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Items: 1 to 50 of 190

1.

Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism.

Krah NM, Narayanan SM, Yugawa DE, Straley JA, Wright CVE, MacDonald RJ, Murtaugh LC.

Dev Cell. 2019 Sep 23;50(6):744-754.e4. doi: 10.1016/j.devcel.2019.07.012. Epub 2019 Aug 15.

PMID:
31422917
2.

Differential Cell Susceptibilities to KrasG12D in the Setting of Obstructive Chronic Pancreatitis.

Shi C, Pan FC, Kim JN, Washington MK, Padmanabhan C, Meyer CT, Kopp JL, Sander M, Gannon M, Beauchamp RD, Wright CV, Means AL.

Cell Mol Gastroenterol Hepatol. 2019 Jul 13. pii: S2352-345X(19)30088-8. doi: 10.1016/j.jcmgh.2019.07.001. [Epub ahead of print]

3.

Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells.

Trogden KP, Zhu X, Lee JS, Wright CVE, Gu G, Kaverina I.

Curr Biol. 2019 Jul 22;29(14):2339-2350.e5. doi: 10.1016/j.cub.2019.06.032. Epub 2019 Jul 11.

PMID:
31303487
4.

The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function.

Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R.

Diabetes. 2019 Sep;68(9):1806-1818. doi: 10.2337/db19-0349. Epub 2019 Jun 14.

PMID:
31201281
5.

Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis.

Wen HJ, Gao S, Wang Y, Ray M, Magnuson MA, Wright CVE, Di Magliano MP, Frankel TL, Crawford HC.

Cell Mol Gastroenterol Hepatol. 2019;8(2):173-192. doi: 10.1016/j.jcmgh.2019.05.006. Epub 2019 May 21.

6.

Keeping psychologists in the driver's seat: Four perspectives on quality improvement and clinical data registries.

Rousmaniere T, Wright CV, Boswell J, Constantino MJ, Castonguay L, McLeod J, Pedulla D, Nordal K.

Psychotherapy (Chic). 2019 May 23. doi: 10.1037/pst0000227. [Epub ahead of print]

PMID:
31120268
7.

Promoting measurement-based care and quality measure development: The APA mental and behavioral health registry initiative.

Wright CV, Goodheart C, Bard D, Bobbitt BL, Butt Z, Lysell K, McKay D, Stephens K.

Psychol Serv. 2019 Apr 25. doi: 10.1037/ser0000347. [Epub ahead of print]

PMID:
31021113
8.

Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue.

Prentice BM, Hart NJ, Phillips N, Haliyur R, Judd A, Armandala R, Spraggins JM, Lowe CL, Boyd KL, Stein RW, Wright CV, Norris JL, Powers AC, Brissova M, Caprioli RM.

Diabetologia. 2019 Jun;62(6):1036-1047. doi: 10.1007/s00125-019-4855-8. Epub 2019 Apr 6.

PMID:
30955045
9.

Point mutations in the PDX1 transactivation domain impair human β-cell development and function.

Wang X, Sterr M, Ansarullah, Burtscher I, Böttcher A, Beckenbauer J, Siehler J, Meitinger T, Häring HU, Staiger H, Cernilogar FM, Schotta G, Irmler M, Beckers J, Wright CVE, Bakhti M, Lickert H.

Mol Metab. 2019 Jun;24:80-97. doi: 10.1016/j.molmet.2019.03.006. Epub 2019 Mar 20.

10.

ROCK-nmMyoII, Notch and Neurog3 gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche.

Bankaitis ED, Bechard ME, Gu G, Magnuson MA, Wright CVE.

Development. 2018 Sep 21;145(18). pii: dev162115. doi: 10.1242/dev.162115.

11.

The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis.

Tsuda M, Fukuda A, Roy N, Hiramatsu Y, Leonhardt L, Kakiuchi N, Hoyer K, Ogawa S, Goto N, Ikuta K, Kimura Y, Matsumoto Y, Takada Y, Yoshioka T, Maruno T, Yamaga Y, Kim GE, Akiyama H, Ogawa S, Wright CV, Saur D, Takaori K, Uemoto S, Hebrok M, Chiba T, Seno H.

J Clin Invest. 2018 Aug 1;128(8):3475-3489. doi: 10.1172/JCI94287. Epub 2018 Jul 16.

12.

Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact.

Ray TA, Roy S, Kozlowski C, Wang J, Cafaro J, Hulbert SW, Wright CV, Field GD, Kay JN.

Elife. 2018 Apr 3;7. pii: e34241. doi: 10.7554/eLife.34241.

13.

ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.

Kimura Y, Fukuda A, Ogawa S, Maruno T, Takada Y, Tsuda M, Hiramatsu Y, Araki O, Nagao M, Yoshikawa T, Ikuta K, Yoshioka T, Wang Z, Akiyama H, Wright CV, Takaori K, Uemoto S, Chiba T, Seno H.

Gastroenterology. 2018 Jul;155(1):194-209.e2. doi: 10.1053/j.gastro.2018.03.039. Epub 2018 Mar 29.

PMID:
29604291
14.

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.

Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, Staiger H, Häring HU, Lederer G, Meitinger T, Cernilogar FM, Schotta G, Irmler M, Beckers J, Hrabě de Angelis M, Ray M, Wright CVE, Bakhti M, Lickert H.

Mol Metab. 2018 Mar;9:57-68. doi: 10.1016/j.molmet.2018.01.011. Epub 2018 Jan 31.

15.

Student perceptions of digital badges in a drug information and literature evaluation course.

Fajiculay JR, Parikh BT, Wright CV, Sheehan AH.

Curr Pharm Teach Learn. 2017 Sep;9(5):881-886. doi: 10.1016/j.cptl.2017.05.013. Epub 2017 Jul 1.

PMID:
29233319
16.

Erratum: EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity.

Löf-Öhlin ZM, Nyeng P, Bechard ME, Hess K, Bankaitis E, Greiner TU, Ameri J, Wright CV, Semb H.

Nat Cell Biol. 2017 Nov 29;19(12):1442. doi: 10.1038/ncb3646.

PMID:
29184175
17.

EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity.

Löf-Öhlin ZM, Nyeng P, Bechard ME, Hess K, Bankaitis E, Greiner TU, Ameri J, Wright CV, Semb H.

Nat Cell Biol. 2017 Nov;19(11):1313-1325. doi: 10.1038/ncb3628. Epub 2017 Oct 23. Erratum in: Nat Cell Biol. 2017 Nov 29;19(12 ):1442.

PMID:
29058721
18.

A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry.

Zhang J, Weinrich JAP, Russ JB, Comer JD, Bommareddy PK, DiCasoli RJ, Wright CVE, Li Y, van Roessel PJ, Kaltschmidt JA.

Cell Rep. 2017 Oct 17;21(3):666-678. doi: 10.1016/j.celrep.2017.09.079.

19.

Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis.

Larsen HL, Martín-Coll L, Nielsen AV, Wright CVE, Trusina A, Kim YH, Grapin-Botton A.

Nat Commun. 2017 Sep 19;8(1):605. doi: 10.1038/s41467-017-00258-4.

20.

FUCCI tracking shows cell-cycle-dependent Neurog3 variation in pancreatic progenitors.

Bechard ME, Bankaitis ED, Ustione A, Piston DW, Magnuson MA, Wright CVE.

Genesis. 2017 Sep;55(9). doi: 10.1002/dvg.23050.

21.

c-Myc downregulation is required for preacinar to acinar maturation and pancreatic homeostasis.

Sánchez-Arévalo Lobo VJ, Fernández LC, Carrillo-de-Santa-Pau E, Richart L, Cobo I, Cendrowski J, Moreno U, Del Pozo N, Megías D, Bréant B, Wright CV, Magnuson M, Real FX.

Gut. 2018 Apr;67(4):707-718. doi: 10.1136/gutjnl-2016-312306. Epub 2017 Feb 3.

PMID:
28159836
22.

PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.

Roy N, Takeuchi KK, Ruggeri JM, Bailey P, Chang D, Li J, Leonhardt L, Puri S, Hoffman MT, Gao S, Halbrook CJ, Song Y, Ljungman M, Malik S, Wright CV, Dawson DW, Biankin AV, Hebrok M, Crawford HC.

Genes Dev. 2016 Dec 15;30(24):2669-2683. doi: 10.1101/gad.291021.116.

23.

The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.

Yang YP, Magnuson MA, Stein R, Wright CV.

Development. 2017 Jan 15;144(2):248-257. doi: 10.1242/dev.143123. Epub 2016 Dec 19.

24.

New ideas connecting the cell cycle and pancreatic endocrine-lineage specification.

Bechard ME, Wright CV.

Cell Cycle. 2017 Feb 16;16(4):301-303. doi: 10.1080/15384101.2016.1256149. Epub 2016 Nov 18. No abstract available.

25.

Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A.

Hoang CQ, Hale MA, Azevedo-Pouly AC, Elsässer HP, Deering TG, Willet SG, Pan FC, Magnuson MA, Wright CV, Swift GH, MacDonald RJ.

Mol Cell Biol. 2016 Nov 28;36(24):3033-3047. Print 2016 Dec 15.

26.

Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells.

Bechard ME, Bankaitis ED, Hipkens SB, Ustione A, Piston DW, Yang YP, Magnuson MA, Wright CV.

Genes Dev. 2016 Aug 15;30(16):1852-65. doi: 10.1101/gad.284729.116. Epub 2016 Sep 1.

27.

Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.

Henley KD, Stanescu DE, Kropp PA, Wright CVE, Won KJ, Stoffers DA, Gannon M.

Cell Rep. 2016 Jun 21;15(12):2637-2650. doi: 10.1016/j.celrep.2016.05.040. Epub 2016 Jun 9.

28.

Foxl1-expressing mesenchymal cells constitute the intestinal stem cell niche.

Aoki R, Shoshkes-Carmel M, Gao N, Shin S, May CL, Golson ML, Zahm AM, Ray M, Wiser CL, Wright CV, Kaestner KH.

Cell Mol Gastroenterol Hepatol. 2016 Feb 1;2(2):175-188.

29.

Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice.

Kodama S, Nakano Y, Hirata K, Furuyama K, Horiguchi M, Kuhara T, Masui T, Kawaguchi M, Gannon M, Wright CV, Uemoto S, Kawaguchi Y.

Sci Rep. 2016 Feb 18;6:21211. doi: 10.1038/srep21211.

30.
31.

Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche.

Bankaitis ED, Bechard ME, Wright CV.

Genes Dev. 2015 Oct 15;29(20):2203-16. doi: 10.1101/gad.267914.115.

32.

Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3.

Comer JD, Pan FC, Willet SG, Haldipur P, Millen KJ, Wright CV, Kaltschmidt JA.

Front Neural Circuits. 2015 Jul 23;9:36. doi: 10.3389/fncir.2015.00036. eCollection 2015.

33.

The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.

Krah NM, De La O JP, Swift GH, Hoang CQ, Willet SG, Chen Pan F, Cash GM, Bronner MP, Wright CV, MacDonald RJ, Murtaugh LC.

Elife. 2015 Jul 7;4. doi: 10.7554/eLife.07125.

34.

PDX1 binds and represses hepatic genes to ensure robust pancreatic commitment in differentiating human embryonic stem cells.

Teo AK, Tsuneyoshi N, Hoon S, Tan EK, Stanton LW, Wright CV, Dunn NR.

Stem Cell Reports. 2015 Apr 14;4(4):578-90. doi: 10.1016/j.stemcr.2015.02.015. Epub 2015 Apr 2.

35.

Disrupting Foxh1-Groucho interaction reveals robustness of nodal-based embryonic patterning.

Halstead AM, Wright CV.

Mech Dev. 2015 May;136:155-65. doi: 10.1016/j.mod.2014.12.002. Epub 2014 Dec 12.

36.

Dominant and context-specific control of endodermal organ allocation by Ptf1a.

Willet SG, Hale MA, Grapin-Botton A, Magnuson MA, MacDonald RJ, Wright CV.

Development. 2014 Nov;141(22):4385-94. doi: 10.1242/dev.114165.

37.

Partial duct ligation: β-cell proliferation and beyond.

Van de Casteele M, Leuckx G, Cai Y, Yuchi Y, Coppens V, De Groef S, Van Gassen N, Baeyens L, Heremans Y, Wright CV, Heimberg H.

Diabetes. 2014 Aug;63(8):2567-77. doi: 10.2337/db13-0831. No abstract available.

38.

Symmetry breakage in the vertebrate embryo: when does it happen and how does it work?

Blum M, Schweickert A, Vick P, Wright CV, Danilchik MV.

Dev Biol. 2014 Sep 1;393(1):109-23. doi: 10.1016/j.ydbio.2014.06.014. Epub 2014 Jun 24. Review.

39.

Left-right asymmetry: advances and enigmas.

Halpern ME, Hobert O, Wright CV.

Genesis. 2014 Jun;52(6):451-4. doi: 10.1002/dvg.22791. No abstract available.

PMID:
24943067
40.

Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding.

Reinert RB, Cai Q, Hong JY, Plank JL, Aamodt K, Prasad N, Aramandla R, Dai C, Levy SE, Pozzi A, Labosky PA, Wright CV, Brissova M, Powers AC.

Development. 2014 Apr;141(7):1480-91. doi: 10.1242/dev.098657. Epub 2014 Feb 26.

41.

Temporal identity transition from Purkinje cell progenitors to GABAergic interneuron progenitors in the cerebellum.

Seto Y, Nakatani T, Masuyama N, Taya S, Kumai M, Minaki Y, Hamaguchi A, Inoue YU, Inoue T, Miyashita S, Fujiyama T, Yamada M, Chapman H, Campbell K, Magnuson MA, Wright CV, Kawaguchi Y, Ikenaka K, Takebayashi H, Ishiwata S, Ono Y, Hoshino M.

Nat Commun. 2014;5:3337. doi: 10.1038/ncomms4337.

42.

Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice.

Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stangé G, Shemer R, Nord C, Scheel DW, Pan FC, Ahlgren U, Gu G, Stoffers DA, Dor Y, Ferrer J, Gradwohl G, Wright CV, Van de Casteele M, German MS, Bouwens L, Heimberg H.

Nat Biotechnol. 2014 Jan;32(1):76-83. doi: 10.1038/nbt.2747. Epub 2013 Nov 17.

43.

Identification and manipulation of biliary metaplasia in pancreatic tumors.

Delgiorno KE, Hall JC, Takeuchi KK, Pan FC, Halbrook CJ, Washington MK, Olive KP, Spence JR, Sipos B, Wright CV, Wells JM, Crawford HC.

Gastroenterology. 2014 Jan;146(1):233-44.e5. doi: 10.1053/j.gastro.2013.08.053. Epub 2013 Aug 30.

44.

Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.

Sugiyama T, Benitez CM, Ghodasara A, Liu L, McLean GW, Lee J, Blauwkamp TA, Nusse R, Wright CV, Gu G, Kim SK.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12691-6. doi: 10.1073/pnas.1304507110. Epub 2013 Jul 12.

45.

PDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation.

Guo L, Inada A, Aguayo-Mazzucato C, Hollister-Lock J, Fujitani Y, Weir GC, Wright CV, Sharma A, Bonner-Weir S.

Diabetes. 2013 Oct;62(10):3459-68. doi: 10.2337/db12-1833. Epub 2013 Jun 17.

46.

Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb.

Lancman JJ, Zvenigorodsky N, Gates KP, Zhang D, Solomon K, Humphrey RK, Kuo T, Setiawan L, Verkade H, Chi YI, Jhala US, Wright CV, Stainier DY, Dong PD.

Development. 2013 Jul;140(13):2669-79. doi: 10.1242/dev.090993. Epub 2013 May 29.

47.

Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation.

von Figura G, Morris JP 4th, Wright CV, Hebrok M.

Gut. 2014 Apr;63(4):656-64. doi: 10.1136/gutjnl-2012-304287. Epub 2013 May 3.

48.

The evaluation of sexual harassment litigants: reducing discrepancies in the diagnosis of posttraumatic stress disorder.

Lawson AK, Wright CV, Fitzgerald LF.

Law Hum Behav. 2013 Oct;37(5):337-347. doi: 10.1037/lhb0000024. Epub 2013 Apr 1.

PMID:
23544390
49.

Non-parallel recombination limits Cre-LoxP-based reporters as precise indicators of conditional genetic manipulation.

Liu J, Willet SG, Bankaitis ED, Xu Y, Wright CV, Gu G.

Genesis. 2013 Jun;51(6):436-42. doi: 10.1002/dvg.22384. Epub 2013 Mar 26.

50.

Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration.

Pan FC, Bankaitis ED, Boyer D, Xu X, Van de Casteele M, Magnuson MA, Heimberg H, Wright CV.

Development. 2013 Feb;140(4):751-64. doi: 10.1242/dev.090159. Epub 2013 Jan 16.

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