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Items: 29


Flavanone-3-Hydroxylase Plays an Important Role in the Biosynthesis of Spruce Phenolic Defenses Against Bark Beetles and Their Fungal Associates.

Hammerbacher A, Kandasamy D, Ullah C, Schmidt A, Wright LP, Gershenzon J.

Front Plant Sci. 2019 Feb 25;10:208. doi: 10.3389/fpls.2019.00208. eCollection 2019.


The plastidial metabolite 2-C-methyl-D-erythritol-2,4-cyclodiphosphate modulates defence responses against aphids.

Onkokesung N, Reichelt M, Wright LP, Phillips MA, Gershenzon J, Dicke M.

Plant Cell Environ. 2019 Jul;42(7):2309-2323. doi: 10.1111/pce.13538. Epub 2019 Mar 8.


Rust Infection of Black Poplar Trees Reduces Photosynthesis but Does Not Affect Isoprene Biosynthesis or Emission.

Eberl F, Perreca E, Vogel H, Wright LP, Hammerbacher A, Veit D, Gershenzon J, Unsicker SB.

Front Plant Sci. 2018 Nov 27;9:1733. doi: 10.3389/fpls.2018.01733. eCollection 2018.


Beneficial Root Endophytic Fungi Increase Growth and Quality Parameters of Sweet Basil in Heavy Metal Contaminated Soil.

Sabra M, Aboulnasr A, Franken P, Perreca E, Wright LP, Camehl I.

Front Plant Sci. 2018 Nov 27;9:1726. doi: 10.3389/fpls.2018.01726. eCollection 2018.


Gallocatechin biosynthesis via a flavonoid 3',5'-hydroxylase is a defense response in Norway spruce against infection by the bark beetle-associated sap-staining fungus Endoconidiophora polonica.

Hammerbacher A, Raguschke B, Wright LP, Gershenzon J.

Phytochemistry. 2018 Apr;148:78-86. doi: 10.1016/j.phytochem.2018.01.017. Epub 2018 Feb 6.


The Estimated Six-Year Mercury Dry Deposition Across North America.

Zhang L, Wu Z, Cheng I, Wright LP, Olson ML, Gay DA, Risch MR, Brooks S, Castro MS, Conley GD, Edgerton ES, Holsen TM, Luke W, Tordon R, Weiss-Penzias P.

Environ Sci Technol. 2016 Dec 6;50(23):12864-12873. Epub 2016 Nov 22.


Quantifying the Metabolites of the Methylerythritol 4-Phosphate (MEP) Pathway in Plants and Bacteria by Liquid Chromatography-Triple Quadrupole Mass Spectrometry.

González-Cabanelas D, Hammerbacher A, Raguschke B, Gershenzon J, Wright LP.

Methods Enzymol. 2016;576:225-49. doi: 10.1016/bs.mie.2016.02.025. Epub 2016 Mar 24.


The Bark-Beetle-Associated Fungus, Endoconidiophora polonica, Utilizes the Phenolic Defense Compounds of Its Host as a Carbon Source.

Wadke N, Kandasamy D, Vogel H, Lah L, Wingfield BD, Paetz C, Wright LP, Gershenzon J, Hammerbacher A.

Plant Physiol. 2016 Jun;171(2):914-31. doi: 10.1104/pp.15.01916. Epub 2016 Apr 22.


Specific Hsp100 Chaperones Determine the Fate of the First Enzyme of the Plastidial Isoprenoid Pathway for Either Refolding or Degradation by the Stromal Clp Protease in Arabidopsis.

Pulido P, Llamas E, Llorente B, Ventura S, Wright LP, Rodríguez-Concepción M.

PLoS Genet. 2016 Jan 27;12(1):e1005824. doi: 10.1371/journal.pgen.1005824. eCollection 2016 Jan.


The diversion of 2-C-methyl-D-erythritol-2,4-cyclodiphosphate from the 2-C-methyl-D-erythritol 4-phosphate pathway to hemiterpene glycosides mediates stress responses in Arabidopsis thaliana.

González-Cabanelas D, Wright LP, Paetz C, Onkokesung N, Gershenzon J, Rodríguez-Concepción M, Phillips MA.

Plant J. 2015 Apr;82(1):122-37. doi: 10.1111/tpj.12798.


Jasmonic acid and its precursor 12-oxophytodienoic acid control different aspects of constitutive and induced herbivore defenses in tomato.

Bosch M, Wright LP, Gershenzon J, Wasternack C, Hause B, Schaller A, Stintzi A.

Plant Physiol. 2014 Sep;166(1):396-410. doi: 10.1104/pp.114.237388. Epub 2014 Jul 29.


The 2-C-methylerythritol 4-phosphate pathway in melon is regulated by specialized isoforms for the first and last steps.

Saladié M, Wright LP, Garcia-Mas J, Rodriguez-Concepcion M, Phillips MA.

J Exp Bot. 2014 Sep;65(17):5077-92. doi: 10.1093/jxb/eru275. Epub 2014 Jul 10.


Deoxyxylulose 5-Phosphate Synthase Controls Flux through the Methylerythritol 4-Phosphate Pathway in Arabidopsis.

Wright LP, Rohwer JM, Ghirardo A, Hammerbacher A, Ortiz-Alcaide M, Raguschke B, Schnitzler JP, Gershenzon J, Phillips MA.

Plant Physiol. 2014 Aug;165(4):1488-1504. Epub 2014 Jul 1.


Measuring the activity of 1-deoxy-D-xylulose 5-phosphate synthase, the first enzyme in the MEP pathway, in plant extracts.

Wright LP, Phillips MA.

Methods Mol Biol. 2014;1153:9-20. doi: 10.1007/978-1-4939-0606-2_2.


Metabolic flux analysis of plastidic isoprenoid biosynthesis in poplar leaves emitting and nonemitting isoprene.

Ghirardo A, Wright LP, Bi Z, Rosenkranz M, Pulido P, Rodríguez-Concepción M, Niinemets Ü, Brüggemann N, Gershenzon J, Schnitzler JP.

Plant Physiol. 2014 May;165(1):37-51. doi: 10.1104/pp.114.236018. Epub 2014 Mar 3.


Flavan-3-ols in Norway spruce: biosynthesis, accumulation, and function in response to attack by the bark beetle-associated fungus Ceratocystis polonica.

Hammerbacher A, Paetz C, Wright LP, Fischer TC, Bohlmann J, Davis AJ, Fenning TM, Gershenzon J, Schmidt A.

Plant Physiol. 2014 Apr;164(4):2107-22. doi: 10.1104/pp.113.232389. Epub 2014 Feb 18.


Arabidopsis J-protein J20 delivers the first enzyme of the plastidial isoprenoid pathway to protein quality control.

Pulido P, Toledo-Ortiz G, Phillips MA, Wright LP, Rodríguez-Concepción M.

Plant Cell. 2013 Oct;25(10):4183-94. doi: 10.1105/tpc.113.113001. Epub 2013 Oct 8.


A common fungal associate of the spruce bark beetle metabolizes the stilbene defenses of Norway spruce.

Hammerbacher A, Schmidt A, Wadke N, Wright LP, Schneider B, Bohlmann J, Brand WA, Fenning TM, Gershenzon J, Paetz C.

Plant Physiol. 2013 Jul;162(3):1324-36. doi: 10.1104/pp.113.218610. Epub 2013 Jun 1.


A Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignancies.

Fracasso PM, Williams KJ, Chen RC, Picus J, Ma CX, Ellis MJ, Tan BR, Pluard TJ, Adkins DR, Naughton MJ, Rader JS, Arquette MA, Fleshman JW, Creekmore AN, Goodner SA, Wright LP, Guo Z, Ryan CE, Tao Y, Soares EM, Cai SR, Lin L, Dancey J, Rudek MA, McLeod HL, Piwnica-Worms H.

Cancer Chemother Pharmacol. 2011 Jun;67(6):1225-37. doi: 10.1007/s00280-010-1410-1. Epub 2010 Aug 8.


Pleiotropic regulatory locus 1 (PRL1) integrates the regulation of sugar responses with isoprenoid metabolism in Arabidopsis.

Flores-Pérez U, Pérez-Gil J, Closa M, Wright LP, Botella-Pavía P, Phillips MA, Ferrer A, Gershenzon J, Rodríguez-Concepción M.

Mol Plant. 2010 Jan;3(1):101-12. doi: 10.1093/mp/ssp100. Epub 2009 Dec 14.


Topology of mammalian isoprenylcysteine carboxyl methyltransferase determined in live cells with a fluorescent probe.

Wright LP, Court H, Mor A, Ahearn IM, Casey PJ, Philips MR.

Mol Cell Biol. 2009 Apr;29(7):1826-33. doi: 10.1128/MCB.01719-08. Epub 2009 Jan 21.


A phase 1 escalating single-dose and weekly fixed-dose study of cetuximab: pharmacokinetic and pharmacodynamic rationale for dosing.

Fracasso PM, Burris H 3rd, Arquette MA, Govindan R, Gao F, Wright LP, Goodner SA, Greco FA, Jones SF, Willcut N, Chodkiewicz C, Pathak A, Springett GM, Simon GR, Sullivan DM, Marcelpoil R, Mayfield SD, Mauro D, Garrett CR.

Clin Cancer Res. 2007 Feb 1;13(3):986-93.


Thematic review series: lipid posttranslational modifications. CAAX modification and membrane targeting of Ras.

Wright LP, Philips MR.

J Lipid Res. 2006 May;47(5):883-91. Epub 2006 Mar 16. Review.


Phase I study of pegylated liposomal doxorubicin and the multidrug-resistance modulator, valspodar.

Fracasso PM, Blum KA, Ma MK, Tan BR, Wright LP, Goodner SA, Fears CL, Hou W, Arquette MA, Picus J, Denes A, Mortimer JE, Ratner L, Ivy SP, McLeod HL.

Br J Cancer. 2005 Jul 11;93(1):46-53.


Phase I study of docetaxel in combination with the P-glycoprotein inhibitor, zosuquidar, in resistant malignancies.

Fracasso PM, Goldstein LJ, de Alwis DP, Rader JS, Arquette MA, Goodner SA, Wright LP, Fears CL, Gazak RJ, Andre VA, Burgess MF, Slapak CA, Schellens JH.

Clin Cancer Res. 2004 Nov 1;10(21):7220-8.


Phase I and pharmacodynamic study of Triapine, a novel ribonucleotide reductase inhibitor, in patients with advanced leukemia.

Giles FJ, Fracasso PM, Kantarjian HM, Cortes JE, Brown RA, Verstovsek S, Alvarado Y, Thomas DA, Faderl S, Garcia-Manero G, Wright LP, Samson T, Cahill A, Lambert P, Plunkett W, Sznol M, DiPersio JF, Gandhi V.

Leuk Res. 2003 Dec;27(12):1077-83.


Analysis of black tea theaflavins by non-aqueous capillary electrophoresis.

Wright LP, Aucamp JP, Apostolides Z.

J Chromatogr A. 2001 Jun 1;919(1):205-13.


Myelin-associated glycoprotein binding to gangliosides. Structural specificity and functional implications.

Schnaar RL, Collins BE, Wright LP, Kiso M, Tropak MB, Roder JC, Crocker PR.

Ann N Y Acad Sci. 1998 Jun 19;845:92-105. Review.


Glutaraldehyde allergy in endoscopy units.

Calder IM, Wright LP, Grimstone D.

Lancet. 1992 Feb 15;339(8790):433. No abstract available.


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