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Items: 1 to 50 of 701

1.

Fatigue is highly prevalent in patients with COPD and correlates poorly with the degree of airflow limitation.

Goërtz YMJ, Spruit MA, Van 't Hul AJ, Peters JB, Van Herck M, Nakken N, Djamin RS, Burtin C, Thong MSY, Coors A, Meertens-Kerris Y, Wouters EFM, Prins JB, Franssen FME, Muris JWM, Vanfleteren LEGW, Sprangers MAG, Janssen DJA, Vercoulen JH.

Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619878128. doi: 10.1177/1753466619878128.

2.

Effects of a comprehensive, inpatient pulmonary rehabilitation programme in a cachectic patient with very severe COPD and chronic respiratory failure.

Franssen FME, Vanfleteren LEGW, Janssen DJA, Wouters EFM, Spruit MA.

Breathe (Sheff). 2019 Sep;15(3):227-233. doi: 10.1183/20734735.0186-2019.

3.

Cell Type- and Exposure-Specific Modulation of CD63/CD81-Positive and Tissue Factor-Positive Extracellular Vesicle Release in response to Respiratory Toxicants.

Stassen FRM, van Eijck PH, Savelkoul PHM, Wouters EFM, Rohde GGU, Briedé JJ, Reynaert NL, de Kok TM, Benedikter BJ.

Oxid Med Cell Longev. 2019 Aug 14;2019:5204218. doi: 10.1155/2019/5204218. eCollection 2019.

4.

Personalized medicine for patients with COPD: where are we?

Franssen FM, Alter P, Bar N, Benedikter BJ, Iurato S, Maier D, Maxheim M, Roessler FK, Spruit MA, Vogelmeier CF, Wouters EF, Schmeck B.

Int J Chron Obstruct Pulmon Dis. 2019 Jul 9;14:1465-1484. doi: 10.2147/COPD.S175706. eCollection 2019.

5.

Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease.

Piscaer I, van den Ouweland JMW, Vermeersch K, Reynaert NL, Franssen FME, Keene S, Wouters EFM, Janssens W, Vermeer C, Janssen R.

J Clin Med. 2019 Jul 27;8(8). pii: E1116. doi: 10.3390/jcm8081116.

6.

Clustering of 27,525,663 Death Records from the United States Based on Health Conditions Associated with Death: An Example of big Health Data Exploration.

Janssen DJA, Rechberger S, Wouters EFM, Schols JMGA, Johnson MJ, Currow DC, Curtis JR, Spruit MA.

J Clin Med. 2019 Jun 27;8(7). pii: E922. doi: 10.3390/jcm8070922.

7.

Wearable Finger Pulse Oximetry for Continuous Oxygen Saturation Measurements During Daily Home Routines of Patients With Chronic Obstructive Pulmonary Disease (COPD) Over One Week: Observational Study.

Buekers J, Theunis J, De Boever P, Vaes AW, Koopman M, Janssen EV, Wouters EF, Spruit MA, Aerts JM.

JMIR Mhealth Uhealth. 2019 Jun 6;7(6):e12866. doi: 10.2196/12866.

8.

The superexacerbator phenotype in patients with COPD: a descriptive analysis.

Vanfleteren LEGW, Boonen LMC, Spruit MA, Janssen DJA, Wouters EFM, Franssen FME.

ERJ Open Res. 2019 Jun 4;5(2). pii: 00235-2018. doi: 10.1183/23120541.00235-2018. eCollection 2019 Apr.

9.

Vertebral bone attenuation in Hounsfield Units and prevalent vertebral fractures are associated with the short-term risk of vertebral fractures in current and ex-smokers with and without COPD: a 3-year chest CT follow-up study.

van Dort MJ, Driessen JHM, Geusens P, Romme EAPM, Smeenk FWJM, Wouters EFM, van den Bergh JPW.

Osteoporos Int. 2019 Aug;30(8):1561-1571. doi: 10.1007/s00198-019-04977-w. Epub 2019 Jun 3.

10.

Airflow Obstruction and Cardio-metabolic Comorbidities.

Triest FJJ, Studnicka M, Franssen FME, Vollmer WM, Lamprecht B, Wouters EFM, Burney PGJ, Vanfleteren LEGW.

COPD. 2019 Apr;16(2):109-117. doi: 10.1080/15412555.2019.1614550. Epub 2019 May 27.

PMID:
31131642
11.

It's more than low BMI: prevalence of cachexia and associated mortality in COPD.

McDonald MN, Wouters EFM, Rutten E, Casaburi R, Rennard SI, Lomas DA, Bamman M, Celli B, Agusti A, Tal-Singer R, Hersh CP, Dransfield M, Silverman EK.

Respir Res. 2019 May 22;20(1):100. doi: 10.1186/s12931-019-1073-3.

12.

Blood Eosinophil Counts, Withdrawal of Inhaled Corticosteroids and Risk of COPD Exacerbations and Mortality in the Clinical Practice Research Datalink (CPRD).

Oshagbemi OA, Franssen FME, van Kraaij S, Braeken DCW, Wouters EFM, Maitland-van der Zee AH, Driessen JHM, de Vries F.

COPD. 2019 Apr;16(2):152-159. doi: 10.1080/15412555.2019.1608172. Epub 2019 May 23.

PMID:
31117850
13.

Disease-Specific Comorbidity Clusters in COPD and Accelerated Aging.

Triest FJJ, Franssen FME, Reynaert N, Gaffron S, Spruit MA, Janssen DJA, Rutten EPA, Wouters EFM, Vanfleteren LEGW.

J Clin Med. 2019 Apr 14;8(4). pii: E511. doi: 10.3390/jcm8040511.

14.

The Medusa faces of dyspnoea in COPD.

Wouters EFM.

Eur Respir J. 2019 Apr 18;53(4). pii: 1900487. doi: 10.1183/13993003.00487-2019. Print 2019 Apr. No abstract available.

PMID:
31000669
15.

Revealing Methodological Challenges in Chronic Obstructive Pulmonary Disease Studies Assessing Comorbidities: A Narrative Review.

Houben-Wilke S, Triest FJJ, Franssen FME, Janssen DJA, Wouters EFM, Vanfleteren LEGW.

Chronic Obstr Pulm Dis. 2019 Apr 9;6(2):166-177. doi: 10.15326/jcopdf.6.2.2018.0145. Epub 2019 Apr 9. Review.

16.

Exhaled Volatile Organic Compounds Are Able to Discriminate between Neutrophilic and Eosinophilic Asthma.

Schleich FN, Zanella D, Stefanuto PH, Bessonov K, Smolinska A, Dallinga JW, Henket M, Paulus V, Guissard F, Graff S, Moermans C, Wouters EFM, Van Steen K, van Schooten FJ, Focant JF, Louis R.

Am J Respir Crit Care Med. 2019 Aug 15;200(4):444-453. doi: 10.1164/rccm.201811-2210OC.

PMID:
30973757
17.

Effects of Pulmonary Rehabilitation on Gait Characteristics in Patients with COPD.

Liu WY, Meijer K, Delbressine JM, Willems PJ, Wouters EF, Spruit MA.

J Clin Med. 2019 Apr 5;8(4). pii: E459. doi: 10.3390/jcm8040459.

18.

Clinical outcome and cost-effectiveness of a 1-year nutritional intervention programme in COPD patients with low muscle mass: The randomized controlled NUTRAIN trial.

van Beers M, Rutten-van Mölken MPMH, van de Bool C, Boland M, Kremers SPJ, Franssen FME, van Helvoort A, Gosker HR, Wouters EF, Schols AMWJ.

Clin Nutr. 2019 Mar 18. pii: S0261-5614(19)30114-1. doi: 10.1016/j.clnu.2019.03.001. [Epub ahead of print]

19.

Risk stratification for short-term mortality at hospital admission for acute exacerbations of COPD.

Sprooten RTM, Rohde GGU, Lawyer G, Leijte WT, Wouters EFM, Franssen FME.

Respirology. 2019 Aug;24(8):765-776. doi: 10.1111/resp.13538. Epub 2019 Mar 21.

PMID:
30897284
20.

Pulmonary rehabilitation, physical activity, respiratory failure and palliative respiratory care.

Spruit MA, Rochester CL, Pitta F, Kenn K, Schols AMWJ, Hart N, Wouters EFM, Nava S, Dreher M, Janssen DJA, Johnson MJ, Curtis RJ, Sastry M, Franssen FME.

Thorax. 2019 Jul;74(7):693-699. doi: 10.1136/thoraxjnl-2018-212044. Epub 2019 Mar 14.

PMID:
30872364
21.

Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles.

Benedikter BJ, Bouwman FG, Heinzmann ACA, Vajen T, Mariman EC, Wouters EFM, Savelkoul PHM, Koenen RR, Rohde GGU, van Oerle R, Spronk HM, Stassen FRM.

J Extracell Vesicles. 2019 Mar 5;8(1):1585163. doi: 10.1080/20013078.2019.1585163. eCollection 2019.

22.

Organizational aspects of pulmonary rehabilitation in chronic respiratory diseases.

Spruit MA, Wouters EFM.

Respirology. 2019 Sep;24(9):838-843. doi: 10.1111/resp.13512. Epub 2019 Feb 27. Review.

23.

Emphysema: looking beyond alpha-1 antitrypsin deficiency.

Janssen R, Piscaer I, Franssen FME, Wouters EFM.

Expert Rev Respir Med. 2019 Apr;13(4):381-397. doi: 10.1080/17476348.2019.1580575. Epub 2019 Feb 22.

PMID:
30761929
24.

Thoracic Kyphosis on Chest CT Scans Is Associated With Incident Vertebral Fractures in Smokers.

van Dort MJ, Driessen JH, Romme EA, Geusens P, Willems PC, Smeenk FW, Wouters EF, van den Bergh JP.

J Bone Miner Res. 2019 May;34(5):859-866. doi: 10.1002/jbmr.3672. Epub 2019 Feb 27.

PMID:
30690782
25.

Cluster-randomised trial of a nurse-led advance care planning session in patients with COPD and their loved ones.

Houben CHM, Spruit MA, Luyten H, Pennings HJ, van den Boogaart VEM, Creemers JPHM, Wesseling G, Wouters EFM, Janssen DJA.

Thorax. 2019 Apr;74(4):328-336. doi: 10.1136/thoraxjnl-2018-211943. Epub 2019 Jan 19.

PMID:
30661022
26.

Comprehensive Lung Function Assessment Does not Allow to Infer Response to Pulmonary Rehabilitation in Patients with COPD.

Augustin IML, Wouters EFM, Houben-Wilke S, Gaffron S, Janssen DJA, Franssen FME, Spruit MA.

J Clin Med. 2018 Dec 27;8(1). pii: E27. doi: 10.3390/jcm8010027.

27.

Spirometric changes during exacerbations of COPD: a post hoc analysis of the WISDOM trial.

Watz H, Tetzlaff K, Magnussen H, Mueller A, Rodriguez-Roisin R, Wouters EFM, Vogelmeier C, Calverley PMA.

Respir Res. 2018 Dec 13;19(1):251. doi: 10.1186/s12931-018-0944-3.

28.

Impact of pulmonary rehabilitation on activities of daily living in patients with chronic obstructive pulmonary disease.

Vaes AW, Delbressine JML, Mesquita R, Goertz YMJ, Janssen DJA, Nakken N, Franssen FME, Vanfleteren LEGW, Wouters EFM, Spruit MA.

J Appl Physiol (1985). 2019 Mar 1;126(3):607-615. doi: 10.1152/japplphysiol.00790.2018. Epub 2018 Nov 29.

PMID:
30496707
29.

Fatigue is Highly Prevalent in Patients with Asthma and Contributes to the Burden of Disease.

Van Herck M, Spruit MA, Burtin C, Djamin R, Antons J, Goërtz YMJ, Ebadi Z, Janssen DJA, Vercoulen JH, Peters JB, Thong MSY, Otker J, Coors A, Sprangers MAG, Muris JWM, Wouters EFM, van 't Hul AJ.

J Clin Med. 2018 Nov 23;7(12). pii: E471. doi: 10.3390/jcm7120471.

30.

Contribution of individual COPD assessment test (CAT) items to CAT total score and effects of pulmonary rehabilitation on CAT scores.

Houben-Wilke S, Janssen DJA, Franssen FME, Vanfleteren LEGW, Wouters EFM, Spruit MA.

Health Qual Life Outcomes. 2018 Oct 30;16(1):205. doi: 10.1186/s12955-018-1034-4.

31.

Trends in moderate and severe exacerbations among COPD patients in the UK from 2005 to 2013.

Oshagbemi OA, Keene SJ, Driessen JHM, Jordan R, Wouters EFM, de Boer A, de Vries F, Franssen FME.

Respir Med. 2018 Nov;144:1-6. doi: 10.1016/j.rmed.2018.09.010. Epub 2018 Sep 17.

PMID:
30366578
32.

Chronic Obstructive Pulmonary Disease: Shifting the Paradigm to the Vasculature.

Wouters EFM, Franssen FM.

Am J Respir Crit Care Med. 2019 Feb 1;199(3):258-259. doi: 10.1164/rccm.201808-1542ED. No abstract available.

PMID:
30265129
33.

Blood eosinophilia, use of inhaled corticosteroids, and risk of COPD exacerbations and mortality.

Oshagbemi OA, Franssen FME, Braeken DCW, Henskens Y, Wouters EFM, Maitland-van der Zee AH, Burden AM, de Vries F.

Pharmacoepidemiol Drug Saf. 2018 Nov;27(11):1191-1199. doi: 10.1002/pds.4655. Epub 2018 Sep 28.

34.

Copper as the most likely pathogenic divergence factor between lung fibrosis and emphysema.

Janssen R, de Brouwer B, von der Thüsen JH, Wouters EFM.

Med Hypotheses. 2018 Nov;120:49-54. doi: 10.1016/j.mehy.2018.08.003. Epub 2018 Aug 14.

PMID:
30220340
35.

The respiratory physiome: Clustering based on a comprehensive lung function assessment in patients with COPD.

Augustin IML, Spruit MA, Houben-Wilke S, Franssen FME, Vanfleteren LEGW, Gaffron S, Janssen DJA, Wouters EFM.

PLoS One. 2018 Sep 12;13(9):e0201593. doi: 10.1371/journal.pone.0201593. eCollection 2018.

36.

Supplementation with Qter® and Creatine improves functional performance in COPD patients on long term oxygen therapy.

De Benedetto F, Pastorelli R, Ferrario M, de Blasio F, Marinari S, Brunelli L, Wouters EFM, Polverino F, Celli BR; Interdisciplinary Association for Research in Lung Disease (AIMAR) Study Group.

Respir Med. 2018 Sep;142:86-93. doi: 10.1016/j.rmed.2018.08.002. Epub 2018 Aug 7.

PMID:
30170808
37.

Peripheral endothelial function is positively associated with maximal aerobic capacity in patients with chronic obstructive pulmonary disease.

Vaes AW, Spruit MA, Theunis J, Wouters EFM, De Boever P.

Respir Med. 2018 Sep;142:41-47. doi: 10.1016/j.rmed.2018.07.013. Epub 2018 Jul 21.

PMID:
30170800
38.

Identifying causes of perceptual differences in problematic activities of daily life between patients with COPD and proxies: A qualitative study.

Nakken N, Spruit MA, van den Bogaart EHA, Crutzen R, Muris JWM, Wouters EFM, Janssen DJA.

Aust Occup Ther J. 2019 Feb;66(1):44-51. doi: 10.1111/1440-1630.12512. Epub 2018 Aug 29.

PMID:
30156291
39.

The physical, mental, and social impact of COPD in a population-based sample: results from the Longitudinal Aging Study Amsterdam.

Franssen FME, Smid DE, Deeg DJH, Huisman M, Poppelaars J, Wouters EFM, Spruit MA.

NPJ Prim Care Respir Med. 2018 Aug 10;28(1):30. doi: 10.1038/s41533-018-0097-3.

40.

Whole exome sequencing analysis in severe chronic obstructive pulmonary disease.

Qiao D, Ameli A, Prokopenko D, Chen H, Kho AT, Parker MM, Morrow J, Hobbs BD, Liu Y, Beaty TH, Crapo JD, Barnes KC, Nickerson DA, Bamshad M, Hersh CP, Lomas DA, Agusti A, Make BJ, Calverley PMA, Donner CF, Wouters EF, Vestbo J, Paré PD, Levy RD, Rennard SI, Tal-Singer R, Spitz MR, Sharma A, Ruczinski I, Lange C, Silverman EK, Cho MH.

Hum Mol Genet. 2018 Nov 1;27(21):3801-3812. doi: 10.1093/hmg/ddy269.

PMID:
30060175
41.

Adverse respiratory effects of opioids for chronic breathlessness: to what extent can we learn lessons from chronic pain?

Verberkt CA, van den Beuken-van Everdingen MHJ, Schols JMGA, Datla S, Dirksen CD, Johnson MJ, van Kuijk SMJ, Wouters EFM, Janssen DJA.

Eur Respir J. 2018 Jul 19;52(1). pii: 1800882. doi: 10.1183/13993003.00882-2018. Print 2018 Jul. No abstract available.

PMID:
30026306
42.

Collagen Degradation and Formation Are Elevated in Exacerbated COPD Compared With Stable Disease.

Schumann DM, Leeming D, Papakonstantinou E, Blasi F, Kostikas K, Boersma W, Louis R, Milenkovic B, Aerts J, Sand JMB, Wouters EFM, Rohde G, Prat C, Torres A, Welte T, Tamm M, Karsdal M, Stolz D.

Chest. 2018 Oct;154(4):798-807. doi: 10.1016/j.chest.2018.06.028. Epub 2018 Jun 30.

43.

Effectiveness of Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease With Different Degrees of Static Lung Hyperinflation.

Vanfleteren MJ, Koopman M, Spruit MA, Pennings HJ, Smeenk F, Pieters W, van den Bergh JJ, Michels AJ, Wouters EF, Groenen MT, Franssen FM, Vanfleteren LE.

Arch Phys Med Rehabil. 2018 Nov;99(11):2279-2286.e3. doi: 10.1016/j.apmr.2018.05.011. Epub 2018 Jun 12.

PMID:
29906421
44.

COPD patient education and support - Achieving patient-centredness.

Stoilkova-Hartmann A, Franssen FME, Augustin IML, Wouters EFM, Barnard KD.

Patient Educ Couns. 2018 Nov;101(11):2031-2036. doi: 10.1016/j.pec.2018.05.024. Epub 2018 Jun 1.

PMID:
29884533
45.

COPD stands for complex obstructive pulmonary disease.

Houben-Wilke S, Augustin IM, Vercoulen JH, van Ranst D, Bij de Vaate E, Wempe JB, Spruit MA, Wouters EFM, Franssen FME.

Eur Respir Rev. 2018 Jun 6;27(148). pii: 180027. doi: 10.1183/16000617.0027-2018. Print 2018 Jun 30. Review.

46.

Looking into the eye of patients with chronic obstructive pulmonary disease: an opportunity for better microvascular profiling of these complex patients.

Vaes AW, Spruit MA, Theunis J, Goswami N, Vanfleteren LE, Franssen FME, Wouters EFM, De Boever P.

Acta Ophthalmol. 2018 Sep;96(6):539-549. doi: 10.1111/aos.13765. Epub 2018 May 16. Review.

47.

Determinants of functional, peak and endurance exercise capacity in people with chronic obstructive pulmonary disease.

McNamara RJ, Houben-Wilke S, Franssen FME, Smid DE, Vanfleteren LEGW, Groenen MTJ, Uszko-Lencer NHMK, Wouters EFM, Alison JA, Spruit MA.

Respir Med. 2018 May;138:81-87. doi: 10.1016/j.rmed.2018.03.032. Epub 2018 Mar 29.

PMID:
29724398
48.

Extracellular vesicles released in response to respiratory exposures: implications for chronic disease.

Benedikter BJ, Wouters EFM, Savelkoul PHM, Rohde GGU, Stassen FRM.

J Toxicol Environ Health B Crit Rev. 2018;21(3):142-160. doi: 10.1080/10937404.2018.1466380. Epub 2018 May 1.

PMID:
29714636
49.

Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells.

Perkins TN, Peeters PM, Albrecht C, Schins RPF, Dentener MA, Mossman BT, Wouters EFM, Reynaert NL.

Toxicol Appl Pharmacol. 2018 Jun 1;348:43-53. doi: 10.1016/j.taap.2018.04.011. Epub 2018 Apr 17.

PMID:
29673857
50.

Left ventricular volume and wall stress are linked to lung function impairment in COPD.

Alter P, Jörres RA, Watz H, Welte T, Gläser S, Schulz H, Bals R, Karch A, Wouters EFM, Vestbo J, Young D, Vogelmeier CF.

Int J Cardiol. 2018 Jun 15;261:172-178. doi: 10.1016/j.ijcard.2018.02.074.

PMID:
29657040

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