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Single-center experience with radium-223 in patients with castration-resistant prostate cancer and bone metastases.

Kapoor A, Wong NC, Wang Y, Mukherjee S, Hotte S, Dayes I, Lukka H.

Asian J Androl. 2019 Sep 13. doi: 10.4103/aja.aja_66_19. [Epub ahead of print] No abstract available.


Apabetalone (RVX-208) reduces vascular inflammation in vitro and in CVD patients by a BET-dependent epigenetic mechanism.

Tsujikawa LM, Fu L, Das S, Halliday C, Rakai BD, Stotz SC, Sarsons CD, Gilham D, Daze E, Wasiak S, Studer D, Rinker KD, Sweeney M, Johansson JO, Wong NCW, Kulikowski E.

Clin Epigenetics. 2019 Jul 12;11(1):102. doi: 10.1186/s13148-019-0696-z.


Patient centered care for prostate cancer-how can artificial intelligence and machine learning help make the right decision for the right patient?

Wong NC, Shayegan B.

Ann Transl Med. 2019 Mar;7(Suppl 1):S1. doi: 10.21037/atm.2019.01.13. No abstract available.


Phase III Trial of Intravenous Mannitol Versus Placebo During Nephron-sparing Surgery: Post Hoc Analysis of 3-yr Outcomes.

Wong NC, Alvim RG, Sjoberg DD, Shingarev R, Power NE, Spaliviero M, Murray KS, Benfante NE, Hakimi AA, Russo P, Coleman JA.

Eur Urol Focus. 2019 Nov;5(6):977-979. doi: 10.1016/j.euf.2019.04.003. Epub 2019 Apr 25.


The potential risk of tumor progression after use of dehydrated human amnion/chorion membrane allograft in a positive margin resection model.

Alvim RG, Hughes C, Somma A, Nagar KK, Wong NC, La Rosa S, Monette S, Kim K, Coleman JA.

Ther Adv Urol. 2019 Mar 29;11:1756287219837771. doi: 10.1177/1756287219837771. eCollection 2019 Jan-Dec.


Upfront cytoreductive nephrectomy vs. upfront systemic therapy in metastatic kidney cancer.

Kapoor A, Wong ECL, Fang W, Wong NC.

Can Urol Assoc J. 2019 Feb 26:E377-E381. doi: 10.5489/cuaj.5666. [Epub ahead of print] No abstract available.


Early Phase I Study of a 99mTc-Labeled Anti-Programmed Death Ligand-1 (PD-L1) Single-Domain Antibody in SPECT/CT Assessment of PD-L1 Expression in Non-Small Cell Lung Cancer.

Xing Y, Chand G, Liu C, Cook GJR, O'Doherty J, Zhao L, Wong NCL, Meszaros LK, Ting HH, Zhao J.

J Nucl Med. 2019 Sep;60(9):1213-1220. doi: 10.2967/jnumed.118.224170. Epub 2019 Feb 22.


Off- vs. On-Pump Coronary Artery Bypass Grafting Long-Term Survival is Driven by Incompleteness of Revascularisation.

Thakur U, Nerlekar N, Muthalaly RG, Comella A, Wong NC, Cameron JD, Harper RW, Smith JA, Brown AJ.

Heart Lung Circ. 2020 Jan;29(1):149-155. doi: 10.1016/j.hlc.2018.11.019. Epub 2018 Dec 13.


Perceived deception in negotiation: Consequences and the mediating role of trust.

Au AKC, Wong NCQ.

J Soc Psychol. 2019;159(4):459-473. doi: 10.1080/00224545.2019.1567454. Epub 2019 Jan 25.


Early-Life Formation of the Microbial and Immunological Environment of the Human Airways.

Pattaroni C, Watzenboeck ML, Schneidegger S, Kieser S, Wong NC, Bernasconi E, Pernot J, Mercier L, Knapp S, Nicod LP, Marsland CP, Roth-Kleiner M, Marsland BJ.

Cell Host Microbe. 2018 Dec 12;24(6):857-865.e4. doi: 10.1016/j.chom.2018.10.019. Epub 2018 Nov 29.


Open ureteroureterostomy for repair of upper-pole ectopic ureters in children with duplex systems: is stenting really necessary?

Wong NC, Braga LH.

J Pediatr Urol. 2019 Feb;15(1):72.e1-72.e7. doi: 10.1016/j.jpurol.2018.10.014. Epub 2018 Oct 24.


Apabetalone downregulates factors and pathways associated with vascular calcification.

Gilham D, Tsujikawa LM, Sarsons CD, Halliday C, Wasiak S, Stotz SC, Jahagirdar R, Sweeney M, Johansson JO, Wong NCW, Kalantar-Zadeh K, Kulikowski E.

Atherosclerosis. 2019 Jan;280:75-84. doi: 10.1016/j.atherosclerosis.2018.11.002. Epub 2018 Nov 14.


A novel role for Lyl1 in primitive erythropoiesis.

Chiu SK, Saw J, Huang Y, Sonderegger SE, Wong NC, Powell DR, Beck D, Pimanda JE, Tremblay CS, Curtis DJ.

Development. 2018 Oct 11;145(19). pii: dev162990. doi: 10.1242/dev.162990.


Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells.

Tremblay CS, Saw J, Chiu SK, Wong NC, Tsyganov K, Ghotb S, Graham AN, Yan F, Guirguis AA, Sonderegger SE, Lee N, Kalitsis P, Reynolds J, Ting SB, Powell DR, Jane SM, Curtis DJ.

Nat Commun. 2018 Aug 30;9(1):3535. doi: 10.1038/s41467-018-06021-7.


The Effect of Bromodomain and Extra-Terminal Inhibitor Apabetalone on Attenuated Coronary Atherosclerotic Plaque: Insights from the ASSURE Trial.

Shishikura D, Kataoka Y, Honda S, Takata K, Kim SW, Andrews J, Psaltis PJ, Sweeney M, Kulikowski E, Johansson J, Wong NCW, Nicholls SJ.

Am J Cardiovasc Drugs. 2019 Feb;19(1):49-57. doi: 10.1007/s40256-018-0298-8.


Regulation of apolipoprotein A-I gene expression by the histamine H1 receptor: Requirement for NF-κB.

Haas MJ, Jurado-Flores M, Hammoud R, Plazarte G, Onstead-Haas L, Wong NCW, Mooradian AD.

Life Sci. 2018 Sep 1;208:102-110. doi: 10.1016/j.lfs.2018.07.022. Epub 2018 Jul 18.


Use of machine learning to predict early biochemical recurrence after robot-assisted prostatectomy.

Wong NC, Lam C, Patterson L, Shayegan B.

BJU Int. 2019 Jan;123(1):51-57. doi: 10.1111/bju.14477. Epub 2018 Aug 5.


Mouse Monoclonal Antibodies Against Progranulin (PGRN/GEP) as Therapeutics in Preclinical Cancer Models.

Yip CW, Cheung PFY, Wong NCL, Fung SW, Cheung ST.

Methods Mol Biol. 2018;1806:131-144. doi: 10.1007/978-1-4939-8559-3_10.


Benefit of Apabetalone on Plasma Proteins in Renal Disease.

Wasiak S, Tsujikawa LM, Halliday C, Stotz SC, Gilham D, Jahagirdar R, Kalantar-Zadeh K, Robson R, Sweeney M, Johansson JO, Wong NC, Kulikowski E.

Kidney Int Rep. 2017 Dec 8;3(3):711-721. doi: 10.1016/j.ekir.2017.12.001. eCollection 2018 May.


Profiling DNA methylation differences between inbred mouse strains on the Illumina Human Infinium MethylationEPIC microarray.

Gujar H, Liang JW, Wong NC, Mozhui K.

PLoS One. 2018 Mar 12;13(3):e0193496. doi: 10.1371/journal.pone.0193496. eCollection 2018.


The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection.

Muscat AM, Wong NC, Drummond KJ, Algar EM, Khasraw M, Verhaak R, Field K, Rosenthal MA, Ashley DM.

Oncotarget. 2017 Dec 15;9(8):7844-7858. doi: 10.18632/oncotarget.23541. eCollection 2018 Jan 30.


CUA/EUREP Exchange Program: Prague 2017.

Wong NC.

Can Urol Assoc J. 2017 Oct;11(10):357. doi: 10.5489/cuaj.4921. No abstract available.


Inhibition of hepatic apolipoprotein A-I gene expression by histamine.

Haas MJ, Plazarte M, Chamseddin A, Onstead-Haas L, Wong NCW, Plazarte G, Mooradian AD.

Eur J Pharmacol. 2018 Mar 15;823:49-57. doi: 10.1016/j.ejphar.2018.01.035. Epub 2018 Feb 4.


High-intensity Focused Ultrasound (HIFU) as salvage therapy for radio-recurrent prostate cancer: predictors of disease response.

Dason S, Wong NC, Allard CB, Hoogenes J, Orovan W, Shayegan B.

Int Braz J Urol. 2018 Mar-Apr;44(2):248-257. doi: 10.1590/S1677-5538.IBJU.2017.0025.


Images in urology: Localized primary amyloidosis of the urinary bladder.

Varghese S, Wong NC, Shayegan B.

Can Urol Assoc J. 2018 Jan;12(1):E42-E44. doi: 10.5489/cuaj.4825. Epub 2017 Dec 1. No abstract available.


Positive surgical margin rates during the robot-assisted laparoscopic radical prostatectomy learning curve of an experienced laparoscopic surgeon.

Adili AF, Di Giovanni J, Kolesar E, Wong NC, Hoogenes J, Dason S, Shayegan B.

Can Urol Assoc J. 2017 Nov;11(11):E409-E413. doi: 10.5489/cuaj.4588.


RVX-297, a BET Bromodomain Inhibitor, Has Therapeutic Effects in Preclinical Models of Acute Inflammation and Autoimmune Disease.

Jahagirdar R, Attwell S, Marusic S, Bendele A, Shenoy N, McLure KG, Gilham D, Norek K, Hansen HC, Yu R, Tobin J, Wagner GS, Young PR, Wong NCW, Kulikowski E.

Mol Pharmacol. 2017 Dec;92(6):694-706. doi: 10.1124/mol.117.110379. Epub 2017 Sep 29.


CUA-AUA International Fellows Program: Boston 2017.

Wong NC.

Can Urol Assoc J. 2017 Aug;11(8):230. doi: 10.5489/cuaj.4818. No abstract available.


Techniques: Utility of a 3D printed bladder model for teaching minimally invasive urethrovesical anastomosis.

Wong NC, Hoogenes J, Guo Y, Quantz MA, Matsumoto ED.

Can Urol Assoc J. 2017 Jul;11(7):E321-E322. doi: 10.5489/cuaj.4262. Epub 2017 Jul 11. No abstract available.


Case: Spontaneous regression of post-radical prostatectomy prostate-specific antigen elevation without adjuvant therapy in a patient with lymph node metastasis.

Lee T, Guo Y, Vij S, Bansal R, Wong NC, Shayegan B.

Can Urol Assoc J. 2017 Jul;11(7):E315-E317. doi: 10.5489/cuaj.4324. Epub 2017 Jul 11.


Downregulation of the Complement Cascade In Vitro, in Mice and in Patients with Cardiovascular Disease by the BET Protein Inhibitor Apabetalone (RVX-208).

Wasiak S, Gilham D, Tsujikawa LM, Halliday C, Calosing C, Jahagirdar R, Johansson J, Sweeney M, Wong NC, Kulikowski E.

J Cardiovasc Transl Res. 2017 Aug;10(4):337-347. doi: 10.1007/s12265-017-9755-z. Epub 2017 May 31.


Can it wait? A systematic review of immediate vs. delayed surgical repair of penile fractures.

Wong NC, Dason S, Bansal RK, Davies TO, Braga LH.

Can Urol Assoc J. 2017 Jan-Feb;11(1-2):53-60. doi: 10.5489/cuaj.4032.


Management of pelvic fracture-associated urethral injuries: A survey of Canadian urologists.

Wong NC, Allard CB, Dason S, Farrugia P, Bhandari M, Davies TO.

Can Urol Assoc J. 2017 Mar-Apr;11(3-4):E74-E78. doi: 10.5489/cuaj.4154. Epub 2017 Mar 16.


Continuous antibiotic prophylaxis in the setting of prenatal hydronephrosis and vesicoureteral reflux.

Wong NC, Koyle MA, Braga LH.

Can Urol Assoc J. 2017 Jan-Feb;11(1-2Suppl1):S20-S24. doi: 10.5489/cuaj.4387. Review.


Data on gene and protein expression changes induced by apabetalone (RVX-208) in ex vivo treated human whole blood and primary hepatocytes.

Wasiak S, Gilham D, Tsujikawa LM, Halliday C, Norek K, Patel RG, McLure KG, Young PR, Gordon A, Kulikowski E, Johansson J, Sweeney M, Wong NC.

Data Brief. 2016 Jul 29;8:1280-8. doi: 10.1016/j.dib.2016.07.047. eCollection 2016 Sep.


Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas.

Lim AM, Wong NC, Pidsley R, Zotenko E, Corry J, Dobrovic A, Clark SJ, Rischin D, Solomon B.

Clin Epigenetics. 2016 Jul 18;8:74. doi: 10.1186/s13148-016-0235-0. eCollection 2016.


Smoking Is So Ew!: College Smokers' Reactions to Health- Versus Social-Focused Antismoking Threat Messages.

Wong NC, Nisbett GS, Harvell LA.

Health Commun. 2017 Apr;32(4):451-460. doi: 10.1080/10410236.2016.1140264. Epub 2016 Jun 17.


Pro-inflammatory signaling by 24,25-dihydroxyvitamin D3 in HepG2 cells.

Wehmeier K, Onstead-Haas LM, Wong NC, Mooradian AD, Haas MJ.

J Mol Endocrinol. 2016 Aug;57(2):87-96. doi: 10.1530/JME-16-0009. Epub 2016 May 27.


Corrigendum to "RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease" [Atherosclerosis 247 (2016) 48-57].

Gilham D, Wasiak S, Tsujikawa LM, Halliday C, Norek K, Patel RG, Kulikowski E, Johansson J, Sweeney M, Wong NC.

Atherosclerosis. 2016 Oct;253:345. doi: 10.1016/j.atherosclerosis.2016.05.012. Epub 2016 May 20. No abstract available.


Effects of the BET-inhibitor, RVX-208 on the HDL lipidome and glucose metabolism in individuals with prediabetes: A randomized controlled trial.

Siebel AL, Trinh SK, Formosa MF, Mundra PA, Natoli AK, Reddy-Luthmoodoo M, Huynh K, Khan AA, Carey AL, van Hall G, Cobelli C, Dalla-Man C, Otvos JD, Rye KA, Johansson J, Gordon A, Wong NC, Sviridov D, Barter P, Duffy SJ, Meikle PJ, Kingwell BA.

Metabolism. 2016 Jun;65(6):904-14. doi: 10.1016/j.metabol.2016.03.002. Epub 2016 Mar 8.


MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing.

Wong NC, Pope BJ, Candiloro IL, Korbie D, Trau M, Wong SQ, Mikeska T, Zhang X, Pitman M, Eggers S, Doyle SR, Dobrovic A.

BMC Bioinformatics. 2016 Feb 24;17:98. doi: 10.1186/s12859-016-0950-8.


RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease.

Gilham D, Wasiak S, Tsujikawa LM, Halliday C, Norek K, Patel RG, Kulikowski E, Johansson J, Sweeney M, Wong NC, Gordon A, McLure K, Young P.

Atherosclerosis. 2016 Apr;247:48-57. doi: 10.1016/j.atherosclerosis.2016.01.036. Epub 2016 Jan 22. Erratum in: Atherosclerosis. 2016 Oct;253:345.


Misuse of ultrasound for palpable undescended testis by primary care providers: A prospective study.

Wong NC, Bansal RK, Lorenzo AJ, DeMaria J, Braga LH.

Can Urol Assoc J. 2015 Nov-Dec;9(11-12):387-90. doi: 10.5489/cuaj.3242. Epub 2015 Dec 14.


Enkephalin Disinhibits Mu Opioid Receptor-Rich Striatal Patches via Delta Opioid Receptors.

Banghart MR, Neufeld SQ, Wong NC, Sabatini BL.

Neuron. 2015 Dec 16;88(6):1227-1239. doi: 10.1016/j.neuron.2015.11.010. Epub 2015 Dec 6.


The 10 000-hour rule.

Wong NC.

Can Urol Assoc J. 2015 Sep-Oct;9(9-10):299. doi: 10.5489/cuaj.3267. No abstract available.


Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat.

Wong NC, Pope BJ, Candiloro I, Korbie D, Trau M, Wong SQ, Mikeska T, van Denderen BJ, Thompson EW, Eggers S, Doyle SR, Dobrovic A.

Gigascience. 2015 Nov 26;4:55. doi: 10.1186/s13742-015-0098-x. eCollection 2015.


An evaluation of RVX-208 for the treatment of atherosclerosis.

Nikolic D, Rizzo M, Mikhailidis DP, Wong NC, Banach M.

Expert Opin Investig Drugs. 2015;24(10):1389-98. doi: 10.1517/13543784.2015.1083010. Review.


Capillary hemangioma of the testis: A rare benign tumour.

Wong NC, Dason S, Pozdnyakov S, Alexopoulou I, Greenspan M.

Can Urol Assoc J. 2015 Mar-Apr;9(3-4):133-5. doi: 10.5489/cuaj.2318.


The influence of pre-operative hormonal stimulation on hypospadias repair.

Wong NC, Braga LH.

Front Pediatr. 2015 Apr 22;3:31. doi: 10.3389/fped.2015.00031. eCollection 2015. Review.


Paediatric leukaemia DNA methylation profiling using MBD enrichment and SOLiD sequencing on archival bone marrow smears.

Wong NC, Meredith GD, Marnellos G, Dudas M, Parkinson-Bates M, Halemba MS, Chatterton Z, Maksimovic J, Ashley DM, Mechinaud F, Craig JM, Saffery R.

Gigascience. 2015 Mar 18;4:11. doi: 10.1186/s13742-015-0050-0. eCollection 2015.

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