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Items: 1 to 50 of 162


The association of pregnane X receptor activation with outcomes after liver transplantation-A retrospective study.

Amer A, McColl K, Bouayyad S, Kanwar A, Sen G, French JJ, Wilson CH, Manas DM, Wright MC, White SA.

Clin Transplant. 2019 Oct 19:e13734. doi: 10.1111/ctr.13734. [Epub ahead of print]


AAV2-BDNF promotes respiratory axon plasticity and recovery of diaphragm function following spinal cord injury.

Charsar BA, Brinton MA, Locke K, Chen AY, Ghosh B, Urban MW, Komaravolu S, Krishnamurthy K, Smit R, Pasinelli P, Wright MC, Smith GM, Lepore AC.

FASEB J. 2019 Oct 2:fj201901730R. doi: 10.1096/fj.201901730R. [Epub ahead of print]


High-stakes assessment in anesthesia via simulation: Are we there yet?

Wright MC.

Can J Anaesth. 2019 Dec;66(12):1431-1436. doi: 10.1007/s12630-019-01489-3. Epub 2019 Sep 27. No abstract available.


Ionic Liquids: New Emerging Pollutants, Similarities with Perfluorinated Alkyl Substances (PFASs).

Oskarsson A, Wright MC.

Environ Sci Technol. 2019 Sep 17;53(18):10539-10541. doi: 10.1021/acs.est.9b04778. Epub 2019 Aug 23. No abstract available.


Long-Distance Axon Regeneration Promotes Recovery of Diaphragmatic Respiratory Function after Spinal Cord Injury.

Urban MW, Ghosh B, Block CG, Strojny LR, Charsar BA, Goulão M, Komaravolu SS, Smith GM, Wright MC, Li S, Lepore AC.

eNeuro. 2019 Sep 26;6(5). pii: ENEURO.0096-19.2019. doi: 10.1523/ENEURO.0096-19.2019. Print 2019 Sep/Oct.


Critical care information display approaches and design frameworks: A systematic review and meta-analysis.

Wright MC, Borbolla D, Waller RG, Del Fiol G, Reese T, Nesbitt P, Segall N.

J Biomed Inform X. 2019 Sep;3. pii: 100041. doi: 10.1016/j.yjbinx.2019.100041. Epub 2019 Jun 22.


Protein Tyrosine Phosphatase σ Inhibitory Peptide Promotes Recovery of Diaphragm Function and Sprouting of Bulbospinal Respiratory Axons after Cervical Spinal Cord Injury.

Urban MW, Ghosh B, Block CG, Charsar BA, Smith GM, Wright MC, Li S, Lepore AC.

J Neurotrauma. 2019 Sep 18. doi: 10.1089/neu.2019.6586. [Epub ahead of print]


Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes.

Alsaeedi F, Wilson R, Candlish C, Ibrahim I, Leitch AC, Abdelghany TM, Wilson C, Armstrong L, Wright MC.

PLoS One. 2019 Jun 26;14(6):e0218135. doi: 10.1371/journal.pone.0218135. eCollection 2019.


A hydrogel engineered to deliver minocycline locally to the injured cervical spinal cord protects respiratory neural circuitry and preserves diaphragm function.

Ghosh B, Nong J, Wang Z, Urban MW, Heinsinger NM, Trovillion VA, Wright MC, Lepore AC, Zhong Y.

Neurobiol Dis. 2019 Jul;127:591-604. doi: 10.1016/j.nbd.2019.04.014. Epub 2019 Apr 25.


Novel displays of patient information in critical care settings: a systematic review.

Waller RG, Wright MC, Segall N, Nesbitt P, Reese T, Borbolla D, Del Fiol G.

J Am Med Inform Assoc. 2019 May 1;26(5):479-489. doi: 10.1093/jamia/ocy193.


Cost-Efficient and Easy to Perform PCR-Based Assay to Identify Met Exon 14 Skipping in Formalin-Fixed Paraffin-Embedded (FFPE) Non-Small Cell Lung Cancer (NSCLC) Samples.

O'Brien O, Wright MC, O'Brien C, Geoghegan O, Leonard N, Nicholson S, Cuffe S, Fabre A, Jochum W, Joerger M, Gray SG, Finn SP.

Diagnostics (Basel). 2019 Jan 18;9(1). pii: E13. doi: 10.3390/diagnostics9010013.


Astrocyte progenitor transplantation promotes regeneration of bulbospinal respiratory axons, recovery of diaphragm function, and a reduced macrophage response following cervical spinal cord injury.

Goulão M, Ghosh B, Urban MW, Sahu M, Mercogliano C, Charsar BA, Komaravolu S, Block CG, Smith GM, Wright MC, Lepore AC.

Glia. 2019 Mar;67(3):452-466. doi: 10.1002/glia.23555. Epub 2018 Dec 11.


Kappa Opioid Receptor Distribution and Function in Primary Afferents.

Snyder LM, Chiang MC, Loeza-Alcocer E, Omori Y, Hachisuka J, Sheahan TD, Gale JR, Adelman PC, Sypek EI, Fulton SA, Friedman RL, Wright MC, Duque MG, Lee YS, Hu Z, Huang H, Cai X, Meerschaert KA, Nagarajan V, Hirai T, Scherrer G, Kaplan DH, Porreca F, Davis BM, Gold MS, Koerber HR, Ross SE.

Neuron. 2018 Sep 19;99(6):1274-1288.e6. doi: 10.1016/j.neuron.2018.08.044.


Longitudinal Assessment of Critical Thinking Skills Across a Dental Curriculum.

Everett AC, Anderson OS, Wright MC, Fontana M.

J Dent Educ. 2018 Sep;82(9):921-928. doi: 10.21815/JDE.018.088.


The ionic liquid 1-octyl-3-methylimidazolium (M8OI) is an activator of the human estrogen receptor alpha.

Leitch AC, Lakey AF, Hotham WE, Agius L, Kass GEN, Blain PG, Wright MC.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):2167-2172. doi: 10.1016/j.bbrc.2018.08.008. Epub 2018 Aug 4.


Patient information organization in the intensive care setting: expert knowledge elicitation with card sorting methods.

Reese T, Segall N, Nesbitt P, Del Fiol G, Waller R, Macpherson BC, Tonna JE, Wright MC.

J Am Med Inform Assoc. 2018 Aug 1;25(8):1026-1035. doi: 10.1093/jamia/ocy045.


HNF4alpha expression amplifies the glucocorticoid-induced conversion of a human pancreatic cell line to an hepatocyte-like cell.

Fairhall EA, Leitch AC, Lakey AF, Abdelghany TM, Ibrahim I, Tosh D, Kass GEN, Wilson C, Wright MC.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1633-1640. doi: 10.1016/j.bbrc.2018.07.092. Epub 2018 Jul 26.


Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis.

Probert PM, Leitch AC, Dunn MP, Meyer SK, Palmer JM, Abdelghany TM, Lakey AF, Cooke MP, Talbot H, Wills C, McFarlane W, Blake LI, Rosenmai AK, Oskarsson A, Figueiredo R, Wilson C, Kass GE, Jones DE, Blain PG, Wright MC.

J Hepatol. 2018 Nov;69(5):1123-1135. doi: 10.1016/j.jhep.2018.06.027. Epub 2018 Jul 11.


Local BDNF Delivery to the Injured Cervical Spinal Cord using an Engineered Hydrogel Enhances Diaphragmatic Respiratory Function.

Ghosh B, Wang Z, Nong J, Urban MW, Zhang Z, Trovillion VA, Wright MC, Zhong Y, Lepore AC.

J Neurosci. 2018 Jun 27;38(26):5982-5995. doi: 10.1523/JNEUROSCI.3084-17.2018. Epub 2018 Jun 11.


Glucocorticoid-induced pancreatic-hepatic trans-differentiation in a human cell line in vitro.

Fairhall EA, Leitch AC, Lakey AF, Probert PME, Richardson G, De Santis C, Wright MC.

Differentiation. 2018 Jul - Aug;102:10-18. doi: 10.1016/j.diff.2018.05.003. Epub 2018 May 22.


Cell-type specific expression of constitutively-active Rheb promotes regeneration of bulbospinal respiratory axons following cervical SCI.

Urban MW, Ghosh B, Strojny LR, Block CG, Blazejewski SM, Wright MC, Smith GM, Lepore AC.

Exp Neurol. 2018 May;303:108-119. doi: 10.1016/j.expneurol.2018.02.007. Epub 2018 Feb 14.


Notch pathway signaling in the skin antagonizes Merkel cell development.

Logan GJ, Wright MC, Kubicki AC, Maricich SM.

Dev Biol. 2018 Feb 15;434(2):207-214. doi: 10.1016/j.ydbio.2017.12.007. Epub 2017 Dec 11.


Concomitant thyroid disease and primary hyperparathyroidism in patients undergoing parathyroidectomy or thyroidectomy.

Wright MC, Jensen K, Mohamed H, Drake C, Mohsin K, Monlezun D, Alsaleh N, Kandil E.

Gland Surg. 2017 Aug;6(4):368-374. doi: 10.21037/gs.2017.04.01.


B-13 progenitor-derived hepatocytes (B-13/H cells) model lipid dysregulation in response to drugs and chemicals.

Leitch AC, Probert PME, Shayman JA, Meyer SK, Kass GEN, Wright MC.

Toxicology. 2017 Jul 1;386:120-132. doi: 10.1016/j.tox.2017.05.014. Epub 2017 May 26.


Auditory inspired machine learning techniques can improve speech intelligibility and quality for hearing-impaired listeners.

Monaghan JJ, Goehring T, Yang X, Bolner F, Wang S, Wright MC, Bleeck S.

J Acoust Soc Am. 2017 Mar;141(3):1985. doi: 10.1121/1.4977197.


Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse.

Meyer SK, Probert PME, Lakey AF, Axon AR, Leitch AC, Williams FM, Jowsey PA, Blain PG, Kass GEN, Wright MC.

Toxicol Lett. 2017 May 5;273:55-68. doi: 10.1016/j.toxlet.2017.03.024. Epub 2017 Mar 27.


Effects of image-based and text-based active learning exercises on student examination performance in a musculoskeletal anatomy course.

Gross MM, Wright MC, Anderson OS.

Anat Sci Educ. 2017 Sep;10(5):444-455. doi: 10.1002/ase.1684. Epub 2017 Feb 7.


Oral administration of amphotericin B nanoparticles: antifungal activity, bioavailability and toxicity in rats.

Radwan MA, AlQuadeib BT, Šiller L, Wright MC, Horrocks B.

Drug Deliv. 2017 Nov;24(1):40-50. doi: 10.1080/10717544.2016.1228715.


Environmental Xenoestrogens Super-Activate a Variant Murine ER Beta in Cholangiocytes.

Meyer SK, Probert PM, Lakey AK, Leitch AC, Blake LI, Jowsey PA, Cooke MP, Blain PG, Wright MC.

Toxicol Sci. 2017 Mar 1;156(1):54-71. doi: 10.1093/toxsci/kfw234.


Merkel cells are long-lived cells whose production is stimulated by skin injury.

Wright MC, Logan GJ, Bolock AM, Kubicki AC, Hemphill JA, Sanders TA, Maricich SM.

Dev Biol. 2017 Feb 1;422(1):4-13. doi: 10.1016/j.ydbio.2016.12.020. Epub 2016 Dec 18.


How Do Simulated Error Experiences Impact Attitudes Related to Error Prevention?

Breitkreuz KR, Dougal RL, Wright MC.

Simul Healthc. 2016 Oct;11(5):323-333.


Toward Designing Information Display to Support Critical Care. A Qualitative Contextual Evaluation and Visioning Effort.

Wright MC, Dunbar S, Macpherson BC, Moretti EW, Del Fiol G, Bolte J, Taekman JM, Segall N.

Appl Clin Inform. 2016 Oct 5;7(4):912-929.


Operating Room-to-ICU Patient Handovers: A Multidisciplinary Human-Centered Design Approach.

Segall N, Bonifacio AS, Barbeito A, Schroeder RA, Perfect SR, Wright MC, Emery JD, Atkins BZ, Taekman JM, Mark JB.

Jt Comm J Qual Patient Saf. 2016 Sep;42(9):400-14.


Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes.

Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM.

J Neurosci. 2016 Apr 13;36(15):4362-76. doi: 10.1523/JNEUROSCI.3781-15.2016.


A new fluorescence-based optical imaging method to non-invasively monitor hepatic myofibroblasts in vivo.

Luli S, Di Paolo D, Perri P, Brignole C, Hill SJ, Brown H, Leslie J, Marshall HL, Wright MC, Mann DA, Ponzoni M, Oakley F.

J Hepatol. 2016 Jul;65(1):75-83. doi: 10.1016/j.jhep.2016.03.021. Epub 2016 Apr 9.


Spaced learning using emails to integrate psychiatry into general medical curriculum: Keep psychiatry in mind.

Blazek MC, Dantz B, Wright MC, Fiedorowicz JG.

Med Teach. 2016 Oct;38(10):1049-1055. Epub 2016 Mar 30.


Pancreatic B-13 Cell Trans-Differentiation to Hepatocytes Is Dependent on Epigenetic-Regulated Changes in Gene Expression.

Fairhall EA, Charles MA, Probert PM, Wallace K, Gibb J, Ravindan C, Soloman M, Wright MC.

PLoS One. 2016 Mar 8;11(3):e0150959. doi: 10.1371/journal.pone.0150959. eCollection 2016.


Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1'-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism.

Probert PM, Palmer JM, Alhusainy W, Amer AO, Rietjens IM, White SA, Jones DE, Wright MC.

Toxicol Lett. 2016 Jan 22;243:98-110. doi: 10.1016/j.toxlet.2015.12.010. Epub 2015 Dec 29.


Pancreatic progenitor-derived hepatocytes are viable and functional in a 3D high density bioreactor culture system.

Richter M, Fairhall EA, Hoffmann SA, Tröbs S, Knöspel F, Probert PME, Oakley F, Stroux A, Wright MC, Zeilinger K.

Toxicol Res (Camb). 2015 Nov 18;5(1):278-290. doi: 10.1039/c5tx00187k. eCollection 2016 Jan 1.


Association Between Dental Student-Developed Exam Questions and Learning at Higher Cognitive Levels.

Gonzalez-Cabezas C, Anderson OS, Wright MC, Fontana M.

J Dent Educ. 2015 Nov;79(11):1295-304.


Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation.

Amer AO, Probert PM, Dunn M, Knight M, Vallance AE, Flecknell PA, Oakley F, Cameron I, White SA, Blain PG, Wright MC.

PLoS One. 2015 Aug 24;10(8):e0136173. doi: 10.1371/journal.pone.0136173. eCollection 2015.


Hepatic stellate cells regulate liver immunity to visceral leishmaniasis through P110δ-dependent induction and expansion of regulatory T cells in mice.

Khadem F, Gao X, Mou Z, Jia P, Movassagh H, Onyilagha C, Gounni AS, Wright MC, Uzonna JE.

Hepatology. 2016 Feb;63(2):620-32. doi: 10.1002/hep.28130. Epub 2015 Oct 10.


Human iPS cell-derived astrocyte transplants preserve respiratory function after spinal cord injury.

Li K, Javed E, Scura D, Hala TJ, Seetharam S, Falnikar A, Richard JP, Chorath A, Maragakis NJ, Wright MC, Lepore AC.

Exp Neurol. 2015 Sep;271:479-92. doi: 10.1016/j.expneurol.2015.07.020. Epub 2015 Jul 26.


Ectopic Atoh1 expression drives Merkel cell production in embryonic, postnatal and adult mouse epidermis.

Ostrowski SM, Wright MC, Bolock AM, Geng X, Maricich SM.

Development. 2015 Jul 15;142(14):2533-44. doi: 10.1242/dev.123141. Epub 2015 Jul 2.


Stealth Amphotericin B nanoparticles for oral drug delivery: In vitro optimization.

Al-Quadeib BT, Radwan MA, Siller L, Horrocks B, Wright MC.

Saudi Pharm J. 2015 Jul;23(3):290-302. doi: 10.1016/j.jsps.2014.11.004. Epub 2014 Nov 20.


Functional and morphological assessment of diaphragm innervation by phrenic motor neurons.

Martin M, Li K, Wright MC, Lepore AC.

J Vis Exp. 2015 May 25;(99):e52605. doi: 10.3791/52605.


GLT1 overexpression in SOD1(G93A) mouse cervical spinal cord does not preserve diaphragm function or extend disease.

Li K, Hala TJ, Seetharam S, Poulsen DJ, Wright MC, Lepore AC.

Neurobiol Dis. 2015 Jun;78:12-23. doi: 10.1016/j.nbd.2015.03.010. Epub 2015 Mar 25.


Patient load effects on response time to critical arrhythmias in cardiac telemetry: a randomized trial.

Segall N, Hobbs G, Granger CB, Anderson AE, Bonifacio AS, Taekman JM, Wright MC.

Crit Care Med. 2015 May;43(5):1036-42. doi: 10.1097/CCM.0000000000000923.


Unipotent, Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice.

Wright MC, Reed-Geaghan EG, Bolock AM, Fujiyama T, Hoshino M, Maricich SM.

J Cell Biol. 2015 Feb 2;208(3):367-79. doi: 10.1083/jcb.201407101. Epub 2015 Jan 26.


Developing Adnectins that target SRC co-activator binding to PXR: a structural approach toward understanding promiscuity of PXR.

Khan JA, Camac DM, Low S, Tebben AJ, Wensel DL, Wright MC, Su J, Jenny V, Gupta RD, Ruzanov M, Russo KA, Bell A, An Y, Bryson JW, Gao M, Gambhire P, Baldwin ET, Gardner D, Cavallaro CL, Duncia JV, Hynes J Jr.

J Mol Biol. 2015 Feb 27;427(4):924-942. doi: 10.1016/j.jmb.2014.12.022. Epub 2015 Jan 8.


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