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Items: 1 to 50 of 156

1.

Nicotinic acetylcholine receptors.

Wonnacott S, Bermudez I, Millar NS, Tzartos SJ.

Br J Pharmacol. 2018 Jun;175(11):1785-1788. doi: 10.1111/bph.14209.

PMID:
29878346
2.

Inhibition of alpha7 nicotinic receptors in the ventral hippocampus selectively attenuates reinstatement of morphine-conditioned place preference and associated changes in AMPA receptor binding.

Wright VL, Georgiou P, Bailey A, Heal DJ, Bailey CP, Wonnacott S.

Addict Biol. 2018 Apr 17. doi: 10.1111/adb.12624. [Epub ahead of print]

PMID:
29667304
3.

Nicotinic Acetylcholine Receptors Control Encoding and Retrieval of Associative Recognition Memory through Plasticity in the Medial Prefrontal Cortex.

Sabec MH, Wonnacott S, Warburton EC, Bashir ZI.

Cell Rep. 2018 Mar 27;22(13):3409-3415. doi: 10.1016/j.celrep.2018.03.016.

4.

Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers.

Curtis MJ, Alexander S, Cirino G, Docherty JR, George CH, Giembycz MA, Hoyer D, Insel PA, Izzo AA, Ji Y, MacEwan DJ, Sobey CG, Stanford SC, Teixeira MM, Wonnacott S, Ahluwalia A.

Br J Pharmacol. 2018 Apr;175(7):987-993. doi: 10.1111/bph.14153.

PMID:
29520785
5.

Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology.

Alexander SPH, Roberts RE, Broughton BRS, Sobey CG, George CH, Stanford SC, Cirino G, Docherty JR, Giembycz MA, Hoyer D, Insel PA, Izzo AA, Ji Y, MacEwan DJ, Mangum J, Wonnacott S, Ahluwalia A.

Br J Pharmacol. 2018 Feb;175(3):407-411. doi: 10.1111/bph.14112. No abstract available.

6.

Updating the guidelines for data transparency in the British Journal of Pharmacology - data sharing and the use of scatter plots instead of bar charts.

George CH, Stanford SC, Alexander S, Cirino G, Docherty JR, Giembycz MA, Hoyer D, Insel PA, Izzo AA, Ji Y, MacEwan DJ, Sobey CG, Wonnacott S, Ahluwalia A.

Br J Pharmacol. 2017 Sep;174(17):2801-2804. doi: 10.1111/bph.13925. No abstract available.

7.

A new synthesis and preliminary evaluation of some analogues of mecamylamine - a compound with anti-addiction properties.

Mangan D, McNabola N, Clark EH, Bermudez I, Wonnacott S, Southern JM.

Org Biomol Chem. 2016 Nov 22;14(46):10787-10798.

PMID:
27812593
8.

Integration of inhibitory and excitatory effects of α7 nicotinic acetylcholine receptor activation in the prelimbic cortex regulates network activity and plasticity.

Udakis M, Wright VL, Wonnacott S, Bailey CP.

Neuropharmacology. 2016 Jun;105:618-629. doi: 10.1016/j.neuropharm.2016.02.028. Epub 2016 Feb 24.

9.

Experimental design and analysis and their reporting: new guidance for publication in BJP.

Curtis MJ, Bond RA, Spina D, Ahluwalia A, Alexander SP, Giembycz MA, Gilchrist A, Hoyer D, Insel PA, Izzo AA, Lawrence AJ, MacEwan DJ, Moon LD, Wonnacott S, Weston AH, McGrath JC.

Br J Pharmacol. 2015 Jul;172(14):3461-71. doi: 10.1111/bph.12856. No abstract available. Erratum in: Br J Pharmacol. 2015 Sep;172(18):4600.

10.

Sazetidine-A Activates and Desensitizes Native α7 Nicotinic Acetylcholine Receptors.

Brown JL, Wonnacott S.

Neurochem Res. 2015 Oct;40(10):2047-54. doi: 10.1007/s11064-014-1302-6. Epub 2014 Apr 12.

11.

The Concise Guide to PHARMACOLOGY 2013/14: overview.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, Belelli D, Bennett AJ, Birdsall NJ, Boison D, Bonner TI, Brailsford L, Bröer S, Brown P, Calo G, Carter WG, Catterall WA, Chan SL, Chao MV, Chiang N, Christopoulos A, Chun JJ, Cidlowski J, Clapham DE, Cockcroft S, Connor MA, Cox HM, Cuthbert A, Dautzenberg FM, Davenport AP, Dawson PA, Dent G, Dijksterhuis JP, Dollery CT, Dolphin AC, Donowitz M, Dubocovich ML, Eiden L, Eidne K, Evans BA, Fabbro D, Fahlke C, Farndale R, Fitzgerald GA, Fong TM, Fowler CJ, Fry JR, Funk CD, Futerman AH, Ganapathy V, Gaisnier B, Gershengorn MA, Goldin A, Goldman ID, Gundlach AL, Hagenbuch B, Hales TG, Hammond JR, Hamon M, Hancox JC, Hauger RL, Hay DL, Hobbs AJ, Hollenberg MD, Holliday ND, Hoyer D, Hynes NA, Inui KI, Ishii S, Jacobson KA, Jarvis GE, Jarvis MF, Jensen R, Jones CE, Jones RL, Kaibuchi K, Kanai Y, Kennedy C, Kerr ID, Khan AA, Klienz MJ, Kukkonen JP, Lapoint JY, Leurs R, Lingueglia E, Lippiat J, Lolait SJ, Lummis SC, Lynch JW, MacEwan D, Maguire JJ, Marshall IL, May JM, McArdle CA, McGrath JC, Michel MC, Millar NS, Miller LJ, Mitolo V, Monk PN, Moore PK, Moorhouse AJ, Mouillac B, Murphy PM, Neubig RR, Neumaier J, Niesler B, Obaidat A, Offermanns S, Ohlstein E, Panaro MA, Parsons S, Pwrtwee RG, Petersen J, Pin JP, Poyner DR, Prigent S, Prossnitz ER, Pyne NJ, Pyne S, Quigley JG, Ramachandran R, Richelson EL, Roberts RE, Roskoski R, Ross RA, Roth M, Rudnick G, Ryan RM, Said SI, Schild L, Sanger GJ, Scholich K, Schousboe A, Schulte G, Schulz S, Serhan CN, Sexton PM, Sibley DR, Siegel JM, Singh G, Sitsapesan R, Smart TG, Smith DM, Soga T, Stahl A, Stewart G, Stoddart LA, Summers RJ, Thorens B, Thwaites DT, Toll L, Traynor JR, Usdin TB, Vandenberg RJ, Villalon C, Vore M, Waldman SA, Ward DT, Willars GB, Wonnacott SJ, Wright E, Ye RD, Yonezawa A, Zimmermann M.

Br J Pharmacol. 2013 Dec;170(8):1449-58. doi: 10.1111/bph.12444.

12.

Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes.

Bennett HM, Lees K, Harper KM, Jones AK, Sattelle DB, Wonnacott S, Wolstenholme AJ.

J Neurochem. 2012 Dec;123(6):911-8. doi: 10.1111/jnc.12013. Epub 2012 Oct 10.

13.

Pharmacological differences between rat frontal cortex and hippocampus in the nicotinic modulation of noradrenaline release implicate distinct receptor subtypes.

Kennett A, Heal DJ, Wonnacott S.

Nicotine Tob Res. 2012 Nov;14(11):1339-45. doi: 10.1093/ntr/nts128. Epub 2012 May 21.

PMID:
22614547
14.

α6β2* and α4β2* nicotinic acetylcholine receptors as drug targets for Parkinson's disease.

Quik M, Wonnacott S.

Pharmacol Rev. 2011 Dec;63(4):938-66. doi: 10.1124/pr.110.003269. Review.

15.

Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans.

Glendinning SK, Buckingham SD, Sattelle DB, Wonnacott S, Wolstenholme AJ.

PLoS One. 2011;6(7):e22390. doi: 10.1371/journal.pone.0022390. Epub 2011 Jul 26.

16.

Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation.

Del Barrio L, Martín-de-Saavedra MD, Romero A, Parada E, Egea J, Avila J, McIntosh JM, Wonnacott S, López MG.

Toxicol Sci. 2011 Sep;123(1):193-205. doi: 10.1093/toxsci/kfr163. Epub 2011 Jun 29.

PMID:
21715663
17.

Molecular determinants for competitive inhibition of alpha4beta2 nicotinic acetylcholine receptors.

Iturriaga-Vásquez P, Carbone A, García-Beltrán O, Livingstone PD, Biggin PC, Cassels BK, Wonnacott S, Zapata-Torres G, Bermudez I.

Mol Pharmacol. 2010 Sep;78(3):366-75. doi: 10.1124/mol.110.065490. Epub 2010 Jun 14.

18.

In silico characterization of cytisinoids docked into an acetylcholine binding protein.

Abin-Carriquiry JA, Zunini MP, Cassels BK, Wonnacott S, Dajas F.

Bioorg Med Chem Lett. 2010 Jun 15;20(12):3683-7. doi: 10.1016/j.bmcl.2010.04.092. Epub 2010 May 6.

PMID:
20493692
19.

Oligomerisation differentially affects the acute and chronic actions of amyloid-beta in vitro.

Innocent N, Evans N, Hille C, Wonnacott S.

Neuropharmacology. 2010 Sep-Oct;59(4-5):343-52. doi: 10.1016/j.neuropharm.2010.04.003. Epub 2010 Apr 11.

PMID:
20388522
20.

Associated proteins: The universal toolbox controlling ligand gated ion channel function.

Araud T, Wonnacott S, Bertrand D.

Biochem Pharmacol. 2010 Jul 15;80(2):160-9. doi: 10.1016/j.bcp.2010.03.017. Epub 2010 Mar 25. Review.

PMID:
20346921
21.

Increase in locomotor activity after acute administration of the nicotinic receptor agonist 3-bromocytisine in rats.

Abin-Carriquiry JA, Urbanavicius J, Scorza C, Rebolledo-Fuentes M, Wonnacott S, Cassels BK, Dajas F.

Eur J Pharmacol. 2010 May 25;634(1-3):89-94. doi: 10.1016/j.ejphar.2010.02.030. Epub 2010 Feb 23.

PMID:
20184877
22.

Subtype-selective nicotinic agonists enhance olfactory working memory in normal rats: a novel use of the odour span task.

Rushforth SL, Allison C, Wonnacott S, Shoaib M.

Neurosci Lett. 2010 Mar 3;471(2):114-8. doi: 10.1016/j.neulet.2010.01.022. Epub 2010 Jan 18.

PMID:
20083163
23.

Glutamate-dopamine crosstalk in the rat prefrontal cortex is modulated by Alpha7 nicotinic receptors and potentiated by PNU-120596.

Livingstone PD, Dickinson JA, Srinivasan J, Kew JN, Wonnacott S.

J Mol Neurosci. 2010 Jan;40(1-2):172-6. doi: 10.1007/s12031-009-9232-5. Epub 2009 Aug 18.

PMID:
19688191
24.

Nicotinic acetylcholine receptors and the ascending dopamine pathways.

Livingstone PD, Wonnacott S.

Biochem Pharmacol. 2009 Oct 1;78(7):744-55. doi: 10.1016/j.bcp.2009.06.004. Epub 2009 Jun 11. Review.

PMID:
19523928
25.

alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex.

Livingstone PD, Srinivasan J, Kew JN, Dawson LA, Gotti C, Moretti M, Shoaib M, Wonnacott S.

Eur J Neurosci. 2009 Feb;29(3):539-50. doi: 10.1111/j.1460-9568.2009.06613.x. Epub 2009 Jan 28.

PMID:
19187266
26.

Molecular and cellular mechanisms of action of nicotine in the CNS.

Barik J, Wonnacott S.

Handb Exp Pharmacol. 2009;(192):173-207. doi: 10.1007/978-3-540-69248-5_7. Review.

PMID:
19184650
27.

Drug discrimination and neurochemical studies in alpha7 null mutant mice: tests for the role of nicotinic alpha7 receptors in dopamine release.

Quarta D, Naylor CG, Barik J, Fernandes C, Wonnacott S, Stolerman IP.

Psychopharmacology (Berl). 2009 Apr;203(2):399-410. doi: 10.1007/s00213-008-1281-x. Epub 2008 Aug 30.

PMID:
18758759
28.

Alpha-conotoxin Arenatus IB[V11L,V16D] [corrected] is a potent and selective antagonist at rat and human native alpha7 nicotinic acetylcholine receptors.

Innocent N, Livingstone PD, Hone A, Kimura A, Young T, Whiteaker P, McIntosh JM, Wonnacott S.

J Pharmacol Exp Ther. 2008 Nov;327(2):529-37. doi: 10.1124/jpet.108.142943. Epub 2008 Jul 29. Erratum in: J Pharmacol Exp Ther. 2008 Dec;327(3):1001.

29.

In vivo modulation of dopaminergic nigrostriatal pathways by cytisine derivatives: implications for Parkinson's Disease.

Abin-Carriquiry JA, Costa G, Urbanavicius J, Cassels BK, Rebolledo-Fuentes M, Wonnacott S, Dajas F.

Eur J Pharmacol. 2008 Jul 28;589(1-3):80-4. doi: 10.1016/j.ejphar.2008.05.013. Epub 2008 May 20.

PMID:
18589414
30.
31.

Smoking cessation 2008.

Wonnacott S.

IDrugs. 2008 Apr;11(4):256-9. No abstract available.

PMID:
18379957
32.

Differential activation of PKC delta in the substantia nigra of rats following striatal or nigral 6-hydroxydopamine lesions.

Hanrott K, Murray TK, Orfali Z, Ward M, Finlay C, O'Neill MJ, Wonnacott S.

Eur J Neurosci. 2008 Mar;27(5):1086-96. doi: 10.1111/j.1460-9568.2008.06097.x. Epub 2008 Feb 29.

PMID:
18312582
33.

Gates and filters: unveiling the physiological roles of nicotinic acetylcholine receptors in dopaminergic transmission.

Wonnacott S.

Br J Pharmacol. 2008 Mar;153 Suppl 1:S2-4. doi: 10.1038/sj.bjp.0707583. Epub 2008 Feb 4.

34.

Development of an anti-cotinine vaccine to potentiate nicotine-based smoking cessation strategies.

Oliver JL, Pashmi G, Barnett P, Mettens P, Biemans R, Monteyne P, Palmantier R, Gallagher T, Ramaya S, Wonnacott S.

Vaccine. 2007 Oct 16;25(42):7354-62. Epub 2007 Aug 30.

PMID:
17870213
35.

Comparison of the effects of bupropion and nicotine on locomotor activation and dopamine release in vivo.

Sidhpura N, Redfern P, Rowley H, Heal D, Wonnacott S.

Biochem Pharmacol. 2007 Oct 15;74(8):1292-8. Epub 2007 Jun 21.

PMID:
17678630
36.

Comparison of the effects of bupropion on nicotinic receptor-evoked [(3)H]dopamine release from rat striatal synaptosomes and slices.

Sidhpura N, Redfern P, Wonnacott S.

Eur J Pharmacol. 2007 Jul 12;567(1-2):102-9. Epub 2007 Apr 6.

PMID:
17477919
37.

Nicotine induces tyrosine hydroxylase plasticity in the neurodegenerating striatum.

Urbanavicius J, Ferreira M, Costa G, Abin-Carriquiry JA, Wonnacott S, Dajas F.

J Neurochem. 2007 Aug;102(3):723-30. Epub 2007 Apr 16.

38.

Differential effects of acute and chronic nicotine on Elk-1 in rat hippocampus.

Nuutinen S, Barik J, Jones IW, Wonnacott S.

Neuroreport. 2007 Jan 22;18(2):121-6.

PMID:
17301675
39.

Nicotinic receptors modulate transmitter cross talk in the CNS: nicotinic modulation of transmitters.

Wonnacott S, Barik J, Dickinson J, Jones IW.

J Mol Neurosci. 2006;30(1-2):137-40. Review.

PMID:
17192660
40.
41.
42.

The synthesis and nicotinic binding activity of (+/-)-epiquinamide and (+/-)-C(1)-epiepiquinamide.

Kanakubo A, Gray D, Innocent N, Wonnacott S, Gallagher T.

Bioorg Med Chem Lett. 2006 Sep 1;16(17):4648-51. Epub 2006 Jun 19.

PMID:
16784846
43.

C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists.

Abin-Carriquiry JA, Voutilainen MH, Barik J, Cassels BK, Iturriaga-Vásquez P, Bermudez I, Durand C, Dajas F, Wonnacott S.

Eur J Pharmacol. 2006 Apr 24;536(1-2):1-11. Epub 2006 Mar 6.

PMID:
16563372
44.

From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research.

Cassels BK, Bermúdez I, Dajas F, Abin-Carriquiry JA, Wonnacott S.

Drug Discov Today. 2005 Dec;10(23-24):1657-65. Review.

PMID:
16376826
45.

6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta.

Hanrott K, Gudmunsen L, O'Neill MJ, Wonnacott S.

J Biol Chem. 2006 Mar 3;281(9):5373-82. Epub 2005 Dec 16.

47.

Presynaptic alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate [3H]d-aspartate release from rat frontal cortex in vitro.

Rousseau SJ, Jones IW, Pullar IA, Wonnacott S.

Neuropharmacology. 2005 Jul;49(1):59-72. Epub 2005 Apr 21.

PMID:
15992581
48.

Why doesn't nicotinic ACh receptor immunoreactivity knock out?

Jones IW, Wonnacott S.

Trends Neurosci. 2005 Jul;28(7):343-5. Review.

PMID:
15979499
49.
50.

Nicotine: from molecular mechanisms to behaviour.

Wonnacott S, Sidhpura N, Balfour DJ.

Curr Opin Pharmacol. 2005 Feb;5(1):53-9. Review.

PMID:
15661626

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