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The genetic ablation of tau improves long-term, but not short-term, functional outcomes after experimental traumatic brain injury in mice.

Tan XL, Zheng P, Wright DK, Sun M, Brady RD, Liu S, McDonald SJ, Mychasiuk R, Cenap S, Jones NC, O'Brien TJ, Shultz SR.

Brain Inj. 2019 Sep 16:1-9. doi: 10.1080/02699052.2019.1667539. [Epub ahead of print]


Archaeological assessment reveals Earth's early transformation through land use.

Stephens L, Fuller D, Boivin N, Rick T, Gauthier N, Kay A, Marwick B, Armstrong CG, Barton CM, Denham T, Douglass K, Driver J, Janz L, Roberts P, Rogers JD, Thakar H, Altaweel M, Johnson AL, Sampietro Vattuone MM, Aldenderfer M, Archila S, Artioli G, Bale MT, Beach T, Borrell F, Braje T, Buckland PI, Jiménez Cano NG, Capriles JM, Diez Castillo A, Çilingiroğlu Ç, Negus Cleary M, Conolly J, Coutros PR, Covey RA, Cremaschi M, Crowther A, Der L, di Lernia S, Doershuk JF, Doolittle WE, Edwards KJ, Erlandson JM, Evans D, Fairbairn A, Faulkner P, Feinman G, Fernandes R, Fitzpatrick SM, Fyfe R, Garcea E, Goldstein S, Goodman RC, Dalpoim Guedes J, Herrmann J, Hiscock P, Hommel P, Horsburgh KA, Hritz C, Ives JW, Junno A, Kahn JG, Kaufman B, Kearns C, Kidder TR, Lanoë F, Lawrence D, Lee GA, Levin MJ, Lindskoug HB, López-Sáez JA, Macrae S, Marchant R, Marston JM, McClure S, McCoy MD, Miller AV, Morrison M, Motuzaite Matuzeviciute G, Müller J, Nayak A, Noerwidi S, Peres TM, Peterson CE, Proctor L, Randall AR, Renette S, Robbins Schug G, Ryzewski K, Saini R, Scheinsohn V, Schmidt P, Sebillaud P, Seitsonen O, Simpson IA, Sołtysiak A, Speakman RJ, Spengler RN, Steffen ML, Storozum MJ, Strickland KM, Thompson J, Thurston TL, Ulm S, Ustunkaya MC, Welker MH, West C, Williams PR, Wright DK, Wright N, Zahir M, Zerboni A, Beaudoin E, Munevar Garcia S, Powell J, Thornton A, Kaplan JO, Gaillard MJ, Klein Goldewijk K, Ellis E.

Science. 2019 Aug 30;365(6456):897-902. doi: 10.1126/science.aax1192.


Thinking about strengths in end-of-life nursing practice: the case of intensive care unit nurses.

Vanderspank-Wright B, Wright DK, McMillan K.

Int J Palliat Nurs. 2019 Aug 2;25(8):378-385. doi: 10.12968/ijpn.2019.25.8.378.


Tranexamic acid modulates the cellular immune profile after traumatic brain injury in mice without hyperfibrinolysis.

Draxler DF, Daglas M, Fernando A, Hanafi G, McCutcheon F, Ho H, Galle A, Gregory J, Larsson P, Keragala C, Wright DK, Tavancheh E, Au AE, Niego B, Wilson K, Plebanski M, Sashindranath M, Medcalf RL.

J Thromb Haemost. 2019 Aug 8. doi: 10.1111/jth.14603. [Epub ahead of print]


Aged rats have an altered immune response and worse outcomes after traumatic brain injury.

Sun M, Brady RD, Casillas-Espinosa PM, Wright DK, Semple BD, Kim HA, Mychasiuk R, Sobey CG, O'Brien TJ, Vinh A, McDonald SJ, Shultz SR.

Brain Behav Immun. 2019 Aug;80:536-550. doi: 10.1016/j.bbi.2019.04.038. Epub 2019 Apr 27.


Meaningful experiences and end-of-life care in the intensive care unit: A qualitative study.

Stokes H, Vanderspank-Wright B, Fothergill Bourbonnais F, Wright DK.

Intensive Crit Care Nurs. 2019 Aug;53:1-7. doi: 10.1016/j.iccn.2019.03.010. Epub 2019 Apr 6.


Coping with moral distress - The experiences of intensive care nurses: An interpretive descriptive study.

Forozeiya D, Vanderspank-Wright B, Bourbonnais FF, Moreau D, Wright DK.

Intensive Crit Care Nurs. 2019 Aug;53:23-29. doi: 10.1016/j.iccn.2019.03.002. Epub 2019 Apr 1.


Towards a Guiding Framework for Prison Palliative Care Nursing Ethics.

Hudson H, Wright DK.

ANS Adv Nurs Sci. 2019 Mar 1. doi: 10.1097/ANS.0000000000000266. [Epub ahead of print]


Health Professional-Identified Barriers to Living Donor Kidney Transplantation: A Qualitative Study.

Sandal S, Charlebois K, Fiore JF Jr, Wright DK, Fortin MC, Feldman LS, Alam A, Weber C.

Can J Kidney Health Dis. 2019 Feb 13;6:2054358119828389. doi: 10.1177/2054358119828389. eCollection 2019.


Diffusion MRI abnormalities in adolescent rats given repeated mild traumatic brain injury.

Wortman RC, Meconi A, Neale KJ, Brady RD, McDonald SJ, Christie BR, Wright DK, Shultz SR.

Ann Clin Transl Neurol. 2018 Oct 17;5(12):1588-1598. doi: 10.1002/acn3.667. eCollection 2018 Dec.


A Scoping Review to Map Empirical Evidence Regarding Key Domains and Questions in the Clinical Pathway of Delirium in Palliative Care.

Lawlor PG, Rutkowski NA, MacDonald AR, Ansari MT, Sikora L, Momoli F, Kanji S, Wright DK, Rosenberg E, Hosie A, Pereira JL, Meagher D, Rice J, Scott J, Bush SH.

J Pain Symptom Manage. 2019 Mar;57(3):661-681.e12. doi: 10.1016/j.jpainsymman.2018.12.002. Epub 2018 Dec 12.


Elimination of vesicular zinc alters the behavioural and neuroanatomical effects of social defeat stress in mice.

McAllister BB, Wright DK, Wortman RC, Shultz SR, Dyck RH.

Neurobiol Stress. 2018 Oct 22;9:199-213. doi: 10.1016/j.ynstr.2018.10.003. eCollection 2018 Nov.


Of dilemmas and tensions: a qualitative study of palliative care physicians' positions regarding voluntary active euthanasia in Quebec, Canada.

Bélanger E, Towers A, Wright DK, Chen Y, Tradounsky G, Macdonald ME.

J Med Ethics. 2019 Jan;45(1):48-53. doi: 10.1136/medethics-2017-104339. Epub 2018 Oct 30.


Personhood: An evolutionary concept analysis for nursing ethics, theory, practice, and research.

Sofronas M, Wright DK, Carnevale FA.

Nurs Forum. 2018 Oct;53(4):406-415. doi: 10.1111/nuf.12267. Epub 2018 Jun 27. Review.


Transactive Response DNA-Binding Protein 43 Abnormalities after Traumatic Brain Injury.

Tan XL, Sun M, Brady RD, Liu S, Llanos R, Cheung S, Wright DK, Casillas-Espinosa PM, Sashindranath M, O'Brien TJ, McDonald SJ, Turner BJ, Shultz SR.

J Neurotrauma. 2018 Aug 10. doi: 10.1089/neu.2017.5491. [Epub ahead of print]


Telomere length and advanced diffusion MRI as biomarkers for repetitive mild traumatic brain injury in adolescent rats.

Wright DK, O'Brien TJ, Mychasiuk R, Shultz SR.

Neuroimage Clin. 2018 Jan 31;18:315-324. doi: 10.1016/j.nicl.2018.01.033. eCollection 2018.


Dead on the table: A theoretical expansion of the vicarious trauma that operating room clinicians experience when their patients die.

Hartley H, Wright DK, Vanderspank-Wright B, Grassau P, Murray MA.

Death Stud. 2019;43(5):301-310. doi: 10.1080/07481187.2018.1461711. Epub 2018 Sep 25.


Repeated mild traumatic brain injury can cause acute neurologic impairment without overt structural damage in juvenile rats.

Meconi A, Wortman RC, Wright DK, Neale KJ, Clarkson M, Shultz SR, Christie BR.

PLoS One. 2018 May 8;13(5):e0197187. doi: 10.1371/journal.pone.0197187. eCollection 2018.


Relational ethics of delirium care: Findings from a hospice ethnography.

Wright DK, Brajtman S, Macdonald ME.

Nurs Inq. 2018 Jul;25(3):e12234. doi: 10.1111/nin.12234. Epub 2018 Mar 24.


Nursing memes at odds with our values.

Wright DK.

Can Nurse. 2017 Mar-Apr;113(2):44. No abstract available.


Oculomotor Cognitive Control Abnormalities in Australian Rules Football Players with a History of Concussion.

Clough M, Mutimer S, Wright DK, Tsang A, Costello DM, Gardner AJ, Stanwell P, Mychasiuk R, Sun M, Brady RD, McDonald SJ, Webster KM, Johnstone MR, Semple BD, Agoston DV, White OB, Frayne R, Fielding J, O'Brien TJ, Shultz SR.

J Neurotrauma. 2018 Mar 1;35(5):730-738. doi: 10.1089/neu.2017.5204. Epub 2018 Feb 9.


Sex matters: repetitive mild traumatic brain injury in adolescent rats.

Wright DK, O'Brien TJ, Shultz SR, Mychasiuk R.

Ann Clin Transl Neurol. 2017 Jul 26;4(9):640-654. doi: 10.1002/acn3.441. eCollection 2017 Sep.


Forensic nursing and the palliative approach to care: an empirical nursing ethics analysis.

Wright DK, Vanderspank-Wright B, Holmes D, Skinner E.

Int J Palliat Nurs. 2017 Aug 2;23(8):378-385. doi: 10.12968/ijpn.2017.23.8.378.


Treatment with an interleukin-1 receptor antagonist mitigates neuroinflammation and brain damage after polytrauma.

Sun M, Brady RD, Wright DK, Kim HA, Zhang SR, Sobey CG, Johnstone MR, O'Brien TJ, Semple BD, McDonald SJ, Shultz SR.

Brain Behav Immun. 2017 Nov;66:359-371. doi: 10.1016/j.bbi.2017.08.005. Epub 2017 Aug 3.


Interleukin-1 Receptor in Seizure Susceptibility after Traumatic Injury to the Pediatric Brain.

Semple BD, O'Brien TJ, Gimlin K, Wright DK, Kim SE, Casillas-Espinosa PM, Webster KM, Petrou S, Noble-Haeusslein LJ.

J Neurosci. 2017 Aug 16;37(33):7864-7877. doi: 10.1523/JNEUROSCI.0982-17.2017. Epub 2017 Jul 19.


Differences in white matter structure between seizure prone (FAST) and seizure resistant (SLOW) rat strains.

Sharma P, Wright DK, Johnston LA, Powell KL, Wlodek ME, Shultz SR, O'Brien TJ, Gilby KL.

Neurobiol Dis. 2017 Aug;104:33-40. doi: 10.1016/j.nbd.2017.04.022. Epub 2017 May 1.


Hospital rules and regulations: The perspectives of youth receiving psychiatric care.

Gros CP, Parr C, Wright DK, Montreuil M, Frechette J.

J Child Adolesc Psychiatr Nurs. 2017 Feb;30(1):18-24. doi: 10.1111/jcap.12166. Epub 2017 May 2.


Changes in Apparent Fiber Density and Track-Weighted Imaging Metrics in White Matter following Experimental Traumatic Brain Injury.

Wright DK, Johnston LA, Kershaw J, Ordidge R, O'Brien TJ, Shultz SR.

J Neurotrauma. 2017 Jul 1;34(13):2109-2118. doi: 10.1089/neu.2016.4730. Epub 2017 Apr 13.


Engaging with patients who desire death: Interpretation, presence, and constraint.

Wright DK, Chirchikova M, Daniel V, Bitzas V, Elmore J, Fortin ML.

Can Oncol Nurs J. 2017 Feb 1;27(1):56-64. doi: 10.5737/236880762715664. eCollection 2017 Winter.


S’engager auprès des patients qui veulent mourir : interprétation, présence et contrainte.

Wright DK, Chirchikova M, Daniel V, Bitzas V, Elmore J, Fortin ML.

Can Oncol Nurs J. 2017 Feb 1;27(1):65-73. doi: 10.5737/236880762716573. eCollection 2017 Winter. French. No abstract available.

Free PMC Article

Nurses' moral experiences of assisted death: A meta-synthesis of qualitative research.

Elmore J, Wright DK, Paradis M.

Nurs Ethics. 2018 Dec;25(8):955-972. doi: 10.1177/0969733016679468. Epub 2016 Dec 28.


Dual-modality NIRF-MRI cubosomes and hexosomes: High throughput formulation and in vivo biodistribution.

Tran N, Bye N, Moffat BA, Wright DK, Cuddihy A, Hinton TM, Hawley AM, Reynolds NP, Waddington LJ, Mulet X, Turnley AM, Morganti-Kossmann MC, Muir BW.

Mater Sci Eng C Mater Biol Appl. 2017 Feb 1;71:584-593. doi: 10.1016/j.msec.2016.10.028. Epub 2016 Oct 17.


Suffering and medicalization at the end of life: The case of physician-assisted dying.

Karsoho H, Fishman JR, Wright DK, Macdonald ME.

Soc Sci Med. 2016 Dec;170:188-196. doi: 10.1016/j.socscimed.2016.10.010. Epub 2016 Oct 12.


Traumatic Brain Injury Results in Cellular, Structural and Functional Changes Resembling Motor Neuron Disease.

Wright DK, Liu S, van der Poel C, McDonald SJ, Brady RD, Taylor L, Yang L, Gardner AJ, Ordidge R, O'Brien TJ, Johnston LA, Shultz SR.

Cereb Cortex. 2017 Sep 1;27(9):4503-4515. doi: 10.1093/cercor/bhw254.


Behavioral, blood, and magnetic resonance imaging biomarkers of experimental mild traumatic brain injury.

Wright DK, Trezise J, Kamnaksh A, Bekdash R, Johnston LA, Ordidge R, Semple BD, Gardner AJ, Stanwell P, O'Brien TJ, Agoston DV, Shultz SR.

Sci Rep. 2016 Jun 28;6:28713. doi: 10.1038/srep28713.


Sodium selenate retards epileptogenesis in acquired epilepsy models reversing changes in protein phosphatase 2A and hyperphosphorylated tau.

Liu SJ, Zheng P, Wright DK, Dezsi G, Braine E, Nguyen T, Corcoran NM, Johnston LA, Hovens CM, Mayo JN, Hudson M, Shultz SR, Jones NC, O'Brien TJ.

Brain. 2016 Jul;139(Pt 7):1919-38. doi: 10.1093/brain/aww116. Epub 2016 Jun 11.


Sodium selenate, a protein phosphatase 2A activator, mitigates hyperphosphorylated tau and improves repeated mild traumatic brain injury outcomes.

Tan XL, Wright DK, Liu S, Hovens C, O'Brien TJ, Shultz SR.

Neuropharmacology. 2016 Sep;108:382-93. doi: 10.1016/j.neuropharm.2016.05.001. Epub 2016 May 7.


Progesterone treatment reduces neuroinflammation, oxidative stress and brain damage and improves long-term outcomes in a rat model of repeated mild traumatic brain injury.

Webster KM, Wright DK, Sun M, Semple BD, Ozturk E, Stein DG, O'Brien TJ, Shultz SR.

J Neuroinflammation. 2015 Dec 18;12:238. doi: 10.1186/s12974-015-0457-7.


Physicians and euthanasia: a Canadian print-media discourse analysis of physician perspectives.

Wright DK, Fishman JR, Karsoho H, Sandham S, Macdonald ME.

CMAJ Open. 2015 Apr 2;3(2):E134-9. doi: 10.9778/cmajo.20140071. eCollection 2015 Apr-Jun.


Community palliative care use by dementia sufferers may reduce emergency department use at end of life.

Wright DK, Vandyk AD.

Evid Based Nurs. 2016 Jan;19(1):29. doi: 10.1136/eb-2015-102122. Epub 2015 Sep 16. No abstract available.


A Comprehensive Atlas of the Adult Mouse Penis.

Phillips TR, Wright DK, Gradie PE, Johnston LA, Pask AJ.

Sex Dev. 2015;9(3):162-72. doi: 10.1159/000431010. Epub 2015 Jun 19.


A preliminary video analysis of concussion in the National Rugby League.

Gardner AJ, Iverson GL, Quinn TN, Makdissi M, Levi CR, Shultz SR, Wright DK, Stanwell P.

Brain Inj. 2015 Sep;29(10):1182-1185. doi: 10.3109/02699052.2015.1034179. Epub 2015 Jun 17.


Delirium as letting go: An ethnographic analysis of hospice care and family moral experience.

Wright DK, Brajtman S, Cragg B, Macdonald ME.

Palliat Med. 2015 Dec;29(10):959-66. doi: 10.1177/0269216315580742. Epub 2015 Apr 8.


Tibial fracture exacerbates traumatic brain injury outcomes and neuroinflammation in a novel mouse model of multitrauma.

Shultz SR, Sun M, Wright DK, Brady RD, Liu S, Beynon S, Schmidt SF, Kaye AH, Hamilton JA, O'Brien TJ, Grills BL, McDonald SJ.

J Cereb Blood Flow Metab. 2015 Aug;35(8):1339-47. doi: 10.1038/jcbfm.2015.56. Epub 2015 Apr 8.


Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury.

Shultz SR, Wright DK, Zheng P, Stuchbery R, Liu SJ, Sashindranath M, Medcalf RL, Johnston LA, Hovens CM, Jones NC, O'Brien TJ.

Brain. 2015 May;138(Pt 5):1297-313. doi: 10.1093/brain/awv053. Epub 2015 Mar 13.


Experimental Traumatic Brain Injury Results in Long-Term Recovery of Functional Responsiveness in Sensory Cortex but Persisting Structural Changes and Sensorimotor, Cognitive, and Emotional Deficits.

Johnstone VP, Wright DK, Wong K, O'Brien TJ, Rajan R, Shultz SR.

J Neurotrauma. 2015 Sep 1;32(17):1333-46. doi: 10.1089/neu.2014.3785. Epub 2015 May 14.


Experimental Traumatic Brain Injury Induces Bone Loss in Rats.

Brady RD, Shultz SR, Sun M, Romano T, van der Poel C, Wright DK, Wark JD, O'Brien TJ, Grills BL, McDonald SJ.

J Neurotrauma. 2016 Dec 1;33(23):2154-2160. Epub 2016 Oct 24.


Analysis of feature intervisibility and cumulative visibility using GIS, Bayesian and spatial statistics: a study from the Mandara Mountains, northern Cameroon.

Wright DK, MacEachern S, Lee J.

PLoS One. 2014 Nov 10;9(11):e112191. doi: 10.1371/journal.pone.0112191. eCollection 2014.


Nitroxide-loaded hexosomes provide MRI contrast in vivo.

Bye N, Hutt OE, Hinton TM, Acharya DP, Waddington LJ, Moffat BA, Wright DK, Wang HX, Mulet X, Muir BW.

Langmuir. 2014 Jul 29;30(29):8898-906. doi: 10.1021/la5007296. Epub 2014 Jul 14.


End-of-life delirium: issues regarding recognition, optimal management, and the role of sedation in the dying phase.

Bush SH, Leonard MM, Agar M, Spiller JA, Hosie A, Wright DK, Meagher DJ, Currow DC, Bruera E, Lawlor PG.

J Pain Symptom Manage. 2014 Aug;48(2):215-30. doi: 10.1016/j.jpainsymman.2014.05.009. Epub 2014 May 28. Review.


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