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Items: 1 to 50 of 115

1.

Palliative Care Opportunities Among Adults With Congenital Heart Disease-A Systematic Review.

Ludmir J, Steiner JM, Wong HN, Kloosterboer A, Leong J, Aslakson RA.

J Pain Symptom Manage. 2019 Aug 9. pii: S0885-3924(19)30439-7. doi: 10.1016/j.jpainsymman.2019.07.025. [Epub ahead of print]

PMID:
31404639
2.

Correction to "Chiral Hydroxytetraphenylene-Catalyzed Asymmetric Conjugate Addition of Boronic Acids to Enones".

Chai GL, Sun AQ, Zhai D, Wang J, Deng WQ, Wong HNC, Chang J.

Org Lett. 2019 Aug 16;21(16):6584. doi: 10.1021/acs.orglett.9b02663. Epub 2019 Aug 8. No abstract available.

PMID:
31393131
3.

Chiral Hydroxytetraphenylene-Catalyzed Asymmetric Conjugate Addition of Boronic Acids to Enones.

Chai GL, Sun AQ, Zhai D, Wang J, Deng WQ, Wong HNC, Chang J.

Org Lett. 2019 Jul 5;21(13):5040-5045. doi: 10.1021/acs.orglett.9b01637. Epub 2019 Jun 19. Erratum in: Org Lett. 2019 Aug 16;21(16):6584.

PMID:
31247785
4.

Facile difluoromethylation of aliphatic alcohols with an S-(difluoro-methyl)sulfonium salt: reaction, scope and mechanistic study.

Liu GK, Li X, Qin WB, Peng XS, Wong HNC, Zhang L, Zhang X.

Chem Commun (Camb). 2019 Jul 4;55(52):7446-7449. doi: 10.1039/c9cc03487k. Epub 2019 Jun 5.

PMID:
31165809
5.

Efficacy and toxicity of particle radiotherapy in WHO grade II and grade III meningiomas: a systematic review.

Wu A, Jin MC, Meola A, Wong HN, Chang SD.

Neurosurg Focus. 2019 Jun 1;46(6):E12. doi: 10.3171/2019.3.FOCUS1967.

PMID:
31153145
6.

PtCl2-Catalyzed Cycloisomerization of 1,8-Enynes: Synthesis of Tetrahydropyridine Species.

Mirzaei A, Peng XS, Wong HNC.

Org Lett. 2019 May 17;21(10):3795-3798. doi: 10.1021/acs.orglett.9b01250. Epub 2019 May 1.

PMID:
31042044
7.

Patient-Reported Outcomes for Cancer Patients Receiving Checkpoint Inhibitors: Opportunities for Palliative Care-A Systematic Review.

Hall ET, Singhal S, Dickerson J, Gabster B, Wong HN, Aslakson RA, Schapira L; AAHPM Research Committee Writing Group.

J Pain Symptom Manage. 2019 Jul;58(1):137-156.e1. doi: 10.1016/j.jpainsymman.2019.03.015. Epub 2019 Mar 21.

PMID:
30905677
8.

Stereospecific Iron-Catalyzed Carbon(sp2)-Carbon(sp3) Cross-Coupling with Alkyllithium and Alkenyl Iodides.

Lu XL, Shannon M, Peng XS, Wong HNC.

Org Lett. 2019 Apr 19;21(8):2546-2549. doi: 10.1021/acs.orglett.9b00394. Epub 2019 Mar 12.

PMID:
30860388
9.

The evaluation of the anti-cancer drug elesclomol that forms a redox-active copper chelate as a potential anti-tubercular drug.

Ngwane AH, Petersen RD, Baker B, Wiid I, Wong HN, Haynes RK.

IUBMB Life. 2019 May;71(5):532-538. doi: 10.1002/iub.2002. Epub 2019 Jan 14.

PMID:
30698324
10.

Ligand-Free Iron-Catalyzed Carbon (sp2)-Carbon (sp2) Oxidative Homo-Coupling of Alkenyllithiums.

Zhong Z, Wang ZY, Ni SF, Dang L, Lee HK, Peng XS, Wong HNC.

Org Lett. 2019 Feb 1;21(3):700-704. doi: 10.1021/acs.orglett.8b03893. Epub 2019 Jan 24.

PMID:
30675791
11.

Chiral iminophosphorane catalyzed asymmetric sulfenylation of 4-substituted pyrazolones.

Han J, Zhang Y, Wu XY, Wong HNC.

Chem Commun (Camb). 2019 Jan 2;55(3):397-400. doi: 10.1039/c8cc09049a.

PMID:
30540301
12.

Air- and Light-Stable S-(Difluoromethyl)sulfonium Salts: C-Selective Electrophilic Difluoromethylation of β-Ketoesters and Malonates.

Lu SL, Li X, Qin WB, Liu JJ, Huang YY, Wong HNC, Liu GK.

Org Lett. 2018 Nov 2;20(21):6925-6929. doi: 10.1021/acs.orglett.8b03067. Epub 2018 Oct 12.

PMID:
30350647
13.

Synthesis, antimalarial activities and cytotoxicities of amino-artemisinin-1,2-disubstituted ferrocene hybrids.

de Lange C, Coertzen D, Smit FJ, Wentzel JF, Wong HN, Birkholtz LM, Haynes RK, N'Da DD.

Bioorg Med Chem Lett. 2018 Oct 15;28(19):3161-3163. doi: 10.1016/j.bmcl.2018.08.037. Epub 2018 Aug 28.

PMID:
30174153
14.

Facile Preparation of N-Glycosylated 10-Piperazinyl Artemisinin Derivatives and Evaluation of Their Antimalarial and Cytotoxic Activities.

Wu Y, Parapini S, Williams ID, Misiano P, Wong HN, Taramelli D, Basilico N, Haynes RK.

Molecules. 2018 Jul 13;23(7). pii: E1713. doi: 10.3390/molecules23071713.

15.

Gold(I)-Catalyzed Tandem Cycloisomerization of 1,5-Enyne Ethers by Hydride Transfer.

Lu XL, Lyu MY, Peng XS, Wong HNC.

Angew Chem Int Ed Engl. 2018 Aug 27;57(35):11365-11368. doi: 10.1002/anie.201806842. Epub 2018 Jul 24.

PMID:
29989283
16.

Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte Stages.

Coertzen D, Reader J, van der Watt M, Nondaba SH, Gibhard L, Wiesner L, Smith P, D'Alessandro S, Taramelli D, Wong HN, du Preez JL, Wu RWK, Birkholtz LM, Haynes RK.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e02214-17. doi: 10.1128/AAC.02214-17. Print 2018 Aug.

17.

Ligand-Free Iron-Catalyzed Carbon(sp2)-Carbon(sp2) Cross-Coupling of Alkenyllithium with Vinyl Halides.

Liu Q, Wang ZY, Peng XS, Wong HNC.

J Org Chem. 2018 Jun 15;83(12):6325-6333. doi: 10.1021/acs.joc.8b00510. Epub 2018 May 29.

PMID:
29790346
18.

Absorptive and Secretory Transport of Selected Artemisinin Derivatives Across Caco-2 Cell Monolayers.

Heyns J, Willers C, Haynes RK, Wong HN, Hamman J, Gouws C.

Curr Drug Deliv. 2018;15(8):1183-1192. doi: 10.2174/1567201815666180518125113.

PMID:
29779481
19.

The Artemisinin Derivative Artemisone Is a Potent Inhibitor of Human Cytomegalovirus Replication.

Oiknine-Djian E, Weisblum Y, Panet A, Wong HN, Haynes RK, Wolf DG.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e00288-18. doi: 10.1128/AAC.00288-18. Print 2018 Jul.

20.

Synthesis, in vitro antimalarial activities and cytotoxicities of amino-artemisinin-ferrocene derivatives.

de Lange C, Coertzen D, Smit FJ, Wentzel JF, Wong HN, Birkholtz LM, Haynes RK, N'Da DD.

Bioorg Med Chem Lett. 2018 Feb 1;28(3):289-292. doi: 10.1016/j.bmcl.2017.12.057. Epub 2017 Dec 26.

PMID:
29317166
21.

Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Asexual and Transmissible Malaria Parasites.

Harmse R, Coertzen D, Wong HN, Smit FJ, van der Watt ME, Reader J, Nondaba SH, Birkholtz LM, Haynes RK, N'Da DD.

ChemMedChem. 2017 Dec 19;12(24):2086-2093. doi: 10.1002/cmdc.201700599. Epub 2017 Dec 8.

PMID:
29219249
22.

Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Neospora caninum and Comparative Cytotoxicities.

Harmse R, Wong HN, Smit FJ, Müller J, Hemphill A, N'Da DD, Haynes RK.

ChemMedChem. 2017 Dec 19;12(24):2094-2098. doi: 10.1002/cmdc.201700600. Epub 2017 Dec 6.

PMID:
29210523
23.

Preliminary Evaluation of Artemisinin-Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis.

Morake M, Coertzen D, Ngwane A, Wentzel JF, Wong HN, Smit FJ, Birkholtz LM, Pietersen RD, Baker B, Wiid I, N'Da DD, Haynes RK.

ChemMedChem. 2018 Jan 8;13(1):67-77. doi: 10.1002/cmdc.201700579. Epub 2017 Dec 15.

PMID:
29193799
24.

Asymmetric Darzens Reaction of Isatins with Diazoacetamides Catalyzed by Chiral BINOL-Titanium Complex.

Chai GL, Han JW, Wong HNC.

J Org Chem. 2017 Dec 1;82(23):12647-12654. doi: 10.1021/acs.joc.7b02439. Epub 2017 Oct 31.

PMID:
29053263
25.

ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics.

Lin JS, Jeon JS, Fan Q, Wong HN, Palmer MB, Holzman LB.

PLoS One. 2017 Sep 7;12(9):e0184575. doi: 10.1371/journal.pone.0184575. eCollection 2017.

26.

Asymmetric Total Syntheses of Colchicine, β-Lumicolchicine, and Allocolchicinoid N-Acetylcolchinol-O-methyl Ether (NCME).

Liu X, Hu YJ, Chen B, Min L, Peng XS, Zhao J, Li S, Wong HNC, Li CC.

Org Lett. 2017 Sep 1;19(17):4612-4615. doi: 10.1021/acs.orglett.7b02224. Epub 2017 Aug 19.

PMID:
28823172
27.

Elimination of Schistosoma mansoni in infected mice by slow release of artemisone.

Gold D, Alian M, Domb A, Karawani Y, Jbarien M, Chollet J, Haynes RK, Wong HN, Buchholz V, Greiner A, Golenser J.

Int J Parasitol Drugs Drug Resist. 2017 Aug;7(2):241-247. doi: 10.1016/j.ijpddr.2017.05.002. Epub 2017 May 4.

28.

Leucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons.

Chen M, Geoffroy CG, Wong HN, Tress O, Nguyen MT, Holzman LB, Jin Y, Zheng B.

Sci Rep. 2016 Aug 11;6:31482. doi: 10.1038/srep31482.

29.

Corrigendum: Iron-catalysed cross-coupling of organolithium compounds with organic halides.

Jia Z, Liu Q, Peng XS, Wong HN.

Nat Commun. 2016 Jun 14;7:11955. doi: 10.1038/ncomms11955. No abstract available.

30.

Methylene Homologues of Artemisone: An Unexpected Structure-Activity Relationship and a Possible Implication for the Design of C10-Substituted Artemisinins.

Wu Y, Wu RW, Cheu KW, Williams ID, Krishna S, Slavic K, Gravett AM, Liu WM, Wong HN, Haynes RK.

ChemMedChem. 2016 Jul 5;11(13):1469-79. doi: 10.1002/cmdc.201600011. Epub 2016 Jun 7.

PMID:
27273875
31.

Correction to Total Synthesis of (±)-Gracilioether F.

Shen XY, Peng XS, Wong HN.

Org Lett. 2016 Apr 1;18(7):1711. doi: 10.1021/acs.orglett.6b00654. Epub 2016 Mar 16. No abstract available.

PMID:
26983071
32.

Repurposing of antiparasitic drugs: the hydroxy-naphthoquinone buparvaquone inhibits vertical transmission in the pregnant neosporosis mouse model.

Müller J, Aguado-Martínez A, Manser V, Wong HN, Haynes RK, Hemphill A.

Vet Res. 2016 Feb 17;47:32. doi: 10.1186/s13567-016-0317-1.

33.

Total Synthesis of (±)-Gracilioether F.

Shen XY, Peng XS, Wong HN.

Org Lett. 2016 Mar 4;18(5):1032-5. doi: 10.1021/acs.orglett.6b00161. Epub 2016 Feb 16. Erratum in: Org Lett. 2016 Apr 1;18(7):1711.

PMID:
26878903
34.

Iron-catalysed cross-coupling of organolithium compounds with organic halides.

Jia Z, Liu Q, Peng XS, Wong HN.

Nat Commun. 2016 Feb 5;7:10614. doi: 10.1038/ncomms10614. Erratum in: Nat Commun. 2016 Jun 14;7:11955.

35.

Synthesis and Chiroptical Properties of Double-Helical (M)- and (P)-o-Oligophenylenes.

Chen JX, Han JW, Wong HN.

Org Lett. 2015 Sep 4;17(17):4296-9. doi: 10.1021/acs.orglett.5b02102. Epub 2015 Aug 18.

PMID:
26284894
36.

The Case for Development of 11-Aza-artemisinins for Malaria.

Harmse R, Wong HN, Smit F, Haynes RK, N'Da DD.

Curr Med Chem. 2015;22(31):3607-30. Review.

PMID:
26219389
37.

6,7-Bismethoxy-2,11-dihydroxytetraphenylene Derived Macrocycles: Synthesis, Structures, and Complexation with Fullerenes.

Deng CL, Xiong XD, Chik DT, Cai Z, Peng XS, Wong HN.

Chem Asian J. 2015 Nov;10(11):2342-6. doi: 10.1002/asia.201500689. Epub 2015 Aug 11.

PMID:
26211744
38.

Structure and spectroscopic characterization of tetrathia- and tetraselena[8]circulenes as a new class of polyaromatic heterocycles.

Minaeva VA, Baryshnikov GV, Minaev BF, Karaush NN, Xiong XD, Li MD, Phillips DL, Wong HN.

Spectrochim Acta A Mol Biomol Spectrosc. 2015 Dec 5;151:247-61. doi: 10.1016/j.saa.2015.06.020. Epub 2015 Jun 25.

PMID:
26142658
39.

Synthesis and Application of [3.3.0]Furofuranone in Total Synthesis.

Peng XS, Ylagan RM, Siu YM, Wong HN.

Chem Asian J. 2015 Oct;10(10):2070-83. doi: 10.1002/asia.201500288. Epub 2015 Jul 20. Review.

PMID:
26083458
40.

A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease.

Spinale JM, Mariani LH, Kapoor S, Zhang J, Weyant R, Song PX, Wong HN, Troost JP, Gadegbeku CA, Gipson DS, Kretzler M, Nihalani D, Holzman LB; Nephrotic Syndrome Study Network.

Kidney Int. 2015 Mar;87(3):564-74. doi: 10.1038/ki.2014.346. Epub 2014 Oct 29.

41.

Tetrathio and tetraseleno[8]circulenes: synthesis, structures, and properties.

Xiong X, Deng CL, Minaev BF, Baryshnikov GV, Peng XS, Wong HN.

Chem Asian J. 2015 Apr;10(4):969-75. doi: 10.1002/asia.201403028. Epub 2014 Oct 16.

PMID:
25319048
42.

Our expedition in eight-membered ring compounds: from planar dehydrocyclooctenes to tub-shaped chiral tetraphenylenes.

Han JW, Li X, Wong HN.

Chem Rec. 2015 Feb;15(1):107-31. doi: 10.1002/tcr.201402047. Epub 2014 Oct 15.

PMID:
25316029
43.

Antiviral activity of Chinese medicine-derived phytochemicals against avian influenza A (H5N1) virus.

Ooi VE, Chiu LC, Sun SS, Chan PK, Wong HN.

Hong Kong Med J. 2014 Aug;20 Suppl 4:37-41. No abstract available.

44.

Heteroatom-bridged tetraphenylenes: synthesis, structures, and properties.

Xiong XD, Deng CL, Peng XS, Miao Q, Wong HN.

Org Lett. 2014 Jun 20;16(12):3252-5. doi: 10.1021/ol501267z. Epub 2014 Jun 9.

PMID:
24909846
45.

Asymmetric synthesis of 3,3,5,5-tetrasubstituted 1,2-dioxolanes: total synthesis of epiplakinic acid F.

Tian XY, Han JW, Zhao Q, Wong HN.

Org Biomol Chem. 2014 Jun 14;12(22):3686-700. doi: 10.1039/c4ob00448e. Epub 2014 Apr 28. Erratum in: Org Biomol Chem. 2014 Sep 7;12(33):6532.

PMID:
24769843
46.

Slit diaphragm protein Neph1 and its signaling: a novel therapeutic target for protection of podocytes against glomerular injury.

Arif E, Rathore YS, Kumari B, Ashish F, Wong HN, Holzman LB, Nihalani D.

J Biol Chem. 2014 Apr 4;289(14):9502-18. doi: 10.1074/jbc.M113.505743. Epub 2014 Feb 19.

47.

Enantiomeric recognition of amino acid salts by macrocyclic crown ethers derived from enantiomerically pure 1,8,9,16-tetrahydroxytetraphenylenes.

Cheng C, Cai Z, Peng XS, Wong HN.

J Org Chem. 2013 Sep 6;78(17):8562-73. doi: 10.1021/jo401240k. Epub 2013 Aug 22.

PMID:
23927033
48.

Interactions between artemisinins and other antimalarial drugs in relation to the cofactor model--a unifying proposal for drug action.

Haynes RK, Cheu KW, Chan HW, Wong HN, Li KY, Tang MM, Chen MJ, Guo ZF, Guo ZH, Sinniah K, Witte AB, Coghi P, Monti D.

ChemMedChem. 2012 Dec;7(12):2204-26. doi: 10.1002/cmdc.201200383. Epub 2012 Oct 30.

PMID:
23112085
49.

Novel BRCA1 and BRCA2 genomic rearrangements in Southern Chinese breast/ovarian cancer patients.

Kwong A, Ng EK, Law FB, Wong HN, Wa A, Wong CL, Kurian AW, West DW, Ford JM, Ma ES.

Breast Cancer Res Treat. 2012 Dec;136(3):931-3. doi: 10.1007/s10549-012-2292-1. Epub 2012 Oct 26. No abstract available.

50.

Identification of BRCA1/2 founder mutations in Southern Chinese breast cancer patients using gene sequencing and high resolution DNA melting analysis.

Kwong A, Ng EK, Wong CL, Law FB, Au T, Wong HN, Kurian AW, West DW, Ford JM, Ma ES.

PLoS One. 2012;7(9):e43994. doi: 10.1371/journal.pone.0043994. Epub 2012 Sep 7.

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