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Items: 1 to 50 of 286


Application of a Common Data Model (CDM) to rank the paediatric user and prescription prevalence of 15 different drug classes in South Korea, Hong Kong, Taiwan, Japan and Australia: an observational, descriptive study.

Brauer R, Wong ICK, Man KK, Pratt NL, Park RW, Cho SY, Li YJ, Iqbal U, Nguyen PA, Schuemie M.

BMJ Open. 2020 Jan 13;10(1):e032426. doi: 10.1136/bmjopen-2019-032426.


Oral Anticoagulant and Reduced Risk of Dementia in Patients with Atrial Fibrillation: A Population-Based Cohort Study.

Mongkhon P, Fanning L, Lau WCY, Tse G, Lau KK, Wei L, Kongkaew C, Wong ICK.

Heart Rhythm. 2020 Jan 10. pii: S1547-5271(20)30011-4. doi: 10.1016/j.hrthm.2020.01.007. [Epub ahead of print]


Mortality Among Children with Down syndrome in Hong Kong: A Population-Based Cohort Study from Birth.

Chua GT, Tung KTS, Wong ICK, Lum TYS, Wong WHS, Chow CB, Ho FK, Wong RS, Ip P.

J Pediatr. 2020 Jan 9. pii: S0022-3476(19)31514-8. doi: 10.1016/j.jpeds.2019.11.006. [Epub ahead of print]


Safety and Effectiveness of Direct Oral Anticoagulants vs Warfarin in People With Atrial Fibrillation and Dementia.

Fanning L, Lau WCY, Mongkhon P, Man KKC, Bell JS, Ilomäki J, Dārziņš P, Lau KK, Wei L, Wong ICK.

J Am Med Dir Assoc. 2020 Jan 6. pii: S1525-8610(19)30831-X. doi: 10.1016/j.jamda.2019.11.022. [Epub ahead of print]


Mortality Risk Associated with Haloperidol Use Compared with Other Antipsychotics: An 11-Year Population-Based Propensity-Score-Matched Cohort Study.

Lao KSJ, Wong AYS, Wong ICK, Besag FMC, Chang WC, Lee EHM, Chen EYH, Blais JE, Chan EW.

CNS Drugs. 2020 Jan 8. doi: 10.1007/s40263-019-00693-5. [Epub ahead of print]


Comparative cardiovascular risk in users versus non-users of xanthine oxidase inhibitors and febuxostat versus allopurinol users.

Ju C, Lai RWC, Li KHC, Hung JKF, Lai JCL, Ho J, Liu Y, Tsoi MF, Liu T, Cheung BMY, Wong ICK, Tam LS, Tse G.

Rheumatology (Oxford). 2019 Dec 24. pii: kez576. doi: 10.1093/rheumatology/kez576. [Epub ahead of print]


Statins were associated with a reduced gastric cancer risk in patients with eradicated Helicobacter pylori infection: a territory-wide propensity score matched study.

Cheung KS, Chan EW, Wong AY, Chen L, Seto WK, Wong IC, Leung WK.

Cancer Epidemiol Biomarkers Prev. 2019 Dec 2. pii: cebp.1044.2019. doi: 10.1158/1055-9965.EPI-19-1044. [Epub ahead of print]


Psychotropic Medication Prescribing for Neuropsychiatric Comorbidities in Individuals Diagnosed with Autism Spectrum Disorder (ASD) in the UK.

Alfageh BH, Man KKC, Besag FMC, Alhawassi TM, Wong ICK, Brauer R.

J Autism Dev Disord. 2019 Nov 13. doi: 10.1007/s10803-019-04291-8. [Epub ahead of print]


Adverse Events Associated with Melatonin for the Treatment of Primary or Secondary Sleep Disorders: A Systematic Review.

Besag FMC, Vasey MJ, Lao KSJ, Wong ICK.

CNS Drugs. 2019 Dec;33(12):1167-1186. doi: 10.1007/s40263-019-00680-w. Review.


A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service.

Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos CA, Lumbers RT, Mathur R, Sofat R, Casas JP, Wong ICK, Hemingway H, Hingorani AD.

Lancet Digit Health. 2019 May 20;1(2):e63-e77. doi: 10.1016/S2589-7500(19)30012-3. eCollection 2019 Jun.


Attitudes and perceptions towards hypoglycaemia in patients with diabetes mellitus: A multinational cross-sectional study.

Naser AY, Wong ICK, Whittlesea C, Alwafi H, Abuirmeileh A, Alsairafi ZK, Turkistani FM, Bokhari NS, Beykloo MY, Al-Taweel D, Almane MB, Wei L.

PLoS One. 2019 Oct 24;14(10):e0222275. doi: 10.1371/journal.pone.0222275. eCollection 2019.


Risks of hospitalization for upper gastrointestinal bleeding in users of selective serotonin reuptake inhibitors after Helicobacter pylori eradication therapy: a propensity score matching analysis.

Guo CG, Cheung KS, Zhang F, Chan EW, Chen L, Wong ICK, Leung WK.

Aliment Pharmacol Ther. 2019 Nov;50(9):1001-1008. doi: 10.1111/apt.15507. Epub 2019 Oct 3.


Neurological and psychiatric adverse effects of long-term methylphenidate treatment in ADHD: A map of the current evidence.

Krinzinger H, Hall CL, Groom MJ, Ansari MT, Banaschewski T, Buitelaar JK, Carucci S, Coghill D, Danckaerts M, Dittmann RW, Falissard B, Garas P, Inglis SK, Kovshoff H, Kochhar P, McCarthy S, Nagy P, Neubert A, Roberts S, Sayal K, Sonuga-Barke E, Wong ICK, Xia J, Zuddas A, Hollis C, Konrad K, Liddle EB; ADDUCE Consortium.

Neurosci Biobehav Rev. 2019 Dec;107:945-968. doi: 10.1016/j.neubiorev.2019.09.023. Epub 2019 Sep 20. Review.


Survey on self-reported psychotropic drug prescribing practices of eating disorder psychiatrists for the treatment of young people with anorexia nervosa.

Y Beykloo M, Nicholls D, Simic M, Brauer R, Mills E, Wong ICK.

BMJ Open. 2019 Sep 20;9(9):e031707. doi: 10.1136/bmjopen-2019-031707.


Prevalence, Safety, and Effectiveness of Oral Anticoagulant Use in People with and without Dementia or Cognitive Impairment: A Systematic Review and Meta-Analysis.

Fanning L, Ryan-Atwood TE, Bell JS, Meretoja A, McNamara KP, Dārziņš P, Wong ICK, Ilomäki J.

J Alzheimers Dis. 2019;71(4):1375-1378. doi: 10.3233/JAD-199005. No abstract available.


A plea to stop using the case-control design in retrospective database studies.

Schuemie MJ, Ryan PB, Man KKC, Wong ICK, Suchard MA, Hripcsak G.

Stat Med. 2019 Sep 30;38(22):4199-4208. doi: 10.1002/sim.8215. Epub 2019 Aug 22.


Thromboembolic, bleeding, and mortality risks among patients with nonvalvular atrial fibrillation treated with dual antiplatelet therapy versus oral anticoagulants: A population-based study.

Lau WCY, Douglas IJ, Wong ICK, Smeeth L, Lip GYH, Leung WK, Siu CW, Cheung BMY, Mok MTC, Chan EW.

Heart Rhythm. 2020 Jan;17(1):33-40. doi: 10.1016/j.hrthm.2019.07.034. Epub 2019 Aug 1.


Vitamin K Antagonist Use and Fracture.

Lau WCY, Man KKC, Wong ICK.

J Gen Intern Med. 2020 Jan;35(1):396-397. doi: 10.1007/s11606-019-05185-2. No abstract available.


Positive effects of low LDL-C and statins on bone mineral density: an integrated epidemiological observation analysis and Mendelian randomization study.

Li GH, Cheung CL, Au PC, Tan KC, Wong IC, Sham PC.

Int J Epidemiol. 2019 Jul 13. pii: dyz145. doi: 10.1093/ije/dyz145. [Epub ahead of print]


Diabetes Increases Risk of Gastric Cancer After Helicobacter pylori Eradication: A Territory-Wide Study With Propensity Score Analysis.

Cheung KS, Chan EW, Chen L, Seto WK, Wong ICK, Leung WK.

Diabetes Care. 2019 Sep;42(9):1769-1775. doi: 10.2337/dc19-0437. Epub 2019 Jul 11.


Budget impact of introducing tofacitinib to the public hospital formulary in Hong Kong, 2017-2021.

Li X, Pathadka S, Man KK, Wong ICK, Chan EWY.

Hong Kong Med J. 2019 Jun;25(3):201-208. doi: 10.12809/hkmj187673. Epub 2019 May 29.


Prevalence, Safety and Long-Term Retention Rates of Biologics in Hong Kong from 2001 to 2015.

Ge M, Man KK, Chui CS, Chan EW, Wong IC, Li X.

Drug Saf. 2019 Sep;42(9):1091-1102. doi: 10.1007/s40264-019-00844-z.


Safety and Tolerability of Antipsychotic Medication in Individuals with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis.

Alfageh BH, Wang Z, Mongkhon P, Besag FMC, Alhawassi TM, Brauer R, Wong ICK.

Paediatr Drugs. 2019 Jun;21(3):153-167. doi: 10.1007/s40272-019-00333-x.


Emerging challenges in pharmacotherapy research on attention-deficit hyperactivity disorder-outcome measures beyond symptom control and clinical trials.

Wong ICK, Banaschewski T, Buitelaar J, Cortese S, Döpfner M, Simonoff E, Coghill D; European ADHD Guidelines Group.

Lancet Psychiatry. 2019 Jun;6(6):528-537. doi: 10.1016/S2215-0366(19)30096-3. Review.


Incidences, temporal trends and risks of hospitalisation for gastrointestinal bleeding in new or chronic low-dose aspirin users after treatment for Helicobacter pylori: a territory-wide cohort study.

Guo CG, Cheung KS, Zhang F, Chan EW, Chen L, Wong IC, Leung WK.

Gut. 2019 May 17. pii: gutjnl-2019-318352. doi: 10.1136/gutjnl-2019-318352. [Epub ahead of print]


Early origins of oral penicillin dosing for children.

Sharland E, Long P, Sharland M, Bielicki J, Saxena S, Wong ICK, Barker C.

Arch Dis Child. 2019 Apr 17. pii: archdischild-2018-316531. doi: 10.1136/archdischild-2018-316531. [Epub ahead of print] No abstract available.


All-cause pneumonia in children after the introduction of pneumococcal vaccines in the United Kingdom: A population-based study.

Lau WCY, Bielicki J, Tersigni C, Saxena S, Wong ICK, Sharland M, Hsia Y.

Pharmacoepidemiol Drug Saf. 2019 Jun;28(6):821-829. doi: 10.1002/pds.4770. Epub 2019 Apr 16.


Patient factors and their impact on neutropenic events: a systematic review and meta-analysis.

Chambers P, Jani Y, Wei L, Kipps E, Forster MD, Wong ICK.

Support Care Cancer. 2019 Jul;27(7):2413-2424. doi: 10.1007/s00520-019-04773-6. Epub 2019 Apr 16.


Risk factors for drug allergies in Chinese children.

Duque JSR, Cheuk DK, Chong PC, Ip P, Wong WH, Lee PP, Wong IC, Chan GC, Lau YL, Ho MH.

Asian Pac J Allergy Immunol. 2019 Mar 24. doi: 10.12932/AP-191018-0417. [Epub ahead of print]


Estimating global trends in total and childhood antibiotic consumption, 2011-2015.

Jackson C, Hsia Y, Bielicki JA, Ellis S, Stephens P, Wong ICK, Sharland M.

BMJ Glob Health. 2019 Feb 27;4(1):e001241. doi: 10.1136/bmjgh-2018-001241. eCollection 2019.


Statins reduce the progression of non-advanced adenomas to colorectal cancer: a postcolonoscopy study in 187 897 patients.

Cheung KS, Chen L, Chan EW, Seto WK, Wong ICK, Leung WK.

Gut. 2019 Nov;68(11):1979-1985. doi: 10.1136/gutjnl-2018-317714. Epub 2019 Feb 26.


Oral chloral hydrate versus intranasal dexmedetomidine for sedation of children undergoing computed tomography: a multicentre study.

Yuen VM, Cheuk DK, Hui TW, Wong IC, Lam WW, Irwin MG.

Hong Kong Med J. 2019 Feb;25 Suppl 3(1):27-29. No abstract available.


Bone mineral density from early to middle adulthood in persons with Down syndrome.

Tang JYM, Luo H, Wong GHY, Lau MMY, Joe GM, Tse MA, Ip P, Wong ICK, Lum TYS.

J Intellect Disabil Res. 2019 Aug;63(8):936-946. doi: 10.1111/jir.12608. Epub 2019 Feb 18.


Trazodone use and risk of dementia: A population-based cohort study.

Brauer R, Lau WCY, Hayes JF, Man KKC, Osborn DPJ, Howard R, Kim J, Wong ICK.

PLoS Med. 2019 Feb 5;16(2):e1002728. doi: 10.1371/journal.pmed.1002728. eCollection 2019 Feb.


Population-based estimates of the burden of pneumonia hospitalizations in Hong Kong, 2011-2015.

Li X, Blais JE, Wong ICK, Tam AWY, Cowling BJ, Hung IFN, Chan EWY.

Eur J Clin Microbiol Infect Dis. 2019 Mar;38(3):553-561. doi: 10.1007/s10096-018-03459-x. Epub 2019 Jan 25.


Early sleep deprivation and attention-deficit/hyperactivity disorder.

Tso W, Chan M, Ho FK, Rao N, Li AM, Chan KL, Tiwari A, Wong ICK, Wing YK, Van Voorhees B, Li SL, Goh WHS, Ip P.

Pediatr Res. 2019 Mar;85(4):449-455. doi: 10.1038/s41390-019-0280-4. Epub 2019 Jan 17.


Effect of evidence-based therapy for secondary prevention of cardiovascular disease: Systematic review and meta-analysis.

Ma TT, Wong ICK, Man KKC, Chen Y, Crake T, Ozkor MA, Ding LQ, Wang ZX, Zhang L, Wei L.

PLoS One. 2019 Jan 18;14(1):e0210988. doi: 10.1371/journal.pone.0210988. eCollection 2019.


Consumption of oral antibiotic formulations for young children according to the WHO Access, Watch, Reserve (AWaRe) antibiotic groups: an analysis of sales data from 70 middle-income and high-income countries.

Hsia Y, Sharland M, Jackson C, Wong ICK, Magrini N, Bielicki JA.

Lancet Infect Dis. 2019 Jan;19(1):67-75. doi: 10.1016/S1473-3099(18)30547-4. Epub 2018 Dec 3.


Penetration of new antidiabetic medications in East Asian countries and the United States: A cross-national comparative study.

Kubota K, Kamijima Y, Kao Yang YH, Kimura S, Chia-Cheng Lai E, Man KKC, Ryan P, Schuemie M, Stang P, Su CC, Wong ICK, Zhang Y, Setoguchi S.

PLoS One. 2018 Dec 12;13(12):e0208796. doi: 10.1371/journal.pone.0208796. eCollection 2018.


Trends in statin prescription prevalence, initiation, and dosing: Hong Kong, 2004-2015.

Blais JE, Chan EW, Law SWY, Mok MT, Huang D, Wong ICK, Siu CW.

Atherosclerosis. 2019 Jan;280:174-182. doi: 10.1016/j.atherosclerosis.2018.11.015. Epub 2018 Nov 10.


Systematic review with meta-analysis: the risk of gastrointestinal bleeding in patients taking third-generation P2Y12 inhibitors compared with clopidogrel.

Guo CG, Chen L, Chan EW, Cheung KS, Isshiki T, Wong ICK, Leung WK.

Aliment Pharmacol Ther. 2019 Jan;49(1):7-19. doi: 10.1111/apt.15059. Epub 2018 Dec 2.


Use of multiple antidiabetic medications in patients with diabetes and its association with hypoglycaemic events: a case-crossover study in Jordan.

Naser AY, Wong ICK, Whittlesea C, Beykloo MY, Man KKC, Lau WCY, Hyassat DA, Wei L.

BMJ Open. 2018 Nov 21;8(11):e024909. doi: 10.1136/bmjopen-2018-024909.


Reply: Sex-Based Differences in Outcomes of Oral Anticoagulation: Does Antiplatelet Therapy Matter?

Law SWY, Lau WCY, Wong ICK, Chan EW.

J Am Coll Cardiol. 2018 Nov 13;72(20):2547-2548. doi: 10.1016/j.jacc.2018.09.023. No abstract available.


Associations between the LEP -2548G/A Promoter and Baseline Weight and between LEPR Gln223Arg and Lys656Asn Variants and Change in BMI z Scores in Arab Children and Adolescents Treated with Risperidone.

Almandil NB, Lodhi RJ, Ren H, Besag FMC, Rossolatos D, Ohlsen R, Slomp C, Lapetina DL, Plazzotta G, Murray ML, Al-Sulaiman AA, Gringras P, Wong ICK, Aitchison KJ.

Mol Neuropsychiatry. 2018 Oct;4(2):111-117. doi: 10.1159/000490463. Epub 2018 Oct 5.


Oral anticoagulants and risk of dementia: A systematic review and meta-analysis of observational studies and randomized controlled trials.

Mongkhon P, Naser AY, Fanning L, Tse G, Lau WCY, Wong ICK, Kongkaew C.

Neurosci Biobehav Rev. 2019 Jan;96:1-9. doi: 10.1016/j.neubiorev.2018.10.025. Epub 2018 Nov 2.


Metformin Use and Gastric Cancer Risk in Diabetic Patients After Helicobacter pylori Eradication.

Cheung KS, Chan EW, Wong AYS, Chen L, Seto WK, Wong ICK, Leung WK.

J Natl Cancer Inst. 2019 May 1;111(5):484-489. doi: 10.1093/jnci/djy144.


Effects of long-term methylphenidate use on growth and blood pressure: results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS).

McCarthy S, Neubert A, Man KKC, Banaschewski T, Buitelaar J, Carucci S, Coghill D, Danckaerts M, Falissard B, Garas P, Häge A, Hollis C, Inglis S, Kovshoff H, Liddle E, Mechler K, Nagy P, Rosenthal E, Schlack R, Sonuga-Barke E, Zuddas A, Wong ICK.

BMC Psychiatry. 2018 Oct 11;18(1):327. doi: 10.1186/s12888-018-1884-7.

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