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A Million Crystal Structures: The Whole Is Greater than the Sum of Its Parts.

Taylor R, Wood PA.

Chem Rev. 2019 Aug 28;119(16):9427-9477. doi: 10.1021/acs.chemrev.9b00155. Epub 2019 Jun 17.


Tisagenlecleucel Model-Based Cellular Kinetic Analysis of Chimeric Antigen Receptor-T Cells.

Stein AM, Grupp SA, Levine JE, Laetsch TW, Pulsipher MA, Boyer MW, August KJ, Levine BL, Tomassian L, Shah S, Leung M, Huang PH, Awasthi R, Mueller KT, Wood PA, June CH.

CPT Pharmacometrics Syst Pharmacol. 2019 May;8(5):285-295. doi: 10.1002/psp4.12388. Epub 2019 Mar 7.


Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia.

Orlando EJ, Han X, Tribouley C, Wood PA, Leary RJ, Riester M, Levine JE, Qayed M, Grupp SA, Boyer M, De Moerloose B, Nemecek ER, Bittencourt H, Hiramatsu H, Buechner J, Davies SM, Verneris MR, Nguyen K, Brogdon JL, Bitter H, Morrissey M, Pierog P, Pantano S, Engelman JA, Winckler W.

Nat Med. 2018 Oct;24(10):1504-1506. doi: 10.1038/s41591-018-0146-z. Epub 2018 Oct 1.


Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia.

Mueller KT, Waldron E, Grupp SA, Levine JE, Laetsch TW, Pulsipher MA, Boyer MW, August KJ, Hamilton J, Awasthi R, Stein AM, Sickert D, Chakraborty A, Levine BL, June CH, Tomassian L, Shah SS, Leung M, Taran T, Wood PA, Maude SL.

Clin Cancer Res. 2018 Dec 15;24(24):6175-6184. doi: 10.1158/1078-0432.CCR-18-0758. Epub 2018 Sep 6.


Correction to: Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel.

Porter D, Frey N, Wood PA, Weng Y, Grupp SA.

J Hematol Oncol. 2018 Jun 13;11(1):81. doi: 10.1186/s13045-018-0627-z.


False-positive results with select HIV-1 NAT methods following lentivirus-based tisagenlecleucel therapy.

Laetsch TW, Maude SL, Milone MC, Davis KL, Krueger J, Cardenas AM, Eldjerou LK, Keir CH, Wood PA, Grupp SA.

Blood. 2018 Jun 7;131(23):2596-2598. doi: 10.1182/blood-2017-12-822940. Epub 2018 Apr 18. No abstract available.


Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel.

Porter D, Frey N, Wood PA, Weng Y, Grupp SA.

J Hematol Oncol. 2018 Mar 2;11(1):35. doi: 10.1186/s13045-018-0571-y. Review. Erratum in: J Hematol Oncol. 2018 Jun 13;11(1):81.


Use of the PIXEL method to investigate gas adsorption in metal-organic frameworks.

Maloney AGP, Wood PA, Parsons S.

CrystEngComm. 2016 May 14;18(18):3273-3281. doi: 10.1039/c6ce00555a. Epub 2016 Apr 20.


Capturing neon - the first experimental structure of neon trapped within a metal-organic environment.

Wood PA, Sarjeant AA, Yakovenko AA, Ward SC, Groom CR.

Chem Commun (Camb). 2016 Aug 21;52(65):10048-51. doi: 10.1039/c6cc04808k. Epub 2016 Jul 25.


Mental Health Service Use in Schools and Non-School-Based Outpatient Settings: Comparing Predictors of Service Use.

Langer DA, Wood JJ, Wood PA, Garland AF, Landsverk J, Hough RL.

School Ment Health. 2015 Sep 1;7(3):161-173. Epub 2015 Mar 4.


Carnitine Palmitoyltransferase 1b Deficient Mice Develop Severe Insulin Resistance After Prolonged High Fat Diet Feeding.

Kim T, Moore JF, Sharer JD, Yang K, Wood PA, Yang Q.

J Diabetes Metab. 2014;5. pii: 1000401.


Carnitine Palmitoyltransferase 1b Deficiency Protects Mice from Diet-Induced Insulin Resistance.

Kim T, He L, Johnson MS, Li Y, Zeng L, Ding Y, Long Q, Moore JF, Sharer JD, Nagy TR, Young ME, Wood PA, Yang Q.

J Diabetes Metab. 2014 Apr 1;5(4):361.


Hydrogen-bond coordination in organic crystal structures: statistics, predictions and applications.

Galek PT, Chisholm JA, Pidcock E, Wood PA.

Acta Crystallogr B Struct Sci Cryst Eng Mater. 2014 Feb;70(Pt 1):91-105. doi: 10.1107/S2052520613033003. Epub 2014 Jan 16.


Hydrogen-bond landscapes, geometry and energetics of squaric acid and its mono- and dianions: a Cambridge Structural Database, IsoStar and computational study.

Allen FH, Cruz-Cabeza AJ, Wood PA, Bardwell DA.

Acta Crystallogr B Struct Sci Cryst Eng Mater. 2013 Oct;69(Pt 5):514-23. doi: 10.1107/S2052519213020277. Epub 2013 Sep 13.


Role of chloroform and dichloromethane solvent molecules in crystal packing: an interaction propensity study.

Allen FH, Wood PA, Galek PT.

Acta Crystallogr B Struct Sci Cryst Eng Mater. 2013 Aug;69(Pt 4):379-88. doi: 10.1107/S2052519213015078. Epub 2013 Jul 18.


Genomic structure and genetic drift in C57BL/6 congenic metabolic mutant mice.

Almodovar AJ, Luther RJ, Stonebrook CL, Wood PA.

Mol Genet Metab. 2013 Nov;110(3):396-400. doi: 10.1016/j.ymgme.2013.06.019. Epub 2013 Jul 2.


The versatile role of the ethynyl group in crystal packing: an interaction propensity study.

Allen FH, Wood PA, Galek PT.

Acta Crystallogr B Struct Sci Cryst Eng Mater. 2013 Jun;69(Pt 3):281-7. doi: 10.1107/S2052519213008208. Epub 2013 May 8.


Carnitine palmitoyltransferase-1b deficiency aggravates pressure overload-induced cardiac hypertrophy caused by lipotoxicity.

He L, Kim T, Long Q, Liu J, Wang P, Zhou Y, Ding Y, Prasain J, Wood PA, Yang Q.

Circulation. 2012 Oct 2;126(14):1705-16. doi: 10.1161/CIRCULATIONAHA.111.075978. Epub 2012 Aug 29.


New software for statistical analysis of Cambridge Structural Database data.

Sykes RA, McCabe P, Allen FH, Battle GM, Bruno IJ, Wood PA.

J Appl Crystallogr. 2011 Aug 1;44(Pt 4):882-886. Epub 2011 Jun 8.


Acadl-SNP based genotyping assay for long-chain acyl-CoA dehydrogenase deficient mice.

Luther RJ, Almodovar AJ, Fullerton R, Wood PA.

Mol Genet Metab. 2012 May;106(1):62-7. doi: 10.1016/j.ymgme.2012.02.009. Epub 2012 Feb 15.


The hydrogen bond environments of 1H-tetrazole and tetrazolate rings: the structural basis for tetrazole-carboxylic acid bioisosterism.

Allen FH, Groom CR, Liebeschuetz JW, Bardwell DA, Olsson TS, Wood PA.

J Chem Inf Model. 2012 Mar 26;52(3):857-66. doi: 10.1021/ci200521k. Epub 2012 Feb 21.


School attendance problems and youth psychopathology: structural cross-lagged regression models in three longitudinal data sets.

Wood JJ, Lynne-Landsman SD, Langer DA, Wood PA, Clark SL, Eddy JM, Ialongo N.

Child Dev. 2012 Jan-Feb;83(1):351-66. doi: 10.1111/j.1467-8624.2011.01677.x. Epub 2011 Dec 21.


The association of quality of life with potentially remediable disruptions of circadian sleep/activity rhythms in patients with advanced lung cancer.

Grutsch JF, Ferrans C, Wood PA, Du-Quiton J, Quiton DF, Reynolds JL, Ansell CM, Oh EY, Daehler MA, Levin RD, Braun DP, Gupta D, Lis CG, Hrushesky WJ.

BMC Cancer. 2011 May 23;11:193. doi: 10.1186/1471-2407-11-193.


Validation of actigraphy to assess circadian organization and sleep quality in patients with advanced lung cancer.

Grutsch JF, Wood PA, Du-Quiton J, Reynolds JL, Lis CG, Levin RD, Ann Daehler M, Gupta D, Quiton DF, Hrushesky WJ.

J Circadian Rhythms. 2011 May 18;9:4. doi: 10.1186/1740-3391-9-4.


Using the outer coordination sphere to tune the strength of metal extractants.

Forgan RS, Roach BD, Wood PA, White FJ, Campbell J, Henderson DK, Kamenetzky E, McAllister FE, Parsons S, Pidcock E, Richardson P, Swart RM, Tasker PA.

Inorg Chem. 2011 May 16;50(10):4515-22. doi: 10.1021/ic200154y. Epub 2011 Apr 21.


A pilot study of male breast cancer in the Veterans Affairs healthcare system.

Satram-Hoang S, Moran EM, Anton-Culver H, Burras RW, Heimann TM, Boggio I, Dykstra-Long GR, Wood PA, Zulka R, Hufnagel G, Bahan KK.

J Environ Pathol Toxicol Oncol. 2010;29(3):235-44.


Circadian transcription profile of mouse breast cancer under light-dark and dark-dark conditions.

Oh EY, Yang X, Friedman A, Ansell CM, Du-Quiton J, Quiton DF, Wood PA, Hrushesky WJ.

Cancer Genomics Proteomics. 2010 Nov-Dec;7(6):311-22.


Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase.

Chumanevich AA, Poudyal D, Cui X, Davis T, Wood PA, Smith CD, Hofseth LJ.

Carcinogenesis. 2010 Oct;31(10):1787-93. doi: 10.1093/carcin/bgq158. Epub 2010 Aug 5.


Mitochondrial fatty acid oxidation disorders: pathophysiological studies in mouse models.

Spiekerkoetter U, Wood PA.

J Inherit Metab Dis. 2010 Oct;33(5):539-46. doi: 10.1007/s10545-010-9121-7. Epub 2010 Jun 8. Review.


Cleavage of the retinal pigment epithelium-specific protein RPE65 under oxidative stress.

Lee H, Chung H, Arnouk H, Lamoke F, Hunt RC, Hrushesky WJ, Wood PA, Lee SH, Jahng WJ.

Int J Biol Macromol. 2010 Aug 1;47(2):104-8. doi: 10.1016/j.ijbiomac.2010.05.014. Epub 2010 May 25.


Resistance to high-fat diet-induced obesity and insulin resistance in mice with very long-chain acyl-CoA dehydrogenase deficiency.

Zhang D, Christianson J, Liu ZX, Tian L, Choi CS, Neschen S, Dong J, Wood PA, Shulman GI.

Cell Metab. 2010 May 5;11(5):402-11. doi: 10.1016/j.cmet.2010.03.012. Erratum in: Cell Metab. 2010 Jul 4;12(1):103.


Prediction of framework-guest systems using molecular docking.

Korb O, Wood PA.

Chem Commun (Camb). 2010 May 21;46(19):3318-20. doi: 10.1039/c003080e. Epub 2010 Mar 22.


Melatonin reprogrammes proteomic profile in light-exposed retina in vivo.

Zhang R, Hrushesky WJ, Wood PA, Lee SH, Hunt RC, Jahng WJ.

Int J Biol Macromol. 2010 Aug 1;47(2):255-60. doi: 10.1016/j.ijbiomac.2010.04.013. Epub 2010 Apr 29.


WebCSD: the online portal to the Cambridge Structural Database.

Thomas IR, Bruno IJ, Cole JC, Macrae CF, Pidcock E, Wood PA.

J Appl Crystallogr. 2010 Apr 1;43(Pt 2):362-366. Epub 2010 Feb 12.


Lessening Homelessness Among Persons with Mental Illness: A Comparison of Five Randomized Treatment Trials.

Schutt RK, Hough RL, Goldfinger SM, Lehman AF, Shern DL, Valencia E, Wood PA.

Asian J Psychiatr. 2009 Oct 1;2(3):100-102.


Global breast cancer seasonality.

Oh EY, Ansell C, Nawaz H, Yang CH, Wood PA, Hrushesky WJ.

Breast Cancer Res Treat. 2010 Aug;123(1):233-43. doi: 10.1007/s10549-009-0676-7. Epub 2010 Feb 4.


Clock genes and cancer.

Wood PA, Yang X, Hrushesky WJ.

Integr Cancer Ther. 2009 Dec;8(4):303-8. doi: 10.1177/1534735409355292.


Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control.

Yang X, Wood PA, Hrushesky WJ.

J Biol Chem. 2010 Jan 29;285(5):3030-4. doi: 10.1074/jbc.M109.050237. Epub 2009 Dec 7.


Circadian time-dependent tumor suppressor function of period genes.

Yang X, Wood PA, Ansell C, Hrushesky WJ.

Integr Cancer Ther. 2009 Dec;8(4):309-16. doi: 10.1177/1534735409352083. Epub 2009 Nov 18.


The circadian clock gene Per1 suppresses cancer cell proliferation and tumor growth at specific times of day.

Yang X, Wood PA, Ansell CM, Quiton DF, Oh EY, Du-Quiton J, Hrushesky WJ.

Chronobiol Int. 2009 Oct;26(7):1323-39. doi: 10.3109/07420520903431301.


Connecting the dots: obesity, fatty acids and cancer.

Wood PA.

Lab Invest. 2009 Nov;89(11):1192-4. doi: 10.1038/labinvest.2009.99.


Cardiac hypertrophy in mice with long-chain acyl-CoA dehydrogenase or very long-chain acyl-CoA dehydrogenase deficiency.

Cox KB, Liu J, Tian L, Barnes S, Yang Q, Wood PA.

Lab Invest. 2009 Dec;89(12):1348-54. doi: 10.1038/labinvest.2009.86. Epub 2009 Sep 7.


Imaging multidimensional therapeutically relevant circadian relationships.

Singletary J, Wood PA, Du-Quiton J, Wang S, Yang X, Vishnoi S, Hrushesky WJ.

Int J Biomed Imaging. 2009;2009:231539. doi: 10.1155/2009/231539. Epub 2009 Aug 16.


Transgenic expression of n-3 fatty acid desaturase (fat-1) in C57/BL6 mice: Effects on glucose homeostasis and body weight.

Ji S, Hardy RW, Wood PA.

J Cell Biochem. 2009 Jul 1;107(4):809-17. doi: 10.1002/jcb.22179.


Neuroprotective role of erythropoietin by antiapoptosis in the retina.

Chung H, Lee H, Lamoke F, Hrushesky WJ, Wood PA, Jahng WJ.

J Neurosci Res. 2009 Aug 1;87(10):2365-74. doi: 10.1002/jnr.22046.


Synthesis, characterisation and photochemistry of Pt(IV) pyridyl azido acetato complexes.

Mackay FS, Farrer NJ, Salassa L, Tai HC, Deeth RJ, Moggach SA, Wood PA, Parsons S, Sadler PJ.

Dalton Trans. 2009 Apr 7;(13):2315-25. doi: 10.1039/b820550g. Epub 2009 Feb 24.


Actigraphic assessment of daily sleep-activity pattern abnormalities reflects self-assessed depression and anxiety in outpatients with advanced non-small cell lung cancer.

Du-Quiton J, Wood PA, Burch JB, Grutsch JF, Gupta D, Tyer K, Lis CG, Levin RD, Quiton DF, Reynolds JL, Hrushesky WJ.

Psychooncology. 2010 Feb;19(2):180-9. doi: 10.1002/pon.1539.


3-Fluoro-salicylaldoxime at 6.5 GPa.

Wood PA, Forgan RS, Parsons S, Pidcock E, Tasker PA.

Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 25;65(Pt 8):o2001. doi: 10.1107/S1600536809029043.


Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.

Yang X, Wood PA, Ansell CM, Ohmori M, Oh EY, Xiong Y, Berger FG, Peña MM, Hrushesky WJ.

J Biochem. 2009 Mar;145(3):289-97. doi: 10.1093/jb/mvn167. Epub 2008 Dec 23.


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