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On the power to detect rare recombination events.

Wright AE, Darolti I, Bloch NI, Oostra V, Sandkam BA, Buechel SD, Kolm N, Breden F, Vicoso B, Mank JE.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12607-12608. doi: 10.1073/pnas.1905555116. Epub 2019 Jun 18. No abstract available.


Distinguishing logopenic from semantic & nonfluent variant primary progressive aphasia: Patterns of linguistic and behavioral correlations.

Keator LM, Wright AE, Saxena S, Kim K, Demsky C, Sebastian R, Sheppard SM, Breining B, Hillis AE, Tippett DC.

Neurocase. 2019 Jun 4:1-8. doi: 10.1080/13554794.2019.1625929. [Epub ahead of print]


Phenotypic sexual dimorphism is associated with genomic signatures of resolved sexual conflict.

Wright AE, Rogers TF, Fumagalli M, Cooney CR, Mank JE.

Mol Ecol. 2019 Apr 30. doi: 10.1111/mec.15115. [Epub ahead of print]


Educational Models for the Re-Establishment of Dental Therapy Education in Canada.

Sunell S, Wright AE, Udahl BK, Benbow P.

J Dent Educ. 2019 Apr 8. doi: 10.21815/JDE.019.085. [Epub ahead of print]


ngsLD: evaluating linkage disequilibrium using genotype likelihoods.

Fox EA, Wright AE, Fumagalli M, Vieira FG.

Bioinformatics. 2019 Mar 23. pii: btz200. doi: 10.1093/bioinformatics/btz200. [Epub ahead of print]


Nocardiopsistins A-C: New angucyclines with anti-MRSA activity isolated from a marine sponge-derived Nocardiopsis sp. HB-J378.

Xu D, Nepal KK, Chen J, Harmody D, Zhu H, McCarthy PJ, Wright AE, Wang G.

Synth Syst Biotechnol. 2018 Nov 2;3(4):246-251. doi: 10.1016/j.synbio.2018.10.008. eCollection 2018 Dec.


Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture.

Wright AE, Fumagalli M, Cooney CR, Bloch NI, Vieira FG, Buechel SD, Kolm N, Mank JE.

Evol Lett. 2018 Feb 10;2(2):52-61. doi: 10.1002/evl3.39. eCollection 2018 Apr.


Microcystic Adnexal Carcinoma of the Nipple.

Wong LK, Kereke AR, Wright AE, Vyas KS.

Wounds. 2018 Jun;30(6):E65-E67.


The marine natural product Scalarin inhibits the receptor for advanced glycation end products (RAGE) and autophagy in the PANC-1 and MIA PaCa-2 pancreatic cancer cell lines.

Guzmán EA, Pitts TP, Diaz MC, Wright AE.

Invest New Drugs. 2019 Apr;37(2):262-270. doi: 10.1007/s10637-018-0635-4. Epub 2018 Jul 12.


Shared and Species-Specific Patterns of Nascent Y Chromosome Evolution in Two Guppy Species.

Morris J, Darolti I, Bloch NI, Wright AE, Mank JE.

Genes (Basel). 2018 May 3;9(5). pii: E238. doi: 10.3390/genes9050238.


Slow evolution of sex-biased genes in the reproductive tissue of the dioecious plant Salix viminalis.

Darolti I, Wright AE, Pucholt P, Berlin S, Mank JE.

Mol Ecol. 2018 Feb;27(3):694-708. doi: 10.1111/mec.14466. Epub 2018 Jan 22.


Prediction of need for intervention in posterior urethral valves: Use of urine osmolality.

Wright AE, Wragg R, Lopes J, Robb A, McCarthy L.

J Pediatr Surg. 2018 Feb;53(2):316-320. doi: 10.1016/j.jpedsurg.2017.11.026. Epub 2017 Nov 14.


Acute Ischemic Lesions Associated with Impairments in Expression and Recognition of Affective Prosody.

Wright AE, Davis C, Gomez Y, Posner J, Rorden C, Hillis AE, Tippett DC.

Perspect ASHA Spec Interest Groups. 2016 Jul;1(2):82-95. doi: 10.1044/persp1.SIG2.82. Epub 2016 Jul 12.


Selective Killing of Dormant Mycobacterium tuberculosis by Marine Natural Products.

Rodrigues Felix C, Gupta R, Geden S, Roberts J, Winder P, Pomponi SA, Diaz MC, Reed JK, Wright AE, Rohde KH.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00743-17. doi: 10.1128/AAC.00743-17. Print 2017 Aug.


Recent Sex Chromosome Divergence despite Ancient Dioecy in the Willow Salix viminalis.

Pucholt P, Wright AE, Conze LL, Mank JE, Berlin S.

Mol Biol Evol. 2017 Aug 1;34(8):1991-2001. doi: 10.1093/molbev/msx144.


Long-term follow-up of patients with multiple myeloma treated with total body irradiation-Melphalan conditioning.

Munker R, Baghian A, Koleva Y, Andrews P, Matharoo GS, Wright AE, Saba NS, Weiner RS, Safah H.

Eur J Haematol. 2017 Jul;99(1):56-59. doi: 10.1111/ejh.12890. Epub 2017 May 3.


Special Issue in Honor of Professor Phil Crews.

Cichewicz RH, Cragg GM, Linington RG, Wright AE.

J Nat Prod. 2017 Mar 24;80(3):579-581. doi: 10.1021/acs.jnatprod.7b00161. No abstract available.


Convergent recombination suppression suggests role of sexual selection in guppy sex chromosome formation.

Wright AE, Darolti I, Bloch NI, Oostra V, Sandkam B, Buechel SD, Kolm N, Breden F, Vicoso B, Mank JE.

Nat Commun. 2017 Jan 31;8:14251. doi: 10.1038/ncomms14251.


Analogues of the Potent Antitumor Compound Leiodermatolide from a Deep-Water Sponge of the Genus Leiodermatium.

Wright AE, Roberts JC, Guzmán EA, Pitts TP, Pomponi SA, Reed JK.

J Nat Prod. 2017 Mar 24;80(3):735-739. doi: 10.1021/acs.jnatprod.6b01140. Epub 2017 Jan 30.


Dragmacidin G, a Bioactive Bis-Indole Alkaloid from a Deep-Water Sponge of the Genus Spongosorites.

Wright AE, Killday KB, Chakrabarti D, Guzmán EA, Harmody D, McCarthy PJ, Pitts T, Pomponi SA, Reed JK, Roberts BF, Rodrigues Felix C, Rohde KH.

Mar Drugs. 2017 Jan 11;15(1). pii: E16. doi: 10.3390/md15010016.


Sperm competition shapes gene expression and sequence evolution in the ocellated wrasse.

Dean R, Wright AE, Marsh-Rollo SE, Nugent BM, Alonzo SH, Mank JE.

Mol Ecol. 2017 Jan;26(2):505-518. doi: 10.1111/mec.13919. Epub 2016 Dec 5.


Inhibition of IL-8 secretion on BxPC-3 and MIA PaCa-2 cells and induction of cytotoxicity in pancreatic cancer cells with marine natural products.

Guzmán EA, Harmody D, Pitts TP, Vera-Diaz B, Winder PL, Yu Y, Wright AE.

Anticancer Drugs. 2017 Feb;28(2):153-160. doi: 10.1097/CAD.0000000000000443.


Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.

Guzmán EA, Xu Q, Pitts TP, Mitsuhashi KO, Baker C, Linley PA, Oestreicher J, Tendyke K, Winder PL, Suh EM, Wright AE.

Int J Cancer. 2016 Nov 1;139(9):2116-26. doi: 10.1002/ijc.30253. Epub 2016 Jul 19.


How to make a sex chromosome.

Wright AE, Dean R, Zimmer F, Mank JE.

Nat Commun. 2016 Jul 4;7:12087. doi: 10.1038/ncomms12087. Review. No abstract available.


Development of effective prophylaxis against intraoperative carcinoid crisis.

Woltering EA, Wright AE, Stevens MA, Wang YZ, Boudreaux JP, Mamikunian G, Riopelle JM, Kaye AD.

J Clin Anesth. 2016 Aug;32:189-93. doi: 10.1016/j.jclinane.2016.03.008. Epub 2016 Apr 20.


Conservation of Regional Variation in Sex-Specific Sex Chromosome Regulation.

Wright AE, Zimmer F, Harrison PW, Mank JE.

Genetics. 2015 Oct;201(2):587-98. doi: 10.1534/genetics.115.179234. Epub 2015 Aug 5.


Evolution of dosage compensation under sexual selection differs between X and Z chromosomes.

Mullon C, Wright AE, Reuter M, Pomiankowski A, Mank JE.

Nat Commun. 2015 Jul 27;6:7720. doi: 10.1038/ncomms8720.


Positive Selection Underlies Faster-Z Evolution of Gene Expression in Birds.

Dean R, Harrison PW, Wright AE, Zimmer F, Mank JE.

Mol Biol Evol. 2015 Oct;32(10):2646-56. doi: 10.1093/molbev/msv138. Epub 2015 Jun 10.


What effect do different 200 μm laser fibres have on deflection and irrigation flow rates in a flexible ureterorenoscope?

Wright AE, Williams K, Rukin NJ.

Lasers Med Sci. 2015 Jul;30(5):1565-8. doi: 10.1007/s10103-015-1766-x. Epub 2015 May 14.


Sexual selection drives evolution and rapid turnover of male gene expression.

Harrison PW, Wright AE, Zimmer F, Dean R, Montgomery SH, Pointer MA, Mank JE.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4393-8. doi: 10.1073/pnas.1501339112. Epub 2015 Mar 23.


Variation in promiscuity and sexual selection drives avian rate of Faster-Z evolution.

Wright AE, Harrison PW, Zimmer F, Montgomery SH, Pointer MA, Mank JE.

Mol Ecol. 2015 Mar;24(6):1218-35. doi: 10.1111/mec.13113.


Transition from paediatric to adult health services in Scotland for young people with cerebral palsy.

Wright AE, Robb J, Shearer MC.

J Child Health Care. 2016 Jun;20(2):205-13. doi: 10.1177/1367493514564632. Epub 2015 Jan 15.


The marine natural product microsclerodermin A is a novel inhibitor of the nuclear factor kappa B and induces apoptosis in pancreatic cancer cells.

Guzmán EA, Maers K, Roberts J, Kemami-Wangun HV, Harmody D, Wright AE.

Invest New Drugs. 2015 Feb;33(1):86-94. doi: 10.1007/s10637-014-0185-3. Epub 2014 Nov 23.


Ureteroscopy and stones: Current status and future expectations.

Wright AE, Rukin NJ, Somani BK.

World J Nephrol. 2014 Nov 6;3(4):243-8. doi: 10.5527/wjn.v3.i4.243. Review.


Proposition for new terminologies in PCNL: what does 'ultra-mini-micro' actually mean?

Wright AE, Somani BK, Rukin NJ.

Urolithiasis. 2014 Dec;42(6):539-40. doi: 10.1007/s00240-014-0696-6. Epub 2014 Aug 2.


Independent stratum formation on the avian sex chromosomes reveals inter-chromosomal gene conversion and predominance of purifying selection on the W chromosome.

Wright AE, Harrison PW, Montgomery SH, Pointer MA, Mank JE.

Evolution. 2014 Nov;68(11):3281-95. doi: 10.1111/evo.12493. Epub 2014 Aug 29.


An unusual presentation of thoracoacromial artery pseudoaneurysm following shoulder arthroplasty.

Wright AE, Wall M, Slaney P, Downing R.

BMJ Case Rep. 2014 Jun 27;2014. pii: bcr2014204625. doi: 10.1136/bcr-2014-204625.


Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins.

Hassig CA, Zeng FY, Kung P, Kiankarimi M, Kim S, Diaz PW, Zhai D, Welsh K, Morshedian S, Su Y, O'Keefe B, Newman DJ, Rusman Y, Kaur H, Salomon CE, Brown SG, Baire B, Michel AR, Hoye TR, Francis S, Georg GI, Walters MA, Divlianska DB, Roth GP, Wright AE, Reed JC.

J Biomol Screen. 2014 Sep;19(8):1201-11. doi: 10.1177/1087057114536227. Epub 2014 May 27.


Effects of high-intensity interval exercise versus continuous moderate-intensity exercise on postprandial glycemic control assessed by continuous glucose monitoring in obese adults.

Little JP, Jung ME, Wright AE, Wright W, Manders RJ.

Appl Physiol Nutr Metab. 2014 Jul;39(7):835-41. doi: 10.1139/apnm-2013-0512. Epub 2014 Feb 18.


Indolo[3,2-a]carbazoles from a deep-water sponge of the genus Asteropus.

Russell F, Harmody D, McCarthy PJ, Pomponi SA, Wright AE.

J Nat Prod. 2013 Oct 25;76(10):1989-92. doi: 10.1021/np400501u. Epub 2013 Sep 24.


The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells.

Kallifatidis G, Hoepfner D, Jaeg T, Guzmán EA, Wright AE.

Mar Drugs. 2013 Sep 17;11(9):3500-16. doi: 10.3390/md11093500. Erratum in: Mar Drugs. 2014;12(4):2305-7.


Masculinization of gene expression is associated with exaggeration of male sexual dimorphism.

Pointer MA, Harrison PW, Wright AE, Mank JE.

PLoS Genet. 2013;9(8):e1003697. doi: 10.1371/journal.pgen.1003697. Epub 2013 Aug 15.


The scope and strength of sex-specific selection in genome evolution.

Wright AE, Mank JE.

J Evol Biol. 2013 Sep;26(9):1841-53. doi: 10.1111/jeb.12201. Epub 2013 Jul 13.


The bis(indolyl)imidazole alkaloid nortopsentin a exhibits antiplasmodial activity.

Alvarado S, Roberts BF, Wright AE, Chakrabarti D.

Antimicrob Agents Chemother. 2013 May;57(5):2362-4. doi: 10.1128/AAC.02091-12. Epub 2013 Feb 12.


Trade-off between selection for dosage compensation and masculinization on the avian Z chromosome.

Wright AE, Moghadam HK, Mank JE.

Genetics. 2012 Dec;192(4):1433-45. doi: 10.1534/genetics.112.145102. Epub 2012 Sep 20.


Altruism and the evolution of resource generalism and specialism.

Bonsall MB, Wright AE.

Ecol Evol. 2012 Mar;2(3):515-24. doi: 10.1002/ece3.206.


W chromosome expression responds to female-specific selection.

Moghadam HK, Pointer MA, Wright AE, Berlin S, Mank JE.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8207-11. doi: 10.1073/pnas.1202721109. Epub 2012 May 8.


Battle of the sexes: conflict over dosage-sensitive genes and the origin of X chromosome inactivation.

Wright AE, Mank JE.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5144-5. doi: 10.1073/pnas.1202905109. Epub 2012 Mar 21. No abstract available.


Natural products from the Lithistida: a review of the literature since 2000.

Winder PL, Pomponi SA, Wright AE.

Mar Drugs. 2011 Dec;9(12):2643-82. doi: 10.3390/md9122643. Epub 2011 Dec 15. Review.


The evolution of gene expression and the transcriptome-phenotype relationship.

Harrison PW, Wright AE, Mank JE.

Semin Cell Dev Biol. 2012 Apr;23(2):222-9. doi: 10.1016/j.semcdb.2011.12.004. Epub 2011 Dec 24. Review.

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