Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 172

1.

A novel anti-malarial drug derivative inhibits cyclic GMP-AMP synthase in Trex1 deficient mice.

An J, Woodward JJ, Lai W, Minie M, Sun X, Tanaka L, Snyder JM, Sasaki T, Elkon KB.

Arthritis Rheumatol. 2018 May 21. doi: 10.1002/art.40559. [Epub ahead of print]

PMID:
29781188
2.

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.

McFarland AP, Burke TP, Carletti AA, Glover RC, Tabakh H, Welch MD, Woodward JJ.

MBio. 2018 May 15;9(3). pii: e00526-18. doi: 10.1128/mBio.00526-18.

3.

Effects of monoamines on the intrinsic excitability of lateral orbitofrontal cortex neurons in alcohol-dependent and non-dependent female mice.

Nimitvilai S, Lopez MF, Woodward JJ.

Neuropharmacology. 2018 Apr 22;137:1-12. doi: 10.1016/j.neuropharm.2018.04.019. [Epub ahead of print]

PMID:
29689260
4.

High-throughput interaction screens illuminate the role of c-di-AMP in cyanobacterial nighttime survival.

Rubin BE, Huynh TN, Welkie DG, Diamond S, Simkovsky R, Pierce EC, Taton A, Lowe LC, Lee JJ, Rifkin SA, Woodward JJ, Golden SS.

PLoS Genet. 2018 Apr 2;14(4):e1007301. doi: 10.1371/journal.pgen.1007301. eCollection 2018 Apr.

5.

Cyclic di-AMP Acts as an Extracellular Signal That Impacts Bacillus subtilis Biofilm Formation and Plant Attachment.

Townsley L, Yannarell SM, Huynh TN, Woodward JJ, Shank EA.

MBio. 2018 Mar 27;9(2). pii: e00341-18. doi: 10.1128/mBio.00341-18.

6.

Effects of drugs of abuse on channelrhodopsin-2 function.

Gioia DA, Xu M, Wayman WN, Woodward JJ.

Neuropharmacology. 2018 Jun;135:316-327. doi: 10.1016/j.neuropharm.2018.03.031. Epub 2018 Mar 23.

PMID:
29580953
7.

Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior.

Cannady R, Rinker JA, Nimitvilai S, Woodward JJ, Mulholland PJ.

Handb Exp Pharmacol. 2018 Jan 28. doi: 10.1007/164_2017_90. [Epub ahead of print]

PMID:
29374839
8.

Loss of Ethanol Inhibition of N-Methyl-D-Aspartate Receptor-Mediated Currents and Plasticity of Cerebellar Synapses in Mice Expressing the GluN1(F639A) Subunit.

Zamudio-Bulcock PA, Homanics GE, Woodward JJ.

Alcohol Clin Exp Res. 2018 Apr;42(4):698-705. doi: 10.1111/acer.13597. Epub 2018 Feb 9.

PMID:
29323417
9.

Chemogenetic Excitation of Accumbens-Projecting Infralimbic Cortical Neurons Blocks Toluene-Induced Conditioned Place Preference.

Wayman WN, Woodward JJ.

J Neurosci. 2018 Feb 7;38(6):1462-1471. doi: 10.1523/JNEUROSCI.2503-17.2018. Epub 2018 Jan 9.

PMID:
29317484
10.

Structural and functional studies of pyruvate carboxylase regulation by cyclic di-AMP in lactic acid bacteria.

Choi PH, Vu TMN, Pham HT, Woodward JJ, Turner MS, Tong L.

Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):E7226-E7235. doi: 10.1073/pnas.1704756114. Epub 2017 Aug 14.

11.

Replication-Transcription Conflicts Generate R-Loops that Orchestrate Bacterial Stress Survival and Pathogenesis.

Lang KS, Hall AN, Merrikh CN, Ragheb M, Tabakh H, Pollock AJ, Woodward JJ, Dreifus JE, Merrikh H.

Cell. 2017 Aug 10;170(4):787-799.e18. doi: 10.1016/j.cell.2017.07.044.

12.

Listeria monocytogenes in Food-Processing Facilities, Food Contamination, and Human Listeriosis: The Brazilian Scenario.

Camargo AC, Woodward JJ, Call DR, Nero LA.

Foodborne Pathog Dis. 2017 Nov;14(11):623-636. doi: 10.1089/fpd.2016.2274. Epub 2017 Aug 2. Review.

PMID:
28767285
13.

Persistent cognitive and morphological alterations induced by repeated exposure of adolescent rats to the abused inhalant toluene.

Braunscheidel KM, Gass JT, Mulholland PJ, Floresco SB, Woodward JJ.

Neurobiol Learn Mem. 2017 Oct;144:136-146. doi: 10.1016/j.nlm.2017.07.007. Epub 2017 Jul 15.

PMID:
28720405
14.

Exposure to the Abused Inhalant Toluene Alters Medial Prefrontal Cortex Physiology.

Wayman WN, Woodward JJ.

Neuropsychopharmacology. 2018 Mar;43(4):912-924. doi: 10.1038/npp.2017.117. Epub 2017 Jun 7.

PMID:
28589963
15.

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

McFarland AP, Luo S, Ahmed-Qadri F, Zuck M, Thayer EF, Goo YA, Hybiske K, Tong L, Woodward JJ.

Immunity. 2017 Mar 21;46(3):433-445. doi: 10.1016/j.immuni.2017.02.014.

16.

Prefrontal Cortex KCa2 Channels Regulate mGlu5-Dependent Plasticity and Extinction of Alcohol-Seeking Behavior.

Cannady R, McGonigal JT, Newsom RJ, Woodward JJ, Mulholland PJ, Gass JT.

J Neurosci. 2017 Apr 19;37(16):4359-4369. doi: 10.1523/JNEUROSCI.2873-16.2017. Epub 2017 Mar 20.

17.

Effects of Repeated Ethanol Exposures on NMDA Receptor Expression and Locomotor Sensitization in Mice Expressing Ethanol Resistant NMDA Receptors.

den Hartog CR, Gilstrap M, Eaton B, Lench DH, Mulholland PJ, Homanics GE, Woodward JJ.

Front Neurosci. 2017 Feb 21;11:84. doi: 10.3389/fnins.2017.00084. eCollection 2017.

18.

Orbitofrontal Neuroadaptations and Cross-Species Synaptic Biomarkers in Heavy-Drinking Macaques.

Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ.

J Neurosci. 2017 Mar 29;37(13):3646-3660. doi: 10.1523/JNEUROSCI.0133-17.2017. Epub 2017 Mar 7.

19.

Ethanol Dependence Abolishes Monoamine and GIRK (Kir3) Channel Inhibition of Orbitofrontal Cortex Excitability.

Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ.

Neuropsychopharmacology. 2017 Aug;42(9):1800-1812. doi: 10.1038/npp.2017.22. Epub 2017 Jan 31.

PMID:
28139680
20.

c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation.

Whiteley AT, Garelis NE, Peterson BN, Choi PH, Tong L, Woodward JJ, Portnoy DA.

Mol Microbiol. 2017 Apr;104(2):212-233. doi: 10.1111/mmi.13622. Epub 2017 Mar 8.

21.

Expression of Cyclic GMP-AMP Synthase in Patients With Systemic Lupus Erythematosus.

An J, Durcan L, Karr RM, Briggs TA, Rice GI, Teal TH, Woodward JJ, Elkon KB.

Arthritis Rheumatol. 2017 Apr;69(4):800-807. doi: 10.1002/art.40002. Epub 2017 Mar 7.

22.

Differential effects of TM4 tryptophan mutations on inhibition of N-methyl-d-aspartate receptors by ethanol and toluene.

Smothers CT, Woodward JJ.

Alcohol. 2016 Nov;56:15-19. doi: 10.1016/j.alcohol.2016.10.001. Epub 2016 Oct 3.

23.

Antimalarial Drugs as Immune Modulators: New Mechanisms for Old Drugs.

An J, Minie M, Sasaki T, Woodward JJ, Elkon KB.

Annu Rev Med. 2017 Jan 14;68:317-330. doi: 10.1146/annurev-med-043015-123453. Epub 2016 Oct 21. Review.

PMID:
27813878
24.

Differential Effects of Toluene and Ethanol on Dopaminergic Neurons of the Ventral Tegmental Area.

Nimitvilai S, You C, Arora DS, McElvain MA, Vandegrift BJ, Brodie MS, Woodward JJ.

Front Neurosci. 2016 Sep 22;10:434. eCollection 2016.

25.

Flying Under the Radar: Immune Evasion by Group B Streptococcus.

McFarland AP, Woodward JJ.

Cell Host Microbe. 2016 Jul 13;20(1):4-6. doi: 10.1016/j.chom.2016.06.015.

26.

Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC.

Huynh TN, Choi PH, Sureka K, Ledvina HE, Campillo J, Tong L, Woodward JJ.

Mol Microbiol. 2016 Oct;102(2):233-243. doi: 10.1111/mmi.13456. Epub 2016 Jul 26.

27.

A novel substituted aminoquinoline selectively targets voltage-sensitive sodium channel isoforms and NMDA receptor subtypes and alleviates chronic inflammatory and neuropathic pain.

Tabakoff B, Ren W, Vanderlinden L, Snell LD, Matheson CJ, Wang ZJ, Levinson R, Smothers CT, Woodward JJ, Honse Y, Lovinger D, Rush AM, Sather WA, Gustafson DL, Hoffman PL.

Eur J Pharmacol. 2016 Aug 5;784:1-14. doi: 10.1016/j.ejphar.2016.05.006. Epub 2016 May 5.

28.

The Continuous Challenge of Characterizing the Foodborne Pathogen Listeria monocytogenes.

Camargo AC, Woodward JJ, Nero LA.

Foodborne Pathog Dis. 2016 Aug;13(8):405-16. doi: 10.1089/fpd.2015.2115. Epub 2016 Apr 27. Review.

PMID:
27120361
29.

Inactivation of the lateral orbitofrontal cortex increases drinking in ethanol-dependent but not non-dependent mice.

den Hartog C, Zamudio-Bulcock P, Nimitvilai S, Gilstrap M, Eaton B, Fedarovich H, Motts A, Woodward JJ.

Neuropharmacology. 2016 Aug;107:451-459. doi: 10.1016/j.neuropharm.2016.03.031. Epub 2016 Mar 23.

30.

Too much of a good thing: regulated depletion of c-di-AMP in the bacterial cytoplasm.

Huynh TN, Woodward JJ.

Curr Opin Microbiol. 2016 Apr;30:22-29. doi: 10.1016/j.mib.2015.12.007. Epub 2016 Jan 7. Review.

31.

Disruption of S2-M4 linker coupling reveals novel subunit-specific contributions to N-methyl-d-aspartate receptor function and ethanol sensitivity.

Hughes BA, Woodward JJ.

Neuropharmacology. 2016 Jun;105:96-105. doi: 10.1016/j.neuropharm.2015.11.009. Epub 2015 Nov 11.

32.

Altered NMDA receptor function in primary cultures of hippocampal neurons from mice lacking the Homer2 gene.

Smothers CT, Szumlinski KK, Worley PF, Woodward JJ.

Synapse. 2016 Jan;70(1):33-9. doi: 10.1002/syn.21869. Epub 2015 Oct 15.

33.

Chronic Intermittent Ethanol Exposure Enhances the Excitability and Synaptic Plasticity of Lateral Orbitofrontal Cortex Neurons and Induces a Tolerance to the Acute Inhibitory Actions of Ethanol.

Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ.

Neuropsychopharmacology. 2016 Mar;41(4):1112-27. doi: 10.1038/npp.2015.250. Epub 2015 Aug 9.

34.

Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome.

Gray EE, Treuting PM, Woodward JJ, Stetson DB.

J Immunol. 2015 Sep 1;195(5):1939-43. doi: 10.4049/jimmunol.1500969. Epub 2015 Jul 29.

35.

STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.

Fu J, Kanne DB, Leong M, Glickman LH, McWhirter SM, Lemmens E, Mechette K, Leong JJ, Lauer P, Liu W, Sivick KE, Zeng Q, Soares KC, Zheng L, Portnoy DA, Woodward JJ, Pardoll DM, Dubensky TW Jr, Kim Y.

Sci Transl Med. 2015 Apr 15;7(283):283ra52. doi: 10.1126/scitranslmed.aaa4306.

36.

Cutting edge: Antimalarial drugs inhibit IFN-β production through blockade of cyclic GMP-AMP synthase-DNA interaction.

An J, Woodward JJ, Sasaki T, Minie M, Elkon KB.

J Immunol. 2015 May 1;194(9):4089-93. doi: 10.4049/jimmunol.1402793. Epub 2015 Mar 27.

37.

Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene.

Beckley JT, Randall PK, Smith RJ, Hughes BA, Kalivas PW, Woodward JJ.

Addict Biol. 2016 May;21(3):530-46. doi: 10.1111/adb.12235. Epub 2015 Mar 6.

38.

Molecular basis for the recognition of cyclic-di-AMP by PstA, a PII-like signal transduction protein.

Choi PH, Sureka K, Woodward JJ, Tong L.

Microbiologyopen. 2015 Jun;4(3):361-74. doi: 10.1002/mbo3.243. Epub 2015 Feb 18.

39.

KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction.

Padula AE, Griffin WC 3rd, Lopez MF, Nimitvilai S, Cannady R, McGuier NS, Chesler EJ, Miles MF, Williams RW, Randall PK, Woodward JJ, Becker HC, Mulholland PJ.

Neuropsychopharmacology. 2015 Jul;40(8):1928-39. doi: 10.1038/npp.2015.42. Epub 2015 Feb 9.

40.

Cysteine substitution of transmembrane domain amino acids alters the ethanol inhibition of GluN1/GluN2A N-methyl-D-aspartate receptors.

Xu M, Smothers CT, Woodward JJ.

J Pharmacol Exp Ther. 2015 Apr;353(1):91-101. doi: 10.1124/jpet.114.222034. Epub 2015 Jan 29.

41.

An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence.

Huynh TN, Luo S, Pensinger D, Sauer JD, Tong L, Woodward JJ.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E747-56. doi: 10.1073/pnas.1416485112. Epub 2015 Jan 12.

42.

Withdrawal from chronic intermittent alcohol exposure increases dendritic spine density in the lateral orbitofrontal cortex of mice.

McGuier NS, Padula AE, Lopez MF, Woodward JJ, Mulholland PJ.

Alcohol. 2015 Feb;49(1):21-7. doi: 10.1016/j.alcohol.2014.07.017. Epub 2014 Nov 3.

43.

Effects of the abused inhalant toluene on the mesolimbic dopamine system.

Woodward JJ, Beckley J.

J Drug Alcohol Res. 2014;3. pii: 235838.

44.

Review of toluene action: clinical evidence, animal studies and molecular targets.

Cruz SL, Rivera-García MT, Woodward JJ.

J Drug Alcohol Res. 2014;3. pii: 235840.

45.

The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function.

Sureka K, Choi PH, Precit M, Delince M, Pensinger DA, Huynh TN, Jurado AR, Goo YA, Sadilek M, Iavarone AT, Sauer JD, Tong L, Woodward JJ.

Cell. 2014 Sep 11;158(6):1389-1401. doi: 10.1016/j.cell.2014.07.046.

46.

Chronic ethanol alters network activity and endocannabinoid signaling in the prefrontal cortex.

Pava MJ, Woodward JJ.

Front Integr Neurosci. 2014 Jul 18;8:58. doi: 10.3389/fnint.2014.00058. eCollection 2014.

47.

Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking.

Mahler SV, Vazey EM, Beckley JT, Keistler CR, McGlinchey EM, Kaufling J, Wilson SP, Deisseroth K, Woodward JJ, Aston-Jones G.

Nat Neurosci. 2014 Apr;17(4):577-85. doi: 10.1038/nn.3664. Epub 2014 Mar 2.

48.

Endocannabinoid modulation of cortical up-states and NREM sleep.

Pava MJ, den Hartog CR, Blanco-Centurion C, Shiromani PJ, Woodward JJ.

PLoS One. 2014 Feb 10;9(2):e88672. doi: 10.1371/journal.pone.0088672. eCollection 2014.

49.

Alterations in ethanol-induced behaviors and consumption in knock-in mice expressing ethanol-resistant NMDA receptors.

den Hartog CR, Beckley JT, Smothers TC, Lench DH, Holseberg ZL, Fedarovich H, Gilstrap MJ, Homanics GE, Woodward JJ.

PLoS One. 2013 Nov 14;8(11):e80541. doi: 10.1371/journal.pone.0080541. eCollection 2013.

50.

Volatile solvents as drugs of abuse: focus on the cortico-mesolimbic circuitry.

Beckley JT, Woodward JJ.

Neuropsychopharmacology. 2013 Dec;38(13):2555-67. doi: 10.1038/npp.2013.206. Epub 2013 Aug 19. Review.

Supplemental Content

Loading ...
Support Center