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Doublecortin like kinase 1 regulates α-Synuclein levels and toxicity.

Vázquez-Vélez GE, Gonzales KA, Revelli JP, Adamski CJ, Alavi Naini F, Bajić A, Craigen E, Richman R, Heman-Ackah SM, Wood MJA, Rousseaux MWC, Zoghbi HY.

J Neurosci. 2019 Nov 20. pii: 1076-19. doi: 10.1523/JNEUROSCI.1076-19.2019. [Epub ahead of print]


Targeting of tolerogenic dendritic cells to heat-shock proteins in inflammatory arthritis.

Spiering R, Jansen MAA, Wood MJ, Fath AA, Eltherington O, Anderson AE, Pratt AG, van Eden W, Isaacs JD, Broere F, Hilkens CMU.

J Transl Med. 2019 Nov 14;17(1):375. doi: 10.1186/s12967-019-2128-4.


Considerations and Implications in the Purification of Extracellular Vesicles - A Cautionary Tale.

Lee YXF, Johansson H, Wood MJA, El Andaloussi S.

Front Neurosci. 2019 Oct 18;13:1067. doi: 10.3389/fnins.2019.01067. eCollection 2019.


Association of tramadol with risk of myocardial infarction among patients with osteoarthritis.

Wei J, Wood MJ, Dubreuil M, Tomasson G, LaRochelle MR, Zeng C, Lu N, Lin J, Choi HK, Lei G, Zhang Y.

Osteoarthritis Cartilage. 2019 Oct 16. pii: S1063-4584(19)31225-7. doi: 10.1016/j.joca.2019.10.001. [Epub ahead of print]


Africa - first institute for neuroscience.

Fieggen AG, Donald KA, Stein DJ, Wood MJA.

Nature. 2019 Oct;574(7778):333. doi: 10.1038/d41586-019-03108-z. No abstract available.


Imaging of Metastatic Germ Cell Tumors in Male Patients From Initial Diagnosis to Treatment-Related Toxicities: A Primer for Radiologists.

Wood MJ, Thomas R, Howard SA, Braschi-Amirfarzan M.

AJR Am J Roentgenol. 2019 Oct 1:1-10. doi: 10.2214/AJR.19.21623. [Epub ahead of print]


Wrangling RNA: Antisense oligonucleotides for neurological disorders.

Talbot K, Wood MJA.

Sci Transl Med. 2019 Sep 25;11(511). pii: eaay2069. doi: 10.1126/scitranslmed.aay2069. Review.


Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice.

Klein AF, Varela MA, Arandel L, Holland A, Naouar N, Arzumanov A, Seoane D, Revillod L, Bassez G, Ferry A, Jauvin D, Gourdon G, Puymirat J, Gait MJ, Furling D, Wood MJ.

J Clin Invest. 2019 Nov 1;129(11):4739-4744. doi: 10.1172/JCI128205.


Sampling strategies for species with high breeding-site fidelity: A case study in burrow-nesting seabirds.

Arneill GE, Perrins CM, Wood MJ, Murphy D, Pisani L, Jessopp MJ, Quinn JL.

PLoS One. 2019 Aug 27;14(8):e0221625. doi: 10.1371/journal.pone.0221625. eCollection 2019.


Evaluation of Cell-Penetrating Peptide Delivery of Antisense Oligonucleotides for Therapeutic Efficacy in Spinal Muscular Atrophy.

Hammond SM, Abendroth F, Gait MJ, Wood MJA.

Methods Mol Biol. 2019;2036:221-236. doi: 10.1007/978-1-4939-9670-4_13.


Terrestrial emigration behaviour of two invasive crayfish species.

Thomas JR, Masefield S, Hunt R, Wood MJ, Hart AG, Hallam J, Griffiths SW, Cable J.

Behav Processes. 2019 Oct;167:103917. doi: 10.1016/j.beproc.2019.103917. Epub 2019 Jul 23.


Peptide-conjugate antisense based splice-correction for Duchenne muscular dystrophy and other neuromuscular diseases.

Tsoumpra MK, Fukumoto S, Matsumoto T, Takeda S, Wood MJA, Aoki Y.

EBioMedicine. 2019 Jul;45:630-645. doi: 10.1016/j.ebiom.2019.06.036. Epub 2019 Jun 27. Review.


Left ventricular vortex formation time in elite athletes: novel predictor of myocardial performance.

Poh KK, Ngiam N, Wood MJ.

Heart Asia. 2019 Apr 24;11(1):e011188. doi: 10.1136/heartasia-2019-011188. eCollection 2019.


The viral protein corona directs viral pathogenesis and amyloid aggregation.

Ezzat K, Pernemalm M, Pålsson S, Roberts TC, Järver P, Dondalska A, Bestas B, Sobkowiak MJ, Levänen B, Sköld M, Thompson EA, Saher O, Kari OK, Lajunen T, Sverremark Ekström E, Nilsson C, Ishchenko Y, Malm T, Wood MJA, Power UF, Masich S, Lindén A, Sandberg JK, Lehtiö J, Spetz AL, El Andaloussi S.

Nat Commun. 2019 May 27;10(1):2331. doi: 10.1038/s41467-019-10192-2.


Spontaneous coronary artery dissection and its association with takotsubo syndrome: Novel insights from a tertiary center registry.

Duran JM, Naderi S, Vidula M, Michalak N, Chi G, Lindsay M, Ghoshhajra B, Gibson CM, Wood MJ.

Catheter Cardiovasc Interv. 2019 Apr 29. doi: 10.1002/ccd.28314. [Epub ahead of print]


The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy.

Guiraud S, Edwards B, Babbs A, Squire SE, Berg A, Moir L, Wood MJ, Davies KE.

Hum Mol Genet. 2019 Jul 1;28(13):2189-2200. doi: 10.1093/hmg/ddz049.


Risk Factors, Imaging Findings, and Sex Differences in Spontaneous Coronary Artery Dissection.

Sharma S, Kaadan MI, Duran JM, Ponzini F, Mishra S, Tsiaras SV, Scott NS, Weinberg I, Ghoshhajra B, Lindsay M, Gibson CM, Chi G, Michalak N, Wood MJ.

Am J Cardiol. 2019 Jun 1;123(11):1783-1787. doi: 10.1016/j.amjcard.2019.02.040. Epub 2019 Mar 8.


Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking.

Murphy DE, de Jong OG, Brouwer M, Wood MJ, Lavieu G, Schiffelers RM, Vader P.

Exp Mol Med. 2019 Mar 15;51(3):32. doi: 10.1038/s12276-019-0223-5. Review.


Extracellular microRNAs exhibit sequence-dependent stability and cellular release kinetics.

Coenen-Stass AML, Pauwels MJ, Hanson B, Martin Perez C, Conceição M, Wood MJA, Mäger I, Roberts TC.

RNA Biol. 2019 May;16(5):696-706. doi: 10.1080/15476286.2019.1582956. Epub 2019 Mar 5.


Left ventricular vortex formation time in elite athletes.

King G, Ngiam N, Clarke J, Wood MJ, Poh KK.

Int J Cardiovasc Imaging. 2019 Feb;35(2):307-311. doi: 10.1007/s10554-019-01561-5. Epub 2019 Mar 2.


Macrophage proliferation distinguishes 2 subgroups of knee osteoarthritis patients.

Wood MJ, Leckenby A, Reynolds G, Spiering R, Pratt AG, Rankin KS, Isaacs JD, Haniffa MA, Milling S, Hilkens CM.

JCI Insight. 2019 Jan 24;4(2). pii: 125325. doi: 10.1172/jci.insight.125325. [Epub ahead of print]


Can drones count gulls? Minimal disturbance and semiautomated image processing with an unmanned aerial vehicle for colony-nesting seabirds.

Rush GP, Clarke LE, Stone M, Wood MJ.

Ecol Evol. 2018 Dec 4;8(24):12322-12334. doi: 10.1002/ece3.4495. eCollection 2018 Dec.


The Need for a Machine Learning Curriculum for Radiologists.

Wood MJ, Tenenholtz NA, Geis JR, Michalski MH, Andriole KP.

J Am Coll Radiol. 2019 May;16(5):740-742. doi: 10.1016/j.jacr.2018.10.008. Epub 2018 Dec 7. No abstract available.


Where are the women in academic cardiology?

DeFilippis EM, Lau ES, Wei J, Hayes SN, Wood MJ.

Lancet. 2018 Nov 17;392(10160):2152-2153. doi: 10.1016/S0140-6736(18)32618-7. No abstract available.


Valvular Heart Disease and Heart Failure in Women.

Crousillat DR, Wood MJ.

Heart Fail Clin. 2019 Jan;15(1):77-85. doi: 10.1016/j.hfc.2018.08.008. Review.


A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.

Yin H, Moulton HM, Betts C, Seow Y, Boutilier J, Iverson PL, Wood MJA.

Hum Mol Genet. 2019 Feb 15;28(4):699. doi: 10.1093/hmg/ddy377. No abstract available.


Heart Centers for Women.

Lundberg GP, Mehta LS, Sanghani RM, Patel HN, Aggarwal NR, Aggarwal NT, Braun LT, Lewis SJ, Mieres JH, Wood MJ, Harrington RA, Volgman AS.

Circulation. 2018 Sep 11;138(11):1155-1165. doi: 10.1161/CIRCULATIONAHA.118.035351. Review.


Cell-Penetrating Peptide Conjugates of Steric Blocking Oligonucleotides as Therapeutics for Neuromuscular Diseases from a Historical Perspective to Current Prospects of Treatment.

Gait MJ, Arzumanov AA, McClorey G, Godfrey C, Betts C, Hammond S, Wood MJA.

Nucleic Acid Ther. 2019 Feb;29(1):1-12. doi: 10.1089/nat.2018.0747. Epub 2018 Oct 16.


Embryonic myosin is a regeneration marker to monitor utrophin-based therapies for DMD.

Guiraud S, Edwards B, Squire SE, Moir L, Berg A, Babbs A, Ramadan N, Wood MJ, Davies KE.

Hum Mol Genet. 2019 Jan 15;28(2):307-319. doi: 10.1093/hmg/ddy353.


Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.

Betts CA, McClorey G, Healicon R, Hammond SM, Manzano R, Muses S, Ball V, Godfrey C, Merritt TM, van Westering T, O'Donovan L, Wells KE, Gait MJ, Wells DJ, Tyler D, Wood MJ.

Hum Mol Genet. 2019 Feb 1;28(3):396-406. doi: 10.1093/hmg/ddy346.


Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD.

Coenen-Stass AML, Sork H, Gatto S, Godfrey C, Bhomra A, Krjutškov K, Hart JR, Westholm JO, O'Donovan L, Roos A, Lochmüller H, Puri PL, El Andaloussi S, Wood MJA, Roberts TC.

Mol Ther Nucleic Acids. 2018 Dec 7;13:1-15. doi: 10.1016/j.omtn.2018.08.005. Epub 2018 Aug 17.


The Global Burden of Cardiovascular Disease in Women.

Sharma S, Wood MJ.

Curr Treat Options Cardiovasc Med. 2018 Aug 27;20(10):81. doi: 10.1007/s11936-018-0676-1. Review.


Propagating and Debunking Conspiracy Theories on Twitter During the 2015-2016 Zika Virus Outbreak.

Wood MJ.

Cyberpsychol Behav Soc Netw. 2018 Aug;21(8):485-490. doi: 10.1089/cyber.2017.0669. Epub 2018 Jul 18.


Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome.

Sork H, Corso G, Krjutskov K, Johansson HJ, Nordin JZ, Wiklander OPB, Lee YXF, Westholm JO, Lehtiö J, Wood MJA, Mäger I, El Andaloussi S.

Sci Rep. 2018 Jul 17;8(1):10813. doi: 10.1038/s41598-018-28485-9.


Light modulation ameliorates expression of circadian genes and disease progression in spinal muscular atrophy mice.

Walter LM, Koch CE, Betts CA, Ahlskog N, Meijboom KE, van Westering TLE, Hazell G, Bhomra A, Claus P, Oster H, Wood MJA, Bowerman M.

Hum Mol Genet. 2018 Oct 15;27(20):3582-3597. doi: 10.1093/hmg/ddy249.


Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy.

Blain AM, Greally E, McClorey G, Manzano R, Betts CA, Godfrey C, O'Donovan L, Coursindel T, Gait MJ, Wood MJ, MacGowan GA, Straub VW.

PLoS One. 2018 Jun 18;13(6):e0198897. doi: 10.1371/journal.pone.0198897. eCollection 2018.


Extracellular Vesicle Heterogeneity: Subpopulations, Isolation Techniques, and Diverse Functions in Cancer Progression.

Willms E, Cabañas C, Mäger I, Wood MJA, Vader P.

Front Immunol. 2018 Apr 30;9:738. doi: 10.3389/fimmu.2018.00738. eCollection 2018. Review.


Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice.

Walter LM, Deguise MO, Meijboom KE, Betts CA, Ahlskog N, van Westering TLE, Hazell G, McFall E, Kordala A, Hammond SM, Abendroth F, Murray LM, Shorrock HK, Prosdocimo DA, Haldar SM, Jain MK, Gillingwater TH, Claus P, Kothary R, Wood MJA, Bowerman M.

EBioMedicine. 2018 May;31:226-242. doi: 10.1016/j.ebiom.2018.04.024. Epub 2018 May 4.


Prospective Cardiovascular Genetics Evaluation in Spontaneous Coronary Artery Dissection.

Kaadan MI, MacDonald C, Ponzini F, Duran J, Newell K, Pitler L, Lin A, Weinberg I, Wood MJ, Lindsay ME.

Circ Genom Precis Med. 2018 Apr;11(4):e001933. doi: 10.1161/CIRCGENETICS.117.001933.


Using domiciliary non-invasive ventilator data downloads to inform clinical decision-making to optimise ventilation delivery and patient compliance.

Mansell SK, Cutts S, Hackney I, Wood MJ, Hawksworth K, Creer DD, Kilbride C, Mandal S.

BMJ Open Respir Res. 2018 Mar 3;5(1):e000238. doi: 10.1136/bmjresp-2017-000238. eCollection 2018.


How do we attract and retain women in cardiology?

Lau ES, Wood MJ.

Clin Cardiol. 2018 Feb;41(2):264-268. doi: 10.1002/clc.22921. Epub 2018 Feb 26. Review.


Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association.

Hayes SN, Kim ESH, Saw J, Adlam D, Arslanian-Engoren C, Economy KE, Ganesh SK, Gulati R, Lindsay ME, Mieres JH, Naderi S, Shah S, Thaler DE, Tweet MS, Wood MJ; American Heart Association Council on Peripheral Vascular Disease; Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Genomic and Precision Medicine; and Stroke Council.

Circulation. 2018 May 8;137(19):e523-e557. doi: 10.1161/CIR.0000000000000564. Epub 2018 Feb 22. Review.


Sex Differences in Ischemic Heart Disease: Advances, Obstacles, and Next Steps.

Aggarwal NR, Patel HN, Mehta LS, Sanghani RM, Lundberg GP, Lewis SJ, Mendelson MA, Wood MJ, Volgman AS, Mieres JH.

Circ Cardiovasc Qual Outcomes. 2018 Feb;11(2):e004437. doi: 10.1161/CIRCOUTCOMES.117.004437. Review.


Case 39-2017. A 41-Year-Old Woman with Recurrent Chest Pain.

Tsiaras SV, Safi LM, Ghoshhajra BB, Lindsay ME, Wood MJ.

N Engl J Med. 2017 Dec 21;377(25):2475-2484. doi: 10.1056/NEJMcpc1707558. No abstract available.


Antisense oligonucleotides: the next frontier for treatment of neurological disorders.

Rinaldi C, Wood MJA.

Nat Rev Neurol. 2018 Jan;14(1):9-21. doi: 10.1038/nrneurol.2017.148. Epub 2017 Dec 1. Review.


Biomarker Potential of Extracellular miRNAs in Duchenne Muscular Dystrophy.

Coenen-Stass AML, Wood MJA, Roberts TC.

Trends Mol Med. 2017 Nov;23(11):989-1001. doi: 10.1016/j.molmed.2017.09.002. Epub 2017 Oct 5. Review.


Performance and Interpretation Training of Transthoracic Echocardiography in Resource-Limited Settings.

Bennet CS, Abeya FC, Hoffman A, Rwebembera J, Picard MH, Wood MJ, Okello S.

J Am Coll Cardiol. 2017 Oct 10;70(15):1940-1941. doi: 10.1016/j.jacc.2017.08.015. No abstract available.


Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape.

Wood MJA, Talbot K, Bowerman M.

Hum Mol Genet. 2017 Oct 1;26(R2):R151-R159. doi: 10.1093/hmg/ddx215. Review.


Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons.

Heman-Ackah SM, Manzano R, Hoozemans JJM, Scheper W, Flynn R, Haerty W, Cowley SA, Bassett AR, Wood MJA.

Hum Mol Genet. 2017 Nov 15;26(22):4441-4450. doi: 10.1093/hmg/ddx331.


Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography.

Corso G, Mäger I, Lee Y, Görgens A, Bultema J, Giebel B, Wood MJA, Nordin JZ, Andaloussi SE.

Sci Rep. 2017 Sep 14;7(1):11561. doi: 10.1038/s41598-017-10646-x.

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