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Items: 1 to 50 of 79

1.

Mitochondrial acetyl-CoA reversibly regulates locus-specific histone acetylation and gene expression.

Lozoya OA, Wang T, Grenet D, Wolfgang TC, Sobhany M, Ganini da Silva D, Riadi G, Chandel N, Woychik RP, Santos JH.

Life Sci Alliance. 2019 Feb 8;2(1). pii: e201800228. doi: 10.26508/lsa.201800228. Print 2019 Feb.

2.
3.

Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation.

Lozoya OA, Martinez-Reyes I, Wang T, Grenet D, Bushel P, Li J, Chandel N, Woychik RP, Santos JH.

PLoS Biol. 2018 Apr 18;16(4):e2005707. doi: 10.1371/journal.pbio.2005707. eCollection 2018 Apr.

4.

A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq.

Wang T, Santos JH, Feng J, Fargo DC, Shen L, Riadi G, Keeley E, Rosh ZS, Nestler EJ, Woychik RP.

PLoS One. 2016 Jul 14;11(7):e0159028. doi: 10.1371/journal.pone.0159028. eCollection 2016.

5.

Assessing human germ-cell mutagenesis in the Postgenome Era: a celebration of the legacy of William Lawson (Bill) Russell.

Wyrobek AJ, Mulvihill JJ, Wassom JS, Malling HV, Shelby MD, Lewis SE, Witt KL, Preston RJ, Perreault SD, Allen JW, Demarini DM, Woychik RP, Bishop JB.

Environ Mol Mutagen. 2007 Mar;48(2):71-95.

6.

The knockout mouse project.

Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B.

Nat Genet. 2004 Sep;36(9):921-4.

7.

Liver-specific expression of the agouti gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetes.

Kuklin AI, Mynatt RL, Klebig ML, Kiefer LL, Wilkison WO, Woychik RP, Michaud EJ.

Mol Cancer. 2004 Jun 2;3:17.

8.

Loss of the Tg737 protein results in skeletal patterning defects.

Zhang Q, Murcia NS, Chittenden LR, Richards WG, Michaud EJ, Woychik RP, Yoder BK.

Dev Dyn. 2003 May;227(1):78-90.

9.

Molecular and phenotypic analysis of 25 recessive, homozygous-viable alleles at the mouse agouti locus.

Miltenberger RJ, Wakamatsu K, Ito S, Woychik RP, Russell LB, Michaud EJ.

Genetics. 2002 Feb;160(2):659-74.

10.

Phenotypic variations of orpk mutation and chromosomal localization of modifiers influencing kidney phenotype.

Sommardahl C, Cottrell M, Wilkinson JE, Woychik RP, Johnson DK.

Physiol Genomics. 2001 Dec 21;7(2):127-34.

PMID:
11773599
11.

Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F.

Alagramam KN, Yuan H, Kuehn MH, Murcia CL, Wayne S, Srisailpathy CR, Lowry RB, Knaus R, Van Laer L, Bernier FP, Schwartz S, Lee C, Morton CC, Mullins RF, Ramesh A, Van Camp G, Hageman GS, Woychik RP, Smith RJ.

Hum Mol Genet. 2001 Aug 1;10(16):1709-18. Erratum in: Hum Mol Genet 2001 Oct 15;10(22):2603. Hagemen GS [corrected to Hageman GS].

PMID:
11487575
12.
13.

The mouse Ames waltzer hearing-loss mutant is caused by mutation of Pcdh15, a novel protocadherin gene.

Alagramam KN, Murcia CL, Kwon HY, Pawlowski KS, Wright CG, Woychik RP.

Nat Genet. 2001 Jan;27(1):99-102.

PMID:
11138007
14.

Persistent hyperplastic tunica vasculosa lentis and persistent hyperplastic primary vitreous in transgenic line TgN3261Rpw.

Colitz CM, Malarkey DE, Woychik RP, Wilkinson JE.

Vet Pathol. 2000 Sep;37(5):422-7.

PMID:
11055865
15.

Neuroepithelial defects of the inner ear in a new allele of the mouse mutation Ames waltzer.

Alagramam KN, Zahorsky-Reeves J, Wright CG, Pawlowski KS, Erway LC, Stubbs L, Woychik RP.

Hear Res. 2000 Oct;148(1-2):181-91.

PMID:
10978835
16.

The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination.

Murcia NS, Richards WG, Yoder BK, Mucenski ML, Dunlap JR, Woychik RP.

Development. 2000 Jun;127(11):2347-55.

17.

Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells.

Chen Y, Yee D, Dains K, Chatterjee A, Cavalcoli J, Schneider E, Om J, Woychik RP, Magnuson T.

Nat Genet. 2000 Mar;24(3):314-7.

PMID:
10700191
18.

Cellular pathophysiology of cystic kidney disease: insight into future therapies.

Avner ED, Woychik RP, Dell KM, Sweeney WE.

Int J Dev Biol. 1999;43(5):457-61. Review.

19.

Alternative processing of the human and mouse raly genes(1).

Khrebtukova I, Kuklin A, Woychik RP, Michaud EJ.

Biochim Biophys Acta. 1999 Oct 6;1447(1):107-12.

PMID:
10500250
20.

A new mouse insertional mutation that causes sensorineural deafness and vestibular defects.

Alagramam KN, Kwon HY, Cacheiro NL, Stubbs L, Wright CG, Erway LC, Woychik RP.

Genetics. 1999 Aug;152(4):1691-9.

21.

An agouti mutation lacking the basic domain induces yellow pigmentation but not obesity in transgenic mice.

Miltenberger RJ, Mynatt RL, Bruce BD, Wilkison WO, Woychik RP, Michaud EJ.

Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8579-84.

22.

Effective chemical mutagenesis in FVB/N mice requires low doses of ethylnitrosourea.

Davis AP, Woychik RP, Justice MJ.

Mamm Genome. 1999 Mar;10(3):308-10. No abstract available.

PMID:
10051330
23.

Corrigendum to: 'Utilization of microhomologous recombination in yeast to generate targeting constructs for mammalian genes'

Khrebtukova I I, Michaud EJ, Foster CM, Stark KL, Garfinkel DJ, Woychik RP.

Mutat Res. 1999 Jan 25;423(1-2):191. No abstract available.

PMID:
10029697
24.

The molecular biology of polycystic kidney disease.

Murcia NS, Woychik RP, Avner ED.

Pediatr Nephrol. 1998 Nov;12(9):721-6. Review.

PMID:
9874315
25.
26.

Functional genomics in the post-genome era.

Woychik RP, Klebig ML, Justice MJ, Magnuson TR, Avner ED.

Mutat Res. 1998 May 25;400(1-2):3-14. Review. Erratum in: Mutat Res 1998 Dec 3;422(2):367. Avrer ED [corrected to Avner ED].

PMID:
9685569
27.

Utilization of microhomologous recombination in yeast to generate targeting constructs for mammalian genes.

Khrebtukova I, Michaud EJ, Foster CM, Stark KL, Garfinkel DJ, Woychik RP.

Mutat Res. 1998 Jun 5;401(1-2):11-25. Erratum in: Mutat Res 1999 Jan 25;423(1-2):191.

PMID:
9639665
28.

Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease.

Richards WG, Sweeney WE, Yoder BK, Wilkinson JE, Woychik RP, Avner ED.

J Clin Invest. 1998 Mar 1;101(5):935-9.

29.
30.

Characterization of growth factor responsiveness and alterations in growth factor homeostasis involved in the tumorigenic conversion of mouse oval cells.

Isfort RJ, Cody DB, Richards WG, Yoder BK, Wilkinson JE, Woychik RP.

Growth Factors. 1998;15(2):81-94.

PMID:
9505165
31.

The combination of epidermal growth factor and transforming growth factor-beta induces novel phenotypic changes in mouse liver stem cell lines.

Isfort RJ, Cody DB, Stuard SB, Randall CJ, Miller C, Ridder GM, Doersen CJ, Richards WG, Yoder BK, Wilkinson JE, Woychik RP.

J Cell Sci. 1997 Dec;110 ( Pt 24):3117-29.

32.

Efficacy of taxol in the orpk mouse model of polycystic kidney disease.

Sommardahl CS, Woychik RP, Sweeney WE, Avner ED, Wilkinson JE.

Pediatr Nephrol. 1997 Dec;11(6):728-33.

PMID:
9438653
33.

Role of the agouti gene in obesity.

Michaud EJ, Mynatt RL, Miltenberger RJ, Klebig ML, Wilkinson JE, Zemel MB, Wilkison WO, Woychik RP.

J Endocrinol. 1997 Nov;155(2):207-9. Review. No abstract available.

PMID:
9415049
34.

The tetratricopeptide repeat containing Tg737 gene is a liver neoplasia tumor suppressor gene.

Isfort RJ, Cody DB, Doersen CJ, Richards WG, Yoder BK, Wilkinson JE, Kier LD, Jirtle RL, Isenberg JS, Klounig JE, Woychik RP.

Oncogene. 1997 Oct 9;15(15):1797-803.

35.

The role of the agouti gene in the yellow obese syndrome.

Miltenberger RJ, Mynatt RL, Wilkinson JE, Woychik RP.

J Nutr. 1997 Sep;127(9):1902S-1907S. Review.

PMID:
9278579
36.

Differential rescue of the renal and hepatic disease in an autosomal recessive polycystic kidney disease mouse mutant. A new model to study the liver lesion.

Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP.

Am J Pathol. 1997 Jun;150(6):2231-41.

37.

Isolation and characterization of liver epithelial cell lines from wild-type and mutant TgN737Rpw mice.

Richards WG, Yoder BK, Isfort RJ, Detilleux PG, Foster C, Neilsen N, Woychik RP, Wilkinson JE.

Am J Pathol. 1997 Apr;150(4):1189-97.

38.

Agouti regulation of intracellular calcium: role of melanocortin receptors.

Kim JH, Kiefer LL, Woychik RP, Wilkison WO, Truesdale A, Ittoop O, Willard D, Nichols J, Zemel MB.

Am J Physiol. 1997 Mar;272(3 Pt 1):E379-84.

PMID:
9124542
39.

Combined effects of insulin treatment and adipose tissue-specific agouti expression on the development of obesity.

Mynatt RL, Miltenberger RJ, Klebig ML, Zemel MB, Wilkinson JE, Wilkinson WO, Woychik RP.

Proc Natl Acad Sci U S A. 1997 Feb 4;94(3):919-22.

40.

The effects of calcium channel blockade on agouti-induced obesity.

Kim JH, Mynatt RL, Moore JW, Woychik RP, Moustaid N, Zemel MB.

FASEB J. 1996 Dec;10(14):1646-52.

PMID:
9002558
41.

Oval cell proliferation associated with the murine insertional mutation TgN737Rpw.

Richards WG, Yoder BK, Isfort RJ, Detilleux PG, Foster C, Neilsen N, Woychik RP, Wilkinson JE.

Am J Pathol. 1996 Dec;149(6):1919-30.

42.

Functional correction of renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA.

Yoder BK, Richards WG, Sommardahl C, Sweeney WE, Michaud EJ, Wilkinson JE, Avner ED, Woychik RP.

Kidney Int. 1996 Oct;50(4):1240-8.

43.

Upregulation of adipocyte metabolism by agouti protein: possible paracrine actions in yellow mouse obesity.

Jones BH, Kim JH, Zemel MB, Woychik RP, Michaud EJ, Wilkison WO, Moustaid N.

Am J Physiol. 1996 Jan;270(1 Pt 1):E192-6.

PMID:
8772492
44.

Sequence analysis of the human hTg737 gene and its polymorphic sites in patients with autosomal recessive polycystic kidney disease.

Onuchic LF, Schrick JJ, Ma J, Hudson T, Guay-Woodford LM, Zerres K, Woychik RP, Reeders ST.

Mamm Genome. 1995 Nov;6(11):805-8.

PMID:
8597639
45.

Deficiency of the beta 3 subunit of the type A gamma-aminobutyric acid receptor causes cleft palate in mice.

Culiat CT, Stubbs LJ, Woychik RP, Russell LB, Johnson DK, Rinchik EM.

Nat Genet. 1995 Nov;11(3):344-6.

PMID:
7581464
46.

Insertional mutagenesis and molecular analysis of a new gene associated with polycystic kidney disease.

Yoder BK, Richards WG, Sweeney WE, Wilkinson JE, Avener ED, Woychik RP.

Proc Assoc Am Physicians. 1995 Oct;107(3):314-23.

PMID:
8608416
47.

Analysis of polymerase chain reaction-amplified DNA products by mass spectrometry using matrix-assisted laser desorption and electrospray: current status.

Doktycz MJ, Hurst GB, Habibi-Goudarzi S, McLuckey SA, Tang K, Chen CH, Uziel M, Jacobson KB, Woychik RP, Buchanan MV.

Anal Biochem. 1995 Sep 20;230(2):205-14.

PMID:
7503409
48.
49.

Agouti regulation of intracellular calcium: role in the insulin resistance of viable yellow mice.

Zemel MB, Kim JH, Woychik RP, Michaud EJ, Kadwell SH, Patel IR, Wilkison WO.

Proc Natl Acad Sci U S A. 1995 May 23;92(11):4733-7.

50.

Ectopic expression of the agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur.

Klebig ML, Wilkinson JE, Geisler JG, Woychik RP.

Proc Natl Acad Sci U S A. 1995 May 23;92(11):4728-32.

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