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Items: 32


A high-throughput method to identify trans-activation domains within transcription factor sequences.

Arnold CD, Nemčko F, Woodfin AR, Wienerroither S, Vlasova A, Schleiffer A, Pagani M, Rath M, Stark A.

EMBO J. 2018 Jul 13. pii: e98896. doi: 10.15252/embj.201798896. [Epub ahead of print]


Solid, Cystic, and Tubular: Novice Ultrasound Skills Training Using a Versatile, Affordable Practice Model.

Sevak S, Lurvey B, Woodfin AA, Hothem Z, Callahan RE, Robbins J, Ziegler K.

J Surg Educ. 2018 Apr 9. pii: S1931-7204(17)30548-2. doi: 10.1016/j.jsurg.2018.02.010. [Epub ahead of print]


Gelatin Thoracic Paravertebral Teaching Model for Placement of a Continuous Infusion Catheter in the Extrathoracic Paravertebral Space.

Sevak S, Woodfin A, Hothem Z, Callahan R, Robbins J, Ziegler K.

J Surg Educ. 2018 Feb 9. pii: S1931-7204(17)30571-8. doi: 10.1016/j.jsurg.2018.01.009. [Epub ahead of print]


Resolving systematic errors in widely used enhancer activity assays in human cells.

Muerdter F, Boryń ŁM, Woodfin AR, Neumayr C, Rath M, Zabidi MA, Pagani M, Haberle V, Kazmar T, Catarino RR, Schernhuber K, Arnold CD, Stark A.

Nat Methods. 2018 Feb;15(2):141-149. doi: 10.1038/nmeth.4534. Epub 2017 Dec 11.


Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas.

Piunti A, Hashizume R, Morgan MA, Bartom ET, Horbinski CM, Marshall SA, Rendleman EJ, Ma Q, Takahashi YH, Woodfin AR, Misharin AV, Abshiru NA, Lulla RR, Saratsis AM, Kelleher NL, James CD, Shilatifard A.

Nat Med. 2017 Apr;23(4):493-500. doi: 10.1038/nm.4296. Epub 2017 Feb 27.


Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.

Liang K, Volk AG, Haug JS, Marshall SA, Woodfin AR, Bartom ET, Gilmore JM, Florens L, Washburn MP, Sullivan KD, Espinosa JM, Cannova J, Zhang J, Smith ER, Crispino JD, Shilatifard A.

Cell. 2017 Jan 12;168(1-2):59-72.e13. doi: 10.1016/j.cell.2016.12.011. Epub 2017 Jan 5.


Underlying chronic inflammation alters the profile and mechanisms of acute neutrophil recruitment.

Ma B, Whiteford JR, Nourshargh S, Woodfin A.

J Pathol. 2016 Nov;240(3):291-303. doi: 10.1002/path.4776.


Mutually Supportive Mechanisms of Inflammation and Vascular Remodeling.

Whiteford JR, De Rossi G, Woodfin A.

Int Rev Cell Mol Biol. 2016;326:201-78. doi: 10.1016/bs.ircmb.2016.05.001. Epub 2016 Jun 27. Review.


An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements Implemented by Trx/MLL/COMPASS.

Rickels R, Hu D, Collings CK, Woodfin AR, Piunti A, Mohan M, Herz HM, Kvon E, Shilatifard A.

Mol Cell. 2016 Jul 21;63(2):318-328. doi: 10.1016/j.molcel.2016.06.018.


TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers.

Morton PE, Hicks A, Ortiz-Zapater E, Raghavan S, Pike R, Noble A, Woodfin A, Jenkins G, Rayner E, Santis G, Parsons M.

Sci Rep. 2016 May 19;6:26321. doi: 10.1038/srep26321.


F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling.

Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, van Unen J, Pitter B, Huveneers S, Goedhart J, Wu Y, Montanez E, Woodfin A, van Buul JD.

Nat Commun. 2016 Jan 27;7:10493. doi: 10.1038/ncomms10493.


Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity.

Luo Z, Lin C, Woodfin AR, Bartom ET, Gao X, Smith ER, Shilatifard A.

Genes Dev. 2016 Jan 1;30(1):92-101. doi: 10.1101/gad.270413.115.


ICAM-1-expressing neutrophils exhibit enhanced effector functions in murine models of endotoxemia.

Woodfin A, Beyrau M, Voisin MB, Ma B, Whiteford JR, Hordijk PL, Hogg N, Nourshargh S.

Blood. 2016 Feb 18;127(7):898-907. doi: 10.1182/blood-2015-08-664995. Epub 2015 Dec 8.


Mitotic Transcriptional Activation: Clearance of Actively Engaged Pol II via Transcriptional Elongation Control in Mitosis.

Liang K, Woodfin AR, Slaughter BD, Unruh JR, Box AC, Rickels RA, Gao X, Haug JS, Jaspersen SL, Shilatifard A.

Mol Cell. 2015 Nov 5;60(3):435-45. doi: 10.1016/j.molcel.2015.09.021.


PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II.

Chen FX, Woodfin AR, Gardini A, Rickels RA, Marshall SA, Smith ER, Shiekhattar R, Shilatifard A.

Cell. 2015 Aug 27;162(5):1003-15. doi: 10.1016/j.cell.2015.07.042. Epub 2015 Aug 13.


Sexual dimorphisms in leukocyte trafficking in a mouse peritonitis model.

Kay E, Gomez-Garcia L, Woodfin A, Scotland RS, Whiteford JR.

J Leukoc Biol. 2015 Nov;98(5):805-17. doi: 10.1189/jlb.3A1214-601RR. Epub 2015 Jul 2.


Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo.

Colom B, Bodkin JV, Beyrau M, Woodfin A, Ody C, Rourke C, Chavakis T, Brohi K, Imhof BA, Nourshargh S.

Immunity. 2015 Jun 16;42(6):1075-86. doi: 10.1016/j.immuni.2015.05.010. Epub 2015 Jun 2.


Shed syndecan-2 inhibits angiogenesis.

De Rossi G, Evans AR, Kay E, Woodfin A, McKay TR, Nourshargh S, Whiteford JR.

J Cell Sci. 2014 Nov 1;127(Pt 21):4788-99. doi: 10.1242/jcs.153015.


Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation.

Thornton JL, Westfield GH, Takahashi YH, Cook M, Gao X, Woodfin AR, Lee JS, Morgan MA, Jackson J, Smith ER, Couture JF, Skiniotis G, Shilatifard A.

Genes Dev. 2014 Jan 15;28(2):115-20. doi: 10.1101/gad.232215.113. Epub 2014 Jan 8.


ICAM-2 facilitates luminal interactions between neutrophils and endothelial cells in vivo.

Halai K, Whiteford J, Ma B, Nourshargh S, Woodfin A.

J Cell Sci. 2014 Feb 1;127(Pt 3):620-9. doi: 10.1242/jcs.137463. Epub 2013 Dec 6.


Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis.

Alazawi W, Heath H, Waters JA, Woodfin A, O'Brien AJ, Scarzello AJ, Ma B, Lopez-Otalora Y, Jacobs M, Petts G, Goldin RD, Nourshargh S, Gamero AM, Foster GR.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8656-61. doi: 10.1073/pnas.1221652110. Epub 2013 May 7.


Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.

Proebstl D, Voisin MB, Woodfin A, Whiteford J, D'Acquisto F, Jones GE, Rowe D, Nourshargh S.

J Exp Med. 2012 Jun 4;209(6):1219-34. doi: 10.1084/jem.20111622. Epub 2012 May 21.


Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves.

Colom B, Poitelon Y, Huang W, Woodfin A, Averill S, Del Carro U, Zambroni D, Brain SD, Perretti M, Ahluwalia A, Priestley JV, Chavakis T, Imhof BA, Feltri ML, Nourshargh S.

FASEB J. 2012 Mar;26(3):1064-76. doi: 10.1096/fj.11-196220. Epub 2011 Nov 16.


The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo.

Woodfin A, Voisin MB, Beyrau M, Colom B, Caille D, Diapouli FM, Nash GB, Chavakis T, Albelda SM, Rainger GE, Meda P, Imhof BA, Nourshargh S.

Nat Immunol. 2011 Jun 26;12(8):761-9. doi: 10.1038/ni.2062.


Acute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia-reperfusion.

Woodfin A, Hu DE, Sarker M, Kurokawa T, Fraser P.

Free Radic Biol Med. 2011 Feb 15;50(4):518-24. doi: 10.1016/j.freeradbiomed.2010.12.010. Epub 2010 Dec 16.


Recent developments and complexities in neutrophil transmigration.

Woodfin A, Voisin MB, Nourshargh S.

Curr Opin Hematol. 2010 Jan;17(1):9-17. doi: 10.1097/MOH.0b013e3283333930. Review.


Junctional adhesion molecule-C mediates leukocyte infiltration in response to ischemia reperfusion injury.

Scheiermann C, Colom B, Meda P, Patel NS, Voisin MB, Marrelli A, Woodfin A, Pitzalis C, Thiemermann C, Aurrand-Lions M, Imhof BA, Nourshargh S.

Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1509-15. doi: 10.1161/ATVBAHA.109.187559. Epub 2009 Jul 2.


Monocytes and neutrophils exhibit both distinct and common mechanisms in penetrating the vascular basement membrane in vivo.

Voisin MB, Woodfin A, Nourshargh S.

Arterioscler Thromb Vasc Biol. 2009 Aug;29(8):1193-9. doi: 10.1161/ATVBAHA.109.187450. Epub 2009 Jun 4.


Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1.

Woodfin A, Voisin MB, Imhof BA, Dejana E, Engelhardt B, Nourshargh S.

Blood. 2009 Jun 11;113(24):6246-57. doi: 10.1182/blood-2008-11-188375. Epub 2009 Feb 10.


PECAM-1: a multi-functional molecule in inflammation and vascular biology.

Woodfin A, Voisin MB, Nourshargh S.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2514-23. Epub 2007 Sep 13. Review.


JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration.

Woodfin A, Reichel CA, Khandoga A, Corada M, Voisin MB, Scheiermann C, Haskard DO, Dejana E, Krombach F, Nourshargh S.

Blood. 2007 Sep 15;110(6):1848-56. Epub 2007 May 15.


ICAM-2 mediates neutrophil transmigration in vivo: evidence for stimulus specificity and a role in PECAM-1-independent transmigration.

Huang MT, Larbi KY, Scheiermann C, Woodfin A, Gerwin N, Haskard DO, Nourshargh S.

Blood. 2006 Jun 15;107(12):4721-7. Epub 2006 Feb 9.

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