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Items: 39

1.

High-Affinity Nucleic-Acid-Based Receptors for Steroids.

Yang KA, Chun H, Zhang Y, Pecic S, Nakatsuka N, Andrews AM, Worgall TS, Stojanovic MN.

ACS Chem Biol. 2017 Dec 15;12(12):3103-3112. doi: 10.1021/acschembio.7b00634. Epub 2017 Nov 22.

2.

Distinct Serum Sphingolipid Profiles among School-aged Children with Exercise-induced Wheeze and Asthma Persistence.

Perzanowski MS, Ono JG, Acosta LM, Kim BI, Divjan A, Miller R, Rundle A, Worgall S, Worgall TS.

Am J Respir Crit Care Med. 2017 Apr 15;195(8):1068-1070. doi: 10.1164/rccm.201609-1884LE. No abstract available.

3.
4.

Sphingolipids, ORMDL3 and asthma: what is the evidence?

Worgall TS.

Curr Opin Clin Nutr Metab Care. 2017 Mar;20(2):99-103. doi: 10.1097/MCO.0000000000000349. Review.

PMID:
28030368
5.

Liver serine palmitoyltransferase activity deficiency in early life impairs adherens junctions and promotes tumorigenesis.

Li Z, Kabir I, Jiang H, Zhou H, Libien J, Zeng J, Stanek A, Ou P, Li KR, Zhang S, Bui HH, Kuo MS, Park TS, Kim B, Worgall TS, Huan C, Jiang XC.

Hepatology. 2016 Dec;64(6):2089-2102. doi: 10.1002/hep.28845.

6.

Airway Epithelial Cell Release of GABA is Regulated by Protein Kinase A.

Danielsson J, Zaidi S, Kim B, Funayama H, Yim PD, Xu D, Worgall TS, Gallos G, Emala CW.

Lung. 2016 Jun;194(3):401-8. doi: 10.1007/s00408-016-9867-2. Epub 2016 Mar 17.

7.

Airway reactivity and sphingolipids-implications for childhood asthma.

Ono JG, Worgall TS, Worgall S.

Mol Cell Pediatr. 2015 Dec;2(1):13. doi: 10.1186/s40348-015-0025-3. Epub 2015 Dec 4.

8.

Low serum sphingolipids in children with attention deficit-hyperactivity disorder.

Henríquez-Henríquez MP, Solari S, Quiroga T, Kim BI, Deckelbaum RJ, Worgall TS.

Front Neurosci. 2015 Aug 25;9:300. doi: 10.3389/fnins.2015.00300. eCollection 2015.

9.

Profiling the Essential Nature of Lipid Metabolism in Asexual Blood and Gametocyte Stages of Plasmodium falciparum.

Gulati S, Ekland EH, Ruggles KV, Chan RB, Jayabalasingham B, Zhou B, Mantel PY, Lee MC, Spottiswoode N, Coburn-Flynn O, Hjelmqvist D, Worgall TS, Marti M, Di Paolo G, Fidock DA.

Cell Host Microbe. 2015 Sep 9;18(3):371-81. doi: 10.1016/j.chom.2015.08.003.

10.

Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors.

Yang KA, Barbu M, Halim M, Pallavi P, Kim B, Kolpashchikov DM, Pecic S, Taylor S, Worgall TS, Stojanovic MN.

Nat Chem. 2014 Nov;6(11):1003-8. doi: 10.1038/nchem.2058. Epub 2014 Sep 28.

11.

17q21 locus and ORMDL3: an increased risk for childhood asthma.

Ono JG, Worgall TS, Worgall S.

Pediatr Res. 2014 Jan;75(1-2):165-70. doi: 10.1038/pr.2013.186. Epub 2013 Oct 28. Review.

PMID:
24165737
12.

Impaired sphingolipid synthesis in the respiratory tract induces airway hyperreactivity.

Worgall TS, Veerappan A, Sung B, Kim BI, Weiner E, Bholah R, Silver RB, Jiang XC, Worgall S.

Sci Transl Med. 2013 May 22;5(186):186ra67. doi: 10.1126/scitranslmed.3005765. Erratum in: Sci Transl Med. 2013 Jul 3;5(192):192er7.

13.

Low sphingosine-1-phosphate impairs lung dendritic cells in cystic fibrosis.

Xu Y, Krause A, Limberis M, Worgall TS, Worgall S.

Am J Respir Cell Mol Biol. 2013 Feb;48(2):250-7. doi: 10.1165/rcmb.2012-0021OC. Epub 2012 Dec 13.

14.

Sphingolipids and atherosclerosis.

Hornemann T, Worgall TS.

Atherosclerosis. 2013 Jan;226(1):16-28. doi: 10.1016/j.atherosclerosis.2012.08.041. Epub 2012 Sep 29. Review.

PMID:
23075523
15.

Fatty acids regulate endothelial lipase and inflammatory markers in macrophages and in mouse aorta: a role for PPARγ.

Jung UJ, Torrejon C, Chang CL, Hamai H, Worgall TS, Deckelbaum RJ.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2929-37. doi: 10.1161/ATVBAHA.112.300188. Epub 2012 Oct 4.

16.

Sphingolipid synthetic pathways are major regulators of lipid homeostasis.

Worgall TS.

Adv Exp Med Biol. 2011;721:139-48. doi: 10.1007/978-1-4614-0650-1_9. Review.

PMID:
21910087
17.

Detecting hydrophobic molecules with nucleic acid-based receptors.

Stojanovic MN, Worgall TS.

Curr Opin Chem Biol. 2010 Dec;14(6):751-7. doi: 10.1016/j.cbpa.2010.07.008. Epub 2010 Aug 19. Review.

PMID:
20727817
18.

Lipoprotein patterns in adult cystic fibrosis: a cause for concern or marker for survival?

Worgall TS.

Respirology. 2010 Jul;15(5):731-2. doi: 10.1111/j.1440-1843.2010.01788.x. No abstract available.

PMID:
20653919
19.

Proinflammatory phenotype and increased caveolin-1 in alveolar macrophages with silenced CFTR mRNA.

Xu Y, Krause A, Hamai H, Harvey BG, Worgall TS, Worgall S.

PLoS One. 2010 Jun 8;5(6):e11004. doi: 10.1371/journal.pone.0011004.

20.

Lipid metabolism in cystic fibrosis.

Worgall TS.

Curr Opin Clin Nutr Metab Care. 2009 Mar;12(2):105-9. Review.

PMID:
19209467
21.

n-3 fatty acids reduce arterial LDL-cholesterol delivery and arterial lipoprotein lipase levels and lipase distribution.

Chang CL, Seo T, Matsuzaki M, Worgall TS, Deckelbaum RJ.

Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):555-61. doi: 10.1161/ATVBAHA.108.182287. Epub 2009 Feb 5.

22.

Defective CFTR increases synthesis and mass of sphingolipids that modulate membrane composition and lipid signaling.

Hamai H, Keyserman F, Quittell LM, Worgall TS.

J Lipid Res. 2009 Jun;50(6):1101-8. doi: 10.1194/jlr.M800427-JLR200. Epub 2009 Jan 14.

23.

Regulation of lipid metabolism by sphingolipids.

Worgall TS.

Subcell Biochem. 2008;49:371-85. doi: 10.1007/978-1-4020-8830-8_14. Review.

PMID:
18751919
24.

Fatty acid supplied as triglyceride regulates SRE-mediated gene expression as efficiently as free fatty acids.

Densupsoontorn N, Worgall TS, Seo T, Hamai H, Deckelbaum RJ.

Lipids. 2007 Oct;42(10):885-91. Epub 2007 Aug 7.

PMID:
17680293
25.

Sphingolipids: major regulators of lipid metabolism.

Worgall TS.

Curr Opin Clin Nutr Metab Care. 2007 Mar;10(2):149-55. Review.

PMID:
17285002
26.

n-3 fatty acids and gene expression.

Deckelbaum RJ, Worgall TS, Seo T.

Am J Clin Nutr. 2006 Jun;83(6 Suppl):1520S-1525S. doi: 10.1093/ajcn/83.6.1520S. Review. Erratum in: Am J Clin Nutr. 2006 Oct;84(4):949.

PMID:
16841862
27.

Saturated fat-rich diet enhances selective uptake of LDL cholesteryl esters in the arterial wall.

Seo T, Qi K, Chang C, Liu Y, Worgall TS, Ramakrishnan R, Deckelbaum RJ.

J Clin Invest. 2005 Aug;115(8):2214-22. Epub 2005 Jul 21.

28.

Ceramide synthesis correlates with the posttranscriptional regulation of the sterol-regulatory element-binding protein.

Worgall TS, Juliano RA, Seo T, Deckelbaum RJ.

Arterioscler Thromb Vasc Biol. 2004 May;24(5):943-8.

PMID:
15132973
29.

Sterol and fatty acid regulatory pathways in a Giardia lamblia-derived promoter: evidence for SREBP as an ancient transcription factor.

Worgall TS, Davis-Hayman SR, Magana MM, Oelkers PM, Zapata F, Juliano RA, Osborne TF, Nash TE, Deckelbaum RJ.

J Lipid Res. 2004 May;45(5):981-8. Epub 2004 Feb 16.

30.
32.

Omega-3 triglycerides modify blood clearance and tissue targeting pathways of lipid emulsions.

Qi K, Seo T, Al-Haideri M, Worgall TS, Vogel T, Carpentier YA, Deckelbaum RJ.

Biochemistry. 2002 Mar 5;41(9):3119-27.

PMID:
11863451
33.

Unsaturated fatty acid-mediated decreases in sterol regulatory element-mediated gene transcription are linked to cellular sphingolipid metabolism.

Worgall TS, Johnson RA, Seo T, Gierens H, Deckelbaum RJ.

J Biol Chem. 2002 Feb 8;277(6):3878-85. Epub 2001 Nov 13.

34.

Differential modulation of ACAT1 and ACAT2 transcription and activity by long chain free fatty acids in cultured cells.

Seo T, Oelkers PM, Giattina MR, Worgall TS, Sturley SL, Deckelbaum RJ.

Biochemistry. 2001 Apr 17;40(15):4756-62.

PMID:
11294643
35.

Unsaturated fatty acids inhibit sterol regulatory element-dependent gene expression: a potential mechanism contributing to hypertriglyceridemia in fat-restricted diets.

Deckelbaum RJ, Johnson RA, Worgall TS.

Proc Soc Exp Biol Med. 2000 Dec;225(3):184-6. Review. No abstract available.

PMID:
11082211
36.

Free cholesterol enhances adenoviral vector gene transfer and expression in CAR-deficient cells.

Worgall S, Worgall TS, Kostarelos K, Singh R, Leopold PL, Hackett NR, Crystal RG.

Mol Ther. 2000 Jan;1(1):39-48.

37.

Lipoprotein lipase-mediated selective uptake from low density lipoprotein requires cell surface proteoglycans and is independent of scavenger receptor class B type 1.

Seo T, Al-Haideri M, Treskova E, Worgall TS, Kako Y, Goldberg IJ, Deckelbaum RJ.

J Biol Chem. 2000 Sep 29;275(39):30355-62.

38.

Fatty acids: links between genes involved in fatty acid and cholesterol metabolism.

Worgall TS, Deckelbaum RJ.

Curr Opin Clin Nutr Metab Care. 1999 Mar;2(2):127-33. Review.

PMID:
10453343
39.

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