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Preparation and In Vitro Evaluation of Neutron-Activated, Theranostic Samarium-153-Labeled Microspheres for Transarterial Radioembolization of Hepatocellular Carcinoma and Liver Metastasis.

Wong YH, Tan HY, Kasbollah A, Abdullah BJJ, Yeong CH.

Pharmaceutics. 2019 Nov 12;11(11). pii: E596. doi: 10.3390/pharmaceutics11110596.


Early and late risk of ischemic stroke after TAVR as compared to a nationwide background population.

De Backer O, Butt JH, Wong YH, Torp-Pedersen C, Terkelsen CJ, Nissen H, Fosbøl EL, Køber L, Søndergaard L.

Clin Res Cardiol. 2019 Oct 30. doi: 10.1007/s00392-019-01565-0. [Epub ahead of print]


GSKIP-Mediated Anchoring Increases Phosphorylation of Tau by PKA but Not by GSK3beta via cAMP/PKA/GSKIP/GSK3/Tau Axis Signaling in Cerebrospinal Fluid and iPS Cells in Alzheimer Disease.

Ko HJ, Chiou SJ, Wong YH, Wang YH, Lai Y, Chou CH, Wang C, Loh JK, Lieu AS, Cheng JT, Lin YT, Lu PJ, Fann MJ, Huang CF, Hong YR.

J Clin Med. 2019 Oct 21;8(10). pii: E1751. doi: 10.3390/jcm8101751.


Acetazolamide toxicity and dosing in dialysis patients.

Pak WLW, Chan KL, Chan Z, Law WP, Wong YH, Lam CK, Wong SHS.

Nephrology (Carlton). 2019 Sep 2. doi: 10.1111/nep.13654. [Epub ahead of print] No abstract available.


Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.

Zhong W, Pasunooti KK, Balamkundu S, Wong YH, Nah Q, Gadi V, Gnanakalai S, Chionh YH, McBee ME, Gopal P, Lim SH, Olivier N, Buurman ET, Dick T, Liu CF, Lescar J, Dedon PC.

J Med Chem. 2019 Sep 12;62(17):7788-7805. doi: 10.1021/acs.jmedchem.9b00582. Epub 2019 Aug 29.


Percutaneous retrieval of an embolized left atrial appendage closure device from the left atrium in a patient with previous MitraClips.

Chopra M, Wong YH, Søndergaard L, De Backer O.

BMC Cardiovasc Disord. 2019 Aug 14;19(1):196. doi: 10.1186/s12872-019-1170-8.


Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa.

Jaroensuk J, Wong YH, Zhong W, Liew CW, Maenpuen S, Sahili AE, Atichartpongkul S, Chionh YH, Nah Q, Thongdee N, McBee ME, Prestwich EG, DeMott MS, Chaiyen P, Mongkolsuk S, Dedon PC, Lescar J, Fuangthong M.

RNA. 2019 Nov;25(11):1481-1496. doi: 10.1261/rna.066746.118. Epub 2019 Aug 9.


GPCRs in Autocrine and Paracrine Regulations.

Tse LH, Wong YH.

Front Endocrinol (Lausanne). 2019 Jul 12;10:428. doi: 10.3389/fendo.2019.00428. eCollection 2019. Review.


Backbone resonance assignment for the full length tRNA-(N1G37) methyltransferase of Pseudomonas aeruginosa.

Li Y, Zhong W, Koay AZ, Ng HQ, Nah Q, Wong YH, Hill J, Lescar J, Dedon PC, Kang C.

Biomol NMR Assign. 2019 Oct;13(2):327-332. doi: 10.1007/s12104-019-09900-2. Epub 2019 Jun 7.


Propensity-Matched Comparison of Oral Anticoagulation Versus Antiplatelet Therapy After Left Atrial Appendage Closure With WATCHMAN.

Søndergaard L, Wong YH, Reddy VY, Boersma LVA, Bergmann MW, Doshi S, Kar S, Sievert H, Wehrenberg S, Stein K, Holmes DR Jr.

JACC Cardiovasc Interv. 2019 Jun 10;12(11):1055-1063. doi: 10.1016/j.jcin.2019.04.004.


Experimental assessment on feasibility of computed tomography-based thermometry for radiofrequency ablation on tissue equivalent polyacrylamide phantom.

Tan D, Mohamad NA, Wong YH, Yeong CH, Cheah PL, Sulaiman N, Abdullah BJJ, Fabell MK, Lim KS.

Int J Hyperthermia. 2019;36(1):554-561. doi: 10.1080/02656736.2019.1610800.


Structural determinants for peptide-bond formation by asparaginyl ligases.

Hemu X, El Sahili A, Hu S, Wong K, Chen Y, Wong YH, Zhang X, Serra A, Goh BC, Darwis DA, Chen MW, Sze SK, Liu CF, Lescar J, Tam JP.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11737-11746. doi: 10.1073/pnas.1818568116. Epub 2019 May 23.


Comparison assessment between SIM and MRM mode in the analysis of 3-MCPD ester, 2-MCPD ester and glycidyl ester.

Goh KM, Wong YH, Ang MY, Yeo SCM, Abas F, Lai OM, Tan CP.

Food Res Int. 2019 Jul;121:553-560. doi: 10.1016/j.foodres.2018.12.013. Epub 2018 Dec 12.


Personalized Three-Dimensional Printed Models in Congenital Heart Disease.

Sun Z, Lau I, Wong YH, Yeong CH.

J Clin Med. 2019 Apr 16;8(4). pii: E522. doi: 10.3390/jcm8040522. Review.


Rapid assessment of total MCPD esters in palm-based cooking oil using ATR-FTIR application and chemometric analysis.

Goh KM, Maulidiani M, Rudiyanto R, Wong YH, Ang MY, Yew WM, Abas F, Lai OM, Wang Y, Tan CP.

Talanta. 2019 Jun 1;198:215-223. doi: 10.1016/j.talanta.2019.01.111. Epub 2019 Jan 31.


Percutaneous management of an embolised MANTA large bore arteriotomy closure device.

Wong YH, De Backer O, Søndergaard L, Bieliauskas G.

EuroIntervention. 2019 May 20;15(1):74-75. doi: 10.4244/EIJ-D-18-01171. No abstract available.


Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01.

Gu Y, Wong YH, Liew CW, Chan CEZ, Murali TM, Yap J, Too CT, Purushotorman K, Hamidinia M, El Sahili A, Goh ATH, Teo RZC, Wood KJ, Hanson BJ, Gascoigne NRJ, Lescar J, Vathsala A, MacAry PA.

Nat Commun. 2019 Feb 21;10(1):893. doi: 10.1038/s41467-019-08790-1.


Quantitative and qualitative comparison of low- and high-cost 3D-printed heart models.

Lau I, Wong YH, Yeong CH, Abdul Aziz YF, Md Sari NA, Hashim SA, Sun Z.

Quant Imaging Med Surg. 2019 Jan;9(1):107-114. doi: 10.21037/qims.2019.01.02.


Patient-specific 3D printed model of biliary ducts with congenital cyst.

Allan A, Kealley C, Squelch A, Wong YH, Yeong CH, Sun Z.

Quant Imaging Med Surg. 2019 Jan;9(1):86-93. doi: 10.21037/qims.2018.12.01.


Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N1G37) Methyltransferase (TrmD) Inhibitors.

Zhong W, Koay A, Ngo A, Li Y, Nah Q, Wong YH, Chionh YH, Ng HQ, Koh-Stenta X, Poulsen A, Foo K, McBee M, Choong ML, El Sahili A, Kang C, Matter A, Lescar J, Hill J, Dedon P.

ACS Infect Dis. 2019 Mar 8;5(3):326-335. doi: 10.1021/acsinfecdis.8b00275. Epub 2019 Feb 4.


A Cross-National Comparison on Subjective Well-Being of Kindergarten Teachers: Hong Kong and Italy.

Benevene P, Wong YHP, Fiorilli C, De Stasio S.

Front Psychol. 2018 Dec 18;9:2626. doi: 10.3389/fpsyg.2018.02626. eCollection 2018.


Dual-Tracer PET/CT Differentiates 2 Types of Primary Cancers and Metastases in a Patient With Crossed Fused Renal Ectopia.

Ho CL, Chen S, Leung YL, Cheng KC, Wong YH.

Clin Nucl Med. 2019 Feb;44(2):157-158. doi: 10.1097/RLU.0000000000002390.


Implications of de novo mutations in guiding drug discovery: A study of four neuropsychiatric disorders.

So HC, Wong YH.

J Psychiatr Res. 2019 Mar;110:83-92. doi: 10.1016/j.jpsychires.2018.12.015. Epub 2018 Dec 14.


Differential associations of depression-related phenotypes with cardiometabolic risks: Polygenic analyses and exploring shared genetic variants and pathways.

Wong BC, Chau CK, Ao FK, Mo CH, Wong SY, Wong YH, So HC.

Depress Anxiety. 2019 Apr;36(4):330-344. doi: 10.1002/da.22861. Epub 2018 Dec 6.


An overview of current and emerging devices for percutaneous left atrial appendage closure.

Chow DHF, Wong YH, Park JW, Lam YY, De Potter T, Rodés-Cabau J, Asmarats L, Sandri M, Sideris E, McCaw T, Lee RJ, Sievert H, Søndergaard L, De Backer O.

Trends Cardiovasc Med. 2019 May;29(4):228-236. doi: 10.1016/j.tcm.2018.08.008. Epub 2018 Aug 30. Review.


Radioembolization with 90Y glass microspheres for hepatocellular carcinoma: significance of pretreatment 11C-acetate and 18F-FDG PET/CT and posttreatment 90Y PET/CT in individualized dose prescription.

Ho CL, Chen S, Cheung SK, Leung YL, Cheng KC, Wong KN, Wong YH, Leung TWT.

Eur J Nucl Med Mol Imaging. 2018 Nov;45(12):2110-2121. doi: 10.1007/s00259-018-4064-6. Epub 2018 Jun 11.


Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513.

Wong YH, Kumar A, Liew CW, Tharakaraman K, Srinivasaraghavan K, Sasisekharan R, Verma C, Lescar J.

Sci Rep. 2018 May 31;8(1):8449. doi: 10.1038/s41598-018-26800-y.


Exploring the regulatory role of nitric oxide (NO) and the NO-p38MAPK/cGMP pathway in larval settlement of the bryozoan Bugula neritina.

Yang XX, Wong YH, Zhang Y, Zhang G, Qian PY.

Biofouling. 2018 May;34(5):545-556. doi: 10.1080/08927014.2018.1470240. Epub 2018 May 29.


Small molecules as drugs to upregulate metastasis suppressors in cancer cells.

Wong KM, Song J, Saini V, Wong YH.

Curr Med Chem. 2018 May 21. doi: 10.2174/0929867325666180522090842. [Epub ahead of print]


HSP90 regulates larval settlement of the bryozoan Bugula neritina through the nitric oxide pathway.

Yang XX, Zhang Y, Wong YH, Qian PY.

J Exp Biol. 2018 Apr 23;221(Pt 8). pii: jeb167478. doi: 10.1242/jeb.167478.


Exploring coral microbiome assemblages in the South China Sea.

Cai L, Tian RM, Zhou G, Tong H, Wong YH, Zhang W, Chui APY, Xie JY, Qiu JW, Ang PO, Liu S, Huang H, Qian PY.

Sci Rep. 2018 Feb 5;8(1):2428. doi: 10.1038/s41598-018-20515-w.


Intravenous fluid selection rationales in acute clinical management.

Cheung WYS, Cheung WK, Lam CH, Chan YW, Chow HC, Cheng KL, Wong YH, Kam CW.

World J Emerg Med. 2018;9(1):13-19. doi: 10.5847/wjem.j.1920-8642.2018.01.002.


Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa.

Liu C, Liew CW, Wong YH, Tan ST, Poh WH, Manimekalai MSS, Rajan S, Xin L, Liang ZX, Grüber G, Rice SA, Lescar J.

J Bacteriol. 2018 Jan 10;200(3). pii: e00515-17. doi: 10.1128/JB.00515-17. Print 2018 Feb 1.


RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway.

Li Y, Song J, Tong Y, Chung SK, Wong YH.

Oncotarget. 2017 Jul 22;8(41):69945-69960. doi: 10.18632/oncotarget.19509. eCollection 2017 Sep 19.


Bisphosphonate use and the risk of breast cancer: a meta-analysis of observational studies.

Ou YJ, Chiu HF, Wong YH, Yang CC, Yang YH.

Pharmacoepidemiol Drug Saf. 2017 Oct;26(10):1286-1295. doi: 10.1002/pds.4302. Epub 2017 Aug 31. Review.


Metagenomic analysis reveals a green sulfur bacterium as a potential coral symbiont.

Cai L, Zhou G, Tian RM, Tong H, Zhang W, Sun J, Ding W, Wong YH, Xie JY, Qiu JW, Liu S, Huang H, Qian PY.

Sci Rep. 2017 Aug 24;7(1):9320. doi: 10.1038/s41598-017-09032-4.


Role of G Protein-Coupled Receptors in the Regulation of Structural Plasticity and Cognitive Function.

Leung CCY, Wong YH.

Molecules. 2017 Jul 24;22(7). pii: E1239. doi: 10.3390/molecules22071239. Review.


Are we making good use of our public resources? The false-positive rate of screening by fundus photography for diabetic macular oedema.

Wong RL, Tsang CW, Wong DS, McGhee S, Lam CH, Lian J, Lee JW, Lai JS, Chong V, Wong IY.

Hong Kong Med J. 2017 Aug;23(4):356-64. doi: 10.12809/hkmj166078. Epub 2017 Jul 7.


Structural Mimicry of the Dengue Virus Envelope Glycoprotein Revealed by the Crystallographic Study of an Idiotype-Anti-idiotype Fab Complex.

Wong YH, Goh BC, Lim SY, Teo EW, Lim APC, Dedon PC, Hanson BJ, MacAry PA, Lescar J.

J Virol. 2017 Aug 10;91(17). pii: e00406-17. doi: 10.1128/JVI.00406-17. Print 2017 Sep 1.


Optimal approach for complete liver tumor ablation using radiofrequency ablation: a simulation study.

Givehchi S, Wong YH, Yeong CH, Abdullah BJJ.

Minim Invasive Ther Allied Technol. 2018 Apr;27(2):81-89. doi: 10.1080/13645706.2017.1330757. Epub 2017 Jun 14.


Study of the inhibitory effects on TNF-α-induced NF-κB activation of IMD0354 analogs.

Li YR, Lin CC, Huang CY, Wong YH, Hsieh CH, Wu HW, Chen JJW, Wu YS.

Chem Biol Drug Des. 2017 Dec;90(6):1307-1311. doi: 10.1111/cbdd.13032. Epub 2017 Jul 11.


Hearing Loss amongst the Elderly in a Southeast Asian Population - A Community-based Study.

Lee JC, Danker AN, Wong YH, Lim MY.

Ann Acad Med Singapore. 2017 Apr;46(4):145-154.


Molecular adaptation in the world's deepest-living animal: Insights from transcriptome sequencing of the hadal amphipod Hirondellea gigas.

Lan Y, Sun J, Tian R, Bartlett DH, Li R, Wong YH, Zhang W, Qiu JW, Xu T, He LS, Tabata HG, Qian PY.

Mol Ecol. 2017 Jul;26(14):3732-3743. doi: 10.1111/mec.14149. Epub 2017 May 18.


B1, a novel HDAC inhibitor, induces apoptosis through the regulation of STAT3 and NF-κB.

Cheng MH, Wong YH, Chang CM, Yang CC, Chen SH, Yuan CL, Kuo HM, Yang CY, Chiu HF.

Int J Mol Med. 2017 May;39(5):1137-1148. doi: 10.3892/ijmm.2017.2946. Epub 2017 Apr 7.


Genome Reduction and Microbe-Host Interactions Drive Adaptation of a Sulfur-Oxidizing Bacterium Associated with a Cold Seep Sponge.

Tian RM, Zhang W, Cai L, Wong YH, Ding W, Qian PY.

mSystems. 2017 Mar 21;2(2). pii: e00184-16. doi: 10.1128/mSystems.00184-16. eCollection 2017 Mar-Apr.


Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients.

Thean LF, Wong YH, Lo M, Loi C, Chew MH, Tang CL, Cheah PY.

PLoS One. 2017 Mar 17;12(3):e0173772. doi: 10.1371/journal.pone.0173772. eCollection 2017.


Outcomes after oesophageal perforation: a retrospective cohort study of patients with different aetiologies.

Law TT, Chan JY, Chan DK, Tong D, Wong IY, Chan FS, Law S.

Hong Kong Med J. 2017 Jun;23(3):231-8. doi: 10.12809/hkmj164942. Epub 2017 Mar 10.


Engineering a Catalytically Efficient Recombinant Protein Ligase.

Yang R, Wong YH, Nguyen GKT, Tam JP, Lescar J, Wu B.

J Am Chem Soc. 2017 Apr 19;139(15):5351-5358. doi: 10.1021/jacs.6b12637. Epub 2017 Mar 1.


Screening for retinopathy of prematurity and treatment outcome in a tertiary hospital in Hong Kong.

Iu LP, Lai CH, Fan MC, Wong IY, Lai JS.

Hong Kong Med J. 2017 Feb;23(1):41-7. doi: 10.12809/hkmj154811. Epub 2016 Dec 30.

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