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Recommendations for the Emergency Department Prevention of Sport-Related Concussion.

Bazarian JJ, Raukar N, Devera G, Ellis J, Feden J, Gemme SR, Hafner J, Mannix R, Papa L, Wright DW, Auerbach P; American College of Emergency Physicians Sport-Related Head Injury Prevention Task Force.

Ann Emerg Med. 2019 Jul 17. pii: S0196-0644(19)30444-5. doi: 10.1016/j.annemergmed.2019.05.032. [Epub ahead of print]


The Surgical Intervention for Traumatic Injury Scale: A Clinical Tool for Traumatic Brain Injury.

Sribnick EA, Lunney M, Wright DW, Allen JW, Hudgins PA, Shi J, Wheeler K, Leonard JR, Dhall SS, Xiangh H.

West J Emerg Med. 2019 Jul;20(4):578-584. doi: 10.5811/westjem.2019.4.41802. Epub 2019 Jun 18.


Detection of Single-Nucleotide Polymorphism Markers of Antimalarial Drug Resistance Directly from Whole Blood.

Leelawong M, Adams NM, Gabella WE, Wright DW, Haselton FR.

J Mol Diagn. 2019 Jul;21(4):623-631. doi: 10.1016/j.jmoldx.2019.02.004. Epub 2019 Jun 13.


The effectiveness of hyposaline treatments against host-attached salmon lice.

Sievers M, Oppedal F, Ditria E, Wright DW.

Sci Rep. 2019 May 6;9(1):6976. doi: 10.1038/s41598-019-43533-8.


Application of ESMACS binding free energy protocols to diverse datasets: Bromodomain-containing protein 4.

Wright DW, Wan S, Meyer C, van Vlijmen H, Tresadern G, Coveney PV.

Sci Rep. 2019 Apr 12;9(1):6017. doi: 10.1038/s41598-019-41758-1.


The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) Protocol: a prospective, multi-center, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial.

Hager DN, Hooper MH, Bernard GR, Busse LW, Ely EW, Fowler AA, Gaieski DF, Hall A, Hinson JS, Jackson JC, Kelen GD, Levine M, Lindsell CJ, Malone RE, McGlothlin A, Rothman RE, Viele K, Wright DW, Sevransky JE, Martin GS.

Trials. 2019 Apr 5;20(1):197. doi: 10.1186/s13063-019-3254-2.


Association of Very Early Serum Levels of S100B, Glial Fibrillary Acidic Protein, Ubiquitin C-terminal Hydrolase-L1, and Spectrin Breakdown Product with Outcome in ProTECT III.

Frankel M, Fan L, Yeatts SD, Jeromin A, Vos PE, Wagner AK, Wolf BJ, Pauls Q, Lunney M, Merck LH, Hall CL, Palesch YY, Silbergleit R, Wright DW.

J Neurotrauma. 2019 Jul 9. doi: 10.1089/neu.2018.5809. [Epub ahead of print]


The Effect of Goal-Directed Therapy on Patient Morbidity and Mortality After Traumatic Brain Injury: Results From the Progesterone for the Treatment of Traumatic Brain Injury III Clinical Trial.

Merck LH, Yeatts SD, Silbergleit R, Manley GT, Pauls Q, Palesch Y, Conwit R, Le Roux P, Miller J, Frankel M, Wright DW.

Crit Care Med. 2019 May;47(5):623-631. doi: 10.1097/CCM.0000000000003680.


High-throughput binding affinity calculations at extreme scales.

Dakka J, Turilli M, Wright DW, Zasada SJ, Balasubramanian V, Wan S, Coveney PV, Jha S.

BMC Bioinformatics. 2018 Dec 21;19(Suppl 18):482. doi: 10.1186/s12859-018-2506-6.


Inorganic Complexes and Metal-Based Nanomaterials for Infectious Disease Diagnostics.

Markwalter CF, Kantor AG, Moore CP, Richardson KA, Wright DW.

Chem Rev. 2019 Jan 23;119(2):1456-1518. doi: 10.1021/acs.chemrev.8b00136. Epub 2018 Dec 4.


Emergency department evaluation of the concussed athlete.

Wright DW, Bazarian JJ.

Handb Clin Neurol. 2018;158:81-90. doi: 10.1016/B978-0-444-63954-7.00009-4. Review.


Targeted Imaging of VCAM-1 mRNA in a Mouse Model of Laser-Induced Choroidal Neovascularization Using Antisense Hairpin-DNA-Functionalized Gold-Nanoparticles.

Uddin MI, Kilburn TC, Yang R, McCollum GW, Wright DW, Penn JS.

Mol Pharm. 2018 Dec 3;15(12):5514-5520. doi: 10.1021/acs.molpharmaceut.8b00661. Epub 2018 Oct 29.


Poly(amidoamine)-coated magnetic particles for enhanced detection of Schistosoma circulating anodic antigen in endemic urine samples.

Markwalter CF, Corstjens PLAM, Mammoser CM, Camps G, van Dam GJ, Wright DW.

Analyst. 2018 Dec 17;144(1):212-219. doi: 10.1039/c8an00941d.


Fundus Photography vs. Ophthalmoscopy Outcomes in the Emergency Department (FOTO-ED) Phase III: Web-based, In-service Training of Emergency Providers.

Bruce BB, Bidot S, Hage R, Clough LC, Fajoles-Vasseneix C, Melomed M, Keadey MT, Wright DW, Newman NJ, Biousse V.

Neuroophthalmology. 2018 Jan 26;42(5):269-274. doi: 10.1080/01658107.2017.1419368. eCollection 2018 Oct.


Diagnosis and Management of Mild Traumatic Brain Injury in Children: A Systematic Review.

Lumba-Brown A, Yeates KO, Sarmiento K, Breiding MJ, Haegerich TM, Gioia GA, Turner M, Benzel EC, Suskauer SJ, Giza CC, Joseph M, Broomand C, Weissman B, Gordon W, Wright DW, Moser RS, McAvoy K, Ewing-Cobbs L, Duhaime AC, Putukian M, Holshouser B, Paulk D, Wade SL, Herring SA, Halstead M, Keenan HT, Choe M, Christian CW, Guskiewicz K, Raksin PB, Gregory A, Mucha A, Taylor HG, Callahan JM, DeWitt J, Collins MW, Kirkwood MW, Ragheb J, Ellenbogen RG, Spinks TJ, Ganiats TG, Sabelhaus LJ, Altenhofen K, Hoffman R, Getchius T, Gronseth G, Donnell Z, O'Connor RE, Timmons SD.

JAMA Pediatr. 2018 Nov 1;172(11):e182847. doi: 10.1001/jamapediatrics.2018.2847. Epub 2018 Nov 5.


Centers for Disease Control and Prevention Guideline on the Diagnosis and Management of Mild Traumatic Brain Injury Among Children.

Lumba-Brown A, Yeates KO, Sarmiento K, Breiding MJ, Haegerich TM, Gioia GA, Turner M, Benzel EC, Suskauer SJ, Giza CC, Joseph M, Broomand C, Weissman B, Gordon W, Wright DW, Moser RS, McAvoy K, Ewing-Cobbs L, Duhaime AC, Putukian M, Holshouser B, Paulk D, Wade SL, Herring SA, Halstead M, Keenan HT, Choe M, Christian CW, Guskiewicz K, Raksin PB, Gregory A, Mucha A, Taylor HG, Callahan JM, DeWitt J, Collins MW, Kirkwood MW, Ragheb J, Ellenbogen RG, Spinks TJ, Ganiats TG, Sabelhaus LJ, Altenhofen K, Hoffman R, Getchius T, Gronseth G, Donnell Z, O'Connor RE, Timmons SD.

JAMA Pediatr. 2018 Nov 1;172(11):e182853. doi: 10.1001/jamapediatrics.2018.2853. Epub 2018 Nov 5.


Priorities to Overcome Barriers Impacting Data Science Application in Emergency Care Research.

Puskarich MA, Callaway C, Silbergleit R, Pines JM, Obermeyer Z, Wright DW, Hsia RY, Shah MN, Monte AA, Limkakeng AT Jr, Meisel ZF, Levy PD.

Acad Emerg Med. 2019 Jan;26(1):97-105. doi: 10.1111/acem.13520. Epub 2018 Aug 16.


Evidence for histidine-rich protein 2 immune complex formation in symptomatic patients in Southern Zambia.

Markwalter CF, Mudenda L, Leelawong M, Kimmel DW, Nourani A, Mbambara S, Thuma PE, Wright DW.

Malar J. 2018 Jul 9;17(1):256. doi: 10.1186/s12936-018-2400-8.


Repeated sublethal freshwater exposures reduce the amoebic gill disease parasite, Neoparamoeba perurans, on Atlantic salmon.

Wright DW, Nowak B, Oppedal F, Crosbie P, Stien LH, Dempster T.

J Fish Dis. 2018 Sep;41(9):1403-1410. doi: 10.1111/jfd.12834. Epub 2018 Jun 25.


Structure-activity relationship of new antimalarial 1-aryl-3-susbtituted propanol derivatives: Synthesis, preliminary toxicity profiling, parasite life cycle stage studies, target exploration, and targeted delivery.

Quiliano M, Pabón A, Moles E, Bonilla-Ramirez L, Fabing I, Fong KY, Nieto-Aco DA, Wright DW, Pizarro JC, Vettorazzi A, López de Cerain A, Deharo E, Fernández-Busquets X, Garavito G, Aldana I, Galiano S.

Eur J Med Chem. 2018 May 25;152:489-514. doi: 10.1016/j.ejmech.2018.04.038. Epub 2018 Apr 24.


Emergency Department Implementation of the Centers for Disease Control and Prevention Pediatric Mild Traumatic Brain Injury Guideline Recommendations.

Lumba-Brown A, Wright DW, Sarmiento K, Houry D.

Ann Emerg Med. 2018 Nov;72(5):581-585. doi: 10.1016/j.annemergmed.2018.03.045. Epub 2018 May 10. No abstract available.


A cross-sectional exploratory study of knowledge, attitudes, and practices of emergency health care providers in the assessment of child maltreatment in Maputo, Mozambique.

Pinto L, Lein A, Mahoque R, Wright DW, Sasser SM, Staton CA.

BMC Emerg Med. 2018 May 9;18(1):11. doi: 10.1186/s12873-018-0162-9.


Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2-MPER region.

Flyak AI, Kuzmina N, Murin CD, Bryan C, Davidson E, Gilchuk P, Gulka CP, Ilinykh PA, Shen X, Huang K, Ramanathan P, Turner H, Fusco ML, Lampley R, Kose N, King H, Sapparapu G, Doranz BJ, Ksiazek TG, Wright DW, Saphire EO, Ward AB, Bukreyev A, Crowe JE Jr.

Nat Microbiol. 2018 Jun;3(6):670-677. doi: 10.1038/s41564-018-0157-z. Epub 2018 May 7.


The Dynamics of Concussion: Mapping Pathophysiology, Persistence, and Recovery With Causal-Loop Diagramming.

Kenzie ES, Parks EL, Bigler ED, Wright DW, Lim MM, Chesnutt JC, Hawryluk GWJ, Gordon W, Wakeland W.

Front Neurol. 2018 Apr 4;9:203. doi: 10.3389/fneur.2018.00203. eCollection 2018.


Characterization of Plasmodium Lactate Dehydrogenase and Histidine-Rich Protein 2 Clearance Patterns via Rapid On-Bead Detection from a Single Dried Blood Spot.

Markwalter CF, Gibson LE, Mudenda L, Kimmel DW, Mbambara S, Thuma PE, Wright DW.

Am J Trop Med Hyg. 2018 May;98(5):1389-1396. doi: 10.4269/ajtmh.17-0996. Epub 2018 Mar 15.


A graphical and computational modeling platform for biological pathways.

Livigni A, O'Hara L, Polak ME, Angus T, Wright DW, Smith LB, Freeman TC.

Nat Protoc. 2018 Apr;13(4):705-722. doi: 10.1038/nprot.2017.144. Epub 2018 Mar 15.


Effect of clinical decision rules, patient cost and malpractice information on clinician brain CT image ordering: a randomized controlled trial.

Gimbel RW, Pirrallo RG, Lowe SC, Wright DW, Zhang L, Woo MJ, Fontelo P, Liu F, Connor Z.

BMC Med Inform Decis Mak. 2018 Mar 12;18(1):20. doi: 10.1186/s12911-018-0602-1.


Homelessness and Emergency Medicine: Furthering the Conversation.

Salhi BA, White MH, Pitts SR, Wright DW.

Acad Emerg Med. 2018 May;25(5):597. doi: 10.1111/acem.13391. Epub 2018 Apr 14. No abstract available.


Reply to: Prehospital Intubation: Further Confounders in Trial Results.

Nuño T, Denninghoff KR, Pauls Q, Yeatts SD, Silbergleit R, Palesch YY, Merck LH, Manley G, Wright DW.

Prehosp Emerg Care. 2018 Jul-Aug;22(4):537. doi: 10.1080/10903127.2017.1408729. Epub 2018 Jan 17. No abstract available.


Optic nerve head edema among patients presenting to the emergency department.

Sachdeva V, Vasseneix C, Hage R, Bidot S, Clough LC, Wright DW, Newman NJ, Biousse V, Bruce BB.

Neurology. 2018 Jan 30;90(5):e373-e379. doi: 10.1212/WNL.0000000000004895. Epub 2018 Jan 5.


Homelessness and Emergency Medicine: A Review of the Literature.

Salhi BA, White MH, Pitts SR, Wright DW.

Acad Emerg Med. 2018 May;25(5):577-593. doi: 10.1111/acem.13358. Epub 2018 Jan 11. Review.


The gill parasite Paramoeba perurans compromises aerobic scope, swimming capacity and ion balance in Atlantic salmon.

Hvas M, Karlsbakk E, Mæhle S, Wright DW, Oppedal F.

Conserv Physiol. 2017 Nov 29;5(1):cox066. doi: 10.1093/conphys/cox066. eCollection 2017.


Intracranial Pathology (CT+) in Emergency Department Patients With High GCS and High Standard Assessment of Concussion (SAC) Scores.

Curley KC, OʼNeil BJ, Naunheim R, Wright DW.

J Head Trauma Rehabil. 2018 May/Jun;33(3):E61-E66. doi: 10.1097/HTR.0000000000000355.


Does experience matter? Implications for community consultation for research in emergency settings.

Scicluna VM, Ali MK, Pentz RD, Wright DW, Dickert NW.

AJOB Empir Bioeth. 2017 Apr-Jun;8(2):75-81. doi: 10.1080/23294515.2017.1308978. Epub 2017 Mar 24.


Real-time imaging of VCAM-1 mRNA in TNF-α activated retinal microvascular endothelial cells using antisense hairpin-DNA functionalized gold nanoparticles.

Uddin MI, Jayagopal A, Wong A, McCollum GW, Wright DW, Penn JS.

Nanomedicine. 2018 Jan;14(1):63-71. doi: 10.1016/j.nano.2017.08.018. Epub 2017 Sep 7.


Metal Affinity-Enabled Capture and Release Antibody Reagents Generate a Multiplex Biomarker Enrichment System that Improves Detection Limits of Rapid Diagnostic Tests.

Bauer WS, Gulka CP, Silva-Baucage L, Adams NM, Haselton FR, Wright DW.

Anal Chem. 2017 Oct 3;89(19):10216-10223. doi: 10.1021/acs.analchem.7b01513. Epub 2017 Sep 20.


Plasmodium falciparum HRP2 ELISA for analysis of dried blood spot samples in rural Zambia.

Gibson LE, Markwalter CF, Kimmel DW, Mudenda L, Mbambara S, Thuma PE, Wright DW.

Malar J. 2017 Aug 23;16(1):350. doi: 10.1186/s12936-017-1996-4.


Biolayer interferometry predicts ELISA performance of monoclonal antibody pairs for Plasmodium falciparum histidine-rich protein 2.

Markwalter CF, Jang IK, Burton RA, Domingo GJ, Wright DW.

Anal Biochem. 2017 Oct 1;534:10-13. doi: 10.1016/j.ab.2017.07.010. Epub 2017 Jul 8.


Rapid concentration and elution of malarial antigen histidine-rich protein II using solid phase Zn(II) resin in a simple flow-through pipette tip format.

Bauer WS, Richardson KA, Adams NM, Ricks KM, Gasperino DJ, Ghionea SJ, Rosen M, Nichols KP, Weigl BH, Haselton FR, Wright DW.

Biomicrofluidics. 2017 Jun 2;11(3):034115. doi: 10.1063/1.4984788. eCollection 2017 May.


A Brain Electrical Activity Electroencephalographic-Based Biomarker of Functional Impairment in Traumatic Brain Injury: A Multi-Site Validation Trial.

Hanley D, Prichep LS, Badjatia N, Bazarian J, Chiacchierini R, Curley KC, Garrett J, Jones E, Naunheim R, O'Neil B, O'Neill J, Wright DW, Huff JS.

J Neurotrauma. 2018 Jan 1;35(1):41-47. doi: 10.1089/neu.2017.5004. Epub 2017 Sep 21.


Application of mass transfer theory to biomarker capture by surface functionalized magnetic beads in microcentrifuge tubes.

Scherr TF, Markwalter CF, Bauer WS, Gasperino D, Wright DW, Haselton FR.

Adv Colloid Interface Sci. 2017 Aug;246:275-288. doi: 10.1016/j.cis.2017.02.006. Epub 2017 Feb 17. Review.


Non-linearity of the collagen triple helix in solution and implications for collagen function.

Walker KT, Nan R, Wright DW, Gor J, Bishop AC, Makhatadze GI, Brodsky B, Perkins SJ.

Biochem J. 2017 Jun 16;474(13):2203-2217. doi: 10.1042/BCJ20170217.


Prehospital Intubation is Associated with Favorable Outcomes and Lower Mortality in ProTECT III.

Denninghoff KR, Nuño T, Pauls Q, Yeatts SD, Silbergleit R, Palesch YY, Merck LH, Manley GT, Wright DW.

Prehosp Emerg Care. 2017 Sep-Oct;21(5):539-544. doi: 10.1080/10903127.2017.1315201. Epub 2017 May 10.


'Snorkel' lice barrier technology reduced two co- occurring parasites, the salmon louse (Lepeophtheirus salmonis) and the amoebic gill disease causing agent (Neoparamoeba perurans), in commercial salmon sea-cages.

Wright DW, Stien LH, Dempster T, Vågseth T, Nola V, Fosseidengen JE, Oppedal F.

Prev Vet Med. 2017 May 1;140:97-105. doi: 10.1016/j.prevetmed.2017.03.002. Epub 2017 Mar 10.


Magnetically-enabled biomarker extraction and delivery system: towards integrated ASSURED diagnostic tools.

Bauer WS, Kimmel DW, Adams NM, Gibson LE, Scherr TF, Richardson KA, Conrad JA, Matakala HK, Haselton FR, Wright DW.

Analyst. 2017 May 2;142(9):1569-1580. doi: 10.1039/c7an00278e.


An Ensemble-Based Protocol for the Computational Prediction of Helix-Helix Interactions in G Protein-Coupled Receptors using Coarse-Grained Molecular Dynamics.

Altwaijry NA, Baron M, Wright DW, Coveney PV, Townsend-Nicholson A.

J Chem Theory Comput. 2017 May 9;13(5):2254-2270. doi: 10.1021/acs.jctc.6b01246. Epub 2017 Apr 25.


Impact of individual clinical outcomes on trial participants' perspectives on enrollment in emergency research without consent.

Whitesides LW, Baren JM, Biros MH, Fleischman RJ, Govindarajan PR, Jones EB, Pancioli AM, Pentz RD, Scicluna VM, Wright DW, Dickert NW.

Clin Trials. 2017 Apr;14(2):180-186. doi: 10.1177/1740774516677276. Epub 2016 Nov 15.


Combined Monte Carlo/torsion-angle molecular dynamics for ensemble modeling of proteins, nucleic acids and carbohydrates.

Zhang W, Howell SC, Wright DW, Heindel A, Qiu X, Chen J, Curtis JE.

J Mol Graph Model. 2017 May;73:179-190. doi: 10.1016/j.jmgm.2017.02.010. Epub 2017 Feb 23.


Design and use of mouse control DNA for DNA biomarker extraction and PCR detection from urine: Application for transrenal Mycobacterium tuberculosis DNA detection.

Bordelon H, Ricks KM, Pask ME, Russ PK, Solinas F, Baglia ML, Short PA, Nel A, Blackburn J, Dheda K, Zamudio C, Cáceres T, Wright DW, Haselton FR, Pettit AC.

J Microbiol Methods. 2017 May;136:65-70. doi: 10.1016/j.mimet.2017.02.010. Epub 2017 Mar 9.


Classroom sound can be used to classify teaching practices in college science courses.

Owens MT, Seidel SB, Wong M, Bejines TE, Lietz S, Perez JR, Sit S, Subedar ZS, Acker GN, Akana SF, Balukjian B, Benton HP, Blair JR, Boaz SM, Boyer KE, Bram JB, Burrus LW, Byrd DT, Caporale N, Carpenter EJ, Chan YM, Chen L, Chovnick A, Chu DS, Clarkson BK, Cooper SE, Creech C, Crow KD, de la Torre JR, Denetclaw WF, Duncan KE, Edwards AS, Erickson KL, Fuse M, Gorga JJ, Govindan B, Green LJ, Hankamp PZ, Harris HE, He ZH, Ingalls S, Ingmire PD, Jacobs JR, Kamakea M, Kimpo RR, Knight JD, Krause SK, Krueger LE, Light TL, Lund L, Márquez-Magaña LM, McCarthy BK, McPheron LJ, Miller-Sims VC, Moffatt CA, Muick PC, Nagami PH, Nusse GL, Okimura KM, Pasion SG, Patterson R, Pennings PS, Riggs B, Romeo J, Roy SW, Russo-Tait T, Schultheis LM, Sengupta L, Small R, Spicer GS, Stillman JH, Swei A, Wade JM, Waters SB, Weinstein SL, Willsie JK, Wright DW, Harrison CD, Kelley LA, Trujillo G, Domingo CR, Schinske JN, Tanner KD.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3085-3090. doi: 10.1073/pnas.1618693114. Epub 2017 Mar 6.

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