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Items: 20

1.

Parkinson's Disease: Mitochondria Parked at the ER Hit the Snooze Button.

Woodling NS, Partridge L.

Neuron. 2018 Jun 27;98(6):1059-1061. doi: 10.1016/j.neuron.2018.06.025.

PMID:
29953866
2.

G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.

Simone R, Balendra R, Moens TG, Preza E, Wilson KM, Heslegrave A, Woodling NS, Niccoli T, Gilbert-Jaramillo J, Abdelkarim S, Clayton EL, Clarke M, Konrad MT, Nicoll AJ, Mitchell JS, Calvo A, Chio A, Houlden H, Polke JM, Ismail MA, Stephens CE, Vo T, Farahat AA, Wilson WD, Boykin DW, Zetterberg H, Partridge L, Wray S, Parkinson G, Neidle S, Patani R, Fratta P, Isaacs AM.

EMBO Mol Med. 2018 Jan;10(1):22-31. doi: 10.15252/emmm.201707850.

3.

Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration.

Mizielinska S, Ridler CE, Balendra R, Thoeng A, Woodling NS, Grässer FA, Plagnol V, Lashley T, Partridge L, Isaacs AM.

Acta Neuropathol Commun. 2017 Apr 18;5(1):29. doi: 10.1186/s40478-017-0432-x.

4.

Deficiency in Neuronal TGF-β Signaling Leads to Nigrostriatal Degeneration and Activation of TGF-β Signaling Protects against MPTP Neurotoxicity in Mice.

Tesseur I, Nguyen A, Chang B, Li L, Woodling NS, Wyss-Coray T, Luo J.

J Neurosci. 2017 Apr 26;37(17):4584-4592. doi: 10.1523/JNEUROSCI.2952-16.2017. Epub 2017 Mar 31.

5.

A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin.

Kinghorn KJ, Grönke S, Castillo-Quan JI, Woodling NS, Li L, Sirka E, Gegg M, Mills K, Hardy J, Bjedov I, Partridge L.

J Neurosci. 2016 Nov 16;36(46):11654-11670.

6.

Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice.

Woodling NS, Colas D, Wang Q, Minhas P, Panchal M, Liang X, Mhatre SD, Brown H, Ko N, Zagol-Ikapitte I, van der Hart M, Khroyan TV, Chuluun B, Priyam PG, Milne GL, Rassoulpour A, Boutaud O, Manning-Boğ AB, Heller HC, Andreasson KI.

Brain. 2016 Jul;139(Pt 7):2063-81. doi: 10.1093/brain/aww117. Epub 2016 May 13.

7.

Untangling the Web: Toxic and Protective Effects of Neuroinflammation and PGE2 Signaling in Alzheimer's Disease.

Woodling NS, Andreasson KI.

ACS Chem Neurosci. 2016 Apr 20;7(4):454-63. doi: 10.1021/acschemneuro.6b00016. Epub 2016 Apr 4. Review.

8.
9.

Inflammatory Cyclooxygenase Activity and PGE2 Signaling in Models of Alzheimer's Disease.

Johansson JU, Woodling NS, Shi J, Andreasson KI.

Curr Immunol Rev. 2015 Aug;11(2):125-131. doi: 10.2174/1573395511666150707181414.

10.

Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models.

Johansson JU, Woodling NS, Wang Q, Panchal M, Liang X, Trueba-Saiz A, Brown HD, Mhatre SD, Loui T, Andreasson KI.

J Clin Invest. 2015 Jan;125(1):350-64. doi: 10.1172/JCI77487. Epub 2014 Dec 8.

11.

Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.

Woodling NS, Wang Q, Priyam PG, Larkin P, Shi J, Johansson JU, Zagol-Ikapitte I, Boutaud O, Andreasson KI.

J Neurosci. 2014 Apr 23;34(17):5882-94. doi: 10.1523/JNEUROSCI.0410-14.2014.

12.

Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia.

Johansson JU, Pradhan S, Lokteva LA, Woodling NS, Ko N, Brown HD, Wang Q, Loh C, Cekanaviciute E, Buckwalter M, Manning-Bog AB, Andreasson KI.

J Neurosci. 2013 Oct 2;33(40):16016-32. doi: 10.1523/JNEUROSCI.2203-13.2013.

13.

Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease.

Shi J, Wang Q, Johansson JU, Liang X, Woodling NS, Priyam P, Loui TM, Merchant M, Breyer RM, Montine TJ, Andreasson K.

Ann Neurol. 2012 Nov;72(5):788-98. doi: 10.1002/ana.23677. Epub 2012 Aug 22.

14.

Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis.

Grant JL, Ghosn EE, Axtell RC, Herges K, Kuipers HF, Woodling NS, Andreasson K, Herzenberg LA, Herzenberg LA, Steinman L.

Sci Transl Med. 2012 Aug 1;4(145):145ra105. doi: 10.1126/scitranslmed.3004145.

15.

Signaling via the prostaglandin E₂ receptor EP4 exerts neuronal and vascular protection in a mouse model of cerebral ischemia.

Liang X, Lin L, Woodling NS, Wang Q, Anacker C, Pan T, Merchant M, Andreasson K.

J Clin Invest. 2011 Nov;121(11):4362-71. doi: 10.1172/JCI46279. Epub 2011 Oct 3.

16.

Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold.

Grabrucker AM, Schmeisser MJ, Udvardi PT, Arons M, Schoen M, Woodling NS, Andreasson KI, Hof PR, Buxbaum JD, Garner CC, Boeckers TM.

Mol Neurodegener. 2011 Sep 22;6:65. doi: 10.1186/1750-1326-6-65.

17.

The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity.

Shi J, Johansson J, Woodling NS, Wang Q, Montine TJ, Andreasson K.

J Immunol. 2010 Jun 15;184(12):7207-18. doi: 10.4049/jimmunol.0903487. Epub 2010 May 7.

18.

Insertional inactivation of the L13a ribosomal protein gene of Drosophila melanogaster identifies a new Minute locus.

Alexander SJ, Woodling NS, Yedvobnick B.

Gene. 2006 Mar 1;368:46-52. Epub 2005 Dec 2.

PMID:
16326033
19.

The role of histone acetylation in SMN gene expression.

Kernochan LE, Russo ML, Woodling NS, Huynh TN, Avila AM, Fischbeck KH, Sumner CJ.

Hum Mol Genet. 2005 May 1;14(9):1171-82. Epub 2005 Mar 16.

PMID:
15772088
20.

An EP overexpression screen for genetic modifiers of Notch pathway function in Drosophila melanogaster.

Hall LE, Alexander SJ, Chang M, Woodling NS, Yedvobnick B.

Genet Res. 2004 Apr;83(2):71-82.

PMID:
15219152

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