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Items: 1 to 50 of 166

1.

A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.

Seeherman HJ, Berasi SP, Brown CT, Martinez RX, Juo ZS, Jelinsky S, Cain MJ, Grode J, Tumelty KE, Bohner M, Grinberg O, Orr N, Shoseyov O, Eyckmans J, Chen C, Morales PR, Wilson CG, Vanderploeg EJ, Wozney JM.

Sci Transl Med. 2019 Apr 24;11(489). pii: eaar4953. doi: 10.1126/scitranslmed.aar4953.

PMID:
31019025
2.

New Insights into the Pathogenesis of MDS and the rational therapeutic opportunities.

Abou Zahr A, Bernabe Ramirez C, Wozney J, Prebet T, Zeidan AM.

Expert Rev Hematol. 2016;9(4):377-88. doi: 10.1586/17474086.2016.1135047. Epub 2016 Feb 15. Review.

PMID:
26734762
3.

Clarithromycin overcomes resistance to lenalidomide and dexamethasone in multiple myeloma.

Ghosh N, Tucker N, Zahurak M, Wozney J, Borrello I, Huff CA.

Am J Hematol. 2014 Aug;89(8):E116-20. doi: 10.1002/ajh.23733. Epub 2014 Apr 26.

4.

Growth factor and signaling pathways and their relevance to prostate cancer therapeutics.

Wozney JL, Antonarakis ES.

Cancer Metastasis Rev. 2014 Sep;33(2-3):581-94. doi: 10.1007/s10555-013-9475-z. Review.

5.

Successful treatment of severe refractory hepatic graft-versus-host disease by cadaveric liver transplant.

Zeidan AM, Wozney JL, Torbenson M, Krok K, Bolaños-Meade J.

Leuk Lymphoma. 2013 Dec;54(12):2756-9. doi: 10.3109/10428194.2013.788178. Epub 2013 Apr 30. Review. No abstract available.

6.

Intraosseous injection of rhBMP-2/calcium phosphate matrix improves bone structure and strength in the proximal aspect of the femur in chronic ovariectomized nonhuman primates.

Seeherman HJ, Li XJ, Smith E, Parkington J, Li R, Wozney JM.

J Bone Joint Surg Am. 2013 Jan 2;95(1):36-47. doi: 10.2106/JBJS.K.00668.

PMID:
23283371
7.

rhBMP-2/calcium phosphate matrix induces bone formation while limiting transient bone resorption in a nonhuman primate core defect model.

Seeherman HJ, Li XJ, Smith E, Wozney JM.

J Bone Joint Surg Am. 2012 Oct 3;94(19):1765-76. doi: 10.2106/JBJS.K.00523.

PMID:
23032587
8.

Evaluation of implants coated with recombinant human bone morphogenetic protein-2 and vacuum-dried using the critical-size supraalveolar peri-implant defect model in dogs.

Decker JF, Lee J, Cortella CA, Polimeni G, Rohrer MD, Wozney JM, Hall J, Susin C, Wikesjö UM.

J Periodontol. 2010 Dec;81(12):1839-49. doi: 10.1902/jop.2010.100220. Epub 2010 Jul 14.

PMID:
20629551
9.

Estimation of daily proteinuria in patients with multiple myeloma by using the protein-to-creatinine ratio in random urine samples.

Wozney JL, Damluji AA, Ahmed F, Zangari M, Loughran TP Jr, Talamo G.

Acta Haematol. 2010;123(4):226-9. doi: 10.1159/000313448. Epub 2010 Apr 27. No abstract available.

PMID:
20424436
10.

Evaluation of implants coated with rhBMP-2 using two different coating strategies: a critical-size supraalveolar peri-implant defect study in dogs.

Lee J, Decker JF, Polimeni G, Cortella CA, Rohrer MD, Wozney JM, Hall J, Susin C, Wikesjö UM.

J Clin Periodontol. 2010 Jun;37(6):582-90. doi: 10.1111/j.1600-051X.2010.01557.x. Epub 2010 Mar 23.

PMID:
20345393
11.

rhBMP-2 induces transient bone resorption followed by bone formation in a nonhuman primate core-defect model.

Seeherman HJ, Li XJ, Bouxsein ML, Wozney JM.

J Bone Joint Surg Am. 2010 Feb;92(2):411-26. doi: 10.2106/JBJS.H.01732.

PMID:
20124069
12.

Skin involvement in immunoglobulin E multiple myeloma.

Wozney JL, Ahmed F, Bayerl MG, Ehmann WC, Talamo G.

J Clin Oncol. 2009 Feb 1;27(4):637-8. doi: 10.1200/JCO.2008.20.1491. Epub 2008 Dec 8. No abstract available.

PMID:
19064952
13.

Alveolar ridge augmentation using implants coated with recombinant human bone morphogenetic protein-2: histologic observations.

Wikesjö UM, Qahash M, Polimeni G, Susin C, Shanaman RH, Rohrer MD, Wozney JM, Hall J.

J Clin Periodontol. 2008 Nov;35(11):1001-10. doi: 10.1111/j.1600-051X.2008.01321.x.

PMID:
18976397
14.

Bone formation at recombinant human bone morphogenetic protein-2-coated titanium implants in the posterior maxilla (Type IV bone) in non-human primates.

Wikesjö UM, Huang YH, Xiropaidis AV, Sorensen RG, Rohrer MD, Prasad HS, Wozney JM, Hall J.

J Clin Periodontol. 2008 Nov;35(11):992-1000. doi: 10.1111/j.1600-051X.2008.01322.x.

PMID:
18976396
15.

Bone formation at recombinant human bone morphogenetic protein-2-coated titanium implants in the posterior mandible (Type II bone) in dogs.

Wikesjö UM, Xiropaidis AV, Qahash M, Lim WH, Sorensen RG, Rohrer MD, Wozney JM, Hall J.

J Clin Periodontol. 2008 Nov;35(11):985-91. doi: 10.1111/j.1600-051X.2008.01318.x.

PMID:
18976395
16.

rhBMP-12 accelerates healing of rotator cuff repairs in a sheep model.

Seeherman HJ, Archambault JM, Rodeo SA, Turner AS, Zekas L, D'Augusta D, Li XJ, Smith E, Wozney JM.

J Bone Joint Surg Am. 2008 Oct;90(10):2206-19. doi: 10.2106/JBJS.G.00742.

PMID:
18829919
17.

A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy.

Wagner KR, Fleckenstein JL, Amato AA, Barohn RJ, Bushby K, Escolar DM, Flanigan KM, Pestronk A, Tawil R, Wolfe GI, Eagle M, Florence JM, King WM, Pandya S, Straub V, Juneau P, Meyers K, Csimma C, Araujo T, Allen R, Parsons SA, Wozney JM, Lavallie ER, Mendell JR.

Ann Neurol. 2008 May;63(5):561-71. doi: 10.1002/ana.21338.

PMID:
18335515
18.

Surface-etching enhances titanium implant osseointegration in newly formed (rhBMP-2-induced) and native bone.

Qahash M, Hardwick WR, Rohrer MD, Wozney JM, Wikesjö UM.

Int J Oral Maxillofac Implants. 2007 May-Jun;22(3):472-7.

PMID:
17622015
19.

Role of RGM coreceptors in bone morphogenetic protein signaling.

Halbrooks PJ, Ding R, Wozney JM, Bain G.

J Mol Signal. 2007 Jul 5;2:4.

20.

Bone formation at rhBMP-2-coated titanium implants in the rat ectopic model.

Hall J, Sorensen RG, Wozney JM, Wikesjö UM.

J Clin Periodontol. 2007 May;34(5):444-51.

PMID:
17448048
21.

Bone reconstruction following implantation of rhBMP-2 and guided bone regeneration in canine alveolar ridge defects.

Jovanovic SA, Hunt DR, Bernard GW, Spiekermann H, Wozney JM, Wikesjö UM.

Clin Oral Implants Res. 2007 Apr;18(2):224-30.

PMID:
17348887
22.

Regulation of TRP channel TRPM2 by the tyrosine phosphatase PTPL1.

Zhang W, Tong Q, Conrad K, Wozney J, Cheung JY, Miller BA.

Am J Physiol Cell Physiol. 2007 May;292(5):C1746-58. Epub 2007 Jan 24.

23.

rhBMP-2 delivered in a calcium phosphate cement accelerates bridging of critical-sized defects in rabbit radii.

Seeherman HJ, Azari K, Bidic S, Rogers L, Li XJ, Hollinger JO, Wozney JM.

J Bone Joint Surg Am. 2006 Jul;88(7):1553-65.

PMID:
16818982
24.

The effect of rhBMP-2 around endosseous implants with and without membranes in the canine model.

Jones AA, Buser D, Schenk R, Wozney J, Cochran DL.

J Periodontol. 2006 Jul;77(7):1184-93.

PMID:
16805681
25.

Engineering new bone with bone morphogenic proteins.

Wozney JM.

Ann Endocrinol (Paris). 2006 Apr;67(2):180-1. No abstract available.

PMID:
16639375
26.

rhBMP-2/calcium phosphate matrix accelerates osteotomy-site healing in a nonhuman primate model at multiple treatment times and concentrations.

Seeherman H, Li R, Bouxsein M, Kim H, Li XJ, Smith-Adaline EA, Aiolova M, Wozney JM.

J Bone Joint Surg Am. 2006 Jan;88(1):144-60.

PMID:
16391260
27.

Observations on healing following endodontic surgery in nonhuman primates (Macaca fascicularis): effects of rhBMP-2.

Bergenholtz G, Wikesjö UM, Sorensen RG, Xiropaidis AV, Wozney JM.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Jan;101(1):116-25. Epub 2005 Nov 2.

PMID:
16360616
28.

Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter.

Lee MH, Kim YJ, Yoon WJ, Kim JI, Kim BG, Hwang YS, Wozney JM, Chi XZ, Bae SC, Choi KY, Cho JY, Choi JY, Ryoo HM.

J Biol Chem. 2005 Oct 21;280(42):35579-87. Epub 2005 Aug 22.

29.

Evaluation of recombinant human bone morphogenetic protein-2 on the repair of alveolar ridge defects in baboons.

Miranda DA, Blumenthal NM, Sorensen RG, Wozney JM, Wikesjö UM.

J Periodontol. 2005 Feb;76(2):210-20.

PMID:
15974844
30.

Delivery of bone morphogenetic proteins for orthopedic tissue regeneration.

Seeherman H, Wozney JM.

Cytokine Growth Factor Rev. 2005 Jun;16(3):329-45. Review.

PMID:
15936978
31.

Injectable rhBMP-2/CPM paste for closed fracture and minimally invasive orthopaedic repairs.

Seeherman H, Li R, Li XJ, Wozney J.

J Musculoskelet Neuronal Interact. 2003 Dec;3(4):317-9; discussion 320-1. No abstract available.

32.

Identification of an N-terminal TRPC2 splice variant which inhibits calcium influx.

Chu X, Tong Q, Wozney J, Zhang W, Cheung JY, Conrad K, Mazack V, Stahl R, Barber DL, Miller BA.

Cell Calcium. 2005 Feb;37(2):173-82.

PMID:
15589997
33.

Protein-based tissue engineering in bone and cartilage repair.

Wozney JM, Seeherman HJ.

Curr Opin Biotechnol. 2004 Oct;15(5):392-8. Review.

PMID:
15464367
34.

Bone morphogenetic protein-2-induced alkaline phosphatase expression is stimulated by Dlx5 and repressed by Msx2.

Kim YJ, Lee MH, Wozney JM, Cho JY, Ryoo HM.

J Biol Chem. 2004 Dec 3;279(49):50773-80. Epub 2004 Sep 21.

35.

Recombinant human bone morphogenetic protein-2 delivered in an injectable calcium phosphate paste accelerates osteotomy-site healing in a nonhuman primate model.

Seeherman HJ, Bouxsein M, Kim H, Li R, Li XJ, Aiolova M, Wozney JM.

J Bone Joint Surg Am. 2004 Sep;86(9):1961-72.

PMID:
15342759
36.

Periodontal repair in dogs: evaluation of a bioresorbable calcium phosphate cement (Ceredex) as a carrier for rhBMP-2.

Sorensen RG, Wikesjö UM, Kinoshita A, Wozney JM.

J Clin Periodontol. 2004 Sep;31(9):796-804.

PMID:
15312104
37.

Periodontal repair in dogs: effect of recombinant human bone morphogenetic protein-12 (rhBMP-12) on regeneration of alveolar bone and periodontal attachment.

Wikesjö UM, Sorensen RG, Kinoshita A, Jian Li X, Wozney JM.

J Clin Periodontol. 2004 Aug;31(8):662-70. Review.

PMID:
15257745
38.

Effect of recombinant human bone morphogenetic protein-12 (rhBMP-12) on regeneration of periodontal attachment following tooth replantation in dogs.

Sorensen RG, Polimeni G, Kinoshita A, Wozney JM, Wikesjö UM.

J Clin Periodontol. 2004 Aug;31(8):654-61.

PMID:
15257744
39.

Long-term functional loading of dental implants in rhBMP-2 induced bone. A histologic study in the canine ridge augmentation model.

Jovanovic SA, Hunt DR, Bernard GW, Spiekermann H, Nishimura R, Wozney JM, Wikesjö UM.

Clin Oral Implants Res. 2003 Dec;14(6):793-803.

PMID:
15015957
40.

rhBMP-2 significantly enhances guided bone regeneration.

Wikesjö UM, Qahash M, Thomson RC, Cook AD, Rohrer MD, Wozney JM, Hardwick WR.

Clin Oral Implants Res. 2004 Apr;15(2):194-204.

PMID:
15008931
41.

Characterization of a calcium phosphate-based matrix for rhBMP-2.

Kim HD, Wozney JM, Li RH.

Methods Mol Biol. 2004;238:49-64. No abstract available.

PMID:
14970438
42.

Interaction of TRPC2 and TRPC6 in erythropoietin modulation of calcium influx.

Chu X, Tong Q, Cheung JY, Wozney J, Conrad K, Mazack V, Zhang W, Stahl R, Barber DL, Miller BA.

J Biol Chem. 2004 Mar 12;279(11):10514-22. Epub 2003 Dec 29.

43.

Locally delivered rhBMP-2 enhances bone ingrowth and gap healing in a canine model.

Sumner DR, Turner TM, Urban RM, Turek T, Seeherman H, Wozney JM.

J Orthop Res. 2004 Jan;22(1):58-65.

44.

rhBMP-2 injected in a calcium phosphate paste (alpha-BSM) accelerates healing in the rabbit ulnar osteotomy model.

Li RH, Bouxsein ML, Blake CA, D'Augusta D, Kim H, Li XJ, Wozney JM, Seeherman HJ.

J Orthop Res. 2003 Nov;21(6):997-1004.

45.
46.

BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2.

Lee MH, Kwon TG, Park HS, Wozney JM, Ryoo HM.

Biochem Biophys Res Commun. 2003 Sep 26;309(3):689-94.

PMID:
12963046
47.

A single percutaneous injection of recombinant human bone morphogenetic protein-2 accelerates fracture repair.

Einhorn TA, Majeska RJ, Mohaideen A, Kagel EM, Bouxsein ML, Turek TJ, Wozney JM.

J Bone Joint Surg Am. 2003 Aug;85(8):1425-35.

PMID:
12925621
48.

A review of preclinical program development for evaluating injectable carriers for osteogenic factors.

Seeherman H, Li R, Wozney J.

J Bone Joint Surg Am. 2003;85-A Suppl 3:96-108. Review. No abstract available.

PMID:
12925616
49.

Effect of recombinant human bone morphogenetic protein-2 in dehiscence defects with non-submerged immediate implants: an experimental study in Cynomolgus monkeys.

Hanisch O, Sorensen RG, Kinoshita A, Spiekermann H, Wozney JM, Wikesjö UM.

J Periodontol. 2003 May;74(5):648-57.

PMID:
12816297
50.

Periodontal repair in dogs: evaluation of a bioabsorbable space-providing macroporous membrane with recombinant human bone morphogenetic protein-2.

Wikesjö UM, Lim WH, Thomson RC, Cook AD, Wozney JM, Hardwick WR.

J Periodontol. 2003 May;74(5):635-47.

PMID:
12816296

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