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Items: 1 to 50 of 350

1.

The do's, don'ts and don't knows of establishing a sustainable longitudinal integrated clerkship.

Bartlett M, Couper I, Poncelet A, Worley P.

Perspect Med Educ. 2020 Feb;9(1):5-19. doi: 10.1007/s40037-019-00558-z.

PMID:
31953655
2.

Synaptic biomarkers in CSF aid in diagnosis, correlate with cognition and predict progression in MCI and Alzheimer's disease.

Galasko D, Xiao M, Xu D, Smirnov D, Salmon DP, Dewit N, Vanbrabant J, Jacobs D, Vanderstichele H, Vanmechelen E; Alzheimer's Disease Neuroimaging Initiative (ADNI), Worley P.

Alzheimers Dement (N Y). 2019 Dec 9;5:871-882. doi: 10.1016/j.trci.2019.11.002. eCollection 2019.

3.

Call to expand teaching opportunities in rural family medicine.

Walters L, Worley P.

Med Educ. 2020 Feb;54(2):97-99. doi: 10.1111/medu.14042. No abstract available.

PMID:
31800115
4.

LanCL1 promotes motor neuron survival and extends the lifespan of amyotrophic lateral sclerosis mice.

Tan H, Chen M, Pang D, Xia X, Du C, Yang W, Cui Y, Huang C, Jiang W, Bi D, Li C, Shang H, Worley PF, Xiao B.

Cell Death Differ. 2019 Sep 30. doi: 10.1038/s41418-019-0422-6. [Epub ahead of print]

PMID:
31570855
5.

Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling.

Chokshi V, Gao M, Grier BD, Owens A, Wang H, Worley PF, Lee HK.

Neuron. 2019 Nov 20;104(4):736-748.e6. doi: 10.1016/j.neuron.2019.08.017. Epub 2019 Sep 25.

PMID:
31563294
6.

From locum-led outposts to locally led continuous rural training networks: the National Rural Generalist Pathway.

Worley PS, O'Sullivan B, Ellis R.

Med J Aust. 2019 Jul;211(2):57-59.e1. doi: 10.5694/mja2.50225. Epub 2019 Jun 28. No abstract available.

PMID:
31250926
7.

Resting-State Functional Connectivity Is Associated With Cerebrospinal Fluid Levels of the Synaptic Protein NPTX2 in Non-demented Older Adults.

Soldan A, Moghekar A, Walker KA, Pettigrew C, Hou X, Lu H, Miller MI, Alfini A, Albert M, Xu D, Xiao MF, Worley P; BIOCARD Research Team.

Front Aging Neurosci. 2019 Jun 7;11:132. doi: 10.3389/fnagi.2019.00132. eCollection 2019.

8.

Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation.

Zhang W, Chuang YA, Na Y, Ye Z, Yang L, Lin R, Zhou J, Wu J, Qiu J, Savonenko A, Leahy DJ, Huganir R, Linden DJ, Worley PF.

Mol Cell. 2019 Jul 11;75(1):13-25.e5. doi: 10.1016/j.molcel.2019.05.004. Epub 2019 May 28.

PMID:
31151856
9.

The Northern Territory Medical Program - growing our own in the NT.

Worley P, Lowe M, Notaras L, Strasser S, Kidd M, Slee M, Williams R, Noutsos T, Wakerman J.

Rural Remote Health. 2019 May;19(2):4671. doi: 10.22605/RRH4671. Epub 2019 May 27.

10.

Vitamin D increases glucocorticoid efficacy via inhibition of mTORC1 in experimental models of multiple sclerosis.

Hoepner R, Bagnoud M, Pistor M, Salmen A, Briner M, Synn H, Schrewe L, Guse K, Ahmadi F, Demir S, Laverick L, Gresle M, Worley P, Reichardt HM, Butzkueven H, Gold R, Metz I, Lühder F, Chan A.

Acta Neuropathol. 2019 Sep;138(3):443-456. doi: 10.1007/s00401-019-02018-8. Epub 2019 Apr 27.

11.

Homer1a Is Required for Establishment of Contralateral Bias and Maintenance of Ocular Dominance in Mouse Visual Cortex.

Chokshi V, Druciak B, Worley PF, Lee HK.

J Neurosci. 2019 May 15;39(20):3897-3905. doi: 10.1523/JNEUROSCI.3188-18.2019. Epub 2019 Mar 13.

12.

Increased Alcohol-Drinking Induced by Manipulations of mGlu5 Phosphorylation within the Bed Nucleus of the Stria Terminalis.

Campbell RR, Domingo RD, Williams AR, Wroten MG, McGregor HA, Waltermire RS, Greentree DI, Goulding SP, Thompson AB, Lee KM, Quadir SG, Jimenez Chavez CL, Coelho MA, Gould AT, von Jonquieres G, Klugmann M, Worley PF, Kippin TE, Szumlinski KK.

J Neurosci. 2019 Apr 3;39(14):2745-2761. doi: 10.1523/JNEUROSCI.1909-18.2018. Epub 2019 Feb 8.

13.

Leasing a medical curriculum: What's it worth?

Prideaux D, Ash J, Broadley S, Crotty B, Hart W, Searle J, Watson J, Wing L, Worley P.

Med Teach. 2019 Jun;41(6):697-702. doi: 10.1080/0142159X.2018.1563290. Epub 2019 Feb 8.

PMID:
30736709
14.

Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy.

Thannickal TC, John J, Shan L, Swaab DF, Wu MF, Ramanathan L, McGregor R, Chew KT, Cornford M, Yamanaka A, Inutsuka A, Fronczek R, Lammers GJ, Worley PF, Siegel JM.

Sci Transl Med. 2018 Jun 27;10(447). pii: eaao4953. doi: 10.1126/scitranslmed.aao4953.

PMID:
29950444
15.

Clinical and Diagnostic Significance of Homer1 in hepatitis B virus-induced Hepatocellular Carcinoma.

Luo P, Feng X, Jing W, Zhu M, Li N, Zhou H, Worley PF, Chai H, Tu J.

J Cancer. 2018 Jan 11;9(4):683-689. doi: 10.7150/jca.22279. eCollection 2018.

16.

Delayed Degradation and Impaired Dendritic Delivery of Intron-Lacking EGFP-Arc/Arg3.1 mRNA in EGFP-Arc Transgenic Mice.

Steward O, Matsudaira Yee K, Farris S, Pirbhoy PS, Worley P, Okamura K, Okuno H, Bito H.

Front Mol Neurosci. 2018 Jan 31;10:435. doi: 10.3389/fnmol.2017.00435. eCollection 2017.

17.

Why do we persist with teaching students in antagonistic unrepresentative learning environments?

Worley P.

Educ Prim Care. 2018 Jan;29(1):11-12. doi: 10.1080/14739879.2017.1416494. No abstract available.

PMID:
29400644
18.

FRMPD4 mutations cause X-linked intellectual disability and disrupt dendritic spine morphogenesis.

Piard J, Hu JH, Campeau PM, Rzonca S, Van Esch H, Vincent E, Han M, Rossignol E, Castaneda J, Chelly J, Skinner C, Kalscheuer VM, Wang R, Lemyre E, Kosinska J, Stawinski P, Bal J, Hoffman DA, Schwartz CE, Van Maldergem L, Wang T, Worley PF.

Hum Mol Genet. 2018 Feb 15;27(4):589-600. doi: 10.1093/hmg/ddx426.

19.

Distinct roles of Rheb and Raptor in activating mTOR complex 1 for the self-renewal of hematopoietic stem cells.

Peng H, Kasada A, Ueno M, Hoshii T, Tadokoro Y, Nomura N, Ito C, Takase Y, Vu HT, Kobayashi M, Xiao B, Worley PF, Hirao A.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1129-1135. doi: 10.1016/j.bbrc.2017.11.140. Epub 2017 Nov 22.

PMID:
29175333
20.

Behavioral and Neurochemical Phenotyping of Mice Incapable of Homer1a Induction.

Datko MC, Hu JH, Williams M, Reyes CM, Lominac KD, von Jonquieres G, Klugmann M, Worley PF, Szumlinski KK.

Front Behav Neurosci. 2017 Nov 1;11:208. doi: 10.3389/fnbeh.2017.00208. eCollection 2017.

21.

Narp Mediates Antidepressant-Like Effects of Electroconvulsive Seizures.

Chang AD, Vaidya PV, Retzbach EP, Chung SJ, Kim U, Baselice K, Maynard K, Stepanian A, Staley M, Xiao L, Blouin A, Han S, Lee J, Worley PF, Tamashiro KL, Hempstead BL, Martinowich K, Ann Wilson M, Baraban JM, Reti IM.

Neuropsychopharmacology. 2018 Apr;43(5):1088-1098. doi: 10.1038/npp.2017.252. Epub 2017 Oct 20.

22.

Medical education research should extend further into clinical practice.

Teodorczuk A, Yardley S, Patel R, Rogers GD, Billett S, Worley P, Hirsh D, Illing J.

Med Educ. 2017 Nov;51(11):1098-1100. doi: 10.1111/medu.13459. No abstract available.

PMID:
29024150
23.

mTORC1 loss impairs epidermal adhesion via TGF-β/Rho kinase activation.

Asrani K, Sood A, Torres A, Georgess D, Phatak P, Kaur H, Dubin A, Talbot CC Jr, Elhelu L, Ewald AJ, Xiao B, Worley P, Lotan TL.

J Clin Invest. 2017 Nov 1;127(11):4001-4017. doi: 10.1172/JCI92893. Epub 2017 Sep 25.

24.

STIM1 Regulates Somatic Ca2+ Signals and Intrinsic Firing Properties of Cerebellar Purkinje Neurons.

Ryu C, Jang DC, Jung D, Kim YG, Shim HG, Ryu HH, Lee YS, Linden DJ, Worley PF, Kim SJ.

J Neurosci. 2017 Sep 13;37(37):8876-8894. doi: 10.1523/JNEUROSCI.3973-16.2017. Epub 2017 Aug 11.

25.

Exposure to complex environments results in more sparse representations of space in the hippocampus.

Bilkey DK, Cheyne KR, Eckert MJ, Lu X, Chowdhury S, Worley PF, Crandall JE, Abraham WC.

Hippocampus. 2017 Nov;27(11):1178-1191. doi: 10.1002/hipo.22762. Epub 2017 Jul 21.

26.

NPTX2 and cognitive dysfunction in Alzheimer's Disease.

Xiao MF, Xu D, Craig MT, Pelkey KA, Chien CC, Shi Y, Zhang J, Resnick S, Pletnikova O, Salmon D, Brewer J, Edland S, Wegiel J, Tycko B, Savonenko A, Reeves RH, Troncoso JC, McBain CJ, Galasko D, Worley PF.

Elife. 2017 Mar 23;6. pii: e23798. doi: 10.7554/eLife.23798.

27.

Orai1-Mediated Antimicrobial Secretion from Pancreatic Acini Shapes the Gut Microbiome and Regulates Gut Innate Immunity.

Ahuja M, Schwartz DM, Tandon M, Son A, Zeng M, Swaim W, Eckhaus M, Hoffman V, Cui Y, Xiao B, Worley PF, Muallem S.

Cell Metab. 2017 Mar 7;25(3):635-646. doi: 10.1016/j.cmet.2017.02.007.

28.

Increased Sparsity of Hippocampal CA1 Neuronal Ensembles in a Mouse Model of Down Syndrome Assayed by Arc Expression.

Smith-Hicks CL, Cai P, Savonenko AV, Reeves RH, Worley PF.

Front Neural Circuits. 2017 Feb 3;11:6. doi: 10.3389/fncir.2017.00006. eCollection 2017.

29.

Dynamic Regulation of Homer Binding to Group I Metabotropic Glutamate Receptors by Preso1 and Converging Kinase Cascades.

Hu JH, Worley PF, Kammermeier PJ.

J Pharmacol Exp Ther. 2017 Apr;361(1):122-129. doi: 10.1124/jpet.116.238394. Epub 2017 Feb 8.

30.

Homer1a drives homeostatic scaling-down of excitatory synapses during sleep.

Diering GH, Nirujogi RS, Roth RH, Worley PF, Pandey A, Huganir RL.

Science. 2017 Feb 3;355(6324):511-515. doi: 10.1126/science.aai8355. Epub 2017 Feb 2.

31.

Student academic performance in rural clinical schools: The impact of cohort size and competition.

Condon BP, Worley PS, Condon JR, Prideaux DJ.

Med Teach. 2017 Mar;39(3):262-268. doi: 10.1080/0142159X.2017.1270430. Epub 2016 Dec 30.

PMID:
28033729
32.

TRIAD3/RNF216 mutations associated with Gordon Holmes syndrome lead to synaptic and cognitive impairments via Arc misregulation.

Husain N, Yuan Q, Yen YC, Pletnikova O, Sally DQ, Worley P, Bichler Z, Shawn Je H.

Aging Cell. 2017 Apr;16(2):281-292. doi: 10.1111/acel.12551. Epub 2016 Dec 20.

33.

Reduced superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with early psychosis in association with clinical features.

Coughlin JM, Hayes LN, Tanaka T, Xiao M, Yolken RH, Worley P, Leweke FM, Sawa A.

Schizophr Res. 2017 May;183:64-69. doi: 10.1016/j.schres.2016.10.040. Epub 2016 Nov 23.

PMID:
27889384
34.

Sensitivity to isoflurane anesthesia increases in autism spectrum disorder Shank3+/∆c mutant mouse model.

Li C, Schaefer M, Gray C, Yang Y, Furmanski O, Liu S, Worley P, Mintz CD, Tao F, Johns RA.

Neurotoxicol Teratol. 2017 Mar - Apr;60:69-74. doi: 10.1016/j.ntt.2016.11.002. Epub 2016 Nov 14.

35.
36.

A typology of longitudinal integrated clerkships.

Worley P, Couper I, Strasser R, Graves L, Cummings BA, Woodman R, Stagg P, Hirsh D; Consortium of Longitudinal Integrated Clerkships (CLIC) Research Collaborative.

Med Educ. 2016 Sep;50(9):922-32. doi: 10.1111/medu.13084.

PMID:
27562892
37.

Training for impact: the socio-economic impact of a fit for purpose health workforce on communities.

Pálsdóttir B, Barry J, Bruno A, Barr H, Clithero A, Cobb N, De Maeseneer J, Kiguli-Malwadde E, Neusy AJ, Reeves S, Strasser R, Worley P.

Hum Resour Health. 2016 Aug 15;14(1):49. doi: 10.1186/s12960-016-0143-6.

38.

Real-Time Imaging Reveals Properties of Glutamate-Induced Arc/Arg 3.1 Translation in Neuronal Dendrites.

Na Y, Park S, Lee C, Kim DK, Park JM, Sockanathan S, Huganir RL, Worley PF.

Neuron. 2016 Aug 3;91(3):561-73. doi: 10.1016/j.neuron.2016.06.017. Epub 2016 Jul 7.

39.

Global sharing, local innovation: Four schools, four countries, one curriculum.

Castelo-Branco L, Finucane P, Marvão P, McCrorie P, Ponte J, Worley P.

Med Teach. 2016 Dec;38(12):1204-1208. Epub 2016 Jun 1.

PMID:
27248161
40.

Pentraxins Coordinate Excitatory Synapse Maturation and Circuit Integration of Parvalbumin Interneurons.

Pelkey KA, Barksdale E, Craig MT, Yuan X, Sukumaran M, Vargish GA, Mitchell RM, Wyeth MS, Petralia RS, Chittajallu R, Karlsson RM, Cameron HA, Murata Y, Colonnese MT, Worley PF, McBain CJ.

Neuron. 2016 May 4;90(3):661. doi: 10.1016/j.neuron.2016.04.024. No abstract available.

41.

Gastric Schwannoma.

Kinsey-Trotman S, Balalis G, Gupta A, Worley P.

J Gastrointest Surg. 2016 Sep;20(9):1666-8. doi: 10.1007/s11605-016-3122-2. Epub 2016 Mar 8. No abstract available.

PMID:
26956006
42.

Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice.

Guo W, Molinaro G, Collins KA, Hays SA, Paylor R, Worley PF, Szumlinski KK, Huber KM.

J Neurosci. 2016 Feb 17;36(7):2131-47. doi: 10.1523/JNEUROSCI.2921-15.2016.

43.

Metabotropic Glutamate Receptors Induce a Form of LTP Controlled by Translation and Arc Signaling in the Hippocampus.

Wang H, Ardiles AO, Yang S, Tran T, Posada-Duque R, Valdivia G, Baek M, Chuang YA, Palacios AG, Gallagher M, Worley P, Kirkwood A.

J Neurosci. 2016 Feb 3;36(5):1723-9. doi: 10.1523/JNEUROSCI.0878-15.2016.

44.

Definition of a Bidirectional Activity-Dependent Pathway Involving BDNF and Narp.

Mariga A, Glaser J, Mathias L, Xu D, Xiao M, Worley P, Ninan I, Chao MV.

Cell Rep. 2015 Dec 1;13(9):1747-56. doi: 10.1016/j.celrep.2015.10.064. Epub 2015 Nov 19.

45.

Altered NMDA receptor function in primary cultures of hippocampal neurons from mice lacking the Homer2 gene.

Smothers CT, Szumlinski KK, Worley PF, Woodward JJ.

Synapse. 2016 Jan;70(1):33-9. doi: 10.1002/syn.21869. Epub 2015 Oct 15.

46.

Homer 1a and mGluR5 phosphorylation in reward-sensitive metaplasticity: A hypothesis of neuronal selection and bidirectional synaptic plasticity.

Marton TM, Hussain Shuler MG, Worley PF.

Brain Res. 2015 Dec 2;1628(Pt A):17-28. doi: 10.1016/j.brainres.2015.06.037. Epub 2015 Jul 14. Review.

PMID:
26187757
47.

Cerebellar associative sensory learning defects in five mouse autism models.

Kloth AD, Badura A, Li A, Cherskov A, Connolly SG, Giovannucci A, Bangash MA, Grasselli G, Peñagarikano O, Piochon C, Tsai PT, Geschwind DH, Hansel C, Sahin M, Takumi T, Worley PF, Wang SS.

Elife. 2015 Jul 9;4:e06085. doi: 10.7554/eLife.06085.

48.

Putting communities in the driver's seat: the realities of community-engaged medical education.

Strasser R, Worley P, Cristobal F, Marsh DC, Berry S, Strasser S, Ellaway R.

Acad Med. 2015 Nov;90(11):1466-70. doi: 10.1097/ACM.0000000000000765.

PMID:
26017354
49.

Structural basis of arc binding to synaptic proteins: implications for cognitive disease.

Zhang W, Wu J, Ward MD, Yang S, Chuang YA, Xiao M, Li R, Leahy DJ, Worley PF.

Neuron. 2015 Apr 22;86(2):490-500. doi: 10.1016/j.neuron.2015.03.030. Epub 2015 Apr 9.

50.

Protein Kinase C Epsilon Activity in the Nucleus Accumbens and Central Nucleus of the Amygdala Mediates Binge Alcohol Consumption.

Cozzoli DK, Courson J, Rostock C, Campbell RR, Wroten MG, McGregor H, Caruana AL, Miller BW, Hu JH, Wu Zhang P, Xiao B, Worley PF, Crabbe JC, Finn DA, Szumlinski KK.

Biol Psychiatry. 2016 Mar 15;79(6):443-51. doi: 10.1016/j.biopsych.2015.01.019. Epub 2015 Mar 5.

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