Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 37

1.

Inhibition of bile salt transport by drugs associated with liver injury in primary hepatocytes from human, monkey, dog, rat, and mouse.

Zhang J, He K, Cai L, Chen YC, Yang Y, Shi Q, Woolf TF, Ge W, Guo L, Borlak J, Tong W.

Chem Biol Interact. 2016 Aug 5;255:45-54. doi: 10.1016/j.cbi.2016.03.019. Epub 2016 Mar 19.

2.

In vitro model systems to investigate bile salt export pump (BSEP) activity and drug interactions: A review.

Cheng Y, Woolf TF, Gan J, He K.

Chem Biol Interact. 2016 Aug 5;255:23-30. doi: 10.1016/j.cbi.2015.11.029. Epub 2015 Dec 10. Review.

PMID:
26683212
3.

Inhibition of MDR3 Activity in Human Hepatocytes by Drugs Associated with Liver Injury.

He K, Cai L, Shi Q, Liu H, Woolf TF.

Chem Res Toxicol. 2015 Oct 19;28(10):1987-90. doi: 10.1021/acs.chemrestox.5b00201. Epub 2015 Sep 15.

PMID:
26335978
4.

Metabolic activation of troglitazone: identification of a reactive metabolite and mechanisms involved.

He K, Talaat RE, Pool WF, Reily MD, Reed JE, Bridges AJ, Woolf TF.

Drug Metab Dispos. 2004 Jun;32(6):639-46.

PMID:
15155556
5.

Incorporation of an oxygen from water into troglitazone quinone by cytochrome P450 and myeloperoxidase.

He K, Talaat RE, Woolf TF.

Drug Metab Dispos. 2004 Apr;32(4):442-6.

PMID:
15039298
6.

Troglitazone quinone formation catalyzed by human and rat CYP3A: an atypical CYP oxidation reaction.

He K, Woolf TF, Kindt EK, Fielder AE, Talaat RE.

Biochem Pharmacol. 2001 Jul 15;62(2):191-8.

PMID:
11389877
7.

Metabolism and excretion of atorvastatin in rats and dogs.

Black AE, Hayes RN, Roth BD, Woo P, Woolf TF.

Drug Metab Dispos. 1999 Aug;27(8):916-23.

PMID:
10421619
8.

Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486).

He K, Woolf TF, Hollenberg PF.

J Pharmacol Exp Ther. 1999 Feb;288(2):791-7.

PMID:
9918590
9.

Caffeine based measures of CYP1A2 activity correlate with oral clearance of tacrine in patients with Alzheimer's disease.

Fontana RJ, deVries TM, Woolf TF, Knapp MJ, Brown AS, Kaminsky LS, Tang BK, Foster NL, Brown RR, Watkins PB.

Br J Clin Pharmacol. 1998 Sep;46(3):221-8.

10.
11.

Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice.

He K, Iyer KR, Hayes RN, Sinz MW, Woolf TF, Hollenberg PF.

Chem Res Toxicol. 1998 Apr;11(4):252-9.

PMID:
9548795
12.

Characterization of the induction of rat microsomal cytochrome P450 by tacrine.

Sinz MW, Woolf TF.

Biochem Pharmacol. 1997 Aug 1;54(3):425-7.

PMID:
9278102
13.

Metabolic disposition of the cognition activator tacrine in rats, dogs, and humans. Species comparisons.

Pool WF, Reily MD, Bjorge SM, Woolf TF.

Drug Metab Dispos. 1997 May;25(5):590-7.

PMID:
9152598
14.
15.
16.

Identification of a 3-hydroxylated tacrine metabolite in rat and man: metabolic profiling implications and pharmacology.

Pool WF, Woolf TF, Reily MD, Caprathe BW, Emmerling MR, Jaen JC.

J Med Chem. 1996 Jul 19;39(15):3014-8.

PMID:
8709135
17.

Distribution of tacrine and metabolites in rat brain and plasma after single- and multiple-dose regimens. Evidence for accumulation of tacrine in brain tissue.

McNally WP, Pool WF, Sinz MW, Dehart P, Ortwine DF, Huang CC, Chang T, Woolf TF.

Drug Metab Dispos. 1996 Jun;24(6):628-33.

PMID:
8781777
18.

The caffeine breath test does not identify patients susceptible to tacrine hepatotoxicity.

Fontana RJ, Turgeon DK, Woolf TF, Knapp MJ, Foster NL, Watkins PB.

Hepatology. 1996 Jun;23(6):1429-35.

PMID:
8675160
19.

Species variation in the bioactivation of tacrine by hepatic microsomes.

Madden S, Spaldin V, Hayes RN, Woolf TF, Pool WF, Park BK.

Xenobiotica. 1995 Jan;25(1):103-16.

PMID:
7604602
20.
21.

Stereoselective hydroxylation of tacrine in rats and humans.

Hooper WD, Pool WF, Woolf TF, Gal J.

Drug Metab Dispos. 1994 Sep-Oct;22(5):719-24.

PMID:
7835223
22.

The effect of enzyme inhibition on the metabolism and activation of tacrine by human liver microsomes.

Spaldin V, Madden S, Pool WF, Woolf TF, Park BK.

Br J Clin Pharmacol. 1994 Jul;38(1):15-22.

23.

Biodisposition studies with the acyl-coenzyme A: cholesterol acyltransferase inhibitor 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide, CI-976.

Woolf TF, Black A, Shum YY, McNally W, Lee H, Chang T.

Drug Metab Dispos. 1993 Nov-Dec;21(6):1112-8.

PMID:
7905392
24.

Bioactivation and irreversible binding of the cognition activator tacrine using human and rat liver microsomal preparations. Species difference.

Woolf TF, Pool WF, Bjorge SM, Chang T, Goel OP, Purchase CF 2nd, Schroeder MC, Kunze KL, Trager WF.

Drug Metab Dispos. 1993 Sep-Oct;21(5):874-82.

PMID:
7902251
25.
26.

Characterization of nonlinear elimination of the xanthine-related drug ethimizol in 3-methylcholanthrene-induced rat liver by the "parallel-tube" model.

Kukan M, Woolf TF, Melus M, Bezek S.

Drug Metab Dispos. 1993 May-Jun;21(3):547-50. No abstract available.

PMID:
8100515
27.

Metabolic disposition of the non-steroidal anti-inflammatory agent isoxicam in man.

Woolf TF, Black A, Sedman A, Chang T.

Eur J Drug Metab Pharmacokinet. 1992 Jan-Mar;17(1):21-7.

PMID:
1499594
28.
29.

Metabolic disposition of trimetrexate, a nonclassical dihydrofolate reductase inhibitor, in rat and dog.

Wong BK, Woolf TF, Chang T, Whitfield LR.

Drug Metab Dispos. 1990 Nov-Dec;18(6):980-6.

PMID:
1981548
30.

In vitro metabolism of isoxicam by horseradish peroxidase.

Woolf TF, Black A, Chang T.

Xenobiotica. 1989 Dec;19(12):1369-77.

PMID:
2618088
31.

In vivo metabolism of isoxicam in rats, dogs, and monkeys.

Woolf TF, Black A, Hicks JL, Lee H, Huang CC, Chang T.

Drug Metab Dispos. 1989 Nov-Dec;17(6):662-8.

PMID:
2575504
32.
33.

Oxicams: metabolic disposition in man and animals.

Woolf TF, Radulovic LL.

Drug Metab Rev. 1989;21(2):255-76. Review. No abstract available.

PMID:
2517627
35.

Basic concepts in drug metabolism: Part II.

Jordan RA, Woolf TF.

J Clin Pharmacol. 1987 Feb;27(2):87-90. Review.

PMID:
3316305
36.

Basic concepts in drug metabolism: Part I.

Woolf TF, Jordan RA.

J Clin Pharmacol. 1987 Jan;27(1):15-7. Review. No abstract available.

PMID:
3316300
37.

Derivatization of chiral amines with (S,S)-N-trifluoroacetylproline anhydride for GC estimation of enantiomeric composition.

Adams JD Jr, Woolf TF, Trevor AJ, Williams LR, Castagnoli N Jr.

J Pharm Sci. 1982 Jun;71(6):658-61.

PMID:
7097528

Supplemental Content

Loading ...
Support Center