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Items: 31


Cardiovascular disease is obNOXious: New insights into NoxA1 in smooth muscle phenotype.

Orr AW, Woolard MD.

Redox Biol. 2019 Apr;22:101081. doi: 10.1016/j.redox.2018.101081. Epub 2018 Dec 19. No abstract available.


IL-1β reduces cardiac lymphatic muscle contraction via COX-2 and PGE2 induction: Potential role in myocarditis.

Al-Kofahi M, Omura S, Tsunoda I, Sato F, Becker F, Gavins FNE, Woolard MD, Pattillo C, Zawieja D, Muthuchamy M, Gashev A, Shihab I, Ghoweba M, Von der Weid PY, Wang Y, Alexander JS.

Biomed Pharmacother. 2018 Nov;107:1591-1600. doi: 10.1016/j.biopha.2018.08.004. Epub 2018 Sep 6.


AAV8-mediated overexpression of mPCSK9 in liver differs between male and female mice.

Vozenilek AE, Blackburn CMR, Schilke RM, Chandran S, Castore R, Klein RL, Woolard MD.

Atherosclerosis. 2018 Nov;278:66-72. doi: 10.1016/j.atherosclerosis.2018.09.005. Epub 2018 Sep 8.


Gene Transfer Induced Hypercholesterolemia in Amyloid Mice.

Grames MS, Dayton RD, Lu X, Schilke RM, Alexander JS, Orr AW, Barmada SJ, Woolard MD, Klein RL.

J Alzheimers Dis. 2018;65(4):1079-1086. doi: 10.3233/JAD-180494.


Differential arterial and venous endothelial redox responses to oxidative stress.

Shrestha B, Prasai PK, Kaskas AM, Khanna A, Letchuman V, Letchuman S, Alexander JS, Orr AW, Woolard MD, Pattillo CB.

Microcirculation. 2018 Oct;25(7):e12486. doi: 10.1111/micc.12486. Epub 2018 Jul 23.


Absence of Nicotinamide Nucleotide Transhydrogenase in C57BL/6J Mice Exacerbates Experimental Atherosclerosis.

Vozenilek AE, Vetkoetter M, Green JM, Shen X, Traylor JG, Klein RL, Orr AW, Woolard MD, Krzywanski DM.

J Vasc Res. 2018;55(2):98-110. doi: 10.1159/000486337. Epub 2018 Feb 16.


Macrophage-Associated Lipin-1 Enzymatic Activity Contributes to Modified Low-Density Lipoprotein-Induced Proinflammatory Signaling and Atherosclerosis.

Vozenilek AE, Navratil AR, Green JM, Coleman DT, Blackburn CMR, Finney AC, Pearson BH, Chrast R, Finck BN, Klein RL, Orr AW, Woolard MD.

Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):324-334. doi: 10.1161/ATVBAHA.117.310455. Epub 2017 Dec 7. Erratum in: Arterioscler Thromb Vasc Biol. 2018 May;38(5):e89.


EphA2 Expression Regulates Inflammation and Fibroproliferative Remodeling in Atherosclerosis.

Finney AC, Funk SD, Green JM, Yurdagul A Jr, Rana MA, Pistorius R, Henry M, Yurochko A, Pattillo CB, Traylor JG, Chen J, Woolard MD, Kevil CG, Orr AW.

Circulation. 2017 Aug 8;136(6):566-582. doi: 10.1161/CIRCULATIONAHA.116.026644. Epub 2017 May 9.


The arterial microenvironment: the where and why of atherosclerosis.

Yurdagul A Jr, Finney AC, Woolard MD, Orr AW.

Biochem J. 2016 May 15;473(10):1281-95. doi: 10.1042/BJ20150844. Review.


Paying the Toll for Glucose Regulation: A Central Role for TLR3.

Woolard MD, Kevil CG.

Diabetes. 2015 Oct;64(10):3345-6. doi: 10.2337/db15-0679. No abstract available.


Lipin-1 contributes to modified low-density lipoprotein-elicited macrophage pro-inflammatory responses.

Navratil AR, Vozenilek AE, Cardelli JA, Green JM, Thomas MJ, Sorci-Thomas MG, Orr AW, Woolard MD.

Atherosclerosis. 2015 Oct;242(2):424-32. doi: 10.1016/j.atherosclerosis.2015.08.012. Epub 2015 Aug 10.


IL-1β reduces tonic contraction of mesenteric lymphatic muscle cells, with the involvement of cycloxygenase-2 and prostaglandin E2.

Al-Kofahi M, Becker F, Gavins FN, Woolard MD, Tsunoda I, Wang Y, Ostanin D, Zawieja DC, Muthuchamy M, von der Weid PY, Alexander JS.

Br J Pharmacol. 2015 Aug;172(16):4038-51. doi: 10.1111/bph.13194. Epub 2015 Jul 6.


Francisella tularensis LVS induction of prostaglandin biosynthesis by infected macrophages requires specific host phospholipases and lipid phosphatases.

Navratil AR, Brummett AM, Bryan JD, Woolard MD.

Infect Immun. 2014 Aug;82(8):3299-311. doi: 10.1128/IAI.02060-14. Epub 2014 May 27.


Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response.

Barrigan LM, Tuladhar S, Brunton JC, Woolard MD, Chen CJ, Saini D, Frothingham R, Sempowski GD, Kawula TH, Frelinger JA.

Infect Immun. 2013 Jun;81(6):2028-42. doi: 10.1128/IAI.00207-13. Epub 2013 Mar 25.


Identification of Francisella novicida mutants that fail to induce prostaglandin E(2) synthesis by infected macrophages.

Woolard MD, Barrigan LM, Fuller JR, Buntzman AS, Bryan J, Manoil C, Kawula TH, Frelinger JA.

Front Microbiol. 2013 Feb 11;4:16. doi: 10.3389/fmicb.2013.00016. eCollection 2013.


Identification of T-cell epitopes in Francisella tularensis using an ordered protein array of serological targets.

Valentino MD, Maben ZJ, Hensley LL, Woolard MD, Kawula TH, Frelinger JA, Frelinger JG.

Immunology. 2011 Mar;132(3):348-60. doi: 10.1111/j.1365-2567.2010.03387.x. Epub 2011 Jan 7.


NK cells interfere with the generation of resistance against mycoplasma respiratory infection following nasal-pulmonary immunization.

Bodhankar S, Woolard MD, Sun X, Simecka JW.

J Immunol. 2009 Aug 15;183(4):2622-31. doi: 10.4049/jimmunol.0802180. Epub 2009 Jul 22.


Identification of a dominant CD4 T cell epitope in the membrane lipoprotein Tul4 from Francisella tularensis LVS.

Valentino MD, Hensley LL, Skrombolas D, McPherson PL, Woolard MD, Kawula TH, Frelinger JA, Frelinger JG.

Mol Immunol. 2009 May;46(8-9):1830-8. doi: 10.1016/j.molimm.2009.01.008. Epub 2009 Feb 23.


Infected-host-cell repertoire and cellular response in the lung following inhalation of Francisella tularensis Schu S4, LVS, or U112.

Hall JD, Woolard MD, Gunn BM, Craven RR, Taft-Benz S, Frelinger JA, Kawula TH.

Infect Immun. 2008 Dec;76(12):5843-52. doi: 10.1128/IAI.01176-08. Epub 2008 Oct 13.


Outsmarting the host: bacteria modulating the immune response.

Woolard MD, Frelinger JA.

Immunol Res. 2008;41(3):188-202. doi: 10.1007/s12026-008-8021-5.


Respiratory Francisella tularensis live vaccine strain infection induces Th17 cells and prostaglandin E2, which inhibits generation of gamma interferon-positive T cells.

Woolard MD, Hensley LL, Kawula TH, Frelinger JA.

Infect Immun. 2008 Jun;76(6):2651-9. doi: 10.1128/IAI.01412-07. Epub 2008 Apr 7.


Francisella tularensis-infected macrophages release prostaglandin E2 that blocks T cell proliferation and promotes a Th2-like response.

Woolard MD, Wilson JE, Hensley LL, Jania LA, Kawula TH, Drake JR, Frelinger JA.

J Immunol. 2007 Feb 15;178(4):2065-74.


Selective deletion of antigen-specific CD8+ T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein saporin.

Hess PR, Barnes C, Woolard MD, Johnson MD, Cullen JM, Collins EJ, Frelinger JA.

Blood. 2007 Apr 15;109(8):3300-7. Epub 2006 Dec 19.


NK cells in gamma-interferon-deficient mice suppress lung innate immunity against Mycoplasma spp.

Woolard MD, Hudig D, Tabor L, Ivey JA, Simecka JW.

Infect Immun. 2005 Oct;73(10):6742-51.


IL-4-independent pathways exacerbate methacholine-induced airway hyperreactivity during mycoplasma respiratory disease.

Woolard MD, Hardy RD, Simecka JW.

J Allergy Clin Immunol. 2004 Sep;114(3):645-9.


Involvement of protein kinase C-delta in DNA damage-induced apoptosis.

Basu A, Woolard MD, Johnson CL.

Cell Death Differ. 2001 Sep;8(9):899-908.

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