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Items: 29

1.

Pomalidomide and lenalidomide induce p21 WAF-1 expression in both lymphoma and multiple myeloma through a LSD1-mediated epigenetic mechanism.

Escoubet-Lozach L, Lin IL, Jensen-Pergakes K, Brady HA, Gandhi AK, Schafer PH, Muller GW, Worland PJ, Chan KW, Verhelle D.

Cancer Res. 2009 Sep 15;69(18):7347-56. doi: 10.1158/0008-5472.CAN-08-4898. Epub 2009 Sep 8.

2.

Spiculated periosteal response induced by intraosseous injection of 22Rv1 prostate cancer cells resembles subset of bone metastases in prostate cancer patients.

Henry MD, Silva MD, Wen S, Siebert E, Solin E, Chandra S, Worland PJ.

Prostate. 2005 Dec 1;65(4):347-54.

PMID:
16032708
3.

A prostate-specific membrane antigen-targeted monoclonal antibody-chemotherapeutic conjugate designed for the treatment of prostate cancer.

Henry MD, Wen S, Silva MD, Chandra S, Milton M, Worland PJ.

Cancer Res. 2004 Nov 1;64(21):7995-8001.

4.

Anticancer antibodies.

Ross JS, Gray K, Gray GS, Worland PJ, Rolfe M.

Am J Clin Pathol. 2003 Apr;119(4):472-85. Review.

PMID:
12710120
5.

Antibody-based therapeutics in oncology.

Ross J, Gray K, Schenkein D, Greene B, Gray GS, Shulok J, Worland PJ, Celniker A, Rolfe M.

Expert Rev Anticancer Ther. 2003 Feb;3(1):107-21. Review.

PMID:
12597355
6.

Structure-activity relationship studies of flavopiridol analogues.

Murthi KK, Dubay M, McClure C, Brizuela L, Boisclair MD, Worland PJ, Mansuri MM, Pal K.

Bioorg Med Chem Lett. 2000 May 15;10(10):1037-41.

PMID:
10843211
7.

Down-regulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol.

Carlson B, Lahusen T, Singh S, Loaiza-Perez A, Worland PJ, Pestell R, Albanese C, Sausville EA, Senderowicz AM.

Cancer Res. 1999 Sep 15;59(18):4634-41.

8.

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA, O'Connor PM.

J Natl Cancer Inst. 1996 Jul 17;88(14):956-65.

PMID:
8667426
9.

Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells.

Carlson BA, Dubay MM, Sausville EA, Brizuela L, Worland PJ.

Cancer Res. 1996 Jul 1;56(13):2973-8.

10.

Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

De Azevedo WF Jr, Mueller-Dieckmann HJ, Schulze-Gahmen U, Worland PJ, Sausville E, Kim SH.

Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2735-40.

12.

Apoptosis in 7-hydroxystaurosporine-treated T lymphoblasts correlates with activation of cyclin-dependent kinases 1 and 2.

Wang Q, Worland PJ, Clark JL, Carlson BA, Sausville EA.

Cell Growth Differ. 1995 Aug;6(8):927-36. Erratum in: Cell Growth Differ 1995 Oct;6(10):1339.

13.

The gastrin-releasing peptide receptor is rapidly phosphorylated by a kinase other than protein kinase C after exposure to agonist.

Kroog GS, Sainz E, Worland PJ, Akeson MA, Benya RV, Jensen RT, Battey JF.

J Biol Chem. 1995 Apr 7;270(14):8217-24.

14.

Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.

Losiewicz MD, Carlson BA, Kaur G, Sausville EA, Worland PJ.

Biochem Biophys Res Commun. 1994 Jun 15;201(2):589-95.

PMID:
8002990
15.

Differential inhibition of protein kinase C isozymes by UCN-01, a staurosporine analogue.

Seynaeve CM, Kazanietz MG, Blumberg PM, Sausville EA, Worland PJ.

Mol Pharmacol. 1994 Jun;45(6):1207-14.

PMID:
8022414
16.

Alteration of the phosphorylation state of p34cdc2 kinase by the flavone L86-8275 in breast carcinoma cells. Correlation with decreased H1 kinase activity.

Worland PJ, Kaur G, Stetler-Stevenson M, Sebers S, Sartor O, Sausville EA.

Biochem Pharmacol. 1993 Nov 17;46(10):1831-40.

PMID:
8250970
17.

Cell cycle arrest and growth inhibition by the protein kinase antagonist UCN-01 in human breast carcinoma cells.

Seynaeve CM, Stetler-Stevenson M, Sebers S, Kaur G, Sausville EA, Worland PJ.

Cancer Res. 1993 May 1;53(9):2081-6.

18.

Expression of growth-related genes during tumor progression in v-raf-transformed rat liver epithelial cells.

Hampton LL, Worland PJ, Yu B, Thorgeirsson SS, Huggett AC.

Cancer Res. 1990 Dec 1;50(23):7460-7.

20.

Structure and function of suppressor tRNAs in higher eukaryotes.

Hatfield DL, Smith DW, Lee BJ, Worland PJ, Oroszlan S.

Crit Rev Biochem Mol Biol. 1990;25(2):71-96. Review. No abstract available.

PMID:
2183969
21.

Identification of a selenocysteyl-tRNA(Ser) in mammalian cells that recognizes the nonsense codon, UGA.

Lee BJ, Worland PJ, Davis JN, Stadtman TC, Hatfield DL.

J Biol Chem. 1989 Jun 15;264(17):9724-7.

22.

Secreted and cellular polypeptide patterns of MCF-7 human breast cancer cells following either estrogen stimulation or v-H-ras transfection.

Worland PJ, Bronzert D, Dickson RB, Lippman ME, Hampton L, Thorgeirsson SS, Wirth PJ.

Cancer Res. 1989 Jan 1;49(1):51-7.

23.

Medial prefrontal cortical lesions modulate baroreflex sensitivity in the rat.

Verberne AJ, Lewis SJ, Worland PJ, Beart PM, Jarrott B, Christie MJ, Louis WJ.

Brain Res. 1987 Nov 24;426(2):243-9.

PMID:
3319045
24.

Radioimmunoassay for the quantitation of lisinopril and enalaprilat.

Worland PJ, Jarrott B.

J Pharm Sci. 1986 May;75(5):512-6.

PMID:
3016233
25.
26.

An in situ gastric pouch technique for direct measurement of the gastric absorption of drugs in the rat.

Worland PJ, Drummer OH, Jarrott B.

J Pharmacol Methods. 1983 Nov;10(3):215-21.

PMID:
6656264
27.

Intestinal contribution to the presystemic elimination of beta-phenethylamine in the rat.

Worland PJ, Ilett KF.

J Pharm Pharmacol. 1983 Oct;35(10):636-40.

PMID:
6139431
28.

Tissue distribution of captopril, reducible captopril conjugates and S-methylcaptopril in the rat.

Drummer OH, Worland PJ, Jarrott B.

Biochem Pharmacol. 1983 May 15;32(10):1563-8.

PMID:
6344870
29.

Potentiation of human vascular smooth muscle contraction by angiotensin.

Moulds RF, Worland PJ.

J Cardiovasc Pharmacol. 1980 Jul-Aug;2(4):377-86. No abstract available.

PMID:
6156336

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