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Items: 40


Uptake of Neisserial autotransporter lipoprotein (NalP) promotes an increase in human brain microvascular endothelial cell metabolic activity.

Dufailu OA, Mahdavi J, Ala'Aldeen DAA, Wooldridge KG, Oldfield NJ.

Microb Pathog. 2018 Nov;124:70-75. doi: 10.1016/j.micpath.2018.08.001. Epub 2018 Aug 4.


Fructose-1,6-bisphosphate aldolase of Neisseria meningitidis binds human plasminogen via its C-terminal lysine residue.

Shams F, Oldfield NJ, Lai SK, Tunio SA, Wooldridge KG, Turner DP.

Microbiologyopen. 2016 Apr;5(2):340-50. doi: 10.1002/mbo3.331. Epub 2016 Jan 5.


Development of a heptaplex PCR assay for identification of Staphylococcus aureus and CoNS with simultaneous detection of virulence and antibiotic resistance genes.

Okolie CE, Wooldridge KG, Turner DP, Cockayne A, James R.

BMC Microbiol. 2015 Aug 5;15:157. doi: 10.1186/s12866-015-0490-9.


Nuclear trafficking, histone cleavage and induction of apoptosis by the meningococcal App and MspA autotransporters.

Khairalla AS, Omer SA, Mahdavi J, Aslam A, Dufailu OA, Self T, Jonsson AB, Geörg M, Sjölinder H, Royer PJ, Martinez-Pomares L, Ghaemmaghami AM, Wooldridge KG, Oldfield NJ, Ala'Aldeen DA.

Cell Microbiol. 2015 Jul;17(7):1008-20. doi: 10.1111/cmi.12417. Epub 2015 Feb 8.


Fructose-1,6-bisphosphate aldolase (FBA)-a conserved glycolytic enzyme with virulence functions in bacteria: 'ill met by moonlight'.

Shams F, Oldfield NJ, Wooldridge KG, Turner DP.

Biochem Soc Trans. 2014 Dec;42(6):1792-5. doi: 10.1042/BST20140203. Review.


Deciphering the complex three-way interaction between the non-integrin laminin receptor, galectin-3 and Neisseria meningitidis.

Alqahtani F, Mahdavi J, Wheldon LM, Vassey M, Pirinccioglu N, Royer PJ, Qarani SM, Morroll S, Stoof J, Holliday ND, Teo SY, Oldfield NJ, Wooldridge KG, Ala'Aldeen DA.

Open Biol. 2014 Oct;4(10). pii: 140053. doi: 10.1098/rsob.140053.


A novel O-linked glycan modulates Campylobacter jejuni major outer membrane protein-mediated adhesion to human histo-blood group antigens and chicken colonization.

Mahdavi J, Pirinccioglu N, Oldfield NJ, Carlsohn E, Stoof J, Aslam A, Self T, Cawthraw SA, Petrovska L, Colborne N, Sihlbom C, Borén T, Wooldridge KG, Ala'Aldeen DA.

Open Biol. 2014 Jan 22;4:130202. doi: 10.1098/rsob.130202.


Deciphering the contribution of human meningothelial cells to the inflammatory and antimicrobial response at the meninges.

Royer PJ, Rogers AJ, Wooldridge KG, Tighe P, Mahdavi J, Rittig MG, Ala'Aldeen D.

Infect Immun. 2013 Nov;81(11):4299-310. doi: 10.1128/IAI.00477-13. Epub 2013 Sep 3.


Mapping the laminin receptor binding domains of Neisseria meningitidis PorA and Haemophilus influenzae OmpP2.

Abouseada NM, Assafi MS, Mahdavi J, Oldfield NJ, Wheldon LM, Wooldridge KG, Ala'Aldeen DA.

PLoS One. 2012;7(9):e46233. doi: 10.1371/journal.pone.0046233. Epub 2012 Sep 25.


Phase variable genes of Campylobacter jejuni exhibit high mutation rates and specific mutational patterns but mutability is not the major determinant of population structure during host colonization.

Bayliss CD, Bidmos FA, Anjum A, Manchev VT, Richards RL, Grossier JP, Wooldridge KG, Ketley JM, Barrow PA, Jones MA, Tretyakov MV.

Nucleic Acids Res. 2012 Jul;40(13):5876-89. doi: 10.1093/nar/gks246. Epub 2012 Mar 20.


Influence of the combination and phase variation status of the haemoglobin receptors HmbR and HpuAB on meningococcal virulence.

Tauseef I, Harrison OB, Wooldridge KG, Feavers IM, Neal KR, Gray SJ, Kriz P, Turner DP, Ala'Aldeen DA, Maiden MC, Bayliss CD.

Microbiology. 2011 May;157(Pt 5):1446-56. doi: 10.1099/mic.0.046946-0. Epub 2011 Feb 10.


The role of glyceraldehyde 3-phosphate dehydrogenase (GapA-1) in Neisseria meningitidis adherence to human cells.

Tunio SA, Oldfield NJ, Ala'Aldeen DA, Wooldridge KG, Turner DP.

BMC Microbiol. 2010 Nov 9;10:280. doi: 10.1186/1471-2180-10-280.


The moonlighting protein fructose-1, 6-bisphosphate aldolase of Neisseria meningitidis: surface localization and role in host cell adhesion.

Tunio SA, Oldfield NJ, Berry A, Ala'Aldeen DA, Wooldridge KG, Turner DP.

Mol Microbiol. 2010 May;76(3):605-15. doi: 10.1111/j.1365-2958.2010.07098.x. Epub 2010 Feb 28.


AasP autotransporter protein of Actinobacillus pleuropneumoniae does not protect pigs against homologous challenge.

Oldfield NJ, Worrall KE, Rycroft AN, Ali T, Wooldridge KG, Ala'Aldeen DA.

Vaccine. 2009 Aug 20;27(38):5278-83. doi: 10.1016/j.vaccine.2009.06.047. Epub 2009 Jun 27.


Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models.

Orihuela CJ, Mahdavi J, Thornton J, Mann B, Wooldridge KG, Abouseada N, Oldfield NJ, Self T, Ala'Aldeen DA, Tuomanen EI.

J Clin Invest. 2009 Jun;119(6):1638-46. doi: 10.1172/JCI36759. Epub 2009 May 11.


Secreted proteins of Neisseria meningitidis protect mice against infection.

Li Y, Wooldridge KG, Javed MA, Tang CM, Ala'aldeen DA.

Vaccine. 2009 Apr 14;27(17):2320-5. doi: 10.1016/j.vaccine.2009.02.034. Epub 2009 Feb 20.


Functional characterization of AasP, a maturation protease autotransporter protein of Actinobacillus pleuropneumoniae.

Ali T, Oldfield NJ, Wooldridge KG, Turner DP, Ala'Aldeen DA.

Infect Immun. 2008 Dec;76(12):5608-14. doi: 10.1128/IAI.00085-08. Epub 2008 Oct 13.


Identification and characterization of novel antigenic vaccine candidates of Actinobacillus pleuropneumoniae.

Oldfield NJ, Donovan EA, Worrall KE, Wooldridge KG, Langford PR, Rycroft AN, Ala'Aldeen DA.

Vaccine. 2008 Apr 7;26(16):1942-54. doi: 10.1016/j.vaccine.2008.02.022. Epub 2008 Feb 27.


Validation of virulence and epidemiology DNA microarray for identification and characterization of Staphylococcus aureus isolates.

Spence RP, Wright V, Ala-Aldeen DA, Turner DP, Wooldridge KG, James R.

J Clin Microbiol. 2008 May;46(5):1620-7. doi: 10.1128/JCM.02453-07. Epub 2008 Feb 20.


CapA, an autotransporter protein of Campylobacter jejuni, mediates association with human epithelial cells and colonization of the chicken gut.

Ashgar SS, Oldfield NJ, Wooldridge KG, Jones MA, Irving GJ, Turner DP, Ala'Aldeen DA.

J Bacteriol. 2007 Mar;189(5):1856-65. Epub 2006 Dec 15.


T-cell stimulating protein A (TspA) of Neisseria meningitidis is required for optimal adhesion to human cells.

Oldfield NJ, Bland SJ, Taraktsoglou M, Dos Ramos FJ, Robinson K, Wooldridge KG, Ala'Aldeen DA.

Cell Microbiol. 2007 Feb;9(2):463-78. Epub 2006 Sep 11.


Characterization of MspA, an immunogenic autotransporter protein that mediates adhesion to epithelial and endothelial cells in Neisseria meningitidis.

Turner DP, Marietou AG, Johnston L, Ho KK, Rogers AJ, Wooldridge KG, Ala'Aldeen DA.

Infect Immun. 2006 May;74(5):2957-64.


Unusual genetic organization of a functional type I protein secretion system in Neisseria meningitidis.

Wooldridge KG, Kizil M, Wells DB, Ala'aldeen DA.

Infect Immun. 2005 Sep;73(9):5554-67.


T-cell-stimulating protein A elicits immune responses during meningococcal carriage and human disease.

Robinson K, Wooldridge KG, Wells DB, Hasan A, Todd I, Robins A, James R, Ala'Aldeen DA.

Infect Immun. 2005 Aug;73(8):4684-93.


Secreted proteins from Neisseria meningitidis mediate differential human gene expression and immune activation.

Robinson K, Taraktsoglou M, Rowe KS, Wooldridge KG, Ala'Aldeen DA.

Cell Microbiol. 2004 Oct;6(10):927-38.


Identification and characterization of App: an immunogenic autotransporter protein of Neisseria meningitidis.

Hadi HA, Wooldridge KG, Robinson K, Ala'Aldeen DA.

Mol Microbiol. 2001 Aug;41(3):611-23.


Auto-transporter A protein of Neisseria meningitidis: a potent CD4+ T-cell and B-cell stimulating antigen detected by expression cloning.

Ait-Tahar K, Wooldridge KG, Turner DP, Atta M, Todd I, Ala'Aldeen DA.

Mol Microbiol. 2000 Sep;37(5):1094-105.


Iron-responsive gene regulation in a campylobacter jejuni fur mutant.

van Vliet AH, Wooldridge KG, Ketley JM.

J Bacteriol. 1998 Oct;180(20):5291-8.


Campylobacter-host cell interactions.

Wooldridge KG, Ketley JM.

Trends Microbiol. 1997 Mar;5(3):96-102. Review.


Host signal transduction and endocytosis of Campylobacter jejuni.

Wooldridge KG, Williams PH, Ketley JM.

Microb Pathog. 1996 Oct;21(4):299-305.


Iron uptake mechanisms of pathogenic bacteria.

Wooldridge KG, Williams PH.

FEMS Microbiol Rev. 1993 Nov;12(4):325-48. Review.


Occurrence of FIme plasmids in multiply antimicrobial-resistant Escherichia coli isolated from urinary tract infection.

Riley PA, Threlfall EJ, Cheasty T, Wooldridge KG, Williams PH, Phillips I.

Epidemiol Infect. 1993 Jun;110(3):459-68.


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