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Mouse genetics reveals Barttin as a genetic modifier of Joubert syndrome.

Ramsbottom SA, Thelwall PE, Wood KM, Clowry GJ, Devlin LA, Silbermann F, Spiewak HL, Shril S, Molinari E, Hildebrandt F, Gunay-Aygun M, Saunier S, Cordell HJ, Sayer JA, Miles CG.

Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1113-1118. doi: 10.1073/pnas.1912602117. Epub 2019 Dec 26.


A humanized yeast system to analyze cleavage of prelamin A by ZMPSTE24.

Spear ED, Alford RF, Babatz TD, Wood KM, Mossberg OW, Odinammadu K, Shilagardi K, Gray JJ, Michaelis S.

Methods. 2019 Mar 15;157:47-55. doi: 10.1016/j.ymeth.2019.01.001. Epub 2019 Jan 6. Review.


Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma.

Chen L, Pastorino F, Berry P, Bonner J, Kirk C, Wood KM, Thomas HD, Zhao Y, Daga A, Veal GJ, Lunec J, Newell DR, Ponzoni M, Tweddle DA.

Int J Cancer. 2019 Jun 15;144(12):3146-3159. doi: 10.1002/ijc.32058. Epub 2019 Jan 9.


Naval Medicine's Involvement in Global Health: The Participation of Women's Healthcare Providers in Continuing Promise 2017.

Wood KM, Ellison C, Magann EF.

Mil Med. 2019 Mar 1;184(3-4):e135-e138. doi: 10.1093/milmed/usy208.


A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing.

Finn JD, Smith AR, Patel MC, Shaw L, Youniss MR, van Heteren J, Dirstine T, Ciullo C, Lescarbeau R, Seitzer J, Shah RR, Shah A, Ling D, Growe J, Pink M, Rohde E, Wood KM, Salomon WE, Harrington WF, Dombrowski C, Strapps WR, Chang Y, Morrissey DV.

Cell Rep. 2018 Feb 27;22(9):2227-2235. doi: 10.1016/j.celrep.2018.02.014.


Effect of ruminal acidosis and short-term low feed intake on indicators of gastrointestinal barrier function in Holstein steers.

Pederzolli RA, Van Kessel AG, Campbell J, Hendrick S, Wood KM, Penner GB.

J Anim Sci. 2018 Feb 15;96(1):108-125. doi: 10.1093/jas/skx049.


Lessons from animal nutritionists: dietary amino acid requirement studies and considerations for healthy aging studies.

Shoveller AK, McKnight LM, Wood KM, Cant JP.

Ann N Y Acad Sci. 2018 Apr;1418(1):20-30. doi: 10.1111/nyas.13546. Epub 2018 Jan 24. Review.


The Real-World Effect of Intravitreous Anti-Vascular Endothelial Growth Factor Drugs on Intraocular Pressure: An Analysis Using the IRIS Registry.

Atchison EA, Wood KM, Mattox CG, Barry CN, Lum F, MacCumber MW.

Ophthalmology. 2018 May;125(5):676-682. doi: 10.1016/j.ophtha.2017.11.027. Epub 2018 Jan 11.


Thrombotic Microangiopathy and the Kidney.

Brocklebank V, Wood KM, Kavanagh D.

Clin J Am Soc Nephrol. 2018 Feb 7;13(2):300-317. doi: 10.2215/CJN.00620117. Epub 2017 Oct 17. Review.


Maternal nutrient restriction in mid-to-late gestation influences fetal mRNA expression in muscle tissues in beef cattle.

Paradis F, Wood KM, Swanson KC, Miller SP, McBride BW, Fitzsimmons C.

BMC Genomics. 2017 Aug 18;18(1):632. doi: 10.1186/s12864-017-4051-5.


Thrombotic Microangiopathy in Inverted Formin 2-Mediated Renal Disease.

Challis RC, Ring T, Xu Y, Wong EK, Flossmann O, Roberts IS, Ahmed S, Wetherall M, Salkus G, Brocklebank V, Fester J, Strain L, Wilson V, Wood KM, Marchbank KJ, Santibanez-Koref M, Goodship TH, Kavanagh D.

J Am Soc Nephrol. 2017 Apr;28(4):1084-1091. doi: 10.1681/ASN.2015101189. Epub 2016 Dec 14.


Effects of subacute ruminal acidosis and low feed intake on short-chain fatty acid transporters and flux pathways in Holstein steers.

Laarman AH, Pederzolli RA, Wood KM, Penner GB, McBride BW.

J Anim Sci. 2016 Sep;94(9):3729-3737. doi: 10.2527/jas.2016-0638.


Discovery of cyclopropyl chromane-derived pyridopyrazine-1,6-dione γ-secretase modulators with robust central efficacy.

Pettersson M, Johnson DS, Rankic DA, Kauffman GW, Am Ende CW, Butler TW, Boscoe B, Evrard E, Helal CJ, Humphrey JM, Stepan AF, Stiff CM, Yang E, Xie L, Bales KR, Hajos-Korcsok E, Jenkinson S, Pettersen B, Pustilnik LR, Ramirez DS, Steyn SJ, Wood KM, Verhoest PR.

Medchemcomm. 2016 Nov 2;8(4):730-743. doi: 10.1039/c6md00406g. eCollection 2017 Apr 1.


Patterns of Drug Use and Serum Sodium Concentrations in Older Hospitalized Patients: A Latent Class Analysis Approach.

Woodman RJ, Wood KM, Kunnel A, Dedigama M, Pegoli MA, Soiza RL, Mangoni AA.

Drugs Real World Outcomes. 2016 Dec;3(4):383-391.


High-Intensity Interval Training Increases Cardiac Output and V˙O2max.

Astorino TA, Edmunds RM, Clark A, King L, Gallant RA, Namm S, Fischer A, Wood KM.

Med Sci Sports Exerc. 2017 Feb;49(2):265-273. doi: 10.1249/MSS.0000000000001099.


Modulation of serotonin dynamics in the dorsal raphe nucleus via high frequency medial prefrontal cortex stimulation.

Srejic LR, Wood KM, Zeqja A, Hashemi P, Hutchison WD.

Neurobiol Dis. 2016 Oct;94:129-38. doi: 10.1016/j.nbd.2016.06.009. Epub 2016 Jun 17.


Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury.

Cocchiaro P, Fox C, Tregidgo NW, Howarth R, Wood KM, Situmorang GR, Pavone LM, Sheerin NS, Moles A.

Sci Rep. 2016 Jun 7;6:27112. doi: 10.1038/srep27112.


Myeloproliferative neoplasm with eosinophilia and T-lymphoblastic lymphoma with ETV6-LYN gene fusion.

Telford N, Alexander S, McGinn OJ, Williams M, Wood KM, Bloor A, Saha V.

Blood Cancer J. 2016 Apr 8;6:e412. doi: 10.1038/bcj.2016.11. No abstract available.


Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich's ataxia.

Nabhan JF, Wood KM, Rao VP, Morin J, Bhamidipaty S, LaBranche TP, Gooch RL, Bozal F, Bulawa CE, Guild BC.

Sci Rep. 2016 Feb 17;6:20019. doi: 10.1038/srep20019.


Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease.

Fox C, Cocchiaro P, Oakley F, Howarth R, Callaghan K, Leslie J, Luli S, Wood KM, Genovese F, Sheerin NS, Moles A.

Sci Rep. 2016 Feb 2;6:20101. doi: 10.1038/srep20101.


Dissimilar Physiological and Perceptual Responses Between Sprint Interval Training and High-Intensity Interval Training.

Wood KM, Olive B, LaValle K, Thompson H, Greer K, Astorino TA.

J Strength Cond Res. 2016 Jan;30(1):244-50. doi: 10.1519/JSC.0000000000001042.


Passive immunotherapy targeting amyloid-β reduces cerebral amyloid angiopathy and improves vascular reactivity.

Bales KR, O'Neill SM, Pozdnyakov N, Pan F, Caouette D, Pi Y, Wood KM, Volfson D, Cirrito JR, Han BH, Johnson AW, Zipfel GJ, Samad TA.

Brain. 2016 Feb;139(Pt 2):563-77. doi: 10.1093/brain/awv313. Epub 2015 Oct 22.


The influence of age and weaning on permeability of the gastrointestinal tract in Holstein bull calves.

Wood KM, Palmer SI, Steele MA, Metcalf JA, Penner GB.

J Dairy Sci. 2015 Oct;98(10):7226-37. doi: 10.3168/jds.2015-9393. Epub 2015 Aug 13.


Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability.

Pettersson M, Johnson DS, Humphrey JM, Butler TW, Am Ende CW, Fish BA, Green ME, Kauffman GW, Mullins PB, O'Donnell CJ, Stepan AF, Stiff CM, Subramanyam C, Tran TP, Vetelino BC, Yang E, Xie L, Bales KR, Pustilnik LR, Steyn SJ, Wood KM, Verhoest PR.

ACS Med Chem Lett. 2015 Apr 3;6(5):596-601. doi: 10.1021/acsmedchemlett.5b00070. eCollection 2015 May 14.


In vivo histamine voltammetry in the mouse premammillary nucleus.

Samaranayake S, Abdalla A, Robke R, Wood KM, Zeqja A, Hashemi P.

Analyst. 2015 Jun 7;140(11):3759-65. doi: 10.1039/c5an00313j.


Discovery of indole-derived pyridopyrazine-1,6-dione γ-secretase modulators that target presenilin.

Pettersson M, Johnson DS, Humphrey JM, Am Ende CW, Evrard E, Efremov I, Kauffman GW, Stepan AF, Stiff CM, Xie L, Bales KR, Hajos-Korcsok E, Murrey HE, Pustilnik LR, Steyn SJ, Wood KM, Verhoest PR.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):908-13. doi: 10.1016/j.bmcl.2014.12.059. Epub 2014 Dec 25.


The coaction of tonic and phasic dopamine dynamics.

Atcherley CW, Wood KM, Parent KL, Hashemi P, Heien ML.

Chem Commun (Camb). 2015 Feb 11;51(12):2235-8. doi: 10.1039/c4cc06165a.


Improved Calibration of Voltammetric Sensors for Studying Pharmacological Effects on Dopamine Transporter Kinetics in Vivo.

Atcherley CW, Laude ND, Monroe EB, Wood KM, Hashemi P, Heien ML.

ACS Chem Neurosci. 2015 Sep 16;6(9):1509-16. doi: 10.1021/cn500020s. Epub 2014 Jul 25.


Utility of echocardiography in identifying right ventricular extension of Wilm's tumor.

Iyer P, Sibal N, Chaudhari M, Wood KM, Campbell-Hewson Q.

J Clin Ultrasound. 2015 May;43(4):262-264. doi: 10.1002/jcu.22174. Epub 2014 May 28.


Surface histidine mutations for the metal affinity purification of a β-carbonic anhydrase.

Hoffmann KM, Wood KM, Labrum AD, Lee DK, Bolinger IM, Konis ME, Blount AG, Prussia GA, Schroll MM, Watson JM.

Anal Biochem. 2014 Aug 1;458:66-8. doi: 10.1016/j.ab.2014.04.020. Epub 2014 Apr 30.


Voltammetric and mathematical evidence for dual transport mediation of serotonin clearance in vivo.

Wood KM, Zeqja A, Nijhout HF, Reed MC, Best J, Hashemi P.

J Neurochem. 2014 Aug;130(3):351-9. doi: 10.1111/jnc.12733. Epub 2014 Apr 26.


Design, synthesis, and pharmacological evaluation of a novel series of pyridopyrazine-1,6-dione γ-secretase modulators.

Pettersson M, Johnson DS, Subramanyam C, Bales KR, am Ende CW, Fish BA, Green ME, Kauffman GW, Mullins PB, Navaratnam T, Sakya SM, Stiff CM, Tran TP, Xie L, Zhang L, Pustilnik LR, Vetelino BC, Wood KM, Pozdnyakov N, Verhoest PR, O'Donnell CJ.

J Med Chem. 2014 Feb 13;57(3):1046-62. doi: 10.1021/jm401782h. Epub 2014 Jan 28.


Hyponatremia: Special Considerations in Older Patients.

Soiza RL, Cumming K, Clarke JM, Wood KM, Myint PK.

J Clin Med. 2014 Aug 18;3(3):944-58. doi: 10.3390/jcm3030944. Review.


Influence of pregnancy in mid-to-late gestation on circulating metabolites, visceral organ mass, and abundance of proteins relating to energy metabolism in mature beef cows.

Wood KM, Awda BJ, Fitzsimmons C, Miller SP, McBride BW, Swanson KC.

J Anim Sci. 2013 Dec;91(12):5775-84. doi: 10.2527/jas.2013-6589. Epub 2013 Oct 21.


Effect of moderate dietary restriction on visceral organ weight, hepatic oxygen consumption, and metabolic proteins associated with energy balance in mature pregnant beef cows.

Wood KM, Awda BJ, Fitzsimmons C, Miller SP, McBride BW, Swanson KC.

J Anim Sci. 2013 Sep;91(9):4245-55. doi: 10.2527/jas.2013-6421. Epub 2013 Jul 26.


Genotype/phenotype correlations in complement factor H deficiency arising from uniparental isodisomy.

Wilson V, Darlay R, Wong W, Wood KM, McFarlane J, Schejbel L, Schmidt IM, Harris CL, Tellez J, Hunze EM, Marchbank K, Goodship JA, Goodship TH.

Am J Kidney Dis. 2013 Nov;62(5):978-83. doi: 10.1053/j.ajkd.2013.05.020. Epub 2013 Jul 16.


Fast-scan cyclic voltammetry analysis of dynamic serotonin reponses to acute escitalopram.

Wood KM, Hashemi P.

ACS Chem Neurosci. 2013 May 15;4(5):715-20. doi: 10.1021/cn4000378. Epub 2013 Apr 24.


Influence of feeding increasing levels of dry corn distillers grains plus solubles in whole corn grain-based finishing diets on total tract digestion, nutrient balance, and excretion in beef steers.

Salim H, Wood KM, Abo-Ismail MK, McEwen PL, Mandell IB, Miller SP, Cant JP, Swanson KC.

J Anim Sci. 2012 Dec;90(12):4441-8. doi: 10.2527/jas.2011-4332. Epub 2012 Sep 5.


Cerebrospinal fluid β-Amyloid turnover in the mouse, dog, monkey and human evaluated by systematic quantitative analyses.

Lu Y, Barton HA, Leung L, Zhang L, Hajos-Korcsok E, Nolan CE, Liu J, Becker SL, Wood KM, Robshaw AE, Taylor CK, O'Neill BT, Brodney MA, Riddell D.

Neurodegener Dis. 2013;12(1):36-50. doi: 10.1159/000341217. Epub 2012 Aug 21.


A dysregulated endocannabinoid-eicosanoid network supports pathogenesis in a mouse model of Alzheimer's disease.

Piro JR, Benjamin DI, Duerr JM, Pi Y, Gonzales C, Wood KM, Schwartz JW, Nomura DK, Samad TA.

Cell Rep. 2012 Jun 28;1(6):617-23. doi: 10.1016/j.celrep.2012.05.001. Epub 2012 Jun 21.


Brain dopamine and serotonin differ in regulation and its consequences.

Hashemi P, Dankoski EC, Lama R, Wood KM, Takmakov P, Wightman RM.

Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11510-5. doi: 10.1073/pnas.1201547109. Epub 2012 Jul 9.


Diarrhea etiology in a pediatric emergency department: a case control study.

Denno DM, Shaikh N, Stapp JR, Qin X, Hutter CM, Hoffman V, Mooney JC, Wood KM, Stevens HJ, Jones R, Tarr PI, Klein EJ.

Clin Infect Dis. 2012 Oct;55(7):897-904. doi: 10.1093/cid/cis553. Epub 2012 Jun 14.


Evaluation of treatment outcome in 175 patients with Hodgkin lymphoma aged 60 years or over: the SHIELD study.

Proctor SJ, Wilkinson J, Jones G, Watson GC, Lucraft HH, Mainou-Fowler T, Culligan D, Galloway MJ, Wood KM, McNally RJ, James PW, Goodlad JR.

Blood. 2012 Jun 21;119(25):6005-15. doi: 10.1182/blood-2011-12-396556. Epub 2012 May 10.


Cerebrospinal fluid amyloid-β (Aβ) as an effect biomarker for brain Aβ lowering verified by quantitative preclinical analyses.

Lu Y, Riddell D, Hajos-Korcsok E, Bales K, Wood KM, Nolan CE, Robshaw AE, Zhang L, Leung L, Becker SL, Tseng E, Barricklow J, Miller EH, Osgood S, O'Neill BT, Brodney MA, Johnson DS, Pettersson M.

J Pharmacol Exp Ther. 2012 Aug;342(2):366-75. doi: 10.1124/jpet.112.192625. Epub 2012 May 4.


Anti-neutrophil cytoplasmic antibody (ANCA) associated small-vessel vasculitis in a patient with diabetic nephropathy and autoimmune polyendocrinopathy syndrome (APS) Type 2: a case report.

Murray JS, Baines LA, Pearce SH, Ball S, Leech N, Wood KM, Kanagasundaram NS.

Clin Nephrol. 2013 Sep;80(3):223-6. doi: 10.5414/CN107142.


Design and synthesis of dihydrobenzofuran amides as orally bioavailable, centrally active γ-secretase modulators.

Pettersson M, Johnson DS, Subramanyam C, Bales KR, am Ende CW, Fish BA, Green ME, Kauffman GW, Lira R, Mullins PB, Navaratnam T, Sakya SM, Stiff CM, Tran TP, Vetelino BC, Xie L, Zhang L, Pustilnik LR, Wood KM, O'Donnell CJ.

Bioorg Med Chem Lett. 2012 Apr 15;22(8):2906-11. doi: 10.1016/j.bmcl.2012.02.059. Epub 2012 Mar 1.


Posttransplant lymphoproliferative disorder presenting as multiple cystic lesions in a renal transplant recipient.

Moir JA, Simms RJ, Wood KM, Talbot D, Kanagasundaram NS.

Am J Transplant. 2012 Jan;12(1):245-9. doi: 10.1111/j.1600-6143.2011.03761.x.

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