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Pharmacometabolomics of Bronchodilator Response in Asthma and the Role of Age-Metabolite Interactions.

Kelly RS, Sordillo JE, Lutz SM, Avila L, Soto-Quiros M, Celedón JC, McGeachie MJ, Dahlin A, Tantisira K, Huang M, Clish CB, Weiss ST, Lasky-Su J, Wu AC.

Metabolites. 2019 Sep 7;9(9). pii: E179. doi: 10.3390/metabo9090179.


Analysis of risk factors for postoperative recurrence of thyroid cancer.


J BUON. 2019 Mar-Apr;24(2):813-818.


Transcribe this way: Rap1 confers promoter directionality by repressing divergent transcription.

Wu ACK, Van Werven FJ.

Transcription. 2019 Jun;10(3):164-170. doi: 10.1080/21541264.2019.1608716. Epub 2019 May 5. Review.


A Group Visit for High-Risk Pediatric Asthma Patients: A Quality Improvement Initiative to Improve Asthma Care.

Fallon M, Haynes L, Cadet T, Petrosino S, Cazeau E, Solis J, Cox J, Wu AC, Holder-Niles FF.

Clin Pediatr (Phila). 2019 Jun;58(7):746-751. doi: 10.1177/0009922819839238. Epub 2019 Apr 2.


Reply to Mahler: Peak Inspiratory Flow Rate: An Emerging Biomarker in Chronic Obstructive Pulmonary Disease.

Wu AC, Himes BE.

Am J Respir Crit Care Med. 2019 Jun 15;199(12):1579. doi: 10.1164/rccm.201902-0432LE. No abstract available.


Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement.

Wu AC, Kiley JP, Noel PJ, Amur S, Burchard EG, Clancy JP, Galanter J, Inada M, Jones TK, Kropski JA, Loyd JE, Nogee LM, Raby BA, Rogers AJ, Schwartz DA, Sin DD, Spira A, Weiss ST, Young LR, Himes BE.

Am J Respir Crit Care Med. 2018 Dec 15;198(12):e116-e136. doi: 10.1164/rccm.201810-1895ST.


Is Telemedicine as Effective as Usual Care?

Portnoy JM, Wu AC.

J Allergy Clin Immunol Pract. 2019 Jan;7(1):217-218. doi: 10.1016/j.jaip.2018.09.002. No abstract available.


Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype.

Sordillo JE, McGeachie M, Lutz SM, Lasky-Su J, Tantisira K, Tsai CH, Dahlin A, Kelly R, Wu AC.

Pediatr Pulmonol. 2019 Feb;54(2):158-164. doi: 10.1002/ppul.24219. Epub 2018 Dec 25.


Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults.

Dahlin A, Sordillo JE, Ziniti J, Iribarren C, Lu M, Weiss ST, Tantisira KG, Lu Q, Kan M, Himes BE, Jorgenson E, Wu AC.

J Allergy Clin Immunol. 2019 Apr;143(4):1633-1635. doi: 10.1016/j.jaci.2018.11.037. Epub 2018 Dec 20. No abstract available.


Repression of Divergent Noncoding Transcription by a Sequence-Specific Transcription Factor.

Wu ACK, Patel H, Chia M, Moretto F, Frith D, Snijders AP, van Werven FJ.

Mol Cell. 2018 Dec 20;72(6):942-954.e7. doi: 10.1016/j.molcel.2018.10.018.


Correlation over time of toenail metals among participants in the VA normative aging study from 1992 to 2014.

Wu AC, Allen JG, Coull B, Amarasiriwardena C, Sparrow D, Vokonas P, Schwartz J, Weisskopf MG.

J Expo Sci Environ Epidemiol. 2019 Sep;29(5):663-673. doi: 10.1038/s41370-018-0095-0. Epub 2018 Nov 27.


Increasing trends of anaphylaxis-related events: an analysis of anaphylaxis using nationwide data in Taiwan, 2001-2013.

Yao TC, Wu AC, Huang YW, Wang JY, Tsai HJ.

World Allergy Organ J. 2018 Oct 10;11(1):23. doi: 10.1186/s40413-018-0202-7. eCollection 2018.


The Implementation Process for Pharmacogenomic Testing for Cancer-Targeted Therapies.

Wu AC, Mazor KM, Ceccarelli R, Loomer S, Lu CY.

J Pers Med. 2018 Oct 1;8(4). pii: E32. doi: 10.3390/jpm8040032.


Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment.

Kaur S, Raggatt LJ, Millard SM, Wu AC, Batoon L, Jacobsen RN, Winkler IG, MacDonald KP, Perkins AC, Hume DA, Levesque JP, Pettit AR.

Blood. 2018 Aug 16;132(7):735-749. doi: 10.1182/blood-2018-01-829663. Epub 2018 Jun 26.


Plasma metabolite profiles in children with current asthma.

Kelly RS, Sordillo JE, Lasky-Su J, Dahlin A, Perng W, Rifas-Shiman SL, Weiss ST, Gold DR, Litonjua AA, Hivert MF, Oken E, Wu AC.

Clin Exp Allergy. 2018 Oct;48(10):1297-1304. doi: 10.1111/cea.13183. Epub 2018 Jul 3.


Insurance Coverage Policies for Pharmacogenomic and Multi-Gene Testing for Cancer.

Lu CY, Loomer S, Ceccarelli R, Mazor KM, Sabin J, Clayton EW, Ginsburg GS, Wu AC.

J Pers Med. 2018 May 16;8(2). pii: E19. doi: 10.3390/jpm8020019.


Asthma: Overdiagnosed, Underdiagnosed, and Ineffectively Treated.

Wu AC, Greenberger PA.

J Allergy Clin Immunol Pract. 2018 May - Jun;6(3):801-802. doi: 10.1016/j.jaip.2018.02.023. No abstract available.


Seeing Floaters: A Case Report and Literature Review of Intraventricular Migration of Silicone Oil Tamponade Material for Retinal Detachment.

Potts MB, Wu AC, Rusinak DJ, Kesavabhotla K, Jahromi BS.

World Neurosurg. 2018 Jul;115:201-205. doi: 10.1016/j.wneu.2018.04.049. Epub 2018 Apr 17. Review.


Epileptiform activity in traumatic brain injury predicts post-traumatic epilepsy.

Kim JA, Boyle EJ, Wu AC, Cole AJ, Staley KJ, Zafar S, Cash SS, Westover MB.

Ann Neurol. 2018 Apr;83(4):858-862. doi: 10.1002/ana.25211. Epub 2018 Apr 10.


Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.

Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton TJ, Nguyen TA, Torgerson DG, Kwok PY, Levin AM, Celedón JC, Forno E, Hakonarson H, Sleiman PM, Dahlin A, Tantisira KG, Weiss ST, Serebrisky D, Brigino-Buenaventura E, Farber HJ, Meade K, Lenoir MA, Avila PC, Sen S, Thyne SM, Rodriguez-Cintron W, Winkler CA, Moreno-Estrada A, Sandoval K, Rodriguez-Santana JR, Kumar R, Williams LK, Ahituv N, Ziv E, Seibold MA, Darnell RB, Zaitlen N, Hernandez RD, Burchard EG; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium.

Am J Respir Crit Care Med. 2018 Jun 15;197(12):1552-1564. doi: 10.1164/rccm.201712-2529OC.


Quantifying the Polygenic Contribution to Cutaneous Squamous Cell Carcinoma Risk.

Sordillo JE, Kraft P, Wu AC, Asgari MM.

J Invest Dermatol. 2018 Jul;138(7):1507-1510. doi: 10.1016/j.jid.2018.01.031. Epub 2018 Feb 13. Erratum in: J Invest Dermatol. 2019 Apr;139(4):977.


Increased Dose and Duration of Statin Use Is Associated with Decreased Asthma-Related Emergency Department Visits and Hospitalizations.

Wang JY, Yao TC, Tsai YT, Wu AC, Tsai HJ.

J Allergy Clin Immunol Pract. 2018 Sep - Oct;6(5):1588-1595.e1. doi: 10.1016/j.jaip.2017.12.017. Epub 2018 Feb 6.


Systems biology and in vitro validation identifies family with sequence similarity 129 member A (FAM129A) as an asthma steroid response modulator.

McGeachie MJ, Clemmer GL, Hayete B, Xing H, Runge K, Wu AC, Jiang X, Lu Q, Church B, Khalil I, Tantisira K, Weiss S.

J Allergy Clin Immunol. 2018 Nov;142(5):1479-1488.e12. doi: 10.1016/j.jaci.2017.11.059. Epub 2018 Mar 2.


A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.

Panganiban RA, Sun M, Dahlin A, Park HR, Kan M, Himes BE, Mitchel JA, Iribarren C, Jorgenson E, Randell SH, Israel E, Tantisira K, Shore S, Park JA, Weiss ST, Wu AC, Lu Q.

J Allergy Clin Immunol. 2018 Nov;142(5):1469-1478.e2. doi: 10.1016/j.jaci.2017.11.040. Epub 2018 Jan 9.


Social Media and the Allergist: Evidence Supports Increasing Our Engagement.

Nickels AS, Wu AC, Stukus DR.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):313-314. doi: 10.1016/j.jaip.2017.09.007. No abstract available.


The phosphatidylinositide 3-kinase (PI3K) signaling pathway is a determinant of zileuton response in adults with asthma.

Dahlin A, Qiu W, Litonjua AA, Lima JJ, Tamari M, Kubo M, Irvin CG, Peters SP, Wu AC, Weiss ST, Tantisira KG.

Pharmacogenomics J. 2018 Sep;18(5):665-677. doi: 10.1038/s41397-017-0006-0. Epub 2018 Jan 3.


Pigment epithelium-derived factor short peptides facilitate full-thickness cutaneous wound healing by promoting epithelial basal cell and hair follicle stem cell proliferation.

Tsai SH, Tsao LP, Chang SH, Ho TC, Tung KY, Wu AC, Tsao YP.

Exp Ther Med. 2017 Nov;14(5):4853-4861. doi: 10.3892/etm.2017.5134. Epub 2017 Sep 19.


Correction to: Airplane pilot mental health and suicidal thoughts: a cross-sectional descriptive study via anonymous web-based survey.

Wu AC, Donnelly-McLay D, Weisskopf MG, McNeely E, Betancourt TS, Allen JG.

Environ Health. 2017 Nov 27;16(1):129. doi: 10.1186/s12940-017-0341-2.


Access to Guideline-Recommended Pharmacogenomic Tests for Cancer Treatments: Experience of Providers and Patients.

Wu AC, Mazor KM, Ceccarelli R, Loomer S, Lu CY.

J Pers Med. 2017 Nov 15;7(4). pii: E17. doi: 10.3390/jpm7040017.


CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair.

Batoon L, Millard SM, Wullschleger ME, Preda C, Wu AC, Kaur S, Tseng HW, Hume DA, Levesque JP, Raggatt LJ, Pettit AR.

Biomaterials. 2019 Mar;196:51-66. doi: 10.1016/j.biomaterials.2017.10.033. Epub 2017 Oct 22.


Trends in health care utilization for asthma exacerbations among diverse populations with asthma in the United States.

Stone C, Gebretsadik T, Lee RL, Evans AM, Hartert TV, Mitchel E, Morrow J, Wu AC, Iribarren C, Butler MG, Larkin EK, Turi KN, Wu P.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):295-297.e5. doi: 10.1016/j.jaip.2017.07.038. Epub 2017 Sep 19. No abstract available.


The impact of FDA regulatory activities on incident dispensing of LABA-containing medication: 2005-2011.

Baker MA, Butler MG, Seymour S, Zhang F, Wu Y, Wu AC, Levenson MS, Wu P, Iyer A, Toh S, Iyasu S, Zhou EH.

J Asthma. 2018 Aug;55(8):907-914. doi: 10.1080/02770903.2017.1378355. Epub 2017 Oct 13.


Seasonal patterns of Asthma medication fills among diverse populations of the United States.

Turi KN, Gebretsadik T, Lee RL, Hartert TV, Evans AM, Stone C, Sicignano NM, Wu AC, Iribarren C, Butler MG, Mitchel E, Morrow J, Larkin EK, Wu P.

J Asthma. 2018 Jul;55(7):764-770. doi: 10.1080/02770903.2017.1362426. Epub 2017 Sep 7.


Improved Gene Transfer with Functionalized Hollow Mesoporous Silica Nanoparticles of Reduced Cytotoxicity.

Zhan Z, Zhang X, Huang J, Huang Y, Huang Z, Pan X, Quan G, Liu H, Wang L, Wu AC.

Materials (Basel). 2017 Jun 30;10(7). pii: E731. doi: 10.3390/ma10070731.


Racial disparities in family-provider interactions for pediatric asthma care.

Trivedi M, Fung V, Kharbanda EO, Larkin EK, Butler MG, Horan K, Lieu TA, Wu AC.

J Asthma. 2018 Apr;55(4):424-429. doi: 10.1080/02770903.2017.1337790. Epub 2017 Jul 14.


Integration of metabolomic and transcriptomic networks in pregnant women reveals biological pathways and predictive signatures associated with preeclampsia.

Kelly RS, Croteau-Chonka DC, Dahlin A, Mirzakhani H, Wu AC, Wan ES, McGeachie MJ, Qiu W, Sordillo JE, Al-Garawi A, Gray KJ, McElrath TF, Carey VJ, Clish CB, Litonjua AA, Weiss ST, Lasky-Su JA.

Metabolomics. 2017 Jan;13(1). pii: 7. doi: 10.1007/s11306-016-1149-8. Epub 2016 Dec 12.


Coordinated Asthma Program Improves Asthma Outcomes in High-Risk Children.

Holder-Niles F, Haynes L, D'Couto H, Hehn RS, Graham DA, Wu AC, Cox JE.

Clin Pediatr (Phila). 2017 Sep;56(10):934-941. doi: 10.1177/0009922817705186. Epub 2017 Apr 24.


Airplane pilot mental health and suicidal thoughts: a cross-sectional descriptive study via anonymous web-based survey.

Wu AC, Donnelly-McLay D, Weisskopf MG, McNeely E, Betancourt TS, Allen JG.

Environ Health. 2016 Dec 15;15(1):121. doi: 10.1186/s12940-016-0200-6. Erratum in: Environ Health. 2017 Nov 27;16(1):129.


Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury.

Chuang JY, Kao TJ, Lin SH, Wu AC, Lee PT, Su TP, Yeh SH, Lee YC, Wu CC, Chang WC.

Redox Biol. 2017 Apr;11:135-143. doi: 10.1016/j.redox.2016.11.012. Epub 2016 Nov 29.


Impact of Copayment Changes on Children's Albuterol Inhaler Use and Costs after the Clean Air Act Chlorofluorocarbon Ban.

Galbraith AA, Fung V, Li L, Butler MG, Nordin JD, Hsu J, Smith D, Vollmer WM, Lieu TA, Soumerai SB, Wu AC.

Health Serv Res. 2018 Feb;53(1):156-174. doi: 10.1111/1475-6773.12615. Epub 2016 Nov 20.


Asthma Metabolomics and the Potential for Integrative Omics in Research and the Clinic.

Kelly RS, Dahlin A, McGeachie MJ, Qiu W, Sordillo J, Wan ES, Wu AC, Lasky-Su J.

Chest. 2017 Feb;151(2):262-277. doi: 10.1016/j.chest.2016.10.008. Epub 2016 Oct 21. Review.


The Promise of Improving Asthma Control Using Mobile Health.

Wu AC.

J Allergy Clin Immunol Pract. 2016 Jul-Aug;4(4):738-9. doi: 10.1016/j.jaip.2016.04.003. No abstract available.


Mismatching Among Guidelines, Providers, and Parents on Controller Medication Use in Children with Asthma.

Wu AC, Li L, Fung V, Kharbanda EO, Larkin EK, Butler MG, Galbraith A, Miroshnik I, Davis RL, Horan K, Lieu TA.

J Allergy Clin Immunol Pract. 2016 Sep-Oct;4(5):910-6. doi: 10.1016/j.jaip.2016.04.004. Epub 2016 May 17.


CD169(+) macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer.

Wu AC, He Y, Broomfield A, Paatan NJ, Harrington BS, Tseng HW, Beaven EA, Kiernan DM, Swindle P, Clubb AB, Levesque JP, Winkler IG, Ling MT, Srinivasan B, Hooper JD, Pettit AR.

J Pathol. 2016 Jun;239(2):218-30. doi: 10.1002/path.4718. Epub 2016 Apr 27.


Erratum to: 'Aro: a machine learning approach to identifying single molecules and estimating classification error in fluorescence microscopy images'.

Wu AC, Rifkin SA.

BMC Bioinformatics. 2016 May 9;17:207. doi: 10.1186/s12859-016-1049-y. No abstract available.


Effect of Prenatal Supplementation With Vitamin D on Asthma or Recurrent Wheezing in Offspring by Age 3 Years: The VDAART Randomized Clinical Trial.

Litonjua AA, Carey VJ, Laranjo N, Harshfield BJ, McElrath TF, O'Connor GT, Sandel M, Iverson RE Jr, Lee-Paritz A, Strunk RC, Bacharier LB, Macones GA, Zeiger RS, Schatz M, Hollis BW, Hornsby E, Hawrylowicz C, Wu AC, Weiss ST.

JAMA. 2016 Jan 26;315(4):362-70. doi: 10.1001/jama.2015.18589.


CMTR1 is associated with increased asthma exacerbations in patients taking inhaled corticosteroids.

Dahlin A, Denny J, Roden DM, Brilliant MH, Ingram C, Kitchner TE, Linneman JG, Shaffer CM, Weeke P, Xu H, Kubo M, Tamari M, Clemmer GL, Ziniti J, McGeachie MJ, Tantisira KG, Weiss ST, Wu AC.

Immun Inflamm Dis. 2015 Jul 14;3(4):350-9. doi: 10.1002/iid3.73. eCollection 2015 Dec.


Changing patterns of asthma medication use related to US Food and Drug Administration long-acting β2-agonist regulation from 2005-2011.

Butler MG, Zhou EH, Zhang F, Wu YT, Wu AC, Levenson MS, Wu P, Seymour S, Toh S, Iyer A, Iyasu S, Baker MA.

J Allergy Clin Immunol. 2016 Mar;137(3):710-7. doi: 10.1016/j.jaci.2015.09.057. Epub 2015 Dec 22.


Genetic differences between two Leishmania major-like strains revealed by suppression subtractive hybridization.

Wu ÂC, Freitas MA, Silva Sde O, Nogueira PM, Soares RP, Pesquero JB, Gomes MA, Pesquero JL, Melo MN.

Mol Biochem Parasitol. 2015 Sep-Oct;203(1-2):34-8. doi: 10.1016/j.molbiopara.2015.10.005. Epub 2015 Nov 2.


Pharmacogenomic test that predicts response to β2-agonists in adults with asthma is cost effective.

Wu AC, Gay C, Rett MD, Fuhlbrigge AL.

Per Med. 2015 Nov;12(6):574-584. doi: 10.2217/pme.15.23.


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