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Cilia-Associated Oxysterols Activate Smoothened.

Raleigh DR, Sever N, Choksi PK, Sigg MA, Hines KM, Thompson BM, Elnatan D, Jaishankar P, Bisignano P, Garcia-Gonzalo FR, Krup AL, Eberl M, Byrne EFX, Siebold C, Wong SY, Renslo AR, Grabe M, McDonald JG, Xu L, Beachy PA, Reiter JF.

Mol Cell. 2018 Oct 18;72(2):316-327.e5. doi: 10.1016/j.molcel.2018.08.034.


Evaluation of Carbazeran 4-Oxidation and O6-Benzylguanine 8-Oxidation as Catalytic Markers of Human Aldehyde Oxidase: Impact of Cytosolic Contamination of Liver Microsomes.

Xie J, Saburulla NF, Chen S, Wong SY, Yap ZP, Zhang LH, Lau AJ.

Drug Metab Dispos. 2018 Oct 18. pii: dmd.118.082099. doi: 10.1124/dmd.118.082099. [Epub ahead of print]


The adoption of hypertension reference framework: An investigation among primary care physicians of Hong Kong.

Fang Y, Wang HHX, Liang M, Yeung MS, Leung C, Chan CH, Cheung W, Huang JLW, Huang J, Sit RWS, Wong SYS, Wong MCS.

PLoS One. 2018 Oct 9;13(10):e0205529. doi: 10.1371/journal.pone.0205529. eCollection 2018.


Iridium(iii) complexes as reaction based chemosensors for medical diagnostics.

Ma DL, Ng HP, Wong SY, Vellaisamy K, Wu KJ, Leung CH.

Dalton Trans. 2018 Oct 1. doi: 10.1039/c8dt03492c. [Epub ahead of print]


There was collusion: Microbes in inflammatory bowel disease.

Wong SY, Cadwell K.

PLoS Pathog. 2018 Sep 20;14(9):e1007215. doi: 10.1371/journal.ppat.1007215. eCollection 2018 Sep. No abstract available.


Development of adaptable pandemic simulation models.

Tsui KL, Wong SY, Wu JT, Chow CB, Goldsman DM, Nizam A.

Hong Kong Med J. 2018 Oct;24 Suppl 6(5):23-25. No abstract available.


The independent role of deprivation in abdominal obesity beyond income poverty. A population-based household survey in Chinese adults.

Chung GK, Chung RY, Chan DC, Lai FT, Wong H, Lau MK, Wong SY, Yeoh EK.

J Public Health (Oxf). 2018 Sep 12. doi: 10.1093/pubmed/fdy161. [Epub ahead of print]


Retraction notice to "The effectiveness of group-based behavioral activation in the treatment of depression: an updated meta-analysis of randomized controlled trial" [JAD 208 (2017) 345-l354].

Chan ATY, Sun GYY, Tam WWS, Tsoi KKF, Wong SYS.

J Affect Disord. 2018 Dec 1;241:634. doi: 10.1016/j.jad.2018.07.084. No abstract available.


Nurse-led repeat prescription for patients with controlled hypertension: a randomised controlled trial.

Yip BH, Lee EK, Sit RW, Wong C, Li X, Wong EL, Wong MC, Chung RY, Chung VC, Kung K, Wong SY.

Hong Kong Med J. 2018 Aug;24 Suppl 4(4):4-7. No abstract available.


Loss of Gata6 causes dilation of the hair follicle canal and sebaceous duct.

Swanson JB, Vagnozzi AN, Veniaminova NA, Wong SY.

Exp Dermatol. 2018 Jul 22. doi: 10.1111/exd.13757. [Epub ahead of print]


B Cell Defects Observed in Nod2 Knockout Mice Are a Consequence of a Dock2 Mutation Frequently Found in Inbred Strains.

Wong SY, Coffre M, Ramanan D, Hines MJ, Gomez LE, Peters LA, Schadt EE, Koralov SB, Cadwell K.

J Immunol. 2018 Sep 1;201(5):1442-1451. doi: 10.4049/jimmunol.1800014. Epub 2018 Jul 16.


Nurse-led hypertension management was well accepted and non-inferior to physician consultation in a Chinese population: a randomized controlled trial.

Yip BHK, Lee EKP, Sit RWS, Wong C, Li X, Wong ELY, Wong MCS, Chung RYN, Chung VCH, Kung K, Wong SYS.

Sci Rep. 2018 Jul 9;8(1):10302. doi: 10.1038/s41598-018-28721-2.


Geriatric syndromes, multimorbidity, and disability overlap and increase healthcare use among older Chinese.

Cheung JTK, Yu R, Wu Z, Wong SYS, Woo J.

BMC Geriatr. 2018 Jun 25;18(1):147. doi: 10.1186/s12877-018-0840-1.


Chinese Women's Drinking Patterns Before and After the Hong Kong Alcohol Policy Changes.

Wong EC, Kim JH, Goggins WB, Lau J, Wong SYS, Griffiths SM.

Alcohol Alcohol. 2018 Jul 1;53(4):477-486. doi: 10.1093/alcalc/agy010.


Electroacupuncture and wrist splinting for carpal tunnel syndrome: a randomised trial.

Chung VC, Wong SY, Kung K, Zee CY, Leung WN, Chong KC, Wong M, Wong C, Griffiths SM.

Hong Kong Med J. 2017 Jun;23 Suppl 2(3):28-31. No abstract available.


Trial Protocol: The use of mindfulness-based intervention for improving bracing compliance for adolescent idiopathic scoliosis patients: protocol for a randomised, controlled trial.

Yip BHK, Li X, Leung CHY, Gao T, Chung VCH, Yu FWP, Lam TP, Cheng JCY, Wong SYS.

J Physiother. 2018 Jul;64(3):193. doi: 10.1016/j.jphys.2018.02.019. Epub 2018 Jun 12.


Effects of nut consumption on selected inflammatory markers: a systematic review and meta-analysis of randomized controlled trials.

Xiao Y, Xia J, Ke Y, Cheng J, Yuan J, Wu S, Lv Z, Huang S, Kim JH, Wong SY, Yeoh EK, Colditz GA, Su X.

Nutrition. 2018 Oct;54:129-143. doi: 10.1016/j.nut.2018.02.017. Epub 2018 Mar 27. Review.


Efficacy of intra-articular hypertonic dextrose prolotherapy versus normal saline for knee osteoarthritis: a protocol for a triple-blinded randomized controlled trial.

Sit RWS, Wu RWK, Reeves KD, Rabago D, Chan DCC, Yip BHK, Chung VCH, Wong SYS.

BMC Complement Altern Med. 2018 May 15;18(1):157. doi: 10.1186/s12906-018-2226-5.


Night shift work exposure profile and obesity: Baseline results from a Chinese night shift worker cohort.

Sun M, Feng W, Wang F, Zhang L, Wu Z, Li Z, Zhang B, He Y, Xie S, Li M, Fok JPC, Tse G, Wong MCS, Tang JL, Wong SYS, Vlaanderen J, Evans G, Vermeulen R, Tse LA.

PLoS One. 2018 May 15;13(5):e0196989. doi: 10.1371/journal.pone.0196989. eCollection 2018.


Deprivation is associated with worse physical and mental health beyond income poverty: a population-based household survey among Chinese adults.

Chung RY, Chung GK, Gordon D, Wong SY, Chan D, Lau MK, Tang VM, Wong H.

Qual Life Res. 2018 May 14. doi: 10.1007/s11136-018-1863-y. [Epub ahead of print]


Prevention of post-sphincterotomy bleeding by proton pump inhibitor: A randomized controlled trial.

Leung WK, But DY, Wong SY, Tong TS, Liu KS, Cheung KS, Tsang SH, Chok KS, Poon RT, Hung IF.

J Dig Dis. 2018 Jun;19(6):369-376. doi: 10.1111/1751-2980.12604. Epub 2018 May 24.


Monotherapy Is Good Enough for Patients With Mild-to-Moderate Alzheimer's Disease: A Network Meta-Analysis of 76 Randomized Controlled Trials.

Tsoi KKF, Chan JYC, Chan FCH, Hirai HW, Kwok TCY, Wong SYS.

Clin Pharmacol Ther. 2018 May 1. doi: 10.1002/cpt.1104. [Epub ahead of print]


Collaborate across silos: Perceived barriers to integration of care for the elderly from the perspectives of service providers.

Lau JY, Wong EL, Chung RY, Law SCK, Threapleton D, Kiang N, Chau P, Wong SYS, Woo J, Yeoh EK.

Int J Health Plann Manage. 2018 Apr 27. doi: 10.1002/hpm.2534. [Epub ahead of print]


Mindfulness-Based Stress Reduction (MBSR) or Psychoeducation for the Reduction of Menopausal Symptoms: A Randomized, Controlled Clinical Trial.

Wong C, Yip BH, Gao T, Lam KYY, Woo DMS, Yip ALK, Chin CY, Tang WPY, Choy MMT, Tsang KWK, Ho SC, Ma HSW, Wong SYS.

Sci Rep. 2018 Apr 26;8(1):6609. doi: 10.1038/s41598-018-24945-4.


Meaning and its association with happiness, health and healthcare utilization: A cross-sectional study.

Zhang D, Chan DC, Niu L, Liu H, Zou D, Chan AT, Gao TT, Zhong B, Sit RW, Wong SY.

J Affect Disord. 2018 Feb;227:795-802. doi: 10.1016/j.jad.2017.11.082. Epub 2017 Nov 16.


Vitamin D non-sufficiency is prevalent in children with chronic liver disease in a tropical country.

Lee WS, Jalaludin MY, Wong SY, Ong SY, Foo HW, Ng RT.

Pediatr Neonatol. 2018 Apr 5. pii: S1875-9572(17)30332-7. doi: 10.1016/j.pedneo.2018.03.011. [Epub ahead of print]


Mapping the contribution and strategic distribution patterns of neuroimaging features of small vessel disease in poststroke cognitive impairment.

Shi L, Zhao L, Yeung FK, Wong SY, Chan RKT, Tse MF, Chan SC, Kwong YC, Li KC, Liu K, Abrigo JM, Lau AYL, Wong A, Lam BYK, Leung TWH, Fu J, Chu WCW, Mok VCT.

J Neurol Neurosurg Psychiatry. 2018 Sep;89(9):918-926. doi: 10.1136/jnnp-2017-317817. Epub 2018 Apr 17.


Utilization of psychiatric care and antidepressants among people with different severity of depression: a population-based cohort study in Stockholm, Sweden.

Sun Y, Möller J, Lundin A, Wong SYS, Yip BHK, Forsell Y.

Soc Psychiatry Psychiatr Epidemiol. 2018 Jun;53(6):607-615. doi: 10.1007/s00127-018-1515-0. Epub 2018 Apr 12.


Electroacupuncture plus standard of care for managing refractory functional dyspepsia: protocol of a pragmatic trial with economic evaluation.

Chung VCH, Wong CHL, Ching JYL, Sun WZ, Ju YL, Hung SS, Lin WL, Leung KC, Wong SYS, Wu JCY.

BMJ Open. 2018 Mar 27;8(3):e018430. doi: 10.1136/bmjopen-2017-018430.


Clinical effectiveness of patella mobilisation therapy versus a waiting list control for knee osteoarthritis: a protocol for a pragmatic randomised clinical trial.

Sit RWS, Chan KKW, Yip BHK, Zhang DD, Reeves KD, Chan YH, Chung VCH, Wong SYS.

BMJ Open. 2018 Mar 14;8(3):e019103. doi: 10.1136/bmjopen-2017-019103.


Quality indicators in pediatric colonoscopy in a low-volume center: Implications for training.

Lee WS, Tee CW, Koay ZL, Wong TS, Zahraq F, Foo HW, Ong SY, Wong SY, Ng RT.

World J Gastroenterol. 2018 Mar 7;24(9):1013-1021. doi: 10.3748/wjg.v24.i9.1013.


Treating Subthreshold Depression in Primary Care: A Randomized Controlled Trial of Behavioral Activation With Mindfulness.

Wong SYS, Sun YY, Chan ATY, Leung MKW, Chao DVK, Li CCK, Chan KKH, Tang WK, Mazzucchelli T, Au AML, Yip BHK.

Ann Fam Med. 2018 Mar;16(2):111-119. doi: 10.1370/afm.2206.


Hepatopulmonary Syndrome and Portopulmonary Hypertension in Children: Recent Advances in Diagnosis and Management.

Lee WS, Wong SY, Ivy DD, Sokol RJ.

J Pediatr. 2018 May;196:14-21.e1. doi: 10.1016/j.jpeds.2017.12.068. Epub 2018 Mar 5. No abstract available.


Correction: Antibiotic resistance rates and physician antibiotic prescription patterns of uncomplicated urinary tract infections in southern Chinese primary care.

Wong CKM, Kung K, Au-Doung PLW, Ip M, Lee N, Fung A, Wong SYS.

PLoS One. 2018 Feb 23;13(2):e0192466. doi: 10.1371/journal.pone.0192466. eCollection 2018.


Identification of Galeterone and Abiraterone as Inhibitors of Dehydroepiandrosterone Sulfonation Catalyzed by Human Hepatic Cytosol, SULT2A1, SULT2B1b, and SULT1E1.

Yip CKY, Bansal S, Wong SY, Lau AJ.

Drug Metab Dispos. 2018 Apr;46(4):470-482. doi: 10.1124/dmd.117.078980. Epub 2018 Feb 7.


Receptive Music Therapy Is More Effective than Interactive Music Therapy to Relieve Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-Analysis.

Tsoi KKF, Chan JYC, Ng YM, Lee MMY, Kwok TCY, Wong SYS.

J Am Med Dir Assoc. 2018 Jul;19(7):568-576.e3. doi: 10.1016/j.jamda.2017.12.009. Epub 2018 Feb 1. Review.


Tumor Architecture and Notch Signaling Modulate Drug Response in Basal Cell Carcinoma.

Eberl M, Mangelberger D, Swanson JB, Verhaegen ME, Harms PW, Frohm ML, Dlugosz AA, Wong SY.

Cancer Cell. 2018 Feb 12;33(2):229-243.e4. doi: 10.1016/j.ccell.2017.12.015. Epub 2018 Jan 27.


Identification of a rhodium(iii) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells.

Yang GJ, Zhong HJ, Ko CN, Wong SY, Vellaisamy K, Ye M, Ma DL, Leung CH.

Chem Commun (Camb). 2018 Mar 6;54(20):2463-2466. doi: 10.1039/c7cc09384e.


Mutations in Hnrnpa1 cause congenital heart defects.

Yu Z, Tang PL, Wang J, Bao S, Shieh JT, Leung AW, Zhang Z, Gao F, Wong SY, Hui AL, Gao Y, Dung N, Zhang ZG, Fan Y, Zhou X, Zhang Y, Wong DS, Sham PC, Azhar A, Kwok PY, Tam PP, Lian Q, Cheah KS, Wang B, Song YQ.

JCI Insight. 2018 Jan 25;3(2). pii: 98555. doi: 10.1172/jci.insight.98555. [Epub ahead of print]


Effectiveness of smartphone technologies on glycaemic control in patients with type 2 diabetes: systematic review with meta-analysis of 17 trials.

Wu IXY, Kee JCY, Threapleton DE, Ma RCW, Lam VCK, Lee EKP, Wong SYS, Chung VCH.

Obes Rev. 2018 Jun;19(6):825-838. doi: 10.1111/obr.12669. Epub 2018 Jan 17. Review.


Efficacy and tolerability of trastuzumab emtansine in advanced human epidermal growth factor receptor 2-positive breast cancer.

Yeo W, Luk MY, Soong IS, Yuen TY, Ng TY, Mo FK, Chan K, Wong SY, Tsang J, Leung C, Suen JJ, Ngan RK.

Hong Kong Med J. 2018 Feb;24(1):56-62. doi: 10.12809/hkmj176808. Epub 2018 Jan 12.


Nurse experiences of medication administration to people with swallowing difficulties living in aged care facilities: a systematic review of qualitative evidence.

Forough AS, Wong SYM, Lau ETL, Santos JMS, Kyle GJ, Steadman KJ, Cichero JAY, Nissen LM.

JBI Database System Rev Implement Rep. 2018 Jan;16(1):71-86. doi: 10.11124/JBISRIR-2016-003334.


Diversity of pollination ecology in the Schismatoglottis Calyptrata Complex Clade (Araceae).

Hoe YC, Gibernau M, Wong SY.

Plant Biol (Stuttg). 2018 May;20(3):563-578. doi: 10.1111/plb.12687. Epub 2018 Feb 8.


Pre-Liver Transplant Muscle Loss Is a Risk Factor for Post-Liver Transplantation Left Ventricular Systolic Dysfunction.

Mathew A, Halegoua-De Marzio D, Reddy S, Wong SY, Cheung M, Mosca H, Guglielmo F, Halpern E, Sass DA, Doria C.

Ann Transplant. 2017 Dec 22;22:759-764.


Chronic liver disease is universal in children with biliary atresia living with native liver.

Lee WS, Ong SY, Foo HW, Wong SY, Kong CX, Seah RB, Ng RT.

World J Gastroenterol. 2017 Nov 21;23(43):7776-7784. doi: 10.3748/wjg.v23.i43.7776.


Dietary sugar intake was associated with increased body fatness but decreased cardiovascular mortality in Chinese elderly: an 11-year prospective study of Mr and Ms OS of Hong Kong.

Liu ZM, Tse LA, Chan D, Wong C, Wong SYS.

Int J Obes (Lond). 2018 Apr;42(4):808-816. doi: 10.1038/ijo.2017.292. Epub 2017 Nov 30.


The Effects of Family-Based Mindfulness Intervention on ADHD Symptomology in Young Children and Their Parents: A Randomized Control Trial.

Lo HHM, Wong SWL, Wong JYH, Yeung JWK, Snel E, Wong SYS.

J Atten Disord. 2017 Nov 1:1087054717743330. doi: 10.1177/1087054717743330. [Epub ahead of print]


Response to the Letter to the Editor by Simon D. Smith "Recall Tests Can Be Effective to Detect Mild Cognitive Impairment: A Response to Tsoi and Colleagues".

Chan JYC, Wong SYS, Tsoi KKF.

J Am Med Dir Assoc. 2017 Dec 1;18(12):1094-1095. doi: 10.1016/j.jamda.2017.10.001. No abstract available.


Incidence and mortality of kidney cancer: temporal patterns and global trends in 39 countries.

Wong MCS, Goggins WB, Yip BHK, Fung FDH, Leung C, Fang Y, Wong SYS, Ng CF.

Sci Rep. 2017 Nov 16;7(1):15698. doi: 10.1038/s41598-017-15922-4.

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