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Items: 25


Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.

Bakowski MA, Shiroodi RK, Liu R, Olejniczak J, Yang B, Gagaring K, Guo H, White PM, Chappell L, Debec A, Landmann F, Dubben B, Lenz F, Struever D, Ehrens A, Frohberger SJ, Sjoberg H, Pionnier N, Murphy E, Archer J, Steven A, Chunda VC, Fombad FF, Chounna PW, Njouendou AJ, Metuge HM, Ndzeshang BL, Gandjui NV, Akumtoh DN, Kwenti TDB, Woods AK, Joseph SB, Hull MV, Xiong W, Kuhen KL, Taylor MJ, Wanji S, Turner JD, Hübner MP, Hoerauf A, Chatterjee AK, Roland J, Tremblay MS, Schultz PG, Sullivan W, Chu XJ, Petrassi HM, McNamara CW.

Sci Transl Med. 2019 May 8;11(491). pii: eaav3523. doi: 10.1126/scitranslmed.aav3523.


Switchable control over in vivo CAR T expansion, B cell depletion, and induction of memory.

Viaud S, Ma JSY, Hardy IR, Hampton EN, Benish B, Sherwood L, Nunez V, Ackerman CJ, Khialeeva E, Weglarz M, Lee SC, Woods AK, Young TS.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10898-E10906. doi: 10.1073/pnas.1810060115. Epub 2018 Oct 29.


The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis.

Janes J, Young ME, Chen E, Rogers NH, Burgstaller-Muehlbacher S, Hughes LD, Love MS, Hull MV, Kuhen KL, Woods AK, Joseph SB, Petrassi HM, McNamara CW, Tremblay MS, Su AI, Schultz PG, Chatterjee AK.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10750-10755. doi: 10.1073/pnas.1810137115. Epub 2018 Oct 3.


Dynamic shear analysis: a novel method to determine mechanical integrity of normal and torn human acetabular labra: Implications for prediction of outcome of repair.

Woods AK, Broomfield J, Monk P, Vollrath F, Glyn-Jones S.

Bone Joint Res. 2018 Aug 4;7(7):440-446. doi: 10.1302/2046-3758.77.BJR-2017-0282.R2. eCollection 2018 Jul.


A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open-Access Malaria Box.

Jumani RS, Bessoff K, Love MS, Miller P, Stebbins EE, Teixeira JE, Campbell MA, Meyers MJ, Zambriski JA, Nunez V, Woods AK, McNamara CW, Huston CD.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e01505-17. doi: 10.1128/AAC.01505-17. Print 2018 Apr.


Development of A Chimeric Antigen Receptor Targeting C-Type Lectin-Like Molecule-1 for Human Acute Myeloid Leukemia.

Laborda E, Mazagova M, Shao S, Wang X, Quirino H, Woods AK, Hampton EN, Rodgers DT, Kim CH, Schultz PG, Young TS.

Int J Mol Sci. 2017 Oct 27;18(11). pii: E2259. doi: 10.3390/ijms18112259.


Ex Vivo Cell-Based Screening Platform for Modulators of Hepatosteatosis.

Yu S, Chen E, Sherwood L, Hull M, Woods AK, Tremblay MS.

ACS Chem Biol. 2017 Jul 21;12(7):1937-1946. doi: 10.1021/acschembio.7b00420. Epub 2017 Jun 16.


Small molecule selectively suppresses MYC transcription in cancer cells.

Bouvard C, Lim SM, Ludka J, Yazdani N, Woods AK, Chatterjee AK, Schultz PG, Zhu S.

Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3497-3502. doi: 10.1073/pnas.1702663114. Epub 2017 Mar 14.


Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells via an Antibody-drug Conjugate.

Yu S, Pearson AD, Lim RK, Rodgers DT, Li S, Parker HB, Weglarz M, Hampton EN, Bollong MJ, Shen J, Zambaldo C, Wang D, Woods AK, Wright TM, Schultz PG, Kazane SA, Young TS, Tremblay MS.

Mol Ther. 2016 Dec;24(12):2078-2089. doi: 10.1038/mt.2016.175. Epub 2016 Oct 12.


Decidual Cox2 inhibition improves fetal and maternal outcomes in a preeclampsia-like mouse model.

Sones JL, Cha J, Woods AK, Bartos A, Heyward CY, Lob HE, Isroff CE, Butler SD, Shapiro SE, Dey SK, Davisson RL.

JCI Insight. 2016 Mar 17;1(3). pii: 75351. doi: 10.1172/jci.insight.75351.


Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery.

Yang PY, Zou H, Chao E, Sherwood L, Nunez V, Keeney M, Ghartey-Tagoe E, Ding Z, Quirino H, Luo X, Welzel G, Chen G, Singh P, Woods AK, Schultz PG, Shen W.

Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):4140-5. doi: 10.1073/pnas.1601653113. Epub 2016 Mar 28.


Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies.

Rodgers DT, Mazagova M, Hampton EN, Cao Y, Ramadoss NS, Hardy IR, Schulman A, Du J, Wang F, Singer O, Ma J, Nunez V, Shen J, Woods AK, Wright TM, Schultz PG, Kim CH, Young TS.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):E459-68. doi: 10.1073/pnas.1524155113. Epub 2016 Jan 12.


Design of Potent and Proteolytically Stable Oxyntomodulin Analogs.

Muppidi A, Zou H, Yang PY, Chao E, Sherwood L, Nunez V, Woods AK, Schultz PG, Lin Q, Shen W.

ACS Chem Biol. 2016 Feb 19;11(2):324-8. doi: 10.1021/acschembio.5b00787. Epub 2016 Jan 4.


A Small Molecule Inhibits Deregulated NRF2 Transcriptional Activity in Cancer.

Bollong MJ, Yun H, Sherwood L, Woods AK, Lairson LL, Schultz PG.

ACS Chem Biol. 2015 Oct 16;10(10):2193-8. doi: 10.1021/acschembio.5b00448. Epub 2015 Aug 17.


Histological and mechanical differences in the skin of patients with rectal prolapse.

Joshi HM, Woods AK, Smyth E, Gosselink MP, Cunningham C, Lindsey I, Urban J, Jones OM, Vollrath F.

Int J Colorectal Dis. 2015 Aug;30(8):1117-22. doi: 10.1007/s00384-015-2222-x. Epub 2015 Apr 29.


Distal-less 3 haploinsufficiency results in elevated placental oxidative stress and altered fetal growth kinetics in the mouse.

Clark PA, Brown JL, Li S, Woods AK, Han L, Sones JL, Preston RL, Southard TL, Davisson RL, Roberson MS.

Placenta. 2012 Oct;33(10):830-8. doi: 10.1016/j.placenta.2012.06.018. Epub 2012 Jul 19.


Adenoviral delivery of VEGF121 early in pregnancy prevents spontaneous development of preeclampsia in BPH/5 mice.

Woods AK, Hoffmann DS, Weydert CJ, Butler SD, Zhou Y, Sharma RV, Davisson RL.

Hypertension. 2011 Jan;57(1):94-102. doi: 10.1161/HYPERTENSIONAHA.110.160242. Epub 2010 Nov 15.


Impact of body weight on performance of a weight-supported motor fitness test in men.

Bishop PA, Crowder TA, Fielitz LR, Lindsay TR, Woods AK.

Mil Med. 2008 Nov;173(11):1108-14.


Cross-sectional area and muscular strength: a brief review.

Jones EJ, Bishop PA, Woods AK, Green JM.

Sports Med. 2008;38(12):987-94. doi: 10.2165/00007256-200838120-00003. Review.


Recovery from training: a brief review: brief review.

Bishop PA, Jones E, Woods AK.

J Strength Cond Res. 2008 May;22(3):1015-24. doi: 10.1519/JSC.0b013e31816eb518. Review.


Cytosolic phospholipase A2 regulation in the hibernating thirteen-lined ground squirrel.

Woods AK, Storey KB.

Cell Mol Biol Lett. 2007;12(4):621-32. Epub 2007 Aug 30.


African Americans and their distrust of the health care system: healthcare for diverse populations.

Kennedy BR, Mathis CC, Woods AK.

J Cult Divers. 2007 Summer;14(2):56-60. Review.


Vertebrate freezing survival: Regulation of the multicatalytic proteinase complex and controls on protein degradation.

Woods AK, Storey KB.

Biochim Biophys Acta. 2006 Mar;1760(3):395-403. Epub 2006 Jan 11.


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