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Report from the 19th annual Western Canadian Gastrointestinal Cancer Consensus Conference; Winnipeg, Manitoba; 29-30 September 2017.

Kim CA, Ahmed S, Ahmed S, Brunet B, Chalchal H, Deobald R, Doll C, Dupre MP, Gordon V, Lee-Ying RM, Lim H, Liu D, Loree JM, McGhie JP, Mulder K, Park J, Yip B, Wong RP, Zaidi A; Western Canadian Gastrointestinal Cancer Group.

Curr Oncol. 2018 Aug;25(4):275-284. doi: 10.3747/co.25.4109. Epub 2018 Aug 14.


The helicase Pif1 functions in the template switching pathway of DNA damage bypass.

García-Rodríguez N, Wong RP, Ulrich HD.

Nucleic Acids Res. 2018 Sep 19;46(16):8347-8356. doi: 10.1093/nar/gky648.


Spatial separation between replisome- and template-induced replication stress signaling.

García-Rodríguez N, Morawska M, Wong RP, Daigaku Y, Ulrich HD.

EMBO J. 2018 May 2;37(9). pii: e98369. doi: 10.15252/embj.201798369. Epub 2018 Mar 26.


Monoubiquitylation of histone H2B contributes to the bypass of DNA damage during and after DNA replication.

Hung SH, Wong RP, Ulrich HD, Kao CF.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2205-E2214. doi: 10.1073/pnas.1612633114. Epub 2017 Feb 28.


Rapid Identification of Bacterial Antibiotic Resistance by qPCR in Infants with Gram-Negative Septicaemia: A Proof-of-Concept Study.

Lam HS, Chan KY, Ip M, Leung KT, Lo NW, Wong RP, Li K, Ng PC.

Neonatology. 2017;111(2):145-152. doi: 10.1159/000449279. Epub 2016 Oct 19.


Regulation of Circulating Hematopoietic Stem/Progenitor Cells in Preterm Infants with Septicemia.

Leung KT, Lam HS, Chan KY, Sit T, Wong RP, Yu JW, Li K, Ng PC.

Stem Cells Dev. 2016 Dec 1;25(23):1780-1787. Epub 2016 Oct 4.


Functions of Ubiquitin and SUMO in DNA Replication and Replication Stress.

García-Rodríguez N, Wong RP, Ulrich HD.

Front Genet. 2016 May 13;7:87. doi: 10.3389/fgene.2016.00087. eCollection 2016. Review.


National, Heart, Lung, and Blood Institute support of cardiac arrhythmia research.

Wong RP, Tinsley EA, Waclawiw MA, Krull HK, Lathrop DA.

Heart Rhythm. 2016 Jul;13(7):1570-2. doi: 10.1016/j.hrthm.2016.03.001. Epub 2016 Mar 2. No abstract available.


The Changing Paradigm of HIV-Related Heart Failure.

Shah MR, Wong RP.

Glob Heart. 2015 Dec;10(4):241-4. doi: 10.1016/j.gheart.2015.09.001. No abstract available.


Temporal changes in Plasmodium falciparum anti-malarial drug sensitivity in vitro and resistance-associated genetic mutations in isolates from Papua New Guinea.

Koleala T, Karl S, Laman M, Moore BR, Benjamin J, Barnadas C, Robinson LJ, Kattenberg JH, Javati S, Wong RP, Rosanas-Urgell A, Betuela I, Siba PM, Mueller I, Davis TM.

Malar J. 2015 Jan 28;14:37. doi: 10.1186/s12936-015-0560-3.


Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.

Venkatesan M, Gadalla NB, Stepniewska K, Dahal P, Nsanzabana C, Moriera C, Price RN, Mårtensson A, Rosenthal PJ, Dorsey G, Sutherland CJ, Guérin P, Davis TM, Ménard D, Adam I, Ademowo G, Arze C, Baliraine FN, Berens-Riha N, Björkman A, Borrmann S, Checchi F, Desai M, Dhorda M, Djimdé AA, El-Sayed BB, Eshetu T, Eyase F, Falade C, Faucher JF, Fröberg G, Grivoyannis A, Hamour S, Houzé S, Johnson J, Kamugisha E, Kariuki S, Kiechel JR, Kironde F, Kofoed PE, LeBras J, Malmberg M, Mwai L, Ngasala B, Nosten F, Nsobya SL, Nzila A, Oguike M, Otienoburu SD, Ogutu B, Ouédraogo JB, Piola P, Rombo L, Schramm B, Somé AF, Thwing J, Ursing J, Wong RP, Zeynudin A, Zongo I, Plowe CV, Sibley CH; ASAQ Molecular Marker Study Group; WWARN AL.

Am J Trop Med Hyg. 2014 Oct;91(4):833-43. doi: 10.4269/ajtmh.14-0031. Epub 2014 Jul 21. Erratum in: Am J Trop Med Hyg. 2015 May;92(5):1084.


Epiregulin gene expression as a biomarker of benefit from cetuximab in the treatment of advanced colorectal cancer.

Jonker DJ, Karapetis CS, Harbison C, O'Callaghan CJ, Tu D, Simes RJ, Malone DP, Langer C, Tebbutt N, Price TJ, Shapiro J, Siu LL, Wong RP, Bjarnason G, Moore MJ, Zalcberg JR, Khambata-Ford S.

Br J Cancer. 2014 Feb 4;110(3):648-55. doi: 10.1038/bjc.2013.753. Epub 2013 Dec 12.


Role of EIF5A2, a downstream target of Akt, in promoting melanoma cell invasion.

Khosravi S, Wong RP, Ardekani GS, Zhang G, Martinka M, Ong CJ, Li G.

Br J Cancer. 2014 Jan 21;110(2):399-408. doi: 10.1038/bjc.2013.688. Epub 2013 Oct 31.


Neutrophil CD64 for daily surveillance of systemic infection and necrotizing enterocolitis in preterm infants.

Lam HS, Cheung HM, Poon TC, Wong RP, Leung KT, Li K, Ng PC.

Clin Chem. 2013 Dec;59(12):1753-60. doi: 10.1373/clinchem.2013.209536. Epub 2013 Sep 17.


Association of bovine meat quality traits with genes included in the PPARG and PPARGC1A networks.

Sevane N, Armstrong E, Cortés O, Wiener P, Wong RP, Dunner S; GemQual Consortium.

Meat Sci. 2013 Jul;94(3):328-35. doi: 10.1016/j.meatsci.2013.02.014. Epub 2013 Mar 1.


Gut-associated biomarkers L-FABP, I-FABP, and TFF3 and LIT score for diagnosis of surgical necrotizing enterocolitis in preterm infants.

Ng EW, Poon TC, Lam HS, Cheung HM, Ma TP, Chan KY, Wong RP, Leung KT, Lam MM, Li K, Ng PC.

Ann Surg. 2013 Dec;258(6):1111-8. doi: 10.1097/SLA.0b013e318288ea96.


Cediranib with mFOLFOX6 vs bevacizumab with mFOLFOX6 in previously treated metastatic colorectal cancer.

Cunningham D, Wong RP, D'Haens G, Douillard JY, Robertson J, Stone AM, Van Cutsem E; HORIZON I study group.

Br J Cancer. 2013 Feb 19;108(3):493-502. doi: 10.1038/bjc.2012.545. Epub 2013 Jan 8.


Investigation of volatile organic biomarkers derived from Plasmodium falciparum in vitro.

Wong RP, Flematti GR, Davis TM.

Malar J. 2012 Sep 7;11:314. doi: 10.1186/1475-2875-11-314.


Bilateral multi-injection iliohypogastric-ilioinguinal nerve block in conjunction with neuraxial morphine is superior to neuraxial morphine alone for postcesarean analgesia.

Wolfson A, Lee AJ, Wong RP, Arheart KL, Penning DH.

J Clin Anesth. 2012 Jun;24(4):298-303. doi: 10.1016/j.jclinane.2011.09.007.


Elucidating nature's solutions to heart, lung, and blood diseases and sleep disorders.

Carey HV, Martin SL, Horwitz BA, Yan L, Bailey SM, Podrabsky J, Storz JF, Ortiz RM, Wong RP, Lathrop DA.

Circ Res. 2012 Mar 30;110(7):915-21. doi: 10.1161/CIRCRESAHA.111.255398.


In vitro antimalarial activity and drug interactions of fenofibric acid.

Wong RP, Davis TM.

Antimicrob Agents Chemother. 2012 Jun;56(6):2814-8. doi: 10.1128/AAC.05076-11. Epub 2012 Mar 19.


Elevated expression of Rad18 regulates melanoma cell proliferation.

Wong RP, Aguissa-Touré AH, Wani AA, Khosravi S, Martinka M, Martinka M, Li G.

Pigment Cell Melanoma Res. 2012 Mar;25(2):213-8. doi: 10.1111/j.1755-148X.2011.00948.x. Epub 2012 Jan 12.


Synthesis and antimalarial evaluation of novel isocryptolepine derivatives.

Whittell LR, Batty KT, Wong RP, Bolitho EM, Fox SA, Davis TM, Murray PE.

Bioorg Med Chem. 2011 Dec 15;19(24):7519-25. doi: 10.1016/j.bmc.2011.10.037. Epub 2011 Oct 20.


Development of a novel mouse model of severe glucose-6-phosphate dehydrogenase (G6PD)-deficiency for in vitro and in vivo assessment of hemolytic toxicity to red blood cells.

Ko CH, Li K, Li CL, Ng PC, Fung KP, James AE, Wong RP, Gu GJ, Fok TF.

Blood Cells Mol Dis. 2011 Oct 15;47(3):176-81. doi: 10.1016/j.bcmd.2011.07.003. Epub 2011 Aug 11.


Tumour suppressor ING1b maintains genomic stability upon replication stress.

Wong RP, Lin H, Khosravi S, Piche B, Jafarnejad SM, Chen DW, Li G.

Nucleic Acids Res. 2011 May;39(9):3632-42. doi: 10.1093/nar/gkq1337. Epub 2011 Jan 11.


Desbutyl-lumefantrine is a metabolite of lumefantrine with potent in vitro antimalarial activity that may influence artemether-lumefantrine treatment outcome.

Wong RP, Salman S, Ilett KF, Siba PM, Mueller I, Davis TM.

Antimicrob Agents Chemother. 2011 Mar;55(3):1194-8. doi: 10.1128/AAC.01312-10. Epub 2011 Jan 3.


Molecular assessment of Plasmodium falciparum resistance to antimalarial drugs in Papua New Guinea using an extended ligase detection reaction fluorescent microsphere assay.

Wong RP, Karunajeewa H, Mueller I, Siba P, Zimmerman PA, Davis TM.

Antimicrob Agents Chemother. 2011 Feb;55(2):798-805. doi: 10.1128/AAC.00939-10. Epub 2010 Nov 15.


Versatile solution for growing thin films of conducting polymers.

D'Arcy JM, Tran HD, Tung VC, Tucker-Schwartz AK, Wong RP, Yang Y, Kaner RB.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19673-8. doi: 10.1073/pnas.1008595107. Epub 2010 Nov 1.


The ING family tumor suppressors: from structure to function.

Aguissa-Touré AH, Wong RP, Li G.

Cell Mol Life Sci. 2011 Jan;68(1):45-54. doi: 10.1007/s00018-010-0509-1. Epub 2010 Aug 29. Review.


Early diagnosis of intra-abdominal inflammation and sepsis by neutrophil CD64 expression in newborns.

Lam HS, Wong SP, Cheung HM, Chu WC, Wong RP, Chui KM, Liu FY, Li K, Fok TF, Ng PC.

Neonatology. 2011;99(2):118-24. doi: 10.1159/000311289. Epub 2010 Aug 24.


Pain and emotional well-being outcomes in Southwest Oncology Group-directed intergroup trial S0205: a phase III study comparing gemcitabine plus cetuximab versus gemcitabine as first-line therapy in patients with advanced pancreas cancer.

Moinpour CM, Vaught NL, Goldman B, Redman MW, Philip PA, Millwood B, Lippman SM, Seay TE, Flynn PJ, O'Reilly EM, Rowland KM, Wong RP, Benedetti J, Blanke CD.

J Clin Oncol. 2010 Aug 1;28(22):3611-6. doi: 10.1200/JCO.2009.25.8285. Epub 2010 Jul 6.


Transient upregulation of PGC-1alpha diminishes cardiac ischemia tolerance via upregulation of ANT1.

Lynn EG, Stevens MV, Wong RP, Carabenciov D, Jacobson J, Murphy E, Sack MN.

J Mol Cell Cardiol. 2010 Oct;49(4):693-8. doi: 10.1016/j.yjmcc.2010.06.008. Epub 2010 Jul 1.


Host-response biomarkers for diagnosis of late-onset septicemia and necrotizing enterocolitis in preterm infants.

Ng PC, Ang IL, Chiu RW, Li K, Lam HS, Wong RP, Chui KM, Cheung HM, Ng EW, Fok TF, Sung JJ, Lo YM, Poon TC.

J Clin Invest. 2010 Aug;120(8):2989-3000. doi: 10.1172/JCI40196. Epub 2010 Jul 1.


BRG1 expression is increased in human cutaneous melanoma.

Lin H, Wong RP, Martinka M, Li G.

Br J Dermatol. 2010 Sep;163(3):502-10. doi: 10.1111/j.1365-2133.2010.09851.x. Epub 2010 Aug 12.


In vitro sensitivity of Plasmodium falciparum to conventional and novel antimalarial drugs in Papua New Guinea.

Wong RP, Lautu D, Tavul L, Hackett SL, Siba P, Karunajeewa HA, Ilett KF, Mueller I, Davis TM.

Trop Med Int Health. 2010 Mar;15(3):342-9. doi: 10.1111/j.1365-3156.2009.02463.x. Epub 2010 Jan 11.


A comparative study of a flow-cytometry-based assessment of in vitro Plasmodium falciparum drug sensitivity.

Karl S, Wong RP, St Pierre TG, Davis TM.

Malar J. 2009 Dec 14;8:294. doi: 10.1186/1475-2875-8-294.


Loss of SNF5 expression correlates with poor patient survival in melanoma.

Lin H, Wong RP, Martinka M, Li G.

Clin Cancer Res. 2009 Oct 15;15(20):6404-11. doi: 10.1158/1078-0432.CCR-09-1135. Epub 2009 Oct 6.


The role of ING tumor suppressors in UV stress response and melanoma progression.

Li J, Wang Y, Wong RP, Li G.

Curr Drug Targets. 2009 May;10(5):455-64. Review.


Oxidative challenge and glucose-6-phosphate dehydrogenase activity of preterm and term neonatal red blood cells.

Ko CH, Wong RP, Ng PC, Li K, Chui KM, Yuen PM, Fok TF.

Neonatology. 2009;96(2):96-101. doi: 10.1159/000205720. Epub 2009 Mar 4.


Statins as potential antimalarial drugs: low relative potency and lack of synergy with conventional antimalarial drugs.

Wong RP, Davis TM.

Antimicrob Agents Chemother. 2009 May;53(5):2212-4. doi: 10.1128/AAC.01469-08. Epub 2009 Mar 2.


Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.

Peña PV, Hom RA, Hung T, Lin H, Kuo AJ, Wong RP, Subach OM, Champagne KS, Zhao R, Verkhusha VV, Li G, Gozani O, Kutateladze TG.

J Mol Biol. 2008 Jul 4;380(2):303-12. doi: 10.1016/j.jmb.2008.04.061. Epub 2008 May 2.


Pro-oxidative effects of Chinese herbal medicine on G6PD-deficient erythrocytes in vitro.

Ko CH, Li K, Ng PC, Fung KP, Wong RP, Chui KM, Gu GJ, Yung E, Fok TF.

Toxicol In Vitro. 2008 Aug;22(5):1222-7. doi: 10.1016/j.tiv.2008.03.017. Epub 2008 Apr 15.


NAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of the tumour suppressor p33(ING1b).

Garate M, Wong RP, Campos EI, Wang Y, Li G.

EMBO Rep. 2008 Jun;9(6):576-81. doi: 10.1038/embor.2008.48. Epub 2008 Apr 4.


Myeloid leukemia-1 expression in benign and malignant melanocytic lesions.

Wong RP, Khosravi S, Martinka M, Li G.

Oncol Rep. 2008 Apr;19(4):933-7.


Development of pan-specific antibody against trimethyllysine for protein research.

Liang Z, Wong RP, Li LH, Jiang H, Xiao H, Li G.

Proteome Sci. 2008 Jan 22;6:2. doi: 10.1186/1477-5956-6-2.


Use of spinal anesthesia does not reduce intraoperative blood loss.

Wong RP, Carter HB, Wolfson A, Faustin C, Cohen SR, Wu CL.

Urology. 2007 Sep;70(3):523-6.


The role of integrin-linked kinase in melanoma cell migration, invasion, and tumor growth.

Wong RP, Ng P, Dedhar S, Li G.

Mol Cancer Ther. 2007 Jun;6(6):1692-700.


Self-rated health in the unwell elderly presenting to the emergency department.

Wong DD, Wong RP, Caplan GA.

Emerg Med Australas. 2007 Jun;19(3):196-202.


The ING1b tumor suppressor facilitates nucleotide excision repair by promoting chromatin accessibility to XPA.

Kuo WH, Wang Y, Wong RP, Campos EI, Li G.

Exp Cell Res. 2007 May 1;313(8):1628-38. Epub 2007 Feb 22.


p53-R273H gains new function in induction of drug resistance through down-regulation of procaspase-3.

Wong RP, Tsang WP, Chau PY, Co NN, Tsang TY, Kwok TT.

Mol Cancer Ther. 2007 Mar;6(3):1054-61.

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