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White matter hyperintensity quantification in large-scale clinical acute ischemic stroke cohorts - The MRI-GENIE study.

Schirmer MD, Dalca AV, Sridharan R, Giese AK, Donahue KL, Nardin MJ, Mocking SJT, McIntosh EC, Frid P, Wasselius J, Cole JW, Holmegaard L, Jern C, Jimenez-Conde J, Lemmens R, Lindgren AG, Meschia JF, Roquer J, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Thijs V, Woo D, Vagal A, Xu H, Kittner SJ, McArdle PF, Mitchell BD, Rosand J, Worrall BB, Wu O, Golland P, Rost NS; MRI-GENIE Investigators.

Neuroimage Clin. 2019 May 29;23:101884. doi: 10.1016/j.nicl.2019.101884. [Epub ahead of print]


Learning functions in short-term cocaine users.

Kumar DS, Benedict E, Wu O, Rubin E, Gluck MA, Foltin RW, Myers CE, Vadhan NP.

Addict Behav Rep. 2019 Feb 8;9:100169. doi: 10.1016/j.abrep.2019.100169. eCollection 2019 Jun.


Big Data Approaches to Phenotyping Acute Ischemic Stroke Using Automated Lesion Segmentation of Multi-Center Magnetic Resonance Imaging Data.

Wu O, Winzeck S, Giese AK, Hancock BL, Etherton MR, Bouts MJRJ, Donahue K, Schirmer MD, Irie RE, Mocking SJT, McIntosh EC, Bezerra R, Kamnitsas K, Frid P, Wasselius J, Cole JW, Xu H, Holmegaard L, Jiménez-Conde J, Lemmens R, Lorentzen E, McArdle PF, Meschia JF, Roquer J, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Stanne TM, Thijs V, Vagal A, Woo D, Bevan S, Kittner SJ, Mitchell BD, Rosand J, Worrall BB, Jern C, Lindgren AG, Maguire J, Rost NS; MRI-GENIE and GISCOME Investigators.

Stroke. 2019 Jun 10:STROKEAHA119025373. doi: 10.1161/STROKEAHA.119.025373. [Epub ahead of print]


Ensemble of Convolutional Neural Networks Improves Automated Segmentation of Acute Ischemic Lesions Using Multiparametric Diffusion-Weighted MRI.

Winzeck S, Mocking SJT, Bezerra R, Bouts MJRJ, McIntosh EC, Diwan I, Garg P, Chutinet A, Kimberly WT, Copen WA, Schaefer PW, Ay H, Singhal AB, Kamnitsas K, Glocker B, Sorensen AG, Wu O.

AJNR Am J Neuroradiol. 2019 Jun;40(6):938-945. doi: 10.3174/ajnr.A6077. Epub 2019 May 30.


Mechanical and biological evaluations of novel electrospun PLLA composite scaffolds doped with oxide ceramics.

Chan K, Tsoi JK, Wu OK, Yon MJ, Wong RW.

J Mech Behav Biomed Mater. 2019 May 16;97:229-237. doi: 10.1016/j.jmbbm.2019.05.024. [Epub ahead of print]


Economic evaluation of a phase III international randomised controlled trial of very early mobilisation after stroke (AVERT).

Gao L, Sheppard L, Wu O, Churilov L, Mohebbi M, Collier J, Bernhardt J, Ellery F, Dewey H, Moodie M; AVERT Trial Collaboration Group.

BMJ Open. 2019 May 22;9(5):e026230. doi: 10.1136/bmjopen-2018-026230.


Traumatic Microbleeds in the Hippocampus and Corpus Callosum Predict Duration of Posttraumatic Amnesia.

Mazwi NL, Izzy S, Tan CO, Martinez S, Glenn MB, Giacino JT, Wu O, Zafonte R, Edlow BL.

J Head Trauma Rehabil. 2019 May 16. doi: 10.1097/HTR.0000000000000479. [Epub ahead of print]


Spatial Signature of White Matter Hyperintensities in Stroke Patients.

Schirmer MD, Giese AK, Fotiadis P, Etherton MR, Cloonan L, Viswanathan A, Greenberg SM, Wu O, Rost NS.

Front Neurol. 2019 Mar 19;10:208. doi: 10.3389/fneur.2019.00208. eCollection 2019.


Reduced Ischemic Lesion Growth with Heparin in Acute Ischemic Stroke.

Rocha EA, Ji R, Ay H, Li Z, Arsava EM, Silva GS, Sorensen AG, Wu O, Singhal AB.

J Stroke Cerebrovasc Dis. 2019 Jun;28(6):1500-1508. doi: 10.1016/j.jstrokecerebrovasdis.2019.03.016. Epub 2019 Mar 29.


Meta-analysis of real-world evidence comparing non-vitamin K antagonist oral anticoagulants with vitamin K antagonists for the treatment of patients with non-valvular atrial fibrillation.

Coleman CI, Briere JB, Fauchier L, Levy P, Bowrin K, Toumi M, Millier A, Taieb V, Wu O.

J Mark Access Health Policy. 2019 Feb 4;7(1):1574541. doi: 10.1080/20016689.2019.1574541. eCollection 2019.


White Matter Integrity and Early Outcomes After Acute Ischemic Stroke.

Etherton MR, Wu O, Giese AK, Lauer A, Boulouis G, Mills B, Cloonan L, Donahue KL, Copen W, Schaefer P, Rost NS.

Transl Stroke Res. 2019 Jan 28. doi: 10.1007/s12975-019-0689-4. [Epub ahead of print]


Correction to: Real-World Safety of Intravitreal Bevacizumab and Ranibizumab Treatments for Retinal Diseases in Thailand: A Prospective Observational Study.

Sangroongruangsri S, Chaikledkaew U, Kumluang S, Wu O, Geue C, Ratanapakorn T, Leelahavarong P, Ingsrisawang L, Ruamviboonsuk P, Taweebanjongsin W, Choovuthayakorn J, Singalavanija A, Hanutsaha P, Kulvichit K, Ratanapojnard T, Wongsawad W, Teerawattananon Y.

Clin Drug Investig. 2019 Jan;39(1):115. doi: 10.1007/s40261-019-00747-y.


Repeated recurrence of thoracic spine stenosis following decompression alone for ossification of the ligamentum flavum: case report.

Barath AS, Wu OC, Patel M, Kasliwal MK.

J Neurosurg Spine. 2018 Dec 7;30(3):332-336. doi: 10.3171/2018.8.SPINE18517.


Images in neuroscience: Cervical bony lesion.

Wu OC, Atli K, Kasliwal MK.

J Clin Neurosci. 2018 Oct 26. pii: S0967-5868(18)30858-0. doi: 10.1016/j.jocn.2018.10.061. [Epub ahead of print] No abstract available.


Calcified stylohyoid ligament: A rare presentation as a thick cord-like structure during anterior cervical discectomy and fusion.

Wu OC, Barath AS, Kasliwal MK.

Neurol India. 2018 Nov-Dec;66(6):1850-1851. doi: 10.4103/0028-3886.246265. No abstract available.


Brazilian Analytical Decision Model for Cardiovascular Disease: An Adaptation of the Scottish Cardiovascular Disease Policy Model.

Riveros BS, Torelli Reis WC, Lucchetta RC, Moreira LB, Lewsey J, Correr CJ, Wu O.

Value Health Reg Issues. 2018 Dec;17:210-216. doi: 10.1016/j.vhri.2018.01.002. Epub 2018 Nov 28.


Web-based physiotherapy for people affected by multiple sclerosis: a single blind, randomized controlled feasibility study.

Paul L, Renfrew L, Freeman J, Murray H, Weller B, Mattison P, McConnachie A, Heggie R, Wu O, Coulter EH.

Clin Rehabil. 2019 Mar;33(3):473-484. doi: 10.1177/0269215518817080. Epub 2018 Dec 4.


Comparative safety and effectiveness of direct oral anticoagulants in patients with atrial fibrillation in clinical practice in Scotland.

Mueller T, Alvarez-Madrazo S, Robertson C, Wu O, Bennie M.

Br J Clin Pharmacol. 2019 Feb;85(2):422-431. doi: 10.1111/bcp.13814. Epub 2018 Dec 18.


Real-world clinical evidence on rivaroxaban, dabigatran, and apixaban compared with vitamin K antagonists in patients with nonvalvular atrial fibrillation: a systematic literature review.

Briere JB, Bowrin K, Coleman C, Fauchier L, Levy P, Folkerts K, Toumi M, Taieb V, Millier A, Wu O.

Expert Rev Pharmacoecon Outcomes Res. 2019 Feb;19(1):27-36. doi: 10.1080/14737167.2018.1518134. Epub 2018 Sep 19. Erratum in: Expert Rev Pharmacoecon Outcomes Res. 2019 Jun 20;:1.


Comparative efficacy of bevacizumab, ranibizumab, and aflibercept for treatment of macular edema secondary to retinal vein occlusion: a systematic review and network meta-analysis.

Sangroongruangsri S, Ratanapakorn T, Wu O, Anothaisintawee T, Chaikledkaew U.

Expert Rev Clin Pharmacol. 2018 Sep;11(9):903-916. doi: 10.1080/17512433.2018.1507735. Epub 2018 Aug 10. Review.


Real-World Safety of Intravitreal Bevacizumab and Ranibizumab Treatments for Retinal Diseases in Thailand: A Prospective Observational Study.

Sangroongruangsri S, Chaikledkaew U, Kumluang S, Wu O, Geue C, Ratanapakorn T, Leelahavarong P, Ingsrisawang L, Ruamviboonsuk P, Taweebanjongsin W, Choovuthayakorn J, Singalavanija A, Hanutsaha P, Kulvichit K, Ratanapojnard T, Wongsawad W, Teerawattananon Y.

Clin Drug Investig. 2018 Sep;38(9):853-865. doi: 10.1007/s40261-018-0678-5. Erratum in: Clin Drug Investig. 2019 Jan 19;:.


Commentary: Extended Asymmetrical Pedicle Subtraction Osteotomy for Adult Spinal Deformity: 3-Dimensional Operative Video.

Wu OC, Kasliwal MK.

Oper Neurosurg (Hagerstown). 2019 Feb 1;16(2):54. doi: 10.1093/ons/opy172. No abstract available.


Identifying therapeutic targets from spontaneous beneficial brain lesions.

Joutsa J, Shih LC, Horn A, Reich MM, Wu O, Rost NS, Fox MD.

Ann Neurol. 2018 Jul;84(1):153-157. doi: 10.1002/ana.25285.


Commentary: Mean 6-Year Follow-up of Magnetically Controlled Growing Rod Patients With Early Onset Scoliosis: A Glimpse of What Happens to Graduates.

Wu OC, Kasliwal MK.

Neurosurgery. 2019 May 1;84(5):E266. doi: 10.1093/neuros/nyy282. No abstract available.


Resection of 2 Intradural Extramedullary Cervical Spine Tumors in a Patient With Neurofibromatosis Type 2: 3-Dimensional Operative Video.

Dekker SE, Glenn CA, Ostergard TA, Wu OC, Alonso F, Pace JA, Rothstein BD, Ray A, Bambakidis NC.

Oper Neurosurg (Hagerstown). 2019 Feb 1;16(2):274. doi: 10.1093/ons/opy149.


Functional networks reemerge during recovery of consciousness after acute severe traumatic brain injury.

Threlkeld ZD, Bodien YG, Rosenthal ES, Giacino JT, Nieto-Castanon A, Wu O, Whitfield-Gabrieli S, Edlow BL.

Cortex. 2018 Sep;106:299-308. doi: 10.1016/j.cortex.2018.05.004. Epub 2018 May 12.


Neuroimaging Paradigms to Identify Patients for Reperfusion Therapy in Stroke of Unknown Onset.

Etherton MR, Barreto AD, Schwamm LH, Wu O.

Front Neurol. 2018 May 15;9:327. doi: 10.3389/fneur.2018.00327. eCollection 2018. Review.


Impact of Lesion Load Thresholds on Alberta Stroke Program Early Computed Tomographic Score in Diffusion-Weighted Imaging.

Schröder J, Cheng B, Malherbe C, Ebinger M, Köhrmann M, Wu O, Kang DW, Liebeskind DS, Tourdias T, Singer OC, Campbell B, Luby M, Warach S, Fiehler J, Kemmling A, Fiebach JB, Gerloff C, Thomalla G.

Front Neurol. 2018 Apr 23;9:273. doi: 10.3389/fneur.2018.00273. eCollection 2018.


Beyond Lesion Volumes: Network-based Approach for the Investigation of Neurocognitive Deficits in Patients with Chronic Subcortical Strokes.

Wu O.

Radiology. 2018 Jul;288(1):195-197. doi: 10.1148/radiol.2018180382. Epub 2018 May 8. No abstract available.


Letter to the Editor. Radiographic differentiation of idiopathic spinal cord herniation versus dorsal arachnoid webs.

Wu OC, Kasliwal MK.

J Neurosurg Spine. 2018 Jul;29(1):120-121. doi: 10.3171/2017.11.SPINE171194. Epub 2018 Apr 27. No abstract available.


Intravenous thrombolysis in unwitnessed stroke onset: MR WITNESS trial results.

Schwamm LH, Wu O, Song SS, Latour LL, Ford AL, Hsia AW, Muzikansky A, Betensky RA, Yoo AJ, Lev MH, Boulouis G, Lauer A, Cougo P, Copen WA, Harris GJ, Warach S; MR WITNESS Investigators.

Ann Neurol. 2018 May;83(5):980-993. doi: 10.1002/ana.25235. Epub 2018 Apr 27.


Wrap-Around Appearance: Underrecognized Radiologic Feature of Spinal Lymphoma.

Patel M, Wu OC, Kasliwal MK.

World Neurosurg. 2018 Jul;115:157-158. doi: 10.1016/j.wneu.2018.04.051. Epub 2018 Apr 17.


Protocol for a systematic review and thematic synthesis of patient experiences of central venous access devices in anti-cancer treatment.

Ryan C, Hesselgreaves H, Wu O, Paul J, Dixon-Hughes J, Moss JG.

Syst Rev. 2018 Apr 18;7(1):61. doi: 10.1186/s13643-018-0721-x.


Stroke care in Africa: A systematic review of the literature.

Urimubenshi G, Cadilhac DA, Kagwiza JN, Wu O, Langhorne P.

Int J Stroke. 2018 Oct;13(8):797-805. doi: 10.1177/1747493018772747. Epub 2018 Apr 17.


A systematic review of hepatitis B screening economic evaluations in low- and middle-income countries.

Wright CM, Boudarène L, Ha NT, Wu O, Hawkins N.

BMC Public Health. 2018 Mar 20;18(1):373. doi: 10.1186/s12889-018-5261-8. Review.


Implications of dietary ω-3 and ω-6 polyunsaturated fatty acids in breast cancer.

Zanoaga O, Jurj A, Raduly L, Cojocneanu-Petric R, Fuentes-Mattei E, Wu O, Braicu C, Gherman CD, Berindan-Neagoe I.

Exp Ther Med. 2018 Feb;15(2):1167-1176. doi: 10.3892/etm.2017.5515. Epub 2017 Nov 16.


Multimodal Characterization of the Late Effects of Traumatic Brain Injury: A Methodological Overview of the Late Effects of Traumatic Brain Injury Project.

Edlow BL, Keene CD, Perl DP, Iacono D, Folkerth RD, Stewart W, Mac Donald CL, Augustinack J, Diaz-Arrastia R, Estrada C, Flannery E, Gordon WA, Grabowski TJ, Hansen K, Hoffman J, Kroenke C, Larson EB, Lee P, Mareyam A, McNab JA, McPhee J, Moreau AL, Renz A, Richmire K, Stevens A, Tang CY, Tirrell LS, Trittschuh EH, van der Kouwe A, Varjabedian A, Wald LL, Wu O, Yendiki A, Young L, Zöllei L, Fischl B, Crane PK, Dams-O'Connor K.

J Neurotrauma. 2018 Jul 15;35(14):1604-1619. doi: 10.1089/neu.2017.5457. Epub 2018 May 3.


Oxidative Stress Biomarkers of Brain Damage: Hyperacute Plasma F2-Isoprostane Predicts Infarct Growth in Stroke.

Lorenzano S, Rost NS, Khan M, Li H, Lima FO, Maas MB, Green RE, Thankachan TK, Dipietro AJ, Arai K, Som AT, Pham LD, Wu O, Harris GJ, Lo EH, Blumberg JB, Milbury PE, Feske SK, Furie KL.

Stroke. 2018 Mar;49(3):630-637. doi: 10.1161/STROKEAHA.117.018440. Epub 2018 Jan 25.


Acute Ischemic Pediatric Stroke Management: An Extended Window for Mechanical Thrombectomy?

Kulhari A, Dorn E, Pace J, Alambyan V, Chen S, Wu OC, Rizvi M, Hammond A, Ramos-Estebanez C.

Front Neurol. 2017 Nov 29;8:634. doi: 10.3389/fneur.2017.00634. eCollection 2017.


In patients with suspected acute stroke, CT perfusion-based cerebral blood flow maps cannot substitute for DWI in measuring the ischemic core.

Copen WA, Yoo AJ, Rost NS, Morais LT, Schaefer PW, González RG, Wu O.

PLoS One. 2017 Nov 30;12(11):e0188891. doi: 10.1371/journal.pone.0188891. eCollection 2017.


Association between patient outcomes and key performance indicators of stroke care quality: A systematic review and meta-analysis.

Urimubenshi G, Langhorne P, Cadilhac DA, Kagwiza JN, Wu O.

Eur Stroke J. 2017 Dec;2(4):287-307. doi: 10.1177/2396987317735426. Epub 2017 Oct 5. Review.


Structural Integrity of Normal Appearing White Matter and Sex-Specific Outcomes After Acute Ischemic Stroke.

Etherton MR, Wu O, Cougo P, Giese AK, Cloonan L, Fitzpatrick KM, Kanakis AS, Boulouis G, Karadeli HH, Lauer A, Rosand J, Furie KL, Rost NS.

Stroke. 2017 Dec;48(12):3387-3389. doi: 10.1161/STROKEAHA.117.019258. Epub 2017 Nov 10.


A comparative research on obesity hypertension by the comparisons and associations between waist circumference, body mass index with systolic and diastolic blood pressure, and the clinical laboratory data between four special Chinese adult groups.

Wu O, Leng JH, Yang FF, Yang HM, Zhang H, Li ZF, Zhang XY, Yuan CD, Li JJ, Pan Q, Liu W, Ren YJ, Liu B, Liu QM, Cao CJ.

Clin Exp Hypertens. 2018;40(1):16-21. doi: 10.1080/10641963.2017.1281940. Epub 2017 Oct 30.


Early detection of consciousness in patients with acute severe traumatic brain injury.

Edlow BL, Chatelle C, Spencer CA, Chu CJ, Bodien YG, O'Connor KL, Hirschberg RE, Hochberg LR, Giacino JT, Rosenthal ES, Wu O.

Brain. 2017 Sep 1;140(9):2399-2414. doi: 10.1093/brain/awx176.


A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial.

Langhorne P, Wu O, Rodgers H, Ashburn A, Bernhardt J.

Health Technol Assess. 2017 Sep;21(54):1-120. doi: 10.3310/hta21540.


Design and rationale for examining neuroimaging genetics in ischemic stroke: The MRI-GENIE study.

Giese AK, Schirmer MD, Donahue KL, Cloonan L, Irie R, Winzeck S, Bouts MJRJ, McIntosh EC, Mocking SJ, Dalca AV, Sridharan R, Xu H, Frid P, Giralt-Steinhauer E, Holmegaard L, Roquer J, Wasselius J, Cole JW, McArdle PF, Broderick JP, Jimenez-Conde J, Jern C, Kissela BM, Kleindorfer DO, Lemmens R, Lindgren A, Meschia JF, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Thijs V, Woo D, Worrall BB, Kittner SJ, Mitchell BD, Rosand J, Golland P, Wu O, Rost NS.

Neurol Genet. 2017 Aug 24;3(5):e180. doi: 10.1212/NXG.0000000000000180. eCollection 2017 Oct.


Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease.

Donahue MJ, Achten E, Cogswell PM, De Leeuw FE, Derdeyn CP, Dijkhuizen RM, Fan AP, Ghaznawi R, Heit JJ, Ikram MA, Jezzard P, Jordan LC, Jouvent E, Knutsson L, Leigh R, Liebeskind DS, Lin W, Okell TW, Qureshi AI, Stagg CJ, van Osch MJ, van Zijl PC, Watchmaker JM, Wintermark M, Wu O, Zaharchuk G, Zhou J, Hendrikse J.

J Cereb Blood Flow Metab. 2018 Sep;38(9):1391-1417. doi: 10.1177/0271678X17721830. Epub 2017 Aug 17.


Towards a Transparent, Credible, Evidence-Based Decision-Making Process of New Drug Listing on the Hong Kong Hospital Authority Drug Formulary: Challenges and Suggestions.

Wong CKH, Wu O, Cheung BMY.

Appl Health Econ Health Policy. 2018 Feb;16(1):5-14. doi: 10.1007/s40258-017-0339-5.


Diffuse microvascular dysfunction and loss of white matter integrity predict poor outcomes in patients with acute ischemic stroke.

Rost NS, Cougo P, Lorenzano S, Li H, Cloonan L, Bouts MJ, Lauer A, Etherton MR, Karadeli HH, Musolino PL, Copen WA, Arai K, Lo EH, Feske SK, Furie KL, Wu O.

J Cereb Blood Flow Metab. 2018 Jan;38(1):75-86. doi: 10.1177/0271678X17706449. Epub 2017 May 8.


Revisiting Grade 3 Diffuse Axonal Injury: Not All Brainstem Microbleeds are Prognostically Equal.

Izzy S, Mazwi NL, Martinez S, Spencer CA, Klein JP, Parikh G, Glenn MB, Greenberg SM, Greer DM, Wu O, Edlow BL.

Neurocrit Care. 2017 Oct;27(2):199-207. doi: 10.1007/s12028-017-0399-2.

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