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Application of a Common Data Model (CDM) to rank the paediatric user and prescription prevalence of 15 different drug classes in South Korea, Hong Kong, Taiwan, Japan and Australia: an observational, descriptive study.

Brauer R, Wong ICK, Man KK, Pratt NL, Park RW, Cho SY, Li YJ, Iqbal U, Nguyen PA, Schuemie M.

BMJ Open. 2020 Jan 13;10(1):e032426. doi: 10.1136/bmjopen-2019-032426.


Oral Anticoagulant and Reduced Risk of Dementia in Patients with Atrial Fibrillation: A Population-Based Cohort Study.

Mongkhon P, Fanning L, Lau WCY, Tse G, Lau KK, Wei L, Kongkaew C, Wong ICK.

Heart Rhythm. 2020 Jan 10. pii: S1547-5271(20)30011-4. doi: 10.1016/j.hrthm.2020.01.007. [Epub ahead of print]


LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate.

Gao Y, Yan Y, Tripathi S, Pentinmikko N, Amaral A, Päivinen P, Domènech-Moreno E, Andersson S, Wong IPL, Clevers H, Katajisto P, Mäkelä TP.

Gastroenterology. 2020 Jan 10. pii: S0016-5085(20)30072-X. doi: 10.1053/j.gastro.2019.12.033. [Epub ahead of print]


Mortality Among Children with Down syndrome in Hong Kong: A Population-Based Cohort Study from Birth.

Chua GT, Tung KTS, Wong ICK, Lum TYS, Wong WHS, Chow CB, Ho FK, Wong RS, Ip P.

J Pediatr. 2020 Jan 9. pii: S0022-3476(19)31514-8. doi: 10.1016/j.jpeds.2019.11.006. [Epub ahead of print]


Safety and Effectiveness of Direct Oral Anticoagulants vs Warfarin in People With Atrial Fibrillation and Dementia.

Fanning L, Lau WCY, Mongkhon P, Man KKC, Bell JS, Ilomäki J, Dārziņš P, Lau KK, Wei L, Wong ICK.

J Am Med Dir Assoc. 2020 Jan 6. pii: S1525-8610(19)30831-X. doi: 10.1016/j.jamda.2019.11.022. [Epub ahead of print]


Mortality Risk Associated with Haloperidol Use Compared with Other Antipsychotics: An 11-Year Population-Based Propensity-Score-Matched Cohort Study.

Lao KSJ, Wong AYS, Wong ICK, Besag FMC, Chang WC, Lee EHM, Chen EYH, Blais JE, Chan EW.

CNS Drugs. 2020 Jan 8. doi: 10.1007/s40263-019-00693-5. [Epub ahead of print]


Supine heart rate measurement in elderly Chinese.

Wong IGY, Woo BKP.

J Hypertens. 2020 Feb;38(2):368. doi: 10.1097/HJH.0000000000002268. No abstract available.


A trial protocol for the effectiveness of digital interventions for preventing depression in adolescents: The Future Proofing Study.

Werner-Seidler A, Huckvale K, Larsen ME, Calear AL, Maston K, Johnston L, Torok M, O'Dea B, Batterham PJ, Schweizer S, Skinner SR, Steinbeck K, Ratcliffe J, Oei JL, Patton G, Wong I, Beames J, Wong QJJ, Lingam R, Boydell K, Salmon AM, Cockayne N, Mackinnon A, Christensen H.

Trials. 2020 Jan 2;21(1):2. doi: 10.1186/s13063-019-3901-7.


Posterior Glenohumeral Capsular Reconstruction With Modified McLaughlin for Chronic Locked Posterior Dislocation.

Matthewson G, Wong IH.

Arthrosc Tech. 2019 Nov 22;8(12):e1543-e1550. doi: 10.1016/j.eats.2019.08.004. eCollection 2019 Dec.


Arthroscopic Revision with Autologous Iliac Crest Bone Graft for Failed Anatomic Glenoid Reconstruction Using Distal Tibia Allograft.

John R, Coady CM, Wong I.

Arthrosc Tech. 2019 Oct 11;8(11):e1333-e1338. doi: 10.1016/j.eats.2019.07.009. eCollection 2019 Nov.


Hip Arthroscopy for Femoral Acetabular Impingement: A Bird's-Eye/En Face Perspective With Ultrasound Guidance and 3-Dimensional Hip Printing.

Ali MI, Ravipati APT, Wong I.

Arthrosc Tech. 2019 Oct 7;8(11):e1301-e1307. doi: 10.1016/j.eats.2019.07.004. eCollection 2019 Nov.


Improving the current diabetic macular oedema screening programme.

Wong I, Wong R, Gangwani R, Chong V, Kawasaki R.

Hong Kong Med J. 2019 Dec;25 Suppl 9(6):8-11. No abstract available.


Comparative cardiovascular risk in users versus non-users of xanthine oxidase inhibitors and febuxostat versus allopurinol users.

Ju C, Lai RWC, Li KHC, Hung JKF, Lai JCL, Ho J, Liu Y, Tsoi MF, Liu T, Cheung BMY, Wong ICK, Tam LS, Tse G.

Rheumatology (Oxford). 2019 Dec 24. pii: kez576. doi: 10.1093/rheumatology/kez576. [Epub ahead of print]


The Fml1-MHF complex suppresses inter-fork strand annealing in fission yeast.

Wong IN, Neo JP, Oehler J, Schafhauser S, Osman F, Carr SB, Whitby MC.

Elife. 2019 Dec 19;8. pii: e49784. doi: 10.7554/eLife.49784.


Statins were associated with a reduced gastric cancer risk in patients with eradicated Helicobacter pylori infection: a territory-wide propensity score matched study.

Cheung KS, Chan EW, Wong AY, Chen L, Seto WK, Wong IC, Leung WK.

Cancer Epidemiol Biomarkers Prev. 2019 Dec 2. pii: cebp.1044.2019. doi: 10.1158/1055-9965.EPI-19-1044. [Epub ahead of print]


Editorial Commentary: Dermal Allograft: A Viable Allograft for Salvage Procedures in Treating Irreparable Rotator Cuff Tears.

Ravipati APT, Wong I.

Arthroscopy. 2019 Dec;35(12):3203-3204. doi: 10.1016/j.arthro.2019.08.020.


Exophthalmometry values in the Hong Kong Chinese adult population from a population-based study.

Cheung JJC, Chang DL, Chan JC, Choy BNK, Shih KC, Wong JKW, Ng ALK, Shum JWH, Ni MY, Lai JSM, Leung GM, Wong IYH.

Medicine (Baltimore). 2019 Nov;98(47):e17993. doi: 10.1097/MD.0000000000017993.


Macular Vessel Density Measured With Optical Coherence Tomography Angiography and Its Associations in a Large Population-Based Study.

You QS, Chan JCH, Ng ALK, Choy BKN, Shih KC, Cheung JJC, Wong JKW, Shum JWH, Ni MY, Lai JSM, Leung GM, Cheung CMG, Wong TY, Wong IYH.

Invest Ophthalmol Vis Sci. 2019 Nov 1;60(14):4830-4837. doi: 10.1167/iovs.19-28137.


The Reduction of Heterotopic Ossification Incidence After Hip Arthroscopy in Patients Treated With Selective Cyclooxygenase 2 Inhibitor (Celecoxib).

Dow T, King JP, Wong IH.

Arthroscopy. 2019 Nov 13. pii: S0749-8063(19)30754-6. doi: 10.1016/j.arthro.2019.08.034. [Epub ahead of print]


Psychotropic Medication Prescribing for Neuropsychiatric Comorbidities in Individuals Diagnosed with Autism Spectrum Disorder (ASD) in the UK.

Alfageh BH, Man KKC, Besag FMC, Alhawassi TM, Wong ICK, Brauer R.

J Autism Dev Disord. 2019 Nov 13. doi: 10.1007/s10803-019-04291-8. [Epub ahead of print]


Adverse Events Associated with Melatonin for the Treatment of Primary or Secondary Sleep Disorders: A Systematic Review.

Besag FMC, Vasey MJ, Lao KSJ, Wong ICK.

CNS Drugs. 2019 Dec;33(12):1167-1186. doi: 10.1007/s40263-019-00680-w. Review.


Illness representations among adolescents with attention deficit hyperactivity disorder: associations with quality of life, coping, and treatment adherence.

Wong IYT, Hawes DJ, Dar-Nimrod I.

Heliyon. 2019 Oct 23;5(10):e02705. doi: 10.1016/j.heliyon.2019.e02705. eCollection 2019 Oct.


A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service.

Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos CA, Lumbers RT, Mathur R, Sofat R, Casas JP, Wong ICK, Hemingway H, Hingorani AD.

Lancet Digit Health. 2019 May 20;1(2):e63-e77. doi: 10.1016/S2589-7500(19)30012-3. eCollection 2019 Jun.


Attitudes and perceptions towards hypoglycaemia in patients with diabetes mellitus: A multinational cross-sectional study.

Naser AY, Wong ICK, Whittlesea C, Alwafi H, Abuirmeileh A, Alsairafi ZK, Turkistani FM, Bokhari NS, Beykloo MY, Al-Taweel D, Almane MB, Wei L.

PLoS One. 2019 Oct 24;14(10):e0222275. doi: 10.1371/journal.pone.0222275. eCollection 2019.


Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma.

Chan KK, Wong ES, Wong IT, Cheung CL, Wong OG, Ngan HY, Cheung AN.

BMC Cancer. 2019 Oct 15;19(1):953. doi: 10.1186/s12885-019-6206-z.


Increase in omega-6 and decrease in omega-3 polyunsaturated fatty acid oxidation elevates the risk of exudative AMD development in adults with Chinese diet.

Leung HH, Ng AL, Durand T, Kawasaki R, Oger C, Balas L, Galano JM, Wong IY, Chung-Yung Lee J.

Free Radic Biol Med. 2019 Dec;145:349-356. doi: 10.1016/j.freeradbiomed.2019.10.007. Epub 2019 Oct 9.


Risks of hospitalization for upper gastrointestinal bleeding in users of selective serotonin reuptake inhibitors after Helicobacter pylori eradication therapy: a propensity score matching analysis.

Guo CG, Cheung KS, Zhang F, Chan EW, Chen L, Wong ICK, Leung WK.

Aliment Pharmacol Ther. 2019 Nov;50(9):1001-1008. doi: 10.1111/apt.15507. Epub 2019 Oct 3.


Neurological and psychiatric adverse effects of long-term methylphenidate treatment in ADHD: A map of the current evidence.

Krinzinger H, Hall CL, Groom MJ, Ansari MT, Banaschewski T, Buitelaar JK, Carucci S, Coghill D, Danckaerts M, Dittmann RW, Falissard B, Garas P, Inglis SK, Kovshoff H, Kochhar P, McCarthy S, Nagy P, Neubert A, Roberts S, Sayal K, Sonuga-Barke E, Wong ICK, Xia J, Zuddas A, Hollis C, Konrad K, Liddle EB; ADDUCE Consortium.

Neurosci Biobehav Rev. 2019 Dec;107:945-968. doi: 10.1016/j.neubiorev.2019.09.023. Epub 2019 Sep 20. Review.


Survey on self-reported psychotropic drug prescribing practices of eating disorder psychiatrists for the treatment of young people with anorexia nervosa.

Y Beykloo M, Nicholls D, Simic M, Brauer R, Mills E, Wong ICK.

BMJ Open. 2019 Sep 20;9(9):e031707. doi: 10.1136/bmjopen-2019-031707.


Prevalence, Safety, and Effectiveness of Oral Anticoagulant Use in People with and without Dementia or Cognitive Impairment: A Systematic Review and Meta-Analysis.

Fanning L, Ryan-Atwood TE, Bell JS, Meretoja A, McNamara KP, Dārziņš P, Wong ICK, Ilomäki J.

J Alzheimers Dis. 2019;71(4):1375-1378. doi: 10.3233/JAD-199005. No abstract available.


Breast Cancer Cells Transition from Mesenchymal to Amoeboid Migration in Tunable Three-Dimensional Silk-Collagen Hydrogels.

Khoo AS, Valentin TM, Leggett SE, Bhaskar D, Bye EM, Benmelech S, Ip BC, Wong IY.

ACS Biomater Sci Eng. 2019 Sep 9;5(9):4341-4354. doi: 10.1021/acsbiomaterials.9b00519. Epub 2019 Aug 14.


Triazole Bridged Flavonoid Dimers as Potent, Nontoxic, and Highly Selective Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibitors.

Zhu X, Wong ILK, Chan KF, Cui J, Law MC, Chong TC, Hu X, Chow LMC, Chan TH.

J Med Chem. 2019 Sep 26;62(18):8578-8608. doi: 10.1021/acs.jmedchem.9b00963. Epub 2019 Sep 12.


Mechanochemical engineering of 2D materials for multiscale biointerfaces.

Machnicki CE, Fu F, Jing L, Chen PY, Wong IY.

J Mater Chem B. 2019 Nov 7;7(41):6293-6309. doi: 10.1039/c9tb01006h. Epub 2019 Jul 10.


A plea to stop using the case-control design in retrospective database studies.

Schuemie MJ, Ryan PB, Man KKC, Wong ICK, Suchard MA, Hripcsak G.

Stat Med. 2019 Sep 30;38(22):4199-4208. doi: 10.1002/sim.8215. Epub 2019 Aug 22.


Motility-limited aggregation of mammary epithelial cells into fractal-like clusters.

Leggett SE, Neronha ZJ, Bhaskar D, Sim JY, Perdikari TM, Wong IY.

Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17298-17306. doi: 10.1073/pnas.1905958116. Epub 2019 Aug 14.


"Postage Stamp" Fractures: A Systematic Review of Patient and Suture Anchor Profiles Causing Anterior Glenoid Rim Fractures After Bankart Repair.

Woolnough T, Shah A, Sheean AJ, Lesniak BP, Wong I, de Sa D.

Arthroscopy. 2019 Aug;35(8):2501-2508.e2. doi: 10.1016/j.arthro.2019.02.047. Review.


Case control study of risk factors and ophthalmological outcomes of very low birth weight infants with Type 1 retinopathy of prematurity.

Ng T, Wong IB, Ngo CS, Niduvaje K, Ngiam XY, Sensaki S, Lee LY.

Singapore Med J. 2019 Aug 7. doi: 10.11622/smedj.2019095. [Epub ahead of print]


Genome-wide transcriptomic and proteomic studies of Rett syndrome mouse models identify common signaling pathways and cellular functions as potential therapeutic targets.

Krishnaraj R, Haase F, Coorey B, Luca EJ, Wong I, Boyling A, Ellaway C, Christodoulou J, Gold WA.

Hum Mutat. 2019 Dec;40(12):2184-2196. doi: 10.1002/humu.23887. Epub 2019 Aug 23. Review.


Reporting and guidelines for mendelian randomization analysis: A systematic review of oncological studies.

Lor GCY, Risch HA, Fung WT, Au Yeung SL, Wong IOL, Zheng W, Pang H.

Cancer Epidemiol. 2019 Oct;62:101577. doi: 10.1016/j.canep.2019.101577. Epub 2019 Aug 1. Review.


Thromboembolic, bleeding, and mortality risks among patients with nonvalvular atrial fibrillation treated with dual antiplatelet therapy versus oral anticoagulants: A population-based study.

Lau WCY, Douglas IJ, Wong ICK, Smeeth L, Lip GYH, Leung WK, Siu CW, Cheung BMY, Mok MTC, Chan EW.

Heart Rhythm. 2020 Jan;17(1):33-40. doi: 10.1016/j.hrthm.2019.07.034. Epub 2019 Aug 1.


Arthroscopy Association of Canada Position Statement on Intra-articular Injections for Knee Osteoarthritis.

Arthroscopy Association of Canada, Kopka M, Sheehan B, Degen R, Wong I, Hiemstra L, Ayeni O, Getgood A, Beavis C, Volesky M, Outerbridge R, Matache B.

Orthop J Sports Med. 2019 Jul 19;7(7):2325967119860110. doi: 10.1177/2325967119860110. eCollection 2019 Jul. No abstract available.


Barriers and facilitators experienced by patients, carers and healthcare professionals when managing symptoms in infants, children and young people at end-of-life: a mixed methods systematic review protocol.

Greenfield K, Holley S, Schoth DE, Harrop E, Howard R, Bayliss J, Brook L, Jassal S, Johnson M, Wong I, Liossi C.

BMJ Open. 2019 Jul 27;9(7):e030566. doi: 10.1136/bmjopen-2019-030566.


Dietary Habits, Fatty Acids and Carotenoid Levels Are Associated with Neovascular Age-Related Macular Degeneration in Chinese.

Ng AL, Leung HH, Kawasaki R, Ho WL, Chow LL, Chow SS, Lee JC, Wong IY.

Nutrients. 2019 Jul 25;11(8). pii: E1720. doi: 10.3390/nu11081720.


Vitamin K Antagonist Use and Fracture.

Lau WCY, Man KKC, Wong ICK.

J Gen Intern Med. 2020 Jan;35(1):396-397. doi: 10.1007/s11606-019-05185-2. No abstract available.


Innovative Approaches in the Management of Shoulder Instability: Current Concept Review.

John R, Wong I.

Curr Rev Musculoskelet Med. 2019 Jul 23:386-396. doi: 10.1007/s12178-019-09569-z. [Epub ahead of print] Review.


Positive effects of low LDL-C and statins on bone mineral density: an integrated epidemiological observation analysis and Mendelian randomization study.

Li GH, Cheung CL, Au PC, Tan KC, Wong IC, Sham PC.

Int J Epidemiol. 2019 Jul 13. pii: dyz145. doi: 10.1093/ije/dyz145. [Epub ahead of print]


Diabetes Increases Risk of Gastric Cancer After Helicobacter pylori Eradication: A Territory-Wide Study With Propensity Score Analysis.

Cheung KS, Chan EW, Chen L, Seto WK, Wong ICK, Leung WK.

Diabetes Care. 2019 Sep;42(9):1769-1775. doi: 10.2337/dc19-0437. Epub 2019 Jul 11.


Targeted delivery of antimicrobial peptide by Cry protein crystal to treat intramacrophage infection.

Yang Z, Zheng J, Chan CF, Wong ILK, Heater BS, Chow LMC, Lee MMM, Chan MK.

Biomaterials. 2019 Oct;217:119286. doi: 10.1016/j.biomaterials.2019.119286. Epub 2019 Jun 15.


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