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Antimalarial activity of primaquine operates via a two-step biochemical relay.

Camarda G, Jirawatcharadech P, Priestley RS, Saif A, March S, Wong MHL, Leung S, Miller AB, Baker DA, Alano P, Paine MJI, Bhatia SN, O'Neill PM, Ward SA, Biagini GA.

Nat Commun. 2019 Jul 19;10(1):3226. doi: 10.1038/s41467-019-11239-0.


Circulating Hybrid Cells Join the Fray of Circulating Cellular Biomarkers.

Sutton TL, Walker BS, Wong MH.

Cell Mol Gastroenterol Hepatol. 2019 Jul 15. pii: S2352-345X(19)30089-X. doi: 10.1016/j.jcmgh.2019.07.002. [Epub ahead of print] Review.


A Comprehensive Analysis of Traumatic Rib Fractures in an Acute General Hospital in Singapore.

Maduka AKI, Lin GJ, Lim WW, Lee DJK, Kang ML, Venkatesan K, Wong MH, Tiong Thye JG.

J Emerg Trauma Shock. 2019 Apr-Jun;12(2):145-149. doi: 10.4103/JETS.JETS_72_18.


Effects of Mental Health Paraprofessional Training for Filipina Foreign Domestic Workers in Singapore.

Wong MHM, Keng SL, Buck PJ, Suthendran S, Wessels A, Østbye T.

J Immigr Minor Health. 2019 Jun 10. doi: 10.1007/s10903-019-00907-4. [Epub ahead of print]


Sorption Mechanism, Kinetics, and Isotherms of Di- n-butyl Phthalate to Different Soil Particle-Size Fractions.

Xiang L, Wang XD, Chen XH, Mo CH, Li YW, Li H, Cai QY, Zhou DM, Wong MH, Li QX.

J Agric Food Chem. 2019 May 1;67(17):4734-4745. doi: 10.1021/acs.jafc.8b06357. Epub 2019 Apr 22.


Erratum to: Efficient generation of complete sequences of MDR-encoding plasmids by rapid assembly of MinION barcoding sequencing data.

Li R, Xie M, Dong N, Lin D, Yang X, Wong MHY, Chan EW, Chen S.

Gigascience. 2019 Mar 1;8(3). pii: giz031. doi: 10.1093/gigascience/giz031. No abstract available.


Mercury methylation by Geobacter metallireducens GS-15 in the presence of Skeletonema costatum.

Ding LY, Zhang YY, Zhang LJ, Fang F, He NN, Liang P, Wu SC, Wong MH, Tao HC.

Sci Total Environ. 2019 Jun 25;671:208-214. doi: 10.1016/j.scitotenv.2019.03.222. Epub 2019 Mar 15.


MolTarPred: A web tool for comprehensive target prediction with reliability estimation.

Peón A, Li H, Ghislat G, Leung KS, Wong MH, Lu G, Ballester PJ.

Chem Biol Drug Des. 2019 Mar 27. doi: 10.1111/cbdd.13516. [Epub ahead of print]


Classical scoring functions for docking are unable to exploit large volumes of structural and interaction data.

Li H, Peng J, Sidorov P, Leung Y, Leung KS, Wong MH, Lu G, Ballester PJ.

Bioinformatics. 2019 Mar 14. pii: btz183. doi: 10.1093/bioinformatics/btz183. [Epub ahead of print]


Chloroplast-selective gene delivery and expression in planta using chitosan-complexed single-walled carbon nanotube carriers.

Kwak SY, Lew TTS, Sweeney CJ, Koman VB, Wong MH, Bohmert-Tatarev K, Snell KD, Seo JS, Chua NH, Strano MS.

Nat Nanotechnol. 2019 May;14(5):447-455. doi: 10.1038/s41565-019-0375-4. Epub 2019 Feb 25.


Effects of biochar on bacterial communities in a newly established landfill cover topsoil.

Wong JTF, Chen X, Deng W, Chai Y, Ng CWW, Wong MH.

J Environ Manage. 2019 Apr 15;236:667-673. doi: 10.1016/j.jenvman.2019.02.010. Epub 2019 Feb 14.


Co-metabolic degradation of the antibiotic ciprofloxacin by the enriched bacterial consortium XG and its bacterial community composition.

Feng NX, Yu J, Xiang L, Yu LY, Zhao HM, Mo CH, Li YW, Cai QY, Wong MH, Li QX.

Sci Total Environ. 2019 May 15;665:41-51. doi: 10.1016/j.scitotenv.2019.01.322. Epub 2019 Feb 4.


The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM.

Wong MH, Samal AB, Lee M, Vlach J, Novikov N, Niedziela-Majka A, Feng JY, Koltun DO, Brendza KM, Kwon HJ, Schultz BE, Sakowicz R, Saad JS, Papalia GA.

J Mol Biol. 2019 Mar 29;431(7):1440-1459. doi: 10.1016/j.jmb.2019.02.001. Epub 2019 Feb 10.


Effects of biochar on the ecological performance of a subtropical landfill.

Chen XW, Wong JTF, Chen ZT, Tang TWL, Guo HW, Leung AOW, Ng CWW, Wong MH.

Sci Total Environ. 2018 Dec 10;644:963-975. doi: 10.1016/j.scitotenv.2018.06.379. Epub 2018 Jul 11.


Fermented food waste for culturing jade perch and Nile tilapia: Growth performance and health risk assessment based on metal/loids.

Mo WY, Man YB, Zhang F, Wong MH.

J Environ Manage. 2019 Apr 15;236:236-244. doi: 10.1016/j.jenvman.2019.01.102. Epub 2019 Feb 5.


A role for BATF3 in TH9 differentiation and T-cell-driven mucosal pathologies.

Tsuda M, Hamade H, Thomas LS, Salumbides BC, Potdar AA, Wong MH, Nunnelee JS, Stamps JT, Neutzsky-Wulff AV, Barrett RJ, Wang Y, Tang J, Funari VA, Targan SR, Michelsen KS.

Mucosal Immunol. 2019 May;12(3):644-655. doi: 10.1038/s41385-018-0122-4. Epub 2019 Jan 7.


Formation of dioxins from triclosan with active chlorine: A potential risk assessment.

Wu JL, Ji F, Zhang H, Hu C, Wong MH, Hu D, Cai Z.

J Hazard Mater. 2019 Apr 5;367:128-136. doi: 10.1016/j.jhazmat.2018.12.088. Epub 2018 Dec 23.


Human health risk assessment of antibiotic resistance associated with antibiotic residues in the environment: A review.

Ben Y, Fu C, Hu M, Liu L, Wong MH, Zheng C.

Environ Res. 2019 Feb;169:483-493. doi: 10.1016/j.envres.2018.11.040. Epub 2018 Nov 26. Review.


A New, Long-Lived, Jupiter Mesoscale Wave Observed at Visible Wavelengths.

Simon AA, Hueso R, Iñurrigarro P, Sánchez-Lavega A, MoralesJuberías R, Cosentino R, Fletcher LN, Wong MH, Hsu AI, de Pater I, Orton GS, Colas F, Delcroix M, Peach D, Gómez-Forrellad JM.

Astron J. 2018 Aug;156(2). pii: 79. doi: 10.3847/1538-3881/aacaf5. Epub 2018 Aug 2.


Jupiter's Mesoscale Waves Observed at 5 μm by Ground-based Observations and Juno JIRAM.

Fletcher LN, Melin H, Adriani A, Simon AA, Sanchez-Lavega A, Donnelly PT, Antuñano A, Orton GS, Hueso R, Kraaikamp E, Wong MH, Barnett M, Moriconi ML, Altieri F, Sindoni G.

Astron J. 2018 Aug;156(2). pii: 67. doi: 10.3847/1538-3881/aace02. Epub 2018 Jul 26.


The role of sewage sludge biochar in methylmercury formation and accumulation in rice.

Zhang J, Wu S, Xu Z, Wang M, Man YB, Christie P, Liang P, Shan S, Wong MH.

Chemosphere. 2019 Mar;218:527-533. doi: 10.1016/j.chemosphere.2018.11.090. Epub 2018 Nov 17.


Cultivar-Dependent Accumulation and Translocation of Perfluorooctanesulfonate among Lettuce ( Lactuca sativa L.) Cultivars Grown on Perfluorooctanesulfonate-Contaminated Soil.

Yu PF, Xiang L, Li XH, Ding ZR, Mo CH, Li YW, Li H, Cai QY, Zhou DM, Wong MH.

J Agric Food Chem. 2018 Dec 19;66(50):13096-13106. doi: 10.1021/acs.jafc.8b04548. Epub 2018 Dec 4.


Polymethacrylamide and Carbon Composites that Grow, Strengthen, and Self-Repair using Ambient Carbon Dioxide Fixation.

Kwak SY, Giraldo JP, Lew TTS, Wong MH, Liu P, Yang YJ, Koman VB, McGee MK, Olsen BD, Strano MS.

Adv Mater. 2018 Nov;30(46):e1804037. doi: 10.1002/adma.201804037. Epub 2018 Oct 9.


Inhibitory effects of Skeletonema costatum on mercury methylation by Geobacter sulfurreducens PCA.

Ding LY, He NN, Yang S, Zhang LJ, Liang P, Wu SC, Wong MH, Tao HC.

Chemosphere. 2019 Feb;216:179-185. doi: 10.1016/j.chemosphere.2018.10.121. Epub 2018 Oct 18.


Autoperforation of 2D materials for generating two-terminal memristive Janus particles.

Liu P, Liu AT, Kozawa D, Dong J, Yang JF, Koman VB, Saccone M, Wang S, Son Y, Wong MH, Strano MS.

Nat Mater. 2018 Nov;17(11):1005-1012. doi: 10.1038/s41563-018-0197-z. Epub 2018 Oct 23.


Role of phosphoric acid in the bioavailability of potentially toxic elements in hydrochars produced by hydrothermal carbonisation of sewage sludge.

Zhang Y, Deng Q, Wang M, Zhang J, Man YB, Shan S, Wu S, Liang P, Cao Y, Song C, Luo L, Lin L, Christie P, Wong MH.

Waste Manag. 2018 Sep;79:232-239. doi: 10.1016/j.wasman.2018.07.045. Epub 2018 Aug 1.


Failure of the Anti-Inflammatory Parasitic Worm Product ES-62 to Provide Protection in Mouse Models of Type I Diabetes, Multiple Sclerosis, and Inflammatory Bowel Disease.

Doonan J, Thomas D, Wong MH, Ramage HJ, Al-Riyami L, Lumb FE, Bell KS, Fairlie-Clarke KJ, Suckling CJ, Michelsen KS, Jiang HR, Cooke A, Harnett MM, Harnett W.

Molecules. 2018 Oct 17;23(10). pii: E2669. doi: 10.3390/molecules23102669.


Discovering Genetic Factors for psoriasis through exhaustively searching for significant second order SNP-SNP interactions.

Lee KY, Leung KS, Tang NLS, Wong MH.

Sci Rep. 2018 Oct 12;8(1):15186. doi: 10.1038/s41598-018-33493-w.


Development and Validation of the Singapore Thyroid Eye Disease Quality of Life Questionnaire.

Wong MHY, Fenwick E, Aw AT, Lamoureux EL, Seah LL.

Transl Vis Sci Technol. 2018 Oct 1;7(5):14. doi: 10.1167/tvst.7.5.14. eCollection 2018 Sep.


Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis.

Lueschow SR, Stumphy J, Gong H, Kern SL, Elgin TG, Underwood MA, Kalanetra KM, Mills DA, Wong MH, Meyerholz DK, Good M, McElroy SJ.

PLoS One. 2018 Oct 1;13(10):e0204967. doi: 10.1371/journal.pone.0204967. eCollection 2018.


Mechanism and Implication of the Sorption of Perfluorooctanoic Acid by Varying Soil Size Fractions.

Xiang L, Xiao T, Yu PF, Zhao HM, Mo CH, Li YW, Li H, Cai QY, Zhou DM, Wong MH.

J Agric Food Chem. 2018 Nov 7;66(44):11569-11579. doi: 10.1021/acs.jafc.8b03492. Epub 2018 Oct 26.


MiR-486-5p Downregulation Marks an Early Event in Colorectal Carcinogenesis.

Kelley KA, Wieghard N, Chin Y, Potter A, Mori M, Wong MH, Chin K, Tsikitis VL.

Dis Colon Rectum. 2018 Nov;61(11):1290-1296. doi: 10.1097/DCR.0000000000001192.


Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival.

Gast CE, Silk AD, Zarour L, Riegler L, Burkhart JG, Gustafson KT, Parappilly MS, Roh-Johnson M, Goodman JR, Olson B, Schmidt M, Swain JR, Davies PS, Shasthri V, Iizuka S, Flynn P, Watson S, Korkola J, Courtneidge SA, Fischer JM, Jaboin J, Billingsley KG, Lopez CD, Burchard J, Gray J, Coussens LM, Sheppard BC, Wong MH.

Sci Adv. 2018 Sep 12;4(9):eaat7828. doi: 10.1126/sciadv.aat7828. eCollection 2018 Sep.


Rational Design Principles for the Transport and Subcellular Distribution of Nanomaterials into Plant Protoplasts.

Lew TTS, Wong MH, Kwak SY, Sinclair R, Koman VB, Strano MS.

Small. 2018 Nov;14(44):e1802086. doi: 10.1002/smll.201802086. Epub 2018 Sep 6.


Variations in microbial community and di-(2-ethylhexyl) phthalate (DEHP) dissipation in different rhizospheric compartments between low- and high-DEHP accumulating cultivars of rice (Oryza sativa L.).

Chen XX, Wu Y, Huang XP, Lü H, Zhao HM, Mo CH, Li H, Cai QY, Wong MH.

Ecotoxicol Environ Saf. 2018 Nov 15;163:567-576. doi: 10.1016/j.ecoenv.2018.07.097. Epub 2018 Aug 1.


Arbuscular mycorrhizal fungal community in the topsoil of a subtropical landfill restored after 18 years.

Chen XW, Wong JTF, Chen ZT, Leung AOW, Ng CWW, Wong MH.

J Environ Manage. 2018 Nov 1;225:17-24. doi: 10.1016/j.jenvman.2018.07.068. Epub 2018 Jul 30.


SAP102 regulates synaptic AMPAR function through a CNIH-2-dependent mechanism.

Liu M, Shi R, Hwang H, Han KS, Wong MH, Ren X, Lewis LD, Brown EN, Xu W.

J Neurophysiol. 2018 Oct 1;120(4):1578-1586. doi: 10.1152/jn.00731.2017. Epub 2018 Aug 1.


Feeding and metabolism effects of three common microplastics on Tenebrio molitor L.

Wu Q, Tao H, Wong MH.

Environ Geochem Health. 2019 Feb;41(1):17-26. doi: 10.1007/s10653-018-0161-5. Epub 2018 Jul 28.


Biodegradation of di-butyl phthalate (DBP) by a novel endophytic bacterium Bacillus subtilis and its bioaugmentation for removing DBP from vegetation slurry.

Huang YH, Huang XJ, Chen XH, Cai QY, Chen S, Mo CH, Lü H, Wong MH.

J Environ Manage. 2018 Oct 15;224:1-9. doi: 10.1016/j.jenvman.2018.07.023. Epub 2018 Jul 11.


ASK1 contributes to fibrosis and dysfunction in models of kidney disease.

Liles JT, Corkey BK, Notte GT, Budas GR, Lansdon EB, Hinojosa-Kirschenbaum F, Badal SS, Lee M, Schultz BE, Wise S, Pendem S, Graupe M, Castonguay L, Koch KA, Wong MH, Papalia GA, French DM, Sullivan T, Huntzicker EG, Ma FY, Nikolic-Paterson DJ, Altuhaifi T, Yang H, Fogo AB, Breckenridge DG.

J Clin Invest. 2018 Oct 1;128(10):4485-4500. doi: 10.1172/JCI99768. Epub 2018 Jul 19.


Biodegradation pathway of di-(2-ethylhexyl) phthalate by a novel Rhodococcus pyridinivorans XB and its bioaugmentation for remediation of DEHP contaminated soil.

Zhao HM, Hu RW, Chen XX, Chen XB, Lü H, Li YW, Li H, Mo CH, Cai QY, Wong MH.

Sci Total Environ. 2018 Nov 1;640-641:1121-1131. doi: 10.1016/j.scitotenv.2018.05.334. Epub 2018 Jun 7.


Comparison of sorption kinetics of PAHs by sorptive sinks and caco-2 cell and the correlation between bioaccessibility and bioavailability of PAHs in indoor dust.

Kang Y, Zeng D, Man YB, Liu J, Yang Y, Li S, Situ K, Xiong W, Zeng L, Zhang Q, Luo J, Pan W, Jiang F, Wong MH.

Sci Total Environ. 2018 Dec 15;645:170-178. doi: 10.1016/j.scitotenv.2018.07.102. Epub 2018 Jul 17.


Long-term safety and treatment effects of cannabidiol in children and adults with treatment-resistant epilepsies: Expanded access program results.

Szaflarski JP, Bebin EM, Comi AM, Patel AD, Joshi C, Checketts D, Beal JC, Laux LC, De Boer LM, Wong MH, Lopez M, Devinsky O, Lyons PD, Zentil PP, Wechsler R; CBD EAP study group.

Epilepsia. 2018 Aug;59(8):1540-1548. doi: 10.1111/epi.14477. Epub 2018 Jul 12.


Special issue: bioremediation of contaminated soil and water: GeoTrop 2017.

Tsang YF, Ok YS, Sarmah AK, Cao B, Wong MH.

Biodegradation. 2018 Aug;29(4):311-312. doi: 10.1007/s10532-018-9842-0. No abstract available.


Discovery of rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer.

Shi X, Li H, Shi A, Yao H, Ke K, Dong C, Zhu Y, Qin Y, Ding Y, He YH, Liu X, Li L, Lei L, Hai Q, Chen W, Leung KS, Wong MH, Kung HF, Lin MC.

Oncol Rep. 2018 Sep;40(3):1592-1600. doi: 10.3892/or.2018.6533. Epub 2018 Jun 27.


Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations.

Smith NR, Swain JR, Davies PS, Gallagher AC, Parappilly MS, Beach CZ, Streeter PR, Williamson IA, Magness ST, Wong MH.

Cell Mol Gastroenterol Hepatol. 2018 Mar 10;6(1):79-96. doi: 10.1016/j.jcmgh.2018.02.007. eCollection 2018.


Background levels of methane in Mars' atmosphere show strong seasonal variations.

Webster CR, Mahaffy PR, Atreya SK, Moores JE, Flesch GJ, Malespin C, McKay CP, Martinez G, Smith CL, Martin-Torres J, Gomez-Elvira J, Zorzano MP, Wong MH, Trainer MG, Steele A, Archer D Jr, Sutter B, Coll PJ, Freissinet C, Meslin PY, Gough RV, House CH, Pavlov A, Eigenbrode JL, Glavin DP, Pearson JC, Keymeulen D, Christensen LE, Schwenzer SP, Navarro-Gonzalez R, Pla-García J, Rafkin SCR, Vicente-Retortillo Á, Kahanpää H, Viudez-Moreiras D, Smith MD, Harri AM, Genzer M, Hassler DM, Lemmon M, Crisp J, Sander SP, Zurek RW, Vasavada AR.

Science. 2018 Jun 8;360(6393):1093-1096. doi: 10.1126/science.aaq0131.


Functional genomic analysis of phthalate acid ester (PAE) catabolism genes in the versatile PAE-mineralising bacterium Rhodococcus sp. 2G.

Zhao HM, Hu RW, Du H, Xin XP, Li YW, Li H, Cai QY, Mo CH, Liu JS, Zhou DM, Wong MH, He ZL.

Sci Total Environ. 2018 Nov 1;640-641:646-652. doi: 10.1016/j.scitotenv.2018.05.337. Epub 2018 Jun 2.


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