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Items: 1 to 50 of 87

1.

G protein-coupled receptor signaling in VTA dopaminergic neurons bidirectionally regulates the acute locomotor response to amphetamine but does not affect behavioral sensitization.

Runegaard AH, Dencker D, Wörtwein G, Gether U.

Neuropharmacology. 2019 Jun 4. pii: S0028-3908(19)30209-6. doi: 10.1016/j.neuropharm.2019.06.002. [Epub ahead of print]

PMID:
31173760
2.

Glucagon-Like Peptide-1 Receptor Agonist Treatment Does Not Reduce Abuse-Related Effects of Opioid Drugs.

Bornebusch AB, Fink-Jensen A, Wörtwein G, Seeley RJ, Thomsen M.

eNeuro. 2019 Apr 24;6(2). pii: ENEURO.0443-18.2019. doi: 10.1523/ENEURO.0443-18.2019. eCollection 2019 Mar-Apr.

3.

Markers of HPA-axis activity and nucleic acid damage from oxidation after electroconvulsive stimulations in rats.

Jorgensen A, Breitenstein K, Kalliokoski O, Weimann A, Henriksen T, Poulsen HE, Jorgensen MB, Wörtwein G.

Acta Neuropsychiatr. 2019 Mar 11:1-29. doi: 10.1017/neu.2019.7. [Epub ahead of print]

PMID:
30854991
4.

Increased oxidation of RNA despite reduced mitochondrial respiration after chronic electroconvulsive stimulation of rat brain tissue.

Nielsen B, Cejvanovic V, Wörtwein G, Hansen AR, Marstal KK, Weimann A, Bjerring PN, Dela F, Poulsen HE, Jørgensen MB.

Neurosci Lett. 2019 Jan 18;690:1-5. doi: 10.1016/j.neulet.2018.09.061. Epub 2018 Oct 1.

PMID:
30287304
5.

Initial rewarding effects of cocaine and amphetamine assessed in a day using the single-exposure place preference protocol.

Runegaard AH, Jensen KL, Wörtwein G, Gether U.

Eur J Neurosci. 2018 Jul 25. doi: 10.1111/ejn.14082. [Epub ahead of print]

PMID:
30044020
6.

Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons.

Runegaard AH, Sørensen AT, Fitzpatrick CM, Jørgensen SH, Petersen AV, Hansen NW, Weikop P, Andreasen JT, Mikkelsen JD, Perrier JF, Woldbye D, Rickhag M, Wortwein G, Gether U.

eNeuro. 2018 Jun 18;5(3). pii: ENEURO.0345-17.2018. doi: 10.1523/ENEURO.0345-17.2018. eCollection 2018 May-Jun.

7.

PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis.

Jensen KL, Sørensen G, Dencker D, Owens WA, Rahbek-Clemmensen T, Brett Lever M, Runegaard AH, Riis Christensen N, Weikop P, Wörtwein G, Fink-Jensen A, Madsen KL, Daws L, Gether U, Rickhag M.

eNeuro. 2018 Jun 11;5(3). pii: ENEURO.0422-17.2018. doi: 10.1523/ENEURO.0422-17.2018. eCollection 2018 May-Jun.

8.

Ketogenic Diet Suppresses Alcohol Withdrawal Syndrome in Rats.

Dencker D, Molander A, Thomsen M, Schlumberger C, Wortwein G, Weikop P, Benveniste H, Volkow ND, Fink-Jensen A.

Alcohol Clin Exp Res. 2018 Feb;42(2):270-277. doi: 10.1111/acer.13560. Epub 2017 Dec 23.

PMID:
29160944
9.

[Erythropoietin treatment may improve cognition in neuropsychiatric disorders].

Kjær KS, Hageman I, Wörtwein G, Jørgensen MB, Miskowiak KW.

Ugeskr Laeger. 2017 Aug 14;179(33). pii: V01170037. Review. Danish.

PMID:
28869012
10.

The glucagon-like peptide 1 receptor agonist Exendin-4 decreases relapse-like drinking in socially housed mice.

Thomsen M, Dencker D, Wörtwein G, Weikop P, Egecioglu E, Jerlhag E, Fink-Jensen A, Molander A.

Pharmacol Biochem Behav. 2017 Sep;160:14-20. doi: 10.1016/j.pbb.2017.07.014. Epub 2017 Aug 1.

PMID:
28778739
11.
12.

Subjective perception of cocaine reward in mice assessed by a single exposure place preference (sePP) paradigm.

Runegaard AH, Jensen KL, Dencker D, Wörtwein G, Gether U.

J Neurosci Methods. 2017 Sep 1;289:85-92. doi: 10.1016/j.jneumeth.2017.07.010. Epub 2017 Jul 12.

PMID:
28711378
13.

Muscarinic receptor M4 positive allosteric modulators attenuate central effects of cocaine.

Dall C, Weikop P, Dencker D, Molander AC, Wörtwein G, Conn PJ, Fink-Jensen A, Thomsen M.

Drug Alcohol Depend. 2017 Jul 1;176:154-161. doi: 10.1016/j.drugalcdep.2017.03.014. Epub 2017 May 16.

14.

A chronic increase of corticosterone age-dependently reduces systemic DNA damage from oxidation in rats.

Jorgensen A, Kalliokoski O, Forsberg K, Breitenstein K, Weimann A, Henriksen T, Hau J, Wörtwein G, Poulsen HE, Jorgensen MB.

Free Radic Biol Med. 2017 Mar;104:64-74. doi: 10.1016/j.freeradbiomed.2017.01.013. Epub 2017 Jan 7.

PMID:
28069523
15.

The Circadian Oscillator of the Cerebral Cortex: Molecular, Biochemical and Behavioral Effects of Deleting the Arntl Clock Gene in Cortical Neurons.

Bering T, Carstensen MB, Wörtwein G, Weikop P, Rath MF.

Cereb Cortex. 2018 Feb 1;28(2):644-657. doi: 10.1093/cercor/bhw406.

PMID:
28052921
16.

Electroconvulsive stimulation results in long-term survival of newly generated hippocampal neurons in rats.

Olesen MV, Wörtwein G, Folke J, Pakkenberg B.

Hippocampus. 2017 Jan;27(1):52-60. doi: 10.1002/hipo.22670. Epub 2016 Oct 31.

PMID:
27756104
17.

5-HT2A Receptor Binding in the Frontal Cortex of Parkinson's Disease Patients and Alpha-Synuclein Overexpressing Mice: A Postmortem Study.

Rasmussen NB, Olesen MV, Brudek T, Plenge P, Klein AB, Westin JE, Fog K, Wörtwein G, Aznar S.

Parkinsons Dis. 2016;2016:3682936. doi: 10.1155/2016/3682936. Epub 2016 Aug 4.

18.

Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels.

Reddy IA, Pino JA, Weikop P, Osses N, Sørensen G, Bering T, Valle C, Bluett RJ, Erreger K, Wortwein G, Reyes JG, Graham D, Stanwood GD, Hackett TA, Patel S, Fink-Jensen A, Torres GE, Galli A.

Transl Psychiatry. 2016 May 17;6:e809. doi: 10.1038/tp.2016.86.

19.

Delayed restraint procedure enhances cognitive recovery of spatial function after fimbria-fornix transection.

Gram MG, Wogensen E, Wörtwein G, Mogensen J, Malá H.

Restor Neurol Neurosci. 2015;34(1):1-17. doi: 10.3233/RNN-140396.

PMID:
26518669
20.

The glucagon-like peptide 1 (GLP-1) receptor agonist exendin-4 reduces cocaine self-administration in mice.

Sørensen G, Reddy IA, Weikop P, Graham DL, Stanwood GD, Wortwein G, Galli A, Fink-Jensen A.

Physiol Behav. 2015 Oct 1;149:262-8. doi: 10.1016/j.physbeh.2015.06.013. Epub 2015 Jun 11.

21.

Dynamic regulation of cerebral DNA repair genes by psychological stress.

Forsberg K, Aalling N, Wörtwein G, Loft S, Møller P, Hau J, Hageman I, Jørgensen MB, Jørgensen A.

Mutat Res Genet Toxicol Environ Mutagen. 2015 Jan 15;778:37-43. doi: 10.1016/j.mrgentox.2014.12.003. Epub 2014 Dec 27.

PMID:
25726146
22.

Enhanced self-administration of alcohol in muscarinic acetylcholine M4 receptor knockout mice.

de la Cour C, Sørensen G, Wortwein G, Weikop P, Dencker D, Fink-Jensen A, Molander A.

Eur J Pharmacol. 2015 Jan 5;746:1-5. doi: 10.1016/j.ejphar.2014.10.050. Epub 2014 Nov 20.

PMID:
25445043
23.

Electroconvulsive stimulation, but not chronic restraint stress, causes structural alterations in adult rat hippocampus--a stereological study.

Olesen MV, Wörtwein G, Pakkenberg B.

Hippocampus. 2015 Jan;25(1):72-80. doi: 10.1002/hipo.22351. Epub 2014 Aug 27.

PMID:
25139647
24.

Neuropeptide Y-stimulated [(35) S]GTPγs functional binding is reduced in the hippocampus after kainate-induced seizures in mice.

Elbrønd-Bek H, Olling JD, Gøtzsche CR, Waterfield A, Wörtwein G, Woldbye DP.

Synapse. 2014 Oct;68(10):427-36. doi: 10.1002/syn.21762. Epub 2014 Jul 9.

PMID:
24985894
25.

Addiction-related effects of DOV 216,303 and cocaine: A comparative study in the mouse.

Sørensen G, Husum H, Brennum LT, Bundgaard C, Montezinho LC, Mørk A, Wörtwein G, Woldbye DP.

Basic Clin Pharmacol Toxicol. 2014 Jun;114(6):451-9. doi: 10.1111/bcpt.12182. Epub 2014 Jan 16.

26.

Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.

Rickhag M, Owens WA, Winkler MT, Strandfelt KN, Rathje M, Sørensen G, Andresen B, Madsen KL, Jørgensen TN, Wörtwein G, Woldbye DP, Sitte H, Daws LC, Gether U.

J Biol Chem. 2013 Sep 20;288(38):27534-44. doi: 10.1074/jbc.M112.441295. Epub 2013 Jul 24.

27.

A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter.

Rickhag M, Hansen FH, Sørensen G, Strandfelt KN, Andresen B, Gotfryd K, Madsen KL, Vestergaard-Klewe I, Ammendrup-Johnsen I, Eriksen J, Newman AH, Füchtbauer EM, Gomeza J, Woldbye DP, Wörtwein G, Gether U.

Nat Commun. 2013;4:1580. doi: 10.1038/ncomms2568. Erratum in: Nat Commun. 2013;4:2589.

28.

Neuropeptide Y Y5 receptor antagonism causes faster extinction and attenuates reinstatement in cocaine-induced place preference.

Sørensen G, Wörtwein G, Fink-Jensen A, Woldbye DP.

Pharmacol Biochem Behav. 2013 Apr;105:151-6. doi: 10.1016/j.pbb.2013.02.010. Epub 2013 Feb 27.

PMID:
23454535
29.

Chronic restraint stress in rats causes sustained increase in urinary corticosterone excretion without affecting cerebral or systemic oxidatively generated DNA/RNA damage.

Jorgensen A, Maigaard K, Wörtwein G, Hageman I, Henriksen T, Weimann A, Møller P, Loft S, Hau J, Poulsen HE, Jorgensen MB.

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jan 10;40:30-7. doi: 10.1016/j.pnpbp.2012.08.016. Epub 2012 Aug 31. Erratum in: Prog Neuropsychopharmacol Biol Psychiatry. 2015 Apr 3;58:105.

PMID:
22960608
30.

An allosteric enhancer of M₄ muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine.

Dencker D, Weikop P, Sørensen G, Woldbye DP, Wörtwein G, Wess J, Fink-Jensen A.

Psychopharmacology (Berl). 2012 Nov;224(2):277-87. doi: 10.1007/s00213-012-2751-8. Epub 2012 May 31.

31.

Electroconvulsive stimulations prevent chronic stress-induced increases in L-type calcium channel mRNAs in the hippocampus and basolateral amygdala.

Maigaard K, Hageman I, Jørgensen A, Jørgensen MB, Wörtwein G.

Neurosci Lett. 2012 May 10;516(1):24-8. doi: 10.1016/j.neulet.2012.03.043. Epub 2012 Mar 24.

PMID:
22465249
32.

Muscarinic Acetylcholine Receptor Subtypes as Potential Drug Targets for the Treatment of Schizophrenia, Drug Abuse and Parkinson's Disease.

Dencker D, Thomsen M, Wörtwein G, Weikop P, Cui Y, Jeon J, Wess J, Fink-Jensen A.

ACS Chem Neurosci. 2012;3(2):80-89.

33.

Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.

Sørensen G, Jensen M, Weikop P, Dencker D, Christiansen SH, Loland CJ, Bengtsen CH, Petersen JH, Fink-Jensen A, Wörtwein G, Woldbye DP.

Psychopharmacology (Berl). 2012 Aug;222(4):565-77. doi: 10.1007/s00213-012-2651-y. Epub 2012 Feb 25.

PMID:
22367168
34.

The effect of subchronic fluoxetine treatment on learning and memory in adolescent rats.

Sass A, Wörtwein G.

Behav Brain Res. 2012 Mar 1;228(1):169-75. doi: 10.1016/j.bbr.2011.12.006. Epub 2011 Dec 9.

PMID:
22178317
35.

Time course and duration of changes in Kv7.2 and Kv11.1 mRNA expression in the hippocampus and piriform cortex following electroconvulsive stimulations.

Hjaeresen ML, Hageman I, Wortwein G, Jørgensen MB.

Brain Stimul. 2012 Jan;5(1):55-60. doi: 10.1016/j.brs.2011.01.008. Epub 2011 Feb 26.

PMID:
22037135
36.

Increased numbers of orexin/hypocretin neurons in a genetic rat depression model.

Mikrouli E, Wörtwein G, Soylu R, Mathé AA, Petersén Å.

Neuropeptides. 2011 Dec;45(6):401-6. doi: 10.1016/j.npep.2011.07.010. Epub 2011 Aug 25.

PMID:
21871662
37.

Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1/M4 preferring muscarinic receptor agonist xanomeline.

Dencker D, Wörtwein G, Weikop P, Jeon J, Thomsen M, Sager TN, Mørk A, Woldbye DP, Wess J, Fink-Jensen A.

J Neurosci. 2011 Apr 20;31(16):5905-8. doi: 10.1523/JNEUROSCI.0370-11.2011.

38.

Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice.

Schmidt LS, Thomsen M, Weikop P, Dencker D, Wess J, Woldbye DP, Wortwein G, Fink-Jensen A.

Psychopharmacology (Berl). 2011 Aug;216(3):367-78. doi: 10.1007/s00213-011-2225-4. Epub 2011 Mar 5.

39.

Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor.

Fink-Jensen A, Schmidt LS, Dencker D, Schülein C, Wess J, Wörtwein G, Woldbye DP.

Eur J Pharmacol. 2011 Apr 10;656(1-3):39-44. doi: 10.1016/j.ejphar.2011.01.018. Epub 2011 Jan 24.

40.

Pharmacological characterization of social isolation-induced hyperactivity.

Fabricius K, Helboe L, Fink-Jensen A, Wörtwein G, Steiniger-Brach B.

Psychopharmacology (Berl). 2011 May;215(2):257-66. doi: 10.1007/s00213-010-2128-9. Epub 2010 Dec 31.

PMID:
21193984
41.

Socially isolated rats exhibit changes in dopamine homeostasis pertinent to schizophrenia.

Fabricius K, Steiniger-Brach B, Helboe L, Fink-Jensen A, Wörtwein G.

Int J Dev Neurosci. 2011 May;29(3):347-50. doi: 10.1016/j.ijdevneu.2010.09.003. Epub 2010 Sep 25.

PMID:
20884342
42.

Fluoxetine reverts chronic restraint stress-induced depression-like behaviour and increases neuropeptide Y and galanin expression in mice.

Christiansen SH, Olesen MV, Wörtwein G, Woldbye DP.

Behav Brain Res. 2011 Jan 20;216(2):585-91. doi: 10.1016/j.bbr.2010.08.044. Epub 2010 Sep 15.

PMID:
20816900
43.

Increased dopaminergic activity in socially isolated rats: an electrophysiological study.

Fabricius K, Helboe L, Fink-Jensen A, Wörtwein G, Steiniger-Brach B, Sotty F.

Neurosci Lett. 2010 Sep 27;482(2):117-22. doi: 10.1016/j.neulet.2010.07.014. Epub 2010 Jul 15.

PMID:
20637831
44.

A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors.

Jeon J, Dencker D, Wörtwein G, Woldbye DP, Cui Y, Davis AA, Levey AI, Schütz G, Sager TN, Mørk A, Li C, Deng CX, Fink-Jensen A, Wess J.

J Neurosci. 2010 Feb 10;30(6):2396-405. doi: 10.1523/JNEUROSCI.3843-09.2010.

45.

Increased amphetamine-induced locomotor activity, sensitization, and accumbal dopamine release in M5 muscarinic receptor knockout mice.

Schmidt LS, Miller AD, Lester DB, Bay-Richter C, Schülein C, Frikke-Schmidt H, Wess J, Blaha CD, Woldbye DP, Fink-Jensen A, Wortwein G.

Psychopharmacology (Berl). 2010 Jan;207(4):547-58. doi: 10.1007/s00213-009-1685-2. Epub 2009 Oct 10.

46.

Neuropeptide Y infusion into the shell region of the rat nucleus accumbens increases extracellular levels of dopamine.

Sørensen G, Wegener G, Hasselstrøm J, Hansen TV, Wörtwein G, Fink-Jensen A, Woldbye DP.

Neuroreport. 2009 Jul 15;20(11):1023-6.

PMID:
19579268
47.

Nortriptyline mediates behavioral effects without affecting hippocampal cytogenesis in a genetic rat depression model.

Petersén A, Wörtwein G, Gruber SH, El-Khoury A, Mathé AA.

Neurosci Lett. 2009 Feb 20;451(2):148-51. doi: 10.1016/j.neulet.2008.12.046. Epub 2008 Dec 27.

PMID:
19135130
48.

Electroconvulsive stimulations normalizes stress-induced changes in the glucocorticoid receptor and behaviour.

Hageman I, Nielsen M, Wortwein G, Diemer NH, Jorgensen MB.

Behav Brain Res. 2009 Jan 3;196(1):71-7. doi: 10.1016/j.bbr.2008.07.037. Epub 2008 Aug 5.

PMID:
18725247
49.

Effects of acute and chronic aripiprazole treatment on choice between cocaine self-administration and food under a concurrent schedule of reinforcement in rats.

Thomsen M, Fink-Jensen A, Woldbye DP, Wörtwein G, Sager TN, Holm R, Pepe LM, Caine SB.

Psychopharmacology (Berl). 2008 Nov;201(1):43-53. doi: 10.1007/s00213-008-1245-1. Epub 2008 Jul 9.

50.

Electroconvulsive stimulations prevent stress-induced morphological changes in the hippocampus.

Hageman I, Nielsen M, Wortwein G, Diemer NH, Jorgensen MB.

Stress. 2008 Jul;11(4):282-9. doi: 10.1080/10253890701783794.

PMID:
18574788

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