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Items: 1 to 50 of 424

1.

Stably high azithromycin resistance and decreasing ceftriaxone susceptibility in Neisseria gonorrhoeae in 25 European countries, 2016.

Day MJ, Spiteri G, Jacobsson S, Woodford N, Amato-Gauci AJ, Cole MJ, Unemo M; Euro-GASP network.

BMC Infect Dis. 2018 Dec 3;18(1):609. doi: 10.1186/s12879-018-3528-4.

2.

Factors that impact on the burden of Escherichia coli bacteraemia: multivariable regression analysis of 2011-2015 data from West London.

Blandy O, Honeyford K, Gharbi M, Thomas A, Ramzan F, Ellington MJ, Hope R, Holmes AH, Johnson AP, Aylin P, Woodford N, Sriskandan S.

J Hosp Infect. 2018 Nov 4. pii: S0195-6701(18)30585-1. doi: 10.1016/j.jhin.2018.10.024. [Epub ahead of print]

PMID:
30403958
3.

OXA-1 β-lactamase and non-susceptibility to penicillin/β-lactamase inhibitor combinations among ESBL-producing Escherichia coli.

Livermore DM, Day M, Cleary P, Hopkins KL, Toleman MA, Wareham DW, Wiuff C, Doumith M, Woodford N.

J Antimicrob Chemother. 2018 Nov 2. doi: 10.1093/jac/dky453. [Epub ahead of print]

PMID:
30388219
4.

Developmental roadmap for antimicrobial susceptibility testing systems.

van Belkum A, Bachmann TT, Lüdke G, Lisby JG, Kahlmeter G, Mohess A, Becker K, Hays JP, Woodford N, Mitsakakis K, Moran-Gilad J, Vila J, Peter H, Rex JH, Dunne WM Jr; JPIAMR AMR-RDT Working Group on Antimicrobial Resistance and Rapid Diagnostic Testing.

Nat Rev Microbiol. 2018 Oct 17. doi: 10.1038/s41579-018-0098-9. [Epub ahead of print] Review.

PMID:
30333569
5.

A Large, Refractory Nosocomial Outbreak of Klebsiella pneumoniae Carbapenemase-Producing Escherichia coli Demonstrates Carbapenemase Gene Outbreaks Involving Sink Sites Require Novel Approaches to Infection Control.

Decraene V, Phan HTT, George R, Wyllie DH, Akinremi O, Aiken Z, Cleary P, Dodgson A, Pankhurst L, Crook DW, Lenney C, Walker AS, Woodford N, Sebra R, Fath-Ordoubadi F, Mathers AJ, Seale AC, Guiver M, McEwan A, Watts V, Welfare W, Stoesser N, Cawthorne J; TRACE Investigators’ Group .

Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e01689-18. doi: 10.1128/AAC.01689-18. Print 2018 Dec.

PMID:
30249685
6.

Selection of mutants with resistance or diminished susceptibility to ceftazidime/avibactam from ESBL- and AmpC-producing Enterobacteriaceae.

Livermore DM, Mushtaq S, Doumith M, Jamrozy D, Nichols WW, Woodford N.

J Antimicrob Chemother. 2018 Dec 1;73(12):3336-3345. doi: 10.1093/jac/dky363.

PMID:
30247546
7.
8.

Evaluation of the NG-Test CARBA 5 multiplex immunochromatographic assay for the detection of KPC, OXA-48-like, NDM, VIM and IMP carbapenemases.

Hopkins KL, Meunier D, Naas T, Volland H, Woodford N.

J Antimicrob Chemother. 2018 Dec 1;73(12):3523-3526. doi: 10.1093/jac/dky342. No abstract available.

PMID:
30189008
9.

Global spread of three multidrug-resistant lineages of Staphylococcus epidermidis.

Lee JYH, Monk IR, Gonçalves da Silva A, Seemann T, Chua KYL, Kearns A, Hill R, Woodford N, Bartels MD, Strommenger B, Laurent F, Dodémont M, Deplano A, Patel R, Larsen AR, Korman TM, Stinear TP, Howden BP.

Nat Microbiol. 2018 Oct;3(10):1175-1185. doi: 10.1038/s41564-018-0230-7. Epub 2018 Sep 3.

PMID:
30177740
10.

Defining the architecture of KPC-2 Carbapenemase: identifying allosteric networks to fight antibiotics resistance.

Galdadas I, Lovera S, Pérez-Hernández G, Barnes MD, Healy J, Afsharikho H, Woodford N, Bonomo RA, Gervasio FL, Haider S.

Sci Rep. 2018 Aug 27;8(1):12916. doi: 10.1038/s41598-018-31176-0.

11.

The role of whole genome sequencing in monitoring antimicrobial resistance: A biosafety and public health priority in the Arabian Peninsula.

Alghoribi MF, Balkhy HH, Woodford N, Ellington MJ.

J Infect Public Health. 2018 Nov - Dec;11(6):784-787. doi: 10.1016/j.jiph.2018.08.001. Epub 2018 Aug 9.

12.

Survey of screening methods, rates and policies for the detection of carbapenemase-producing Enterobacteriaceae in English hospitals.

Berry C, Davies K, Woodford N, Wilcox M, Chilton C.

J Hosp Infect. 2018 Aug 7. pii: S0195-6701(18)30416-X. doi: 10.1016/j.jhin.2018.08.005. [Epub ahead of print]

PMID:
30092291
13.

Escherichia coli Sequence Type 410 Is Causing New International High-Risk Clones.

Roer L, Overballe-Petersen S, Hansen F, Schønning K, Wang M, Røder BL, Hansen DS, Justesen US, Andersen LP, Fulgsang-Damgaard D, Hopkins KL, Woodford N, Falgenhauer L, Chakraborty T, Samuelsen Ø, Sjöström K, Johannesen TB, Ng K, Nielsen J, Ethelberg S, Stegger M, Hammerum AM, Hasman H.

mSphere. 2018 Jul 18;3(4). pii: e00337-18. doi: 10.1128/mSphere.00337-18.

14.

Activity of RX-04 Pyrrolocytosine Protein Synthesis Inhibitors against Multidrug-Resistant Gram-Negative Bacteria.

Vickers A, Mushtaq S, Woodford N, Doumith M, Livermore DM.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00689-18. doi: 10.1128/AAC.00689-18. Print 2018 Aug.

PMID:
29914946
15.

Transfer of a gonococcal β-lactamase plasmid into Neisseria gonorrhoeae belonging to the globally distributed ST1407 lineage.

Cole MJ, Ison C, Woodford N.

J Antimicrob Chemother. 2018 Sep 1;73(9):2576-2577. doi: 10.1093/jac/dky194. No abstract available.

PMID:
29868925
16.

Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of Klebsiella pneumoniae Carbapenemase-Carrying Plasmids.

Buckner MMC, Saw HTH, Osagie RN, McNally A, Ricci V, Wand ME, Woodford N, Ivens A, Webber MA, Piddock LJV.

MBio. 2018 Apr 24;9(2). pii: e02303-17. doi: 10.1128/mBio.02303-17.

17.

Author Correction: Rapid susceptibility profiling of carbapenem-resistant Klebsiella pneumoniae.

Mulroney KT, Hall JM, Huang X, Turnbull E, Bzdyl NM, Chakera A, Naseer U, Corea EM, Ellington MJ, Hopkins KL, Wester AL, Ekelund O, Woodford N, Inglis TJJ.

Sci Rep. 2018 Apr 24;8(1):6697. doi: 10.1038/s41598-018-25216-y.

18.

Characterization of Carbapenemase-Producing Enterobacteriaceae from Patients in Amman, Jordan.

Aqel AA, Findlay J, Al-Maayteh M, Al-Kaabneh A, Hopkins KL, Alzoubi H, Masalha I, Turton J, Woodford N, Ellington MJ.

Microb Drug Resist. 2018 Oct;24(8):1121-1127. doi: 10.1089/mdr.2017.0238. Epub 2018 Mar 8.

PMID:
29653473
19.

Prediction of Phenotypic Antimicrobial Resistance Profiles From Whole Genome Sequences of Non-typhoidal Salmonella enterica.

Neuert S, Nair S, Day MR, Doumith M, Ashton PM, Mellor KC, Jenkins C, Hopkins KL, Woodford N, de Pinna E, Godbole G, Dallman TJ.

Front Microbiol. 2018 Mar 27;9:592. doi: 10.3389/fmicb.2018.00592. eCollection 2018.

20.

High prevalence of 16S rRNA methyltransferases among carbapenemase-producing Enterobacteriaceae in the UK and Ireland.

Taylor E, Sriskandan S, Woodford N, Hopkins KL.

Int J Antimicrob Agents. 2018 Aug;52(2):278-282. doi: 10.1016/j.ijantimicag.2018.03.016. Epub 2018 Mar 27.

PMID:
29596903
21.

Cysteamine, an Endogenous Aminothiol, and Cystamine, the Disulfide Product of Oxidation, Increase Pseudomonas aeruginosa Sensitivity to Reactive Oxygen and Nitrogen Species and Potentiate Therapeutic Antibiotics against Bacterial Infection.

Fraser-Pitt DJ, Mercer DK, Smith D, Kowalczuk A, Robertson J, Lovie E, Perenyi P, Cole M, Doumith M, Hill RLR, Hopkins KL, Woodford N, O'Neil DA.

Infect Immun. 2018 May 22;86(6). pii: e00947-17. doi: 10.1128/IAI.00947-17. Print 2018 Jun.

22.

Pseudomonas aeruginosa sequence type 357 with VEB extended-spectrum β-lactamases in the UK: relatedness and resistance.

Greenwood B, Meunier D, Hopkins KL, Pike R, Ivanov Z, Turton JF, Hill R, Woodford N, Livermore DM.

Int J Antimicrob Agents. 2018 Aug;52(2):301-302. doi: 10.1016/j.ijantimicag.2018.03.013. Epub 2018 Mar 23. No abstract available.

PMID:
29580931
23.

Sustained transmission of high-level azithromycin-resistant Neisseria gonorrhoeae in England: an observational study.

Fifer H, Cole M, Hughes G, Padfield S, Smolarchuk C, Woodford N, Wensley A, Mustafa N, Schaefer U, Myers R, Templeton K, Shepherd J, Underwood A.

Lancet Infect Dis. 2018 May;18(5):573-581. doi: 10.1016/S1473-3099(18)30122-1. Epub 2018 Mar 6.

PMID:
29523496
24.

Prevalence of carbapenem resistance and carbapenemase production among Enterobacteriaceae isolated from urine in the UK: results of the UK infection-Carbapenem Resistance Evaluation Surveillance Trial (iCREST-UK).

Woodford N, Xu-McCrae L, Mushtaq S, Wu HHT, Ellington MJ, Lancaster O, Davies F, Donaldson H, Rao GG, Verma A, Wareham DW, Ciesielczuk H, Stone GG, Irani PM, Bracher S, Hawkey PM.

J Antimicrob Chemother. 2017 Dec 15. doi: 10.1093/jac/dkx471. [Epub ahead of print]

PMID:
29253163
25.

Activity of ceftazidime/avibactam against problem Enterobacteriaceae and Pseudomonas aeruginosa in the UK, 2015-16.

Livermore DM, Meunier D, Hopkins KL, Doumith M, Hill R, Pike R, Staves P, Woodford N.

J Antimicrob Chemother. 2017 Dec 8. doi: 10.1093/jac/dkx438. [Epub ahead of print]

PMID:
29228202
26.

Major haemorrhage fatalities in the Australian national coronial database.

Gipson JS, Wood EM, Cole-Sinclair MF, McQuilten Z, Waters N, Woodford NW.

Emerg Med Australas. 2018 Jun;30(3):382-388. doi: 10.1111/1742-6723.12915. Epub 2017 Dec 10.

PMID:
29224237
27.

Comparison of phenotypic and WGS-derived antimicrobial resistance profiles of Salmonella enterica serovars Typhi and Paratyphi.

Day MR, Doumith M, Do Nascimento V, Nair S, Ashton PM, Jenkins C, Dallman TJ, Stevens FJ, Freedman J, Hopkins KL, Woodford N, De Pinna EM, Godbole G.

J Antimicrob Chemother. 2018 Feb 1;73(2):365-372. doi: 10.1093/jac/dkx379.

PMID:
29216342
28.

Phenotypic antimicrobial susceptibility testing of Chlamydia trachomatis isolates from patients with persistent or successfully treated infections.

Pitt R, Alexander S, Ison C, Horner P, Hathorn E, Goold P, Woodford N, Cole MJ.

J Antimicrob Chemother. 2017 Nov 30. doi: 10.1093/jac/dkx454. [Epub ahead of print]

PMID:
29207004
29.

Virulence genes in isolates of Klebsiella pneumoniae from the UK during 2016, including among carbapenemase gene-positive hypervirulent K1-ST23 and 'non-hypervirulent' types ST147, ST15 and ST383.

Turton JF, Payne Z, Coward A, Hopkins KL, Turton JA, Doumith M, Woodford N.

J Med Microbiol. 2018 Jan;67(1):118-128. doi: 10.1099/jmm.0.000653. Epub 2017 Dec 5.

PMID:
29205138
30.

rpoB gene sequencing highlights the prevalence of an E. miricola cluster over other Elizabethkingia species among UK cystic fibrosis patients.

Kenna DTD, Fuller A, Martin K, Perry C, Pike R, Burns PJ, Narayan O, Wilkinson S, Hill R, Woodford N, Logan JMJ, Turton JF.

Diagn Microbiol Infect Dis. 2018 Feb;90(2):109-114. doi: 10.1016/j.diagmicrobio.2017.10.014. Epub 2017 Oct 26.

PMID:
29174734
31.

Molecular and epidemiological characterization of carbapenemase-producing Enterobacteriaceae in Norway, 2007 to 2014.

Samuelsen Ø, Overballe-Petersen S, Bjørnholt JV, Brisse S, Doumith M, Woodford N, Hopkins KL, Aasnæs B, Haldorsen B, Sundsfjord A; Norwegian Study Group on CPE.

PLoS One. 2017 Nov 15;12(11):e0187832. doi: 10.1371/journal.pone.0187832. eCollection 2017.

32.

Evaluation of the Mycoplasma genitalium Resistance Plus kit for the detection of M. genitalium and mutations associated with macrolide resistance.

Pitt R, Cole MJ, Fifer H, Woodford N.

Sex Transm Infect. 2018 Dec;94(8):565-567. doi: 10.1136/sextrans-2017-053366. Epub 2017 Nov 3.

PMID:
29101246
33.

Genomic sequences of Streptococcus agalactiae with high-level gentamicin resistance, collected in the BSAC bacteraemia surveillance.

Doumith M, Mushtaq S, Martin V, Chaudhry A, Adkin R, Coelho J, Chalker V, MacGowan A, Woodford N, Livermore DM; BSAC Resistance Surveillance Standing Committee.

J Antimicrob Chemother. 2017 Oct 1;72(10):2704-2707. doi: 10.1093/jac/dkx207.

PMID:
29091185
34.

Potential of high-dose cefepime/tazobactam against multiresistant Gram-negative pathogens.

Livermore DM, Mushtaq S, Warner M, Turner SJ, Woodford N.

J Antimicrob Chemother. 2018 Jan 1;73(1):126-133. doi: 10.1093/jac/dkx360.

PMID:
29059308
35.

Sharing of carbapenemase-encoding plasmids between Enterobacteriaceae in UK sewage uncovered by MinION sequencing.

Ludden C, Reuter S, Judge K, Gouliouris T, Blane B, Coll F, Naydenova P, Hunt M, Tracey A, Hopkins KL, Brown NM, Woodford N, Parkhill J, Peacock SJ.

Microb Genom. 2017 Jul 4;3(7):e000114. doi: 10.1099/mgen.0.000114. eCollection 2017 Jul.

36.

Emergence and clonal spread of colistin resistance due to multiple mutational mechanisms in carbapenemase-producing Klebsiella pneumoniae in London.

Otter JA, Doumith M, Davies F, Mookerjee S, Dyakova E, Gilchrist M, Brannigan ET, Bamford K, Galletly T, Donaldson H, Aanensen DM, Ellington MJ, Hill R, Turton JF, Hopkins KL, Woodford N, Holmes A.

Sci Rep. 2017 Oct 5;7(1):12711. doi: 10.1038/s41598-017-12637-4.

37.

AmpC β-lactamase induction by avibactam and relebactam.

Livermore DM, Jamrozy D, Mushtaq S, Nichols WW, Young K, Woodford N.

J Antimicrob Chemother. 2017 Dec 1;72(12):3342-3348. doi: 10.1093/jac/dkx298.

PMID:
28962008
38.

Comparison of phenotypic and WGS-derived antimicrobial resistance profiles of enteroaggregative Escherichia coli isolated from cases of diarrhoeal disease in England, 2015-16.

Do Nascimento V, Day MR, Doumith M, Hopkins KL, Woodford N, Godbole G, Jenkins C.

J Antimicrob Chemother. 2017 Dec 1;72(12):3288-3297. doi: 10.1093/jac/dkx301.

PMID:
28961934
39.

Covert dissemination of carbapenemase-producing Klebsiella pneumoniae (KPC) in a successfully controlled outbreak: long- and short-read whole-genome sequencing demonstrate multiple genetic modes of transmission.

Martin J, Phan HTT, Findlay J, Stoesser N, Pankhurst L, Navickaite I, De Maio N, Eyre DW, Toogood G, Orsi NM, Kirby A, Young N, Turton JF, Hill RLR, Hopkins KL, Woodford N, Peto TEA, Walker AS, Crook DW, Wilcox MH.

J Antimicrob Chemother. 2017 Nov 1;72(11):3025-3034. doi: 10.1093/jac/dkx264.

40.

Overall Low Extended-Spectrum Cephalosporin Resistance but high Azithromycin Resistance in Neisseria gonorrhoeae in 24 European Countries, 2015.

Cole MJ, Spiteri G, Jacobsson S, Woodford N, Tripodo F, Amato-Gauci AJ, Unemo M; Euro-GASP network.

BMC Infect Dis. 2017 Sep 11;17(1):617. doi: 10.1186/s12879-017-2707-z.

41.

Multicentre evaluation of the BYG Carba v2.0 test, a simplified electrochemical assay for the rapid laboratory detection of carbapenemase-producing Enterobacteriaceae.

Bogaerts P, Oueslati S, Meunier D, Nonhoff C, Yunus S, Massart M, Denis O, Woodford N, Hopkins KL, Naas T, Dortet L, Huang TD, Glupczynski Y.

Sci Rep. 2017 Aug 30;7(1):9937. doi: 10.1038/s41598-017-09820-y.

42.

Can post-mortem CT and angiography provide all the answers?

O'Donnell C, Lynch M, Woodford N.

Lancet. 2017 Aug 12;390(10095):646-647. doi: 10.1016/S0140-6736(17)31828-7. No abstract available.

PMID:
28816131
43.

Ralstonia infection in cystic fibrosis.

Green HD, Bright-Thomas R, Kenna DT, Turton JF, Woodford N, Jones AM.

Epidemiol Infect. 2017 Oct;145(13):2864-2872. doi: 10.1017/S0950268817001728. Epub 2017 Aug 9.

PMID:
28791938
44.

Diversity, virulence, and antimicrobial resistance of the KPC-producing Klebsiella pneumoniae ST307 clone.

Villa L, Feudi C, Fortini D, Brisse S, Passet V, Bonura C, Endimiani A, Mammina C, Ocampo AM, Jimenez JN, Doumith M, Woodford N, Hopkins K, Carattoli A.

Microb Genom. 2017 Apr 26;3(4):e000110. doi: 10.1099/mgen.0.000110. eCollection 2017 Apr.

45.

Detection of markers predictive of macrolide and fluoroquinolone resistance in Mycoplasma genitalium from patients attending sexual health services in England.

Pitt R, Fifer H, Woodford N, Alexander S.

Sex Transm Infect. 2018 Feb;94(1):9-13. doi: 10.1136/sextrans-2017-053164. Epub 2017 Jul 17.

PMID:
28717051
46.

First outbreak of colonization by linezolid- and glycopeptide-resistant Enterococcus faecium harbouring the cfr gene in a UK nephrology unit.

Inkster T, Coia J, Meunier D, Doumith M, Martin K, Pike R, Imrie L, Kane H, Hay M, Wiuff C, Wilson J, Deighan C, Hopkins KL, Woodford N, Hill R.

J Hosp Infect. 2017 Dec;97(4):397-402. doi: 10.1016/j.jhin.2017.07.003. Epub 2017 Jul 8.

PMID:
28698020
47.

Analysis of the potential for point-of-care test to enable individualised treatment of infections caused by antimicrobial-resistant and susceptible strains of Neisseria gonorrhoeae: a modelling study.

Turner KM, Christensen H, Adams EJ, McAdams D, Fifer H, McDonnell A, Woodford N.

BMJ Open. 2017 Jun 14;7(6):e015447. doi: 10.1136/bmjopen-2016-015447.

48.

FRI-2 carbapenemase-producing Enterobacter cloacae complex in the UK.

Meunier D, Findlay J, Doumith M, Godoy D, Perry C, Pike R, Gronthoud F, Shryane T, Poirel L, Welfare W, Woodford N, Hopkins KL.

J Antimicrob Chemother. 2017 Sep 1;72(9):2478-2482. doi: 10.1093/jac/dkx173.

PMID:
28605515
49.

Comparison of phenotypic and WGS-derived antimicrobial resistance profiles of Shigella sonnei isolated from cases of diarrhoeal disease in England and Wales, 2015.

Sadouki Z, Day MR, Doumith M, Chattaway MA, Dallman TJ, Hopkins KL, Elson R, Woodford N, Godbole G, Jenkins C.

J Antimicrob Chemother. 2017 Sep 1;72(9):2496-2502. doi: 10.1093/jac/dkx170.

PMID:
28591819
50.

The effect of post-mortem computed tomography angiography (PMCTA) using water-soluble, iodine-based radiographic contrast on histological analysis of the liver, kidneys and left ventricle of the heart.

Higgins S, Parsons S, Woodford N, Lynch M, Briggs C, O'Donnell C.

Forensic Sci Med Pathol. 2017 Sep;13(3):317-327. doi: 10.1007/s12024-017-9871-8. Epub 2017 May 20.

PMID:
28526950

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