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Items: 48

1.

Dual PPARα/γ agonist aleglitazar confers stroke protection in a model of mild focal brain ischemia in mice.

Boujon V, Uhlemann R, Wegner S, Wright MB, Laufs U, Endres M, Kronenberg G, Gertz K.

J Mol Med (Berl). 2019 Aug;97(8):1127-1138. doi: 10.1007/s00109-019-01801-0. Epub 2019 May 30.

2.

Insulin Receptor and Glucose Transporters in the Mammalian Cochlea.

Huerzeler N, Petkovic V, Sekulic-Jablanovic M, Kucharava K, Wright MB, Bodmer D.

Audiol Neurootol. 2019;24(2):65-76. doi: 10.1159/000499561. Epub 2019 May 22.

PMID:
31117067
3.

Pioglitazone Represents an Effective Therapeutic Target in Preventing Oxidative/Inflammatory Cochlear Damage Induced by Noise Exposure.

Paciello F, Fetoni AR, Rolesi R, Wright MB, Grassi C, Troiani D, Paludetti G.

Front Pharmacol. 2018 Oct 8;9:1103. doi: 10.3389/fphar.2018.01103. eCollection 2018.

4.

Effects of peroxisome proliferator activated receptors (PPAR)-γ and -α agonists on cochlear protection from oxidative stress.

Sekulic-Jablanovic M, Petkovic V, Wright MB, Kucharava K, Huerzeler N, Levano S, Brand Y, Leitmeyer K, Glutz A, Bausch A, Bodmer D.

PLoS One. 2017 Nov 28;12(11):e0188596. doi: 10.1371/journal.pone.0188596. eCollection 2017.

5.

Urine Drug Testing in a Family Medicine Residency Practice.

Woodall HE, Young N, Davis A, Wright MB.

J Addict Med. 2017 May/Jun;11(3):242-243. doi: 10.1097/ADM.0000000000000284. No abstract available.

PMID:
28557961
6.

Teaching Chronic Pain in Family Medicine.

Davis A, Wright MB, Norris L, Woodall H, Young N, Family Medicine Residency Program AH.

Fam Med. 2016 Nov;48(10):825. No abstract available.

7.

Pasireotide prevents nuclear factor of activated T cells nuclear translocation and acts as a protective agent in aminoglycoside-induced auditory hair cell loss.

Bodmer D, Perkovic A, Sekulic-Jablanovic M, Wright MB, Petkovic V.

J Neurochem. 2016 Dec;139(6):1113-1123. doi: 10.1111/jnc.13880. Epub 2016 Nov 29.

8.

Aldosterone Antagonists or Renin-Guided Therapy for Treatment-Resistant Hypertension: A Comparative Effectiveness Pilot Study in Primary Care.

Egan BM, Laken MA, Sutherland SE, Qanungo S, Fleming DO, Cook AG, Hester WH, Jones KW, Jebaily GC, Valainis GT, Way CF, Wright MB, Davis RA.

Am J Hypertens. 2016 Aug;29(8):976-83. doi: 10.1093/ajh/hpw016. Epub 2016 Apr 13.

9.

Effects of pioglitazone and fenofibrate co-administration on bone biomechanics and histomorphometry in ovariectomized rats.

Smith SY, Samadfam R, Chouinard L, Awori M, Bénardeau A, Bauss F, Guldberg RE, Sebokova E, Wright MB.

J Bone Miner Metab. 2015 Nov;33(6):625-41. doi: 10.1007/s00774-014-0632-4. Epub 2014 Dec 23.

PMID:
25534548
10.

Minireview: Challenges and opportunities in development of PPAR agonists.

Wright MB, Bortolini M, Tadayyon M, Bopst M.

Mol Endocrinol. 2014 Nov;28(11):1756-68. doi: 10.1210/me.2013-1427. Epub 2014 Aug 22. Review.

11.

The dual PPARα/γ agonist aleglitazar increases the number and function of endothelial progenitor cells: implications for vascular function and atherogenesis.

Werner CM, Schirmer SH, Gensch C, Pavlickova V, Pöss J, Wright MB, Böhm M, Laufs U.

Br J Pharmacol. 2014 May;171(10):2685-703. doi: 10.1111/bph.12608.

12.

6-Alkoxy-5-aryl-3-pyridinecarboxamides, a new series of bioavailable cannabinoid receptor type 1 (CB1) antagonists including peripherally selective compounds.

Röver S, Andjelkovic M, Bénardeau A, Chaput E, Guba W, Hebeisen P, Mohr S, Nettekoven M, Obst U, Richter WF, Ullmer C, Waldmeier P, Wright MB.

J Med Chem. 2013 Dec 27;56(24):9874-96. doi: 10.1021/jm4010708. Epub 2013 Nov 20.

PMID:
24175572
13.

Examining the safety of PPAR agonists - current trends and future prospects.

Bortolini M, Wright MB, Bopst M, Balas B.

Expert Opin Drug Saf. 2013 Jan;12(1):65-79. doi: 10.1517/14740338.2013.741585. Epub 2012 Nov 8. Review.

PMID:
23134541
14.

Effects of the dual PPAR-α/γ agonist aleglitazar on glycaemic control and organ protection in the Zucker diabetic fatty rat.

Bénardeau A, Verry P, Atzpodien EA, Funk JM, Meyer M, Mizrahi J, Winter M, Wright MB, Uhles S, Sebokova E.

Diabetes Obes Metab. 2013 Feb;15(2):164-74. doi: 10.1111/dom.12006. Epub 2012 Oct 3.

PMID:
22958363
15.

Comparative transcriptional network modeling of three PPAR-α/γ co-agonists reveals distinct metabolic gene signatures in primary human hepatocytes.

Deehan R, Maerz-Weiss P, Catlett NL, Steiner G, Wong B, Wright MB, Blander G, Elliston KO, Ladd W, Bobadilla M, Mizrahi J, Haefliger C, Edgar A.

PLoS One. 2012;7(4):e35012. doi: 10.1371/journal.pone.0035012. Epub 2012 Apr 13.

16.

Comparative molecular profiling of the PPARα/γ activator aleglitazar: PPAR selectivity, activity and interaction with cofactors.

Dietz M, Mohr P, Kuhn B, Maerki HP, Hartman P, Ruf A, Benz J, Grether U, Wright MB.

ChemMedChem. 2012 Jun;7(6):1101-11. doi: 10.1002/cmdc.201100598. Epub 2012 Apr 4.

17.

The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor γ through spatial relocalization at helix 7 of its ligand-binding domain.

Burgermeister E, Friedrich T, Hitkova I, Regel I, Einwächter H, Zimmermann W, Röcken C, Perren A, Wright MB, Schmid RM, Seger R, Ebert MP.

Mol Cell Biol. 2011 Aug;31(16):3497-510. doi: 10.1128/MCB.01421-10. Epub 2011 Jun 20.

18.

Farnesoid X receptor protects human and murine gastric epithelial cells against inflammation-induced damage.

Lian F, Xing X, Yuan G, Schäfer C, Rauser S, Walch A, Röcken C, Ebeling M, Wright MB, Schmid RM, Ebert MP, Burgermeister E.

Biochem J. 2011 Sep 1;438(2):315-23. doi: 10.1042/BJ20102096.

PMID:
21619550
19.

New Insights on the mechanism of PPAR-targeted drugs.

Grether U, Klaus W, Kuhn B, Maerki HP, Mohr P, Wright MB.

ChemMedChem. 2010 Dec 3;5(12):1973-6. doi: 10.1002/cmdc.201000446. No abstract available.

PMID:
21069658
20.

Recent progress in liver X receptor-selective modulators.

Ratni H, Wright MB.

Curr Opin Drug Discov Devel. 2010 Jul;13(4):403-13. Review.

PMID:
20597026
21.

Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1.

Goodnow RA Jr, Hicks A, Sidduri A, Kowalczyk A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Tilley J, Cohen N, Choudhry S, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Tare NS, Oh H, Lamb M, Kurylko G, Hamid R, Wright MB, Pamidimukkala A, Egan T, Gubler U, Hoffman AF, Wei X, Li YL, O'Neil J, Marcano R, Pozzani K, Molinaro T, Santiago J, Singer L, Hargaden M, Moore D, Catala AR, Chao LC, Hermann G, Venkat R, Mancebo H, Renzetti LM.

J Med Chem. 2010 May 13;53(9):3502-16. doi: 10.1021/jm1001919.

PMID:
20380377
22.

Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates.

Hicks A, Goodnow R Jr, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Lora JM, Satjawatcharaphong J, Brovarney M, Dabbagh K, Tare NS, Oh H, Lamb M, Sidduri A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Kowalczyk A, Kurylko G, Hamid R, Wright MB, Pamidimukkala A, Egan T, Gubler U, Hoffman AF, Wei X, Li YL, O'Neil J, Marcano R, Pozzani K, Molinaro T, Santiago J, Singer L, Hargaden M, Moore D, Catala AR, Chao LC, Benson J, March T, Venkat R, Mancebo H, Renzetti LM.

Prostaglandins Other Lipid Mediat. 2010 Jun;92(1-4):33-43. doi: 10.1016/j.prostaglandins.2010.02.003. Epub 2010 Mar 7.

PMID:
20214997
23.

MARCO, a macrophage scavenger receptor highly expressed in rodents, mediates dalcetrapib-induced uptake of lipids by rat and mouse macrophages.

Perez A, Wright MB, Maugeais C, Braendli-Baiocco A, Okamoto H, Takahashi A, Singer T, Mueller L, Niesor EJ.

Toxicol In Vitro. 2010 Apr;24(3):745-50. doi: 10.1016/j.tiv.2010.01.002. Epub 2010 Jan 13.

PMID:
20074633
24.

Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver hypertrophy.

Xing X, Burgermeister E, Geisler F, Einwächter H, Fan L, Hiber M, Rauser S, Walch A, Röcken C, Ebeling M, Wright MB, Schmid RM, Ebert MP.

Hepatology. 2009 Mar;49(3):979-88. doi: 10.1002/hep.22712.

PMID:
19072826
25.

Prevalence of prehypertension and its relationship to risk factors for cardiovascular disease in Jamaica: analysis from a cross-sectional survey.

Ferguson TS, Younger NO, Tulloch-Reid MK, Wright MB, Ward EM, Ashley DE, Wilks RJ.

BMC Cardiovasc Disord. 2008 Aug 28;8:20. doi: 10.1186/1471-2261-8-20.

26.

Synthesis and evaluation of anilinohexafluoroisopropanols as activators/modulators of LXRalpha and beta.

Panday N, Benz J, Blum-Kaelin D, Bourgeaux V, Dehmlow H, Hartman P, Kuhn B, Ratni H, Warot X, Wright MB.

Bioorg Med Chem Lett. 2006 Oct 1;16(19):5231-7. Epub 2006 Jul 31.

PMID:
16876993
27.

Induction of cytochrome P450 3A4 and P-glycoprotein by the isoxazolyl-penicillin antibiotic flucloxacillin.

Huwyler J, Wright MB, Gutmann H, Drewe J.

Curr Drug Metab. 2006 Feb;7(2):119-26.

PMID:
16472102
28.

A novel principle for partial agonism of liver X receptor ligands. Competitive recruitment of activators and repressors.

Albers M, Blume B, Schlueter T, Wright MB, Kober I, Kremoser C, Deuschle U, Koegl M.

J Biol Chem. 2006 Feb 24;281(8):4920-30. Epub 2005 Dec 13.

29.

Born into a diaper.

Burgess AW, Wright MB.

Am J Nurs. 2004 Apr;104(4):66-9. No abstract available.

PMID:
15171117
30.

A receptor-like inositol lipid phosphatase is required for the maturation of developing cochlear hair bundles.

Goodyear RJ, Legan PK, Wright MB, Marcotti W, Oganesian A, Coats SA, Booth CJ, Kros CJ, Seifert RA, Bowen-Pope DF, Richardson GP.

J Neurosci. 2003 Oct 8;23(27):9208-19.

31.

PTPRQ is a novel phosphatidylinositol phosphatase that can be expressed as a cytoplasmic protein or as a subcellularly localized receptor-like protein.

Seifert RA, Coats SA, Oganesian A, Wright MB, Dishmon M, Booth CJ, Johnson RJ, Alpers CE, Bowen-Pope DF.

Exp Cell Res. 2003 Jul 15;287(2):374-86.

PMID:
12837292
32.

Preservation of gene expression ratios among multiple complex cDNAs after PCR amplification: application to differential gene expression studies.

Ji W, Cai L, Wright MB, Walker G, Salgam P, Vater A, Lindpaintner K.

J Struct Funct Genomics. 2000;1(1):1-7.

PMID:
12836675
33.

Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation.

Oganesian A, Poot M, Daum G, Coats SA, Wright MB, Seifert RA, Bowen-Pope DF.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7563-8. Epub 2003 Jun 11.

34.

Efficacy of SSH PCR in isolating differentially expressed genes.

Ji W, Wright MB, Cai L, Flament A, Lindpaintner K.

BMC Genomics. 2002 May 20;3:12. Epub 2002 May 20.

35.

Efficacy of intraarticular hyaluronic acid injections in knee osteoarthritis.

Evanich JD, Evanich CJ, Wright MB, Rydlewicz JA.

Clin Orthop Relat Res. 2001 Sep;(390):173-81.

PMID:
11550864
36.

Different binding modes of amphibian and human corticotropin-releasing factor type 1 and type 2 receptors: evidence for evolutionary differences.

Dautzenberg FM, Py-Lang G, Higelin J, Fischer C, Wright MB, Huber G.

J Pharmacol Exp Ther. 2001 Jan;296(1):113-20.

PMID:
11123370
37.

Cloning, expression and functional characterization of rat napsin.

Schauer-Vukasinovic V, Wright MB, Breu V, Giller T.

Biochim Biophys Acta. 2000 Jun 21;1492(1):207-10.

PMID:
10858550
38.

Protein-tyrosine phosphatases in the vessel wall: differential expression after acute arterial injury.

Wright MB, Seifert RA, Bowen-Pope DF.

Arterioscler Thromb Vasc Biol. 2000 May;20(5):1189-98.

PMID:
10807732
40.

Potassium transport by amino acid permeases in Saccharomyces cerevisiae.

Wright MB, Ramos J, Gomez MJ, Moulder K, Scherrer M, Munson G, Gaber RF.

J Biol Chem. 1997 May 23;272(21):13647-52.

42.

Genetic and molecular analysis of DNA43 and DNA52: two new cell-cycle genes in Saccharomyces cerevisiae.

Solomon NA, Wright MB, Chang S, Buckley AM, Dumas LB, Gaber RF.

Yeast. 1992 Apr;8(4):273-89.

PMID:
1514326
43.

Cervical spine injuries in blunt trauma patients requiring emergent endotracheal intubation.

Wright SW, Robinson GG 2nd, Wright MB.

Am J Emerg Med. 1992 Mar;10(2):104-9.

PMID:
1586400
44.

Ineffectiveness of oral labetalol for hypertensive urgency.

Wright SW, Hedges JR, Wright MB, Chudnofsky CR, MacCarthy EP.

Am J Emerg Med. 1990 Sep;8(5):472-3. No abstract available.

PMID:
2206154
45.

Midazolam use in the emergency department.

Wright SW, Chudnofsky CR, Dronen SC, Wright MB, Borron SW.

Am J Emerg Med. 1990 Mar;8(2):97-100.

PMID:
2302291
46.

The safety of fentanyl use in the emergency department.

Chudnofsky CR, Wright SW, Dronen SC, Borron SW, Wright MB.

Ann Emerg Med. 1989 Jun;18(6):635-9.

PMID:
2729688
47.

TREATMENT OF PSYCHOLOGICAL CASUALTIES DURING WAR.

Wright MB.

Br Med J. 1939 Sep 16;2(4106):615-7. No abstract available.

48.

PSYCHOLOGICAL EMERGENCIES IN WAR TIME.

Wright MB.

Br Med J. 1939 Sep 9;2(4105):576-8. No abstract available.

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