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Items: 1 to 50 of 450

1.

Biochemistry and use of soybean isoflavones in functional food development.

Hu C, Wong WT, Wu R, Lai WF.

Crit Rev Food Sci Nutr. 2019 Jul 5:1-15. doi: 10.1080/10408398.2019.1630598. [Epub ahead of print]

PMID:
31272191
2.

A multi-task deep learning model for the classification of Age-related Macular Degeneration.

Chen Q, Peng Y, Keenan T, Dharssi S, Agro N E, Wong WT, Chew EY, Lu Z.

AMIA Jt Summits Transl Sci Proc. 2019 May 6;2019:505-514. eCollection 2019.

3.

C3- and CR3-dependent microglial clearance protects photoreceptors in retinitis pigmentosa.

Silverman SM, Ma W, Wang X, Zhao L, Wong WT.

J Exp Med. 2019 Jun 17. pii: jem.20190009. doi: 10.1084/jem.20190009. [Epub ahead of print]

PMID:
31209071
4.

Catalytic asymmetric oxo-Diels-Alder reactions with chiral atropisomeric biphenyl diols.

Yeung CT, Chan WTK, Lo WS, Law GL, Wong WT.

Beilstein J Org Chem. 2019 Apr 18;15:955-962. doi: 10.3762/bjoc.15.92. eCollection 2019.

5.

Tackling Aging by Using miRNA as a Target and a Tool.

Lai WF, Lin M, Wong WT.

Trends Mol Med. 2019 May 21. pii: S1471-4914(19)30096-6. doi: 10.1016/j.molmed.2019.04.007. [Epub ahead of print] Review.

PMID:
31126873
6.

Breaking the 1,2-HOPO barrier with a cyclen backbone for more efficient sensitization of Eu(iii) luminescence and unprecedented two-photon excitation properties.

Dai L, Lo WS, Gu Y, Xiong Q, Wong KL, Kwok WM, Wong WT, Law GL.

Chem Sci. 2019 Mar 28;10(17):4550-4559. doi: 10.1039/c9sc00244h. eCollection 2019 May 7.

7.

Universal Strategy for HF-Free Facile and Rapid Synthesis of Two-dimensional MXenes as Multifunctional Energy Materials.

Pang SY, Wong YT, Yuan S, Liu Y, Tsang MK, Yang Z, Huang H, Wong WT, Hao J.

J Am Chem Soc. 2019 Jun 19;141(24):9610-9616. doi: 10.1021/jacs.9b02578. Epub 2019 Jun 4.

PMID:
31117483
8.

A biocompatible and easy-to-make polyelectrolyte dressing with tunable drug delivery properties for wound care.

Lai WF, Hu C, Deng G, Lui KH, Wang X, Tsoi TH, Wang S, Wong WT.

Int J Pharm. 2019 Jul 20;566:101-110. doi: 10.1016/j.ijpharm.2019.05.045. Epub 2019 May 16.

PMID:
31103820
9.

PREhabilitation for improving QUality of recovery after ELective cardiac surgery (PREQUEL) study: protocol of a randomised controlled trial.

Yau DKW, Wong MKH, Wong WT, Gin T, Underwood MJ, Joynt GM, Lee A.

BMJ Open. 2019 May 14;9(5):e027974. doi: 10.1136/bmjopen-2018-027974.

10.

Compound K inhibits priming and mitochondria-associated activating signals of NLRP3 inflammasome in renal tubulointerstitial lesions.

Hsu WH, Hua KF, Tuan LH, Tsai YL, Chu LJ, Lee YC, Wong WT, Lee SL, Lai JH, Chu CL, Ho LJ, Chiu HW, Hsu YJ, Chen CH, Ka SM, Chen A.

Nephrol Dial Transplant. 2019 May 7. pii: gfz073. doi: 10.1093/ndt/gfz073. [Epub ahead of print]

PMID:
31065699
11.

Synthesis of a Conformationally Stable Atropisomeric Pair of Biphenyl Scaffold Containing Additional Stereogenic Centers.

Yeung CT, Chan WTK, Lo WS, Law GL, Wong WT.

Molecules. 2019 Feb 12;24(3). pii: E643. doi: 10.3390/molecules24030643.

12.

Dealing With Death Taboo: Discussion of Do-Not-Resuscitate Directives With Chinese Patients With Noncancer Life-Limiting Illnesses.

Cheng HB, Shek PK, Man CW, Chan OM, Chan CH, Lai KM, Cheng SC, Fung KS, Lui WK, Lam C, Ng YK, Wong WT, Wong C.

Am J Hosp Palliat Care. 2019 Feb 11:1049909119828116. doi: 10.1177/1049909119828116. [Epub ahead of print]

PMID:
30744386
13.

LONGITUDINAL CHANGES IN EYES WITH HYDROXYCHLOROQUINE RETINAL TOXICITY.

Allahdina AM, Chen KG, Alvarez JA, Wong WT, Chew EY, Cukras CA.

Retina. 2019 Mar;39(3):473-484. doi: 10.1097/IAE.0000000000002437.

PMID:
30741731
14.

Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization.

Ma W, Silverman SM, Zhao L, Villasmil R, Campos MM, Amaral J, Wong WT.

Elife. 2019 Jan 22;8. pii: e42049. doi: 10.7554/eLife.42049.

15.

CHOROIDAL THICKNESS AND VASCULARITY VARY WITH DISEASE SEVERITY AND SUBRETINAL DRUSENOID DEPOSIT PRESENCE IN NONADVANCED AGE-RELATED MACULAR DEGENERATION.

Keenan TD, Klein B, Agrón E, Chew EY, Cukras CA, Wong WT.

Retina. 2019 Jan 3. doi: 10.1097/IAE.0000000000002434. [Epub ahead of print]

PMID:
30664125
16.

Preliminary Agreement on Tracking Sleep Between a Wrist-Worn Device Fitbit Alta and Consensus Sleep Diary.

Liu J, Wong WT, Zwetsloot IM, Hsu YC, Tsui KL.

Telemed J E Health. 2019 Jan 2. doi: 10.1089/tmj.2018.0202. [Epub ahead of print]

PMID:
30601109
17.

Oral Dextromethorphan for the Treatment of Diabetic Macular Edema: Results From a Phase I/II Clinical Study.

Valent DJ, Wong WT, Chew EY, Cukras CA.

Transl Vis Sci Technol. 2018 Dec 17;7(6):24. doi: 10.1167/tvst.7.6.24. eCollection 2018 Nov.

18.

Ergosterol peroxide from marine fungus Phoma sp. induces ROS-dependent apoptosis and autophagy in human lung adenocarcinoma cells.

Wu HY, Yang FL, Li LH, Rao YK, Ju TC, Wong WT, Hsieh CY, Pivkin MV, Hua KF, Wu SH.

Sci Rep. 2018 Dec 18;8(1):17956. doi: 10.1038/s41598-018-36411-2.

19.

Quantification of Beat-To-Beat Variability of Action Potential Durations in Langendorff-Perfused Mouse Hearts.

Tse G, Du Y, Hao G, Li KHC, Chan FYW, Liu T, Li G, Bazoukis G, Letsas KP, Wu WKK, Cheng SH, Wong WT.

Front Physiol. 2018 Nov 27;9:1578. doi: 10.3389/fphys.2018.01578. eCollection 2018.

20.

Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ.

Cheang WS, Wong WT, Wang L, Cheng CK, Lau CW, Ma RCW, Xu A, Wang N, Huang Y, Tian XY.

Pharmacol Res. 2019 Jan;139:384-394. doi: 10.1016/j.phrs.2018.11.041. Epub 2018 Nov 29.

PMID:
30503839
21.

DeepSeeNet: A Deep Learning Model for Automated Classification of Patient-based Age-related Macular Degeneration Severity from Color Fundus Photographs.

Peng Y, Dharssi S, Chen Q, Keenan TD, Agrón E, Wong WT, Chew EY, Lu Z.

Ophthalmology. 2019 Apr;126(4):565-575. doi: 10.1016/j.ophtha.2018.11.015. Epub 2018 Nov 22.

PMID:
30471319
22.

Professional burnout among physicians and nurses in Asian intensive care units: a multinational survey.

See KC, Zhao MY, Nakataki E, Chittawatanarat K, Fang WF, Faruq MO, Wahjuprajitno B, Arabi YM, Wong WT, Divatia JV, Palo JE, Shrestha BR, Nafees KMK, Binh NG, Al Rahma HN, Detleuxay K, Ong V, Phua J; SABA Study Investigators and the Asian Critical Care Clinical Trials Group.

Intensive Care Med. 2018 Dec;44(12):2079-2090. doi: 10.1007/s00134-018-5432-1. Epub 2018 Nov 16.

PMID:
30446797
23.

The TRPC5 channel regulates angiogenesis and promotes recovery from ischemic injury in mice.

Zhu Y, Gao M, Zhou T, Xie M, Mao A, Feng L, Yao X, Wong WT, Ma X.

J Biol Chem. 2019 Jan 4;294(1):28-37. doi: 10.1074/jbc.RA118.005392. Epub 2018 Nov 9.

PMID:
30413532
24.

Higher Dispersion Measures of Conduction and Repolarization in Type 1 Compared to Non-type 1 Brugada Syndrome Patients: An Electrocardiographic Study From a Single Center.

Tse G, Li KHC, Li G, Liu T, Bazoukis G, Wong WT, Chan MTV, Wong MCS, Xia Y, Letsas KP, Chan GCP, Chan YS, Wu WKK.

Front Cardiovasc Med. 2018 Oct 4;5:132. doi: 10.3389/fcvm.2018.00132. eCollection 2018.

25.

Comparison of high-flow nasal cannula versus oxygen face mask for environmental bacterial contamination in critically ill pneumonia patients: a randomized controlled crossover trial.

Leung CCH, Joynt GM, Gomersall CD, Wong WT, Lee A, Ling L, Chan PKS, Lui PCW, Tsoi PCY, Ling CM, Hui M.

J Hosp Infect. 2019 Jan;101(1):84-87. doi: 10.1016/j.jhin.2018.10.007. Epub 2018 Oct 15.

26.

Patent foramen ovale closure versus medical therapy for stroke prevention: A systematic review and meta-analysis of randomized controlled trials.

Lai JCL, Tse G, Wu WKK, Gong M, Bazoukis G, Wong WT, Wong SH, Lampropoulos K, Baranchuk A, Tse LA, Xia Y, Li G, Wong MCS, Chan YS, Mu N, Dong M, Liu T; International Health Informatics Study (IHIS) Network.

Version 2. F1000Res. 2017 Dec 27 [revised 2018 Jan 1];6:2178. doi: 10.12688/f1000research.13444.2. eCollection 2017.

27.

Longitudinal Study of Dark Adaptation as a Functional Outcome Measure for Age-Related Macular Degeneration.

Chen KG, Alvarez JA, Yazdanie M, Papudesu C, Wong WT, Wiley HE, Keenan TD, Chew EY, Ferris FL 3rd, Cukras CA.

Ophthalmology. 2019 Jun;126(6):856-865. doi: 10.1016/j.ophtha.2018.09.039. Epub 2018 Sep 29.

PMID:
30278196
28.

What lies beneath? Experiencing emotions and caring in oncology.

Wong WT, Broom A, Kirby E, Lwin Z.

Health (London). 2018 Sep 24:1363459318800168. doi: 10.1177/1363459318800168. [Epub ahead of print]

PMID:
30244612
29.

Repositioning of the β-Blocker Carvedilol as a Novel Autophagy Inducer That Inhibits the NLRP3 Inflammasome.

Wong WT, Li LH, Rao YK, Yang SP, Cheng SM, Lin WY, Cheng CC, Chen A, Hua KF.

Front Immunol. 2018 Aug 22;9:1920. doi: 10.3389/fimmu.2018.01920. eCollection 2018.

30.

Uncoupling Protein 2 in Cardiovascular Health and Disease.

Tian XY, Ma S, Tse G, Wong WT, Huang Y.

Front Physiol. 2018 Aug 2;9:1060. doi: 10.3389/fphys.2018.01060. eCollection 2018. Review.

31.

Argininosuccinate Lyase Deficiency Causes an Endothelial-Dependent Form of Hypertension.

Kho J, Tian X, Wong WT, Bertin T, Jiang MM, Chen S, Jin Z, Shchelochkov OA, Burrage LC, Reddy AK, Jiang H, Abo-Zahrah R, Ma S, Zhang P, Bissig KD, Kim JJ, Devaraj S, Rodney GG, Erez A, Bryan NS, Nagamani SCS, Lee BH.

Am J Hum Genet. 2018 Aug 2;103(2):276-287. doi: 10.1016/j.ajhg.2018.07.008.

32.

Palladium-Catalyzed N-Arylation of Sulfoximines with Aryl Sulfonates.

Yang Q, Choy PY, Zhao Q, Leung MP, Chan HS, So CM, Wong WT, Kwong FY.

J Org Chem. 2018 Sep 21;83(18):11369-11376. doi: 10.1021/acs.joc.8b01599. Epub 2018 Aug 13.

PMID:
30062889
33.

Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.

Keenan TD, Agrón E, Domalpally A, Clemons TE, van Asten F, Wong WT, Danis RG, Sadda S, Rosenfeld PJ, Klein ML, Ratnapriya R, Swaroop A, Ferris FL 3rd, Chew EY; AREDS2 Research Group.

Ophthalmology. 2018 Dec;125(12):1913-1928. doi: 10.1016/j.ophtha.2018.05.028. Epub 2018 Jul 27.

PMID:
30060980
34.

Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models.

Chen ZS, Li L, Peng S, Chen FM, Zhang Q, An Y, Lin X, Li W, Koon AC, Chan TF, Lau KF, Ngo JCK, Wong WT, Kwan KM, Chan HYE.

EMBO Rep. 2018 Sep;19(9). pii: e45409. doi: 10.15252/embr.201745409. Epub 2018 Jul 19.

PMID:
30026307
35.

Microglia in the Retina: Roles in Development, Maturity, and Disease.

Silverman SM, Wong WT.

Annu Rev Vis Sci. 2018 Sep 15;4:45-77. doi: 10.1146/annurev-vision-091517-034425. Epub 2018 May 31. Review.

PMID:
29852094
36.

TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes.

Li Z, Meng Z, Lu J, Chen FM, Wong WT, Tse G, Zheng C, Keung W, Tse K, Li RA, Jiang L, Yao X.

J Mol Cell Cardiol. 2018 Jul;120:1-11. doi: 10.1016/j.yjmcc.2018.05.008. Epub 2018 May 16.

PMID:
29758225
37.

Repopulating retinal microglia restore endogenous organization and function under CX3CL1-CX3CR1 regulation.

Zhang Y, Zhao L, Wang X, Ma W, Lazere A, Qian HH, Zhang J, Abu-Asab M, Fariss RN, Roger JE, Wong WT.

Sci Adv. 2018 Mar 21;4(3):eaap8492. doi: 10.1126/sciadv.aap8492. eCollection 2018 Mar.

38.

Multispectral Photoacoustic Imaging of Tumor Protease Activity with a Gold Nanocage-Based Activatable Probe.

Liu C, Li S, Gu Y, Xiong H, Wong WT, Sun L.

Mol Imaging Biol. 2018 Dec;20(6):919-929. doi: 10.1007/s11307-018-1203-1.

PMID:
29736563
39.

Evaluation of Meropenem Pharmacokinetics in an Experimental Acute Respiratory Distress Syndrome (ARDS) Model during Extracorporeal Membrane Oxygenation (ECMO) by Using a PenP β-Lactamase Biosensor.

Andresen M, Araos J, Wong KY, Leung YC, So LY, Wong WT, Cabrera S, Silva C, Alegria L, Bruhn A, Soto D.

Sensors (Basel). 2018 May 4;18(5). pii: E1424. doi: 10.3390/s18051424.

40.

Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) in clinical practice.

Li KHC, Bazoukis G, Liu T, Li G, Wu WKK, Wong SH, Wong WT, Chan YS, Wong MCS, Wassilew K, Vassiliou VS, Tse G.

J Arrhythm. 2017 Dec 21;34(1):11-22. doi: 10.1002/joa3.12021. eCollection 2018 Feb. Review.

41.

Genotype-guided warfarin dosing vs. conventional dosing strategies: a systematic review and meta-analysis of randomized controlled trials.

Tse G, Gong M, Li G, Wong SH, Wu WKK, Wong WT, Roever L, Lee APW, Lip GYH, Wong MCS, Liu T; International Health Informatics Study (IHIS) Network.

Br J Clin Pharmacol. 2018 Sep;84(9):1868-1882. doi: 10.1111/bcp.13621. Epub 2018 Jun 21.

PMID:
29704269
42.

Optical Coherence Tomography Minimum Intensity as an Objective Measure for the Detection of Hydroxychloroquine Toxicity.

Allahdina AM, Stetson PF, Vitale S, Wong WT, Chew EY, Ferris FL III, Sieving PA, Cukras C.

Invest Ophthalmol Vis Sci. 2018 Apr 1;59(5):1953-1963. doi: 10.1167/iovs.17-22668.

43.

Scalable synthesis enabling multilevel bio-evaluations of natural products for discovery of lead compounds.

Zhu L, Ma W, Zhang M, Lee MM, Wong WY, Chan BD, Yang Q, Wong WT, Tai WC, Lee CS.

Nat Commun. 2018 Mar 29;9(1):1283. doi: 10.1038/s41467-018-03546-9.

44.

Design of Polymeric Gene Carriers for Effective Intracellular Delivery.

Lai WF, Wong WT.

Trends Biotechnol. 2018 Jul;36(7):713-728. doi: 10.1016/j.tibtech.2018.02.006. Epub 2018 Mar 7. Review.

PMID:
29525137
45.

Light-Dependent OCT Structure Changes in Photoreceptor Degenerative rd 10 Mouse Retina.

Li Y, Zhang Y, Chen S, Vernon G, Wong WT, Qian H.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):1084-1094. doi: 10.1167/iovs.17-23011.

46.

Fibroblast growth factor 21 in cardio-metabolic disorders: a systematic review and meta-analysis.

Lakhani I, Gong M, Wong WT, Bazoukis G, Lampropoulos K, Wong SH, Wu WKK, Wong MCS, Ong KL, Liu T, Tse G; International Health Informatics Study (IHIS) Network.

Metabolism. 2018 Jun;83:11-17. doi: 10.1016/j.metabol.2018.01.017. Epub 2018 Feb 2.

PMID:
29410351
47.

Efficient expression and isolation of recombinant human interleukin-11 (rhIL-11) in Pichia pastoris.

Yu KM, Yiu-Nam Lau J, Fok M, Yeung YK, Fok SP, Shek F, Wong WT, Choo QL.

Protein Expr Purif. 2018 Jun;146:69-77. doi: 10.1016/j.pep.2018.01.012. Epub 2018 Feb 3.

PMID:
29408294
48.

Preclinical evaluation of the mono-PEGylated recombinant human interleukin-11 in cynomolgus monkeys.

Yu KM, Lau JY, Fok M, Yeung YK, Fok SP, Zhang S, Ye P, Zhang K, Li X, Li J, Xu Q, Wong WT, Choo QL.

Toxicol Appl Pharmacol. 2018 Mar 1;342:39-49. doi: 10.1016/j.taap.2018.01.016. Epub 2018 Feb 2.

PMID:
29407773
49.

Cancer antigen-125 and risk of atrial fibrillation: a systematic review and meta-analysis.

Cheung A, Gong M, Bellanti R, Ali-Hasan-Al-Saegh S, Li G, Roig E, Núñez J, Stamos TD, Yilmaz MB, Hakki K, Wu WKK, Wong SH, Wong WT, Bazoukis G, Lampropoulos K, Tse LA, Zhao J, Lip GYH, Baranchuk A, Wong MCS, Liu T, Tse G.

Heart Asia. 2018 Jan 7;10(1):e010970. doi: 10.1136/heartasia-2017-010970. eCollection 2018.

50.

Clostridium difficile toxin B induces autophagic cell death in colonocytes.

Chan H, Zhao S, Zhang L, Ho J, Leung CCH, Wong WT, Tian Y, Liu X, Kwong TNY, Chan RCY, Yu SSB, Wang MHT, Tse G, Wong SH, Chan MTV, Wu WKK.

J Cell Mol Med. 2018 Apr;22(4):2469-2477. doi: 10.1111/jcmm.13555. Epub 2018 Jan 31.

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