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Evolutionary history of human colitis-associated colorectal cancer.

Baker AM, Cross W, Curtius K, Al Bakir I, Choi CR, Davis HL, Temko D, Biswas S, Martinez P, Williams MJ, Lindsay JO, Feakins R, Vega R, Hayes SJ, Tomlinson IPM, McDonald SAC, Moorghen M, Silver A, East JE, Wright NA, Wang LM, Rodriguez-Justo M, Jansen M, Hart AL, Leedham SJ, Graham TA.

Gut. 2018 Jul 10. pii: gutjnl-2018-316191. doi: 10.1136/gutjnl-2018-316191. [Epub ahead of print]


Is Barrett's-Associated Esophageal Adenocarcinoma a Clonal Disease?

Wright NA.

Dig Dis Sci. 2018 Aug;63(8):2022-2027. doi: 10.1007/s10620-018-5164-7. Review.


Does human endometrial LGR5 gene expression suggest the existence of another hormonally regulated epithelial stem cell niche?

Tempest N, Baker AM, Wright NA, Hapangama DK.

Hum Reprod. 2018 Jun 1;33(6):1052-1062. doi: 10.1093/humrep/dey083.


Hydroxyurea for lifelong transfusion-dependent β-thalassemia: A meta-analysis.

Algiraigri AH, Wright NAM, Paolucci EO, Kassam A.

Pediatr Hematol Oncol. 2017 Nov;34(8):435-448. doi: 10.1080/08880018.2017.1354948. Epub 2018 Jan 16. Review.


Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.

Baker AM, Huang W, Wang XM, Jansen M, Ma XJ, Kim J, Anderson CM, Wu X, Pan L, Su N, Luo Y, Domingo E, Heide T, Sottoriva A, Lewis A, Beggs AD, Wright NA, Rodriguez-Justo M, Park E, Tomlinson I, Graham TA.

Nat Commun. 2017 Dec 8;8(1):1998. doi: 10.1038/s41467-017-02295-5.


An evolutionary perspective on field cancerization.

Curtius K, Wright NA, Graham TA.

Nat Rev Cancer. 2018 Jan;18(1):19-32. doi: 10.1038/nrc.2017.102. Epub 2017 Dec 8. Review.


Analysis of clonal expansions through the normal and premalignant human breast epithelium reveals the presence of luminal stem cells.

Cereser B, Jansen M, Austin E, Elia G, McFarlane T, van Deurzen CH, Sieuwerts AM, Daidone MG, Tadrous PJ, Wright NA, Jones L, McDonald SA.

J Pathol. 2018 Jan;244(1):61-70. doi: 10.1002/path.4989. Epub 2017 Nov 23.


Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells.

Sundaresan S, Meininger CA, Kang AJ, Photenhauer AL, Hayes MM, Sahoo N, Grembecka J, Cierpicki T, Ding L, Giordano TJ, Else T, Madrigal DJ, Low MJ, Campbell F, Baker AM, Xu H, Wright NA, Merchant JL.

Gastroenterology. 2017 Dec;153(6):1555-1567.e15. doi: 10.1053/j.gastro.2017.08.038. Epub 2017 Aug 30.


Multipotent Basal Stem Cells, Maintained in Localized Proximal Niches, Support Directed Long-Ranging Epithelial Flows in Human Prostates.

Moad M, Hannezo E, Buczacki SJ, Wilson L, El-Sherif A, Sims D, Pickard R, Wright NA, Williamson SC, Turnbull DM, Taylor RW, Greaves L, Robson CN, Simons BD, Heer R.

Cell Rep. 2017 Aug 15;20(7):1609-1622. doi: 10.1016/j.celrep.2017.07.061.


A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance.

Spechler SJ, Merchant JL, Wang TC, Chandrasoma P, Fox JG, Genta RM, Goldenring JR, Hayakawa Y, Kuipers EJ, Lund PK, McKeon F, Mills JC, Odze RD, Peek RM Jr, Pham T, Que J, Rustgi AK, Shaheen NJ, Shivdasani RA, Souza RF, Storz P, Todisco A, Wang DH, Wright NA.

Gastroenterology. 2017 Jul;153(1):e6-e13. doi: 10.1053/j.gastro.2017.05.050. Epub 2017 Jun 3. No abstract available.


Evolution of Premalignant Disease.

Curtius K, Wright NA, Graham TA.

Cold Spring Harb Perspect Med. 2017 Dec 1;7(12). pii: a026542. doi: 10.1101/cshperspect.a026542. Review.


Hydroxyurea for nontransfusion-dependent β-thalassemia: A systematic review and meta-analysis.

Algiraigri AH, Wright NAM, Paolucci EO, Kassam A.

Hematol Oncol Stem Cell Ther. 2017 Sep;10(3):116-125. doi: 10.1016/j.hemonc.2017.02.002. Epub 2017 Apr 6. Review.


Postpartum HLA-Matched Bone Marrow Donation from Mother to Neonate for Reticular Dysgenesis.

Guilcher GM, Wright NA, Truong TH, Daly A, Lewis VA.

J Clin Immunol. 2017 Jan;37(1):29-31. doi: 10.1007/s10875-016-0355-5. Epub 2016 Dec 3. No abstract available.


Segmental stiff skin syndrome (SSS): Two additional cases with a positive response to mycophenolate mofetil and physical therapy.

Kurtzman DJ, Wright NA, Patel M, Vleugels RA.

J Am Acad Dermatol. 2016 Dec;75(6):e237-e239. doi: 10.1016/j.jaad.2016.05.047. No abstract available.


Characteristics and treatment of postirradiation morphea: A retrospective multicenter analysis.

Fruchter R, Kurtzman DJB, Mazori DR, Wright NA, Patel M, Vleugels RA, Femia AN.

J Am Acad Dermatol. 2017 Jan;76(1):19-21. doi: 10.1016/j.jaad.2016.08.059. Epub 2016 Sep 28. No abstract available.


Distal Esophageal Adenocarcinoma and Gastric Adenocarcinoma: Time for a Shared Research Agenda.

Jansen M, Wright NA.

Adv Exp Med Biol. 2016;908:1-8. doi: 10.1007/978-3-319-41388-4_1.


New paradigms in clonal evolution: punctuated equilibrium in cancer.

Cross WCh, Graham TA, Wright NA.

J Pathol. 2016 Oct;240(2):126-36. doi: 10.1002/path.4757. Epub 2016 Aug 24. Review.


Unilateral Gottron Papules in a Patient Following a Stroke: Clinical Insights Into the Disease Mechanisms and Pathophysiology of Cutaneous Dermatomyositis.

Kurtzman DJ, Ho A, Wright NA, Rubenstein MH, Vleugels RA.

JAMA Dermatol. 2016 Sep 1;152(9):1062-3. doi: 10.1001/jamadermatol.2016.1537. No abstract available.


Tofacitinib Citrate for Refractory Cutaneous Dermatomyositis: An Alternative Treatment.

Kurtzman DJ, Wright NA, Lin J, Femia AN, Merola JF, Patel M, Vleugels RA.

JAMA Dermatol. 2016 Aug 1;152(8):944-5. doi: 10.1001/jamadermatol.2016.0866. No abstract available.


Predictable evolution toward flightlessness in volant island birds.

Wright NA, Steadman DW, Witt CC.

Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):4765-70. doi: 10.1073/pnas.1522931113. Epub 2016 Apr 11.


Characteristics and treatment of adult-onset linear morphea: A retrospective cohort study of 61 patients at 3 tertiary care centers.

Mazori DR, Wright NA, Patel M, Liu SW, Ramachandran SM, Franks AG Jr, Vleugels RA, Femia AN.

J Am Acad Dermatol. 2016 Mar;74(3):577-9. doi: 10.1016/j.jaad.2015.09.069. No abstract available.


Novel application of high-dose rate brachytherapy for severe, recalcitrant palmoplantar pustulosis.

Timerman D, Devlin PM, Nambudiri VE, Wright NA, Vleugels RA, Clark RA, Kupper TS, Merola JF, Patel M.

Clin Exp Dermatol. 2016 Jul;41(5):498-501. doi: 10.1111/ced.12803. Epub 2016 Feb 5.


Distribution of the c-MYC gene product in colorectal neoplasia.

Baker AM, Van Noorden S, Rodriguez-Justo M, Cohen P, Wright NA, Lampert IA.

Histopathology. 2016 Aug;69(2):222-9. doi: 10.1111/his.12939. Epub 2016 Mar 17.


Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus.

Lavery DL, Martinez P, Gay LJ, Cereser B, Novelli MR, Rodriguez-Justo M, Meijer SL, Graham TA, McDonald SA, Wright NA, Jansen M.

Gut. 2016 Jun;65(6):907-13. doi: 10.1136/gutjnl-2015-310748. Epub 2015 Dec 23.


Skin Signs of Rheumatoid Arthritis and its Therapy-Induced Cutaneous Side Effects.

Xue Y, Cohen JM, Wright NA, Merola JF.

Am J Clin Dermatol. 2016 Apr;17(2):147-62. doi: 10.1007/s40257-015-0167-z. Review.


Cutaneous dermatomyositis in the era of biologicals.

Wright NA, Vleugels RA, Callen JP.

Semin Immunopathol. 2016 Jan;38(1):113-21. doi: 10.1007/s00281-015-0543-z. Epub 2015 Nov 12. Review.


Epidemiology and Treatment of Eosinophilic Fasciitis: An Analysis of 63 Patients From 3 Tertiary Care Centers.

Wright NA, Mazori DR, Patel M, Merola JF, Femia AN, Vleugels RA.

JAMA Dermatol. 2016 Jan;152(1):97-9. doi: 10.1001/jamadermatol.2015.3648. No abstract available.


Combined Autoimmune Cytopenias Presenting in Childhood.

Al Ghaithi I, Wright NA, Breakey VR, Cox K, Warias A, Wong T, O'Connell C, Price V.

Pediatr Blood Cancer. 2016 Feb;63(2):292-8. doi: 10.1002/pbc.25769. Epub 2015 Sep 23.


Epidemiology of concomitant psoriasis and hidradenitis suppurativa (HS): experience of a tertiary medical center.

Patel M, Cohen JM, Wright NA, Merola JF, Qureshi AA, Vleugels RA.

J Am Acad Dermatol. 2015 Oct;73(4):701-2. doi: 10.1016/j.jaad.2015.06.050. No abstract available.


Optimizing equivalence-based instruction: Effects of training protocols on equivalence class formation.

Fienup DM, Wright NA, Fields L.

J Appl Behav Anal. 2015 Sep;48(3):613-31. doi: 10.1002/jaba.234. Epub 2015 Jul 28.


Response to Comments on "Evidence for mesothermy in dinosaurs".

Grady JM, Enquist BJ, Dettweiler-Robinson E, Wright NA, Smith FA.

Science. 2015 May 29;348(6238):982. doi: 10.1126/science.1260299.


Characterization of LGR5 stem cells in colorectal adenomas and carcinomas.

Baker AM, Graham TA, Elia G, Wright NA, Rodriguez-Justo M.

Sci Rep. 2015 Mar 2;5:8654. doi: 10.1038/srep08654.


Epidermal growth factor attenuates tubular necrosis following mercuric chloride damage by regeneration of indigenous, not bone marrow-derived cells.

Yen TH, Alison MR, Goodlad RA, Otto WR, Jeffery R, Cook HT, Wright NA, Poulsom R.

J Cell Mol Med. 2015 Feb;19(2):463-73. doi: 10.1111/jcmm.12478. Epub 2014 Nov 11.


The Barrett's Gland in Phenotype Space.

McDonald SA, Graham TA, Lavery DL, Wright NA, Jansen M.

Cell Mol Gastroenterol Hepatol. 2014 Nov 12;1(1):41-54. doi: 10.1016/j.jcmgh.2014.10.001. eCollection 2015 Jan. Review.


Barrett oesophagus: lessons on its origins from the lesion itself.

McDonald SA, Lavery D, Wright NA, Jansen M.

Nat Rev Gastroenterol Hepatol. 2015 Jan;12(1):50-60. doi: 10.1038/nrgastro.2014.181. Epub 2014 Nov 4. Review.


Quantification of crypt and stem cell evolution in the normal and neoplastic human colon.

Baker AM, Cereser B, Melton S, Fletcher AG, Rodriguez-Justo M, Tadrous PJ, Humphries A, Elia G, McDonald SA, Wright NA, Simons BD, Jansen M, Graham TA.

Cell Rep. 2014 Aug 21;8(4):940-7. doi: 10.1016/j.celrep.2014.07.019. Epub 2014 Aug 7.


Boveri at 100: cancer evolution, from preneoplasia to malignancy.

Wright NA.

J Pathol. 2014 Oct;234(2):146-51. doi: 10.1002/path.4408.


Dinosaur physiology. Evidence for mesothermy in dinosaurs.

Grady JM, Enquist BJ, Dettweiler-Robinson E, Wright NA, Smith FA.

Science. 2014 Jun 13;344(6189):1268-72. doi: 10.1126/science.1253143. Epub 2014 Jun 12.


Squamous cell carcinoma after radiofrequency ablation for Barrett's dysplasia.

Zeki SS, Haidry R, Justo-Rodriguez M, Lovat LB, Wright NA, McDonald SA.

World J Gastroenterol. 2014 Apr 21;20(15):4453-6. doi: 10.3748/wjg.v20.i15.4453.


The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands.

Lavery DL, Nicholson AM, Poulsom R, Jeffery R, Hussain A, Gay LJ, Jankowski JA, Zeki SS, Barr H, Harrison R, Going J, Kadirkamanathan S, Davis P, Underwood T, Novelli MR, Rodriguez-Justo M, Shepherd N, Jansen M, Wright NA, McDonald SA.

Gut. 2014 Dec;63(12):1854-63. doi: 10.1136/gutjnl-2013-306508. Epub 2014 Feb 18.


Cell migration leads to spatially distinct but clonally related airway cancer precursors.

Pipinikas CP, Kiropoulos TS, Teixeira VH, Brown JM, Varanou A, Falzon M, Capitanio A, Bottoms SE, Carroll B, Navani N, McCaughan F, George JP, Giangreco A, Wright NA, McDonald SA, Graham TA, Janes SM.

Thorax. 2014 Jun;69(6):548-57. doi: 10.1136/thoraxjnl-2013-204198. Epub 2014 Feb 18.


Post-varicella-zoster virus granulomatous dermatitis: a report of 2 cases.

Wright NA, Torres-Cabala CA, Curry JL, Cutlan JE, Hymes SR.

Cutis. 2014 Jan;93(1):50-4. Review.


Metabolic 'engines' of flight drive genome size reduction in birds.

Wright NA, Gregory TR, Witt CC.

Proc Biol Sci. 2014 Jan 29;281(1779):20132780. doi: 10.1098/rspb.2013.2780. Print 2014 Mar 22.


Proteinase activated receptor 1 mediated fibrosis in a mouse model of liver injury: a role for bone marrow derived macrophages.

Kallis YN, Scotton CJ, Mackinnon AC, Goldin RD, Wright NA, Iredale JP, Chambers RC, Forbes SJ.

PLoS One. 2014 Jan 27;9(1):e86241. doi: 10.1371/journal.pone.0086241. eCollection 2014.


Re: Mitochondria and tumor progression in ulcerative colitis.

Jawad N, Graham TA, McDonald SA, Wright NA.

J Natl Cancer Inst. 2014 Feb;106(2):djt436. doi: 10.1093/jnci/djt436. Epub 2014 Jan 8. No abstract available.


Granulomatous lymphocytic interstitial lung disease in infancy.

Adeleye A, Kelly M, Wright NA, Yu W, Anselmo MA.

Can Respir J. 2014 Jan-Feb;21(1):20-2. Epub 2013 Nov 28.


Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors.

Teixeira VH, Nadarajan P, Graham TA, Pipinikas CP, Brown JM, Falzon M, Nye E, Poulsom R, Lawrence D, Wright NA, McDonald S, Giangreco A, Simons BD, Janes SM.

Elife. 2013 Oct 22;2:e00966. doi: 10.7554/eLife.00966.


Clonal selection and persistence in dysplastic Barrett's esophagus and intramucosal cancers after failed radiofrequency ablation.

Zeki SS, Haidry R, Graham TA, Rodriguez-Justo M, Novelli M, Hoare J, Dunn J, Wright NA, Lovat LB, McDonald SA.

Am J Gastroenterol. 2013 Oct;108(10):1584-92. doi: 10.1038/ajg.2013.238. Epub 2013 Aug 13.


Functional role of CD44v-xCT system in the development of spasmolytic polypeptide-expressing metaplasia.

Wada T, Ishimoto T, Seishima R, Tsuchihashi K, Yoshikawa M, Oshima H, Oshima M, Masuko T, Wright NA, Furuhashi S, Hirashima K, Baba H, Kitagawa Y, Saya H, Nagano O.

Cancer Sci. 2013 Oct;104(10):1323-9. doi: 10.1111/cas.12236. Epub 2013 Aug 12.


Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.

Humphries A, Cereser B, Gay LJ, Miller DS, Das B, Gutteridge A, Elia G, Nye E, Jeffery R, Poulsom R, Novelli MR, Rodriguez-Justo M, McDonald SA, Wright NA, Graham TA.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2490-9. doi: 10.1073/pnas.1220353110. Epub 2013 Jun 13.

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