang HL, Chang CD, Pan SL, Chen MC, Liou JP.

Eur J Med Chem. 2020 Jan 23;190:112086. doi: 10.1016/j.ejmech.2020.112086. [Epub ahead of print]


Ten questions concerning the implications of carpet on indoor chemistry and microbiology.

Haines SR, Adams RI, Boor BE, Bruton TA, Downey J, Ferro AR, Gall E, Green BJ, Hegarty B, Horner E, Jacobs DE, Lemieux P, Misztal PK, Morrison G, Perzanowski M, Reponen T, Rush RE, Virgo T, Alkhayri C, Bope A, Cochran S, Cox J, Donohue A, May AA, Nastasi N, Nishioka M, Renninger N, Tian Y, Uebel-Niemeier C, Wilkinson D, Wu T, Zambrana J, Dannemiller KC.

Build Environ. 2019 Dec 18;170:1-16. doi: 10.1016/j.buildenv.2019.106589.


Effects of N-acetylcysteine on the energy status and antioxidant capacity in heart and liver of cold-stressed broilers.

Li C, Peng M, Liao M, Guo S, Hou Y, Ding B, Wu T, Yi D.

Asian-Australas J Anim Sci. 2019 Nov 12. doi: 10.5713/ajas.19.0542. [Epub ahead of print]


Jasmonate and Ethylene-Regulated Ethylene Response Factor 22 Promotes Lanolin-Induced Anthocyanin Biosynthesis in 'Zaosu' Pear (Pyrus bretschneideri Rehd.) Fruit.

Wu T, Liu HT, Zhao GP, Song JX, Wang XL, Yang CQ, Zhai R, Wang ZG, Ma FW, Xu LF.

Biomolecules. 2020 Feb 11;10(2). pii: E278. doi: 10.3390/biom10020278.


Mammalian ALKBH1 serves as an N6-mA demethylase of unpairing DNA.

Zhang M, Yang S, Nelakanti R, Zhao W, Liu G, Li Z, Liu X, Wu T, Xiao A, Li H.

Cell Res. 2020 Feb 12. doi: 10.1038/s41422-019-0237-5. [Epub ahead of print]


Myocardial tissue-specific Dnmt1 knockout in rats protects against pathological injury induced by Adriamycin.

Wu TT, Ma YW, Zhang X, Dong W, Gao S, Wang JZ, Zhang LF, Lu D.

Lab Invest. 2020 Feb 12. doi: 10.1038/s41374-020-0402-y. [Epub ahead of print]


Vapor-liquid-solid growth of large-area multilayer hexagonal boron nitride on dielectric substrates.

Shi Z, Wang X, Li Q, Yang P, Lu G, Jiang R, Wang H, Zhang C, Cong C, Liu Z, Wu T, Wang H, Yu Q, Xie X.

Nat Commun. 2020 Feb 12;11(1):849. doi: 10.1038/s41467-020-14596-3.


Facilitating ventilator weaning through rib fixation combined with video-assisted thoracoscopic surgery in severe blunt chest injury with acute respiratory failure.

Wu TH, Lin HL, Chou YP, Huang FD, Huang WY, Tarng YW.

Crit Care. 2020 Feb 12;24(1):49. doi: 10.1186/s13054-020-2755-4.


Association of Depression With All-Cause and Cardiovascular Disease Mortality Among Adults in China.

Meng R, Yu C, Liu N, He M, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Zhang X, Chen Z, Wu T, Pan A, Li L; China Kadoorie Biobank Collaborative Group.

JAMA Netw Open. 2020 Feb 5;3(2):e1921043. doi: 10.1001/jamanetworkopen.2019.21043.


Consistent detection of 2019 novel coronavirus in saliva.

To KK, Tsang OT, Chik-Yan Yip C, Chan KH, Wu TC, Chan JMC, Leung WS, Chik TS, Choi CY, Kandamby DH, Lung DC, Tam AR, Poon RW, Fung AY, Hung IF, Cheng VC, Chan JF, Yuen KY.

Clin Infect Dis. 2020 Feb 12. pii: ciaa149. doi: 10.1093/cid/ciaa149. [Epub ahead of print]


Recombinant Lactococcus lactis Expressing Ling Zhi 8 Protein Ameliorates Nonalcoholic Fatty Liver and Early Atherogenesis in Cholesterol-Fed Rabbits.

Lee MF, Chiang CH, Lin SJ, Song PP, Liu HC, Wu TJ, Lin WW.

Biomed Res Int. 2020 Jan 27;2020:3495682. doi: 10.1155/2020/3495682. eCollection 2020.


Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.

Li B, Zhu F, He F, Huang Q, Liu X, Wu T, Zhao T, Qiu Y, Wu Z, Xue Y, Fang M.

Bioorg Chem. 2020 Jan 20;96:103592. doi: 10.1016/j.bioorg.2020.103592. [Epub ahead of print]


PEDV enters cells through clathrin-, caveolae-, and lipid raft-mediated endocytosis and traffics via the endo-/lysosome pathway.

Wei X, She G, Wu T, Xue C, Cao Y.

Vet Res. 2020 Feb 10;51(1):10. doi: 10.1186/s13567-020-0739-7.


Production of H2-Rich Syngas From Lignocellulosic Biomass Using Microwave-Assisted Pyrolysis Coupled With Activated Carbon Enabled Reforming.

Shi K, Yan J, Menéndez JA, Luo X, Yang G, Chen Y, Lester E, Wu T.

Front Chem. 2020 Jan 24;8:3. doi: 10.3389/fchem.2020.00003. eCollection 2020.


A Novel LncRNA, AC091729.7 Promotes Sinonasal Squamous Cell Carcinomas Proliferation and Invasion Through Binding SRSF2.

Yu B, Qu L, Wu T, Yan B, Kan X, Zhao X, Yang L, Li Y, Liu M, Tian L, Sun Y, Li Q.

Front Oncol. 2020 Jan 24;9:1575. doi: 10.3389/fonc.2019.01575. eCollection 2019.


Effect of Gene-Based Warfarin Dosing on Anticoagulation Control and Clinical Events in a Real-World Setting.

Zhang J, Wu T, Chen W, Fu J, Xia X, Chen L.

Front Pharmacol. 2020 Jan 17;10:1527. doi: 10.3389/fphar.2019.01527. eCollection 2019.


A review of implantable pulsatile blood pumps: Engineering perspectives.

Wu T, Khir AW, Kütting M, Du X, Lin H, Zhu Y, Hsu PL.

Int J Artif Organs. 2020 Feb 10:391398820902470. doi: 10.1177/0391398820902470. [Epub ahead of print]


TET2-mediated Cdkn2A DNA hydroxymethylation in midbrain dopaminergic neurons injury of Parkinson's disease.

Wu TT, Liu T, Li X, Chen YJ, Chen TJ, Zhu XY, Chen JL, Li Q, Liu Y, Feng Y, Wu YC.

Hum Mol Genet. 2020 Feb 10. pii: ddaa022. doi: 10.1093/hmg/ddaa022. [Epub ahead of print]


Diagnosing relapsing polychondritis remains a common challenge: experience from a Chinese retrospective cohort.

Zhang L, Wu TG, He YJ, Guo JY, Han LS, Lu JM, Liu SY, Li TF.

Clin Rheumatol. 2020 Feb 8. doi: 10.1007/s10067-019-04852-3. [Epub ahead of print]


Atorvastatin reduces cerebral vasospasm and infarction after aneurysmal subarachnoid hemorrhage in elderly Chinese adults.

Chen J, Li M, Zhu X, Chen L, Yang S, Zhang C, Wu T, Feng X, Wang Y, Chen Q.

Aging (Albany NY). 2020 Feb 7;12(3):2939-2951. doi: 10.18632/aging.102788. Epub 2020 Feb 7.


Quantitative synthetic MRI for evaluation of the lumbar intervertebral disk degeneration in patients with chronic low back pain.

Jiang Y, Yu L, Luo X, Lin Y, He B, Wu B, Qu J, Wu T, Pu-Yeh W, Zhang C, Li C, Chen M.

Eur J Radiol. 2020 Mar;124:108858. doi: 10.1016/j.ejrad.2020.108858. Epub 2020 Jan 29.


Impairment of Membrane Lipid Homeostasis by Bichalcone Analog TSWU-BR4 Attenuates Function of GRP78 in Regulation of the Oxidative Balance and Invasion of Cancer Cells.

Lee TL, Wang SG, Chan WL, Lee CH, Wu TS, Lin ML, Chen SS.

Cells. 2020 Feb 5;9(2). pii: E371. doi: 10.3390/cells9020371.


A Wide Dynamic Range Neural Data Acquisition System with High-Precision Delta-Sigma ADC and On-Chip EC-PC Spike Processor.

Xu J, Nguyen AT, Wu T, Zhao W, Luu DK, Yang Z.

IEEE Trans Biomed Circuits Syst. 2020 Feb 6. doi: 10.1109/TBCAS.2020.2972013. [Epub ahead of print]


Deep Multi-Scale Mesh Feature Learning for Automated Labeling of Raw Dental Surfaces from 3D Intraoral Scanners.

Lian C, Wang L, Wu TH, Wang F, Yap PT, Ko CC, Shen D.

IEEE Trans Med Imaging. 2020 Feb 5. doi: 10.1109/TMI.2020.2971730. [Epub ahead of print]


Corticosteroids do not influence the efficacy and kinetics of CAR-T cells for B-cell acute lymphoblastic leukemia.

Liu S, Deng B, Yin Z, Pan J, Lin Y, Ling Z, Wu T, Chen D, Chang AH, Gao Z, Song Y, Zhao Y, Tong C.

Blood Cancer J. 2020 Feb 6;10(2):15. doi: 10.1038/s41408-020-0280-y. No abstract available.


Investigation of Recessed Gate AlGaN/GaN MIS-HEMTs with Double AlGaN Barrier Designs toward an Enhancement-Mode Characteristic.

Wu TL, Tang SW, Jiang HJ.

Micromachines (Basel). 2020 Feb 3;11(2). pii: E163. doi: 10.3390/mi11020163.


Metabolic and Proteomic Perspectives of Augmentation of Nutritional Contents and Plant Defense in Vigna unguiculata.

Ahmad A, Khan TA, Mubeen S, Shahzadi I, Akram W, Saeed T, Bashir Z, Wang R, Alam M, Ahmed S, Hu D, Li G, Wu T.

Biomolecules. 2020 Feb 3;10(2). pii: E224. doi: 10.3390/biom10020224.


MdMYB8 is associated with flavonol biosynthesis via the activation of the MdFLS promoter in the fruits of Malus crabapple.

Li H, Li Y, Yu J, Wu T, Zhang J, Tian J, Yao Y.

Hortic Res. 2020 Feb 1;7:19. doi: 10.1038/s41438-020-0238-z. eCollection 2020.


Properties of Lightweight Aggregate Concrete Reinforced with Carbon and/or Polypropylene Fibers.

Wei H, Wu T, Yang X.

Materials (Basel). 2020 Jan 31;13(3). pii: E640. doi: 10.3390/ma13030640.


Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss.

Liu X, Simon JM, Xie H, Hu L, Wang J, Zurlo G, Fan C, Ptacek TS, Herring L, Tan X, Li M, Baldwin AS, Kim WY, Wu T, Kirschner MW, Gong K, Zhang Q.

Mol Cell. 2020 Jan 29. pii: S1097-2765(20)30009-5. doi: 10.1016/j.molcel.2020.01.009. [Epub ahead of print]


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