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Items: 19

1.

Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus.

Buckley MA, Woods NT, Tyrer JP, Mendoza-Fandiño G, Lawrenson K, Hazelett DJ, Najafabadi HS, Gjyshi A, Carvalho RS, Lyra PC Jr, Coetzee SG, Shen HC, Yang AW, Earp MA, Yoder SJ, Risch H, Chenevix-Trench G, Ramus SJ, Phelan CM, Coetzee GA, Noushmehr H, Hughes TR, Sellers TA, Goode EL, Pharoah PD, Gayther SA, Monteiro ANA; Ovarian Cancer Association Consortium.

Cancer Res. 2019 Feb 1;79(3):467-481. doi: 10.1158/0008-5472.CAN-17-3864. Epub 2018 Nov 28.

PMID:
30487138
2.

Germline missense pathogenic variants in the BRCA1 BRCT domain, p.Gly1706Glu and p.Ala1708Glu, increase cellular sensitivity to PARP inhibitor olaparib by a dominant negative effect.

Vaclová T, Woods NT, Megías D, Gomez-Lopez S, Setién F, García Bueno JM, Macías JA, Barroso A, Urioste M, Esteller M, Monteiro ANA, Benítez J, Osorio A.

Hum Mol Genet. 2016 Dec 15;25(24):5287-5299. doi: 10.1093/hmg/ddw343.

3.

PAXIP1 Potentiates the Combination of WEE1 Inhibitor AZD1775 and Platinum Agents in Lung Cancer.

Jhuraney A, Woods NT, Wright G, Rix L, Kinose F, Kroeger JL, Remily-Wood E, Cress WD, Koomen JM, Brantley SG, Gray JE, Haura EB, Rix U, Monteiro AN.

Mol Cancer Ther. 2016 Jul;15(7):1669-81. doi: 10.1158/1535-7163.MCT-15-0182. Epub 2016 May 11.

4.

Functional assays provide a robust tool for the clinical annotation of genetic variants of uncertain significance.

Woods NT, Baskin R, Golubeva V, Jhuraney A, De-Gregoriis G, Vaclova T, Goldgar DE, Couch FJ, Carvalho MA, Iversen ES, Monteiro AN.

NPJ Genom Med. 2016;1. pii: 16001. doi: 10.1038/npjgenmed.2016.1. Epub 2016 Mar 2.

5.

Enhancer scanning to locate regulatory regions in genomic loci.

Buckley M, Gjyshi A, Mendoza-Fandiño G, Baskin R, Carvalho RS, Carvalho MA, Woods NT, Monteiro AN.

Nat Protoc. 2016 Jan;11(1):46-60. doi: 10.1038/nprot.2015.136. Epub 2015 Dec 10.

6.

Functional analysis of the 11q23.3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility.

Baskin R, Woods NT, Mendoza-Fandiño G, Forsyth P, Egan KM, Monteiro AN.

Sci Rep. 2015 Nov 27;5:17367. doi: 10.1038/srep17367.

7.

Interleukin polymorphisms associated with overall survival, disease-free survival, and recurrence in non-small cell lung cancer patients.

Woods NT, Monteiro AN, Thompson ZJ, Amankwah EK, Naas N, Haura EB, Beg AA, Schabath MB.

Mol Carcinog. 2015 Jun;54 Suppl 1:E172-84. doi: 10.1002/mc.22275. Epub 2015 Jan 18.

8.

Incorporating computational resources in a cancer research program.

Woods NT, Jhuraney A, Monteiro AN.

Hum Genet. 2015 May;134(5):467-78. doi: 10.1007/s00439-014-1496-3. Epub 2014 Oct 17. Review.

9.

Characterization of LGALS3 (galectin-3) as a player in DNA damage response.

Carvalho RS, Fernandes VC, Nepomuceno TC, Rodrigues DC, Woods NT, Suarez-Kurtz G, Chammas R, Monteiro AN, Carvalho MA.

Cancer Biol Ther. 2014 Jul;15(7):840-50. doi: 10.4161/cbt.28873. Epub 2014 Apr 22.

10.

Localization of BRCA1 protein in breast cancer tissue and cell lines with mutations.

Tulchin N, Ornstein L, Dikman S, Strauchen J, Jaffer S, Nagi C, Bleiweiss I, Kornreich R, Edelmann L, Brown K, Bodian C, Nair VD, Chambon M, Woods NT, Monteiro AN.

Cancer Cell Int. 2013 Jul 15;13(1):70. doi: 10.1186/1475-2867-13-70.

11.

Charting the landscape of tandem BRCT domain-mediated protein interactions.

Woods NT, Mesquita RD, Sweet M, Carvalho MA, Li X, Liu Y, Nguyen H, Thomas CE, Iversen ES Jr, Marsillac S, Karchin R, Koomen J, Monteiro AN.

Sci Signal. 2012 Sep 18;5(242):rs6.

12.

BRCT domains: A little more than kin, and less than kind.

Gerloff DL, Woods NT, Farago AA, Monteiro AN.

FEBS Lett. 2012 Aug 14;586(17):2711-6. doi: 10.1016/j.febslet.2012.05.005. Epub 2012 May 11. Review.

13.

Yeast two-hybrid junk sequences contain selected linear motifs.

Liu Y, Woods NT, Kim D, Sweet M, Monteiro AN, Karchin R.

Nucleic Acids Res. 2011 Oct;39(19):e128. doi: 10.1093/nar/gkr600. Epub 2011 Jul 23.

14.

Tandem BRCT Domains: DNA's Praetorian Guard.

Mesquita RD, Woods NT, Seabra-Junior ES, Monteiro AN.

Genes Cancer. 2010 Nov;1(11):1140-6. doi: 10.1177/1947601910392988.

15.

BRCA1 protein and nucleolin colocalize in breast carcinoma tissue and cancer cell lines.

Tulchin N, Chambon M, Juan G, Dikman S, Strauchen J, Ornstein L, Billack B, Woods NT, Monteiro AN.

Am J Pathol. 2010 Mar;176(3):1203-14. doi: 10.2353/ajpath.2010.081063. Epub 2010 Jan 14.

16.

p53 acetylation is crucial for its transcription-independent proapoptotic functions.

Yamaguchi H, Woods NT, Piluso LG, Lee HH, Chen J, Bhalla KN, Monteiro A, Liu X, Hung MC, Wang HG.

J Biol Chem. 2009 Apr 24;284(17):11171-83. doi: 10.1074/jbc.M809268200. Epub 2009 Mar 5.

17.

SRC directly phosphorylates Bif-1 and prevents its interaction with Bax and the initiation of anoikis.

Yamaguchi H, Woods NT, Dorsey JF, Takahashi Y, Gjertsen NR, Yeatman T, Wu J, Wang HG.

J Biol Chem. 2008 Jul 4;283(27):19112-8. doi: 10.1074/jbc.M709882200. Epub 2008 May 12.

18.

Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis.

Woods NT, Yamaguchi H, Lee FY, Bhalla KN, Wang HG.

Cancer Res. 2007 Nov 15;67(22):10744-52.

19.

Shp2E76K mutant confers cytokine-independent survival of TF-1 myeloid cells by up-regulating Bcl-XL.

Ren Y, Chen Z, Chen L, Woods NT, Reuther GW, Cheng JQ, Wang HG, Wu J.

J Biol Chem. 2007 Dec 14;282(50):36463-73. Epub 2007 Oct 17.

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