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Large-Scale Whole-Genome Sequencing Reveals the Genetic Architecture of Primary Membranoproliferative GN and C3 Glomerulopathy.

Levine AP, Chan MMY, Sadeghi-Alavijeh O, Wong EKS, Cook HT, Ashford S, Carss K, Christian MT, Hall M, Harris CL, McAlinden P, Marchbank KJ, Marks SD, Maxwell H, Megy K, Penkett CJ, Mozere M, Stirrups KE, Tuna S, Wessels J, Whitehorn D; MPGN/DDD/C3 Glomerulopathy Rare Disease Group; NIHR BioResource, Johnson SA, Gale DP.

J Am Soc Nephrol. 2020 Jan 9. pii: ASN.2019040433. doi: 10.1681/ASN.2019040433. [Epub ahead of print]


The comparative efficacy of disinfectant wipes on common-use computer keyboards in a veterinary teaching hospital.

Wong EK, Burgess BA, Brainard BM, Greene CE, Hurley DJ, Koenig A.

Can Vet J. 2020 Jan;61(1):69-74.


Selective reporting bias in randomised controlled trials from two network meta-analyses: comparison of clinical trial registrations and their respective publications.

Wong EK, Lachance CC, Page MJ, Watt J, Veroniki A, Straus SE, Tricco AC.

BMJ Open. 2019 Sep 5;9(9):e031138. doi: 10.1136/bmjopen-2019-031138.


Vision-based lane departure warning framework.

Em PP, Hossen J, Fitrian I, Wong EK.

Heliyon. 2019 Aug 6;5(8):e02169. doi: 10.1016/j.heliyon.2019.e02169. eCollection 2019 Aug.


Molecular Mechanism of Aggregation of the Cataract-Related γD-Crystallin W42R Variant from Multiscale Atomistic Simulations.

Wong EK, Prytkova V, Freites JA, Butts CT, Tobias DJ.

Biochemistry. 2019 Sep 3;58(35):3691-3699. doi: 10.1021/acs.biochem.9b00208. Epub 2019 Aug 19.


Consultation-Liaison Psychiatry in Hong Kong: a 2019 Update.

Mak ADP, Wong EKY.

East Asian Arch Psychiatry. 2019 Jun;29(2):39-40. No abstract available.


The Predictive Value of the Clinical Frailty Scale on Discharge Destination and Complications in Older Hip Fracture Patients.

Chan S, Wong EKC, Ward SE, Kuan D, Wong CL.

J Orthop Trauma. 2019 Oct;33(10):497-502. doi: 10.1097/BOT.0000000000001518.


Perceptions of genetic variant reclassification in patients with inherited cardiac disease.

Wong EK, Bartels K, Hathaway J, Burns C, Yeates L, Semsarian C, Krahn AD, Virani A, Ingles J.

Eur J Hum Genet. 2019 Jul;27(7):1134-1142. doi: 10.1038/s41431-019-0377-6. Epub 2019 Mar 21.


Role of Conformational Flexibility in Monte Carlo Simulations of Many-Protein Systems.

Majumdar BB, Prytkova V, Wong EK, Freites JA, Tobias DJ, Heyden M.

J Chem Theory Comput. 2019 Feb 12;15(2):1399-1408. doi: 10.1021/acs.jctc.8b00894. Epub 2019 Jan 28.


Role of venous blood gases in hypercapnic respiratory failure chronic obstructive pulmonary disease patients presenting to the emergency department.

Wong EKC, Lee PCS, Ansary S, Asha S, Wong KKH, Yee BJ, Ng AT.

Intern Med J. 2019 Jul;49(7):834-837. doi: 10.1111/imj.14186.


Thiamine versus placebo in older heart failure patients: study protocol for a randomized controlled crossover feasibility trial (THIAMINE-HF).

Wong EKC, Lee JY, Leong DP, Mbuagbaw L, Yousuf H, Keen S, Straus SE, Patterson CJ, Demers C.

Pilot Feasibility Stud. 2018 Sep 20;4:149. doi: 10.1186/s40814-018-0342-0. eCollection 2018.


Development and validation of a prognostic model for overall survival in chemotherapy-naïve men with metastatic castration-resistant prostate cancer.

Armstrong AJ, Lin P, Higano CS, Sternberg CN, Sonpavde G, Tombal B, Templeton AJ, Fizazi K, Phung D, Wong EK, Krivoshik A, Beer TM.

Ann Oncol. 2018 Nov 1;29(11):2200-2207. doi: 10.1093/annonc/mdy406.


Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma.

Song TL, Nairismägi ML, Laurensia Y, Lim JQ, Tan J, Li ZM, Pang WL, Kizhakeyil A, Wijaya GC, Huang DC, Nagarajan S, Chia BK, Cheah D, Liu YH, Zhang F, Rao HL, Tang T, Wong EK, Bei JX, Iqbal J, Grigoropoulos NF, Ng SB, Chng WJ, Teh BT, Tan SY, Verma NK, Fan H, Lim ST, Ong CK.

Blood. 2018 Sep 13;132(11):1146-1158. doi: 10.1182/blood-2018-01-829424. Epub 2018 Jul 27.


Nursing perspectives on the confusion assessment method: a qualitative focus group study.

Wong EK, Lee JY, Surendran AS, Nair K, Della Maestra N, Migliarini M, St Onge JA, Patterson CJ.

Age Ageing. 2018 Nov 1;47(6):880-886. doi: 10.1093/ageing/afy107.


Diseases of complement dysregulation-an overview.

Wong EKS, Kavanagh D.

Semin Immunopathol. 2018 Jan;40(1):49-64. doi: 10.1007/s00281-017-0663-8. Epub 2018 Jan 11. Review.


Long-Term Prognostic Implications of Cerebral Microbleeds in Chinese Patients With Ischemic Stroke.

Lau KK, Wong YK, Teo KC, Chang RSK, Tse MY, Hoi CP, Chan CY, Chan OL, Cheung RHK, Wong EKM, Kwan JSK, Hui ES, Mak HKF.

J Am Heart Assoc. 2017 Dec 7;6(12). pii: e007360. doi: 10.1161/JAHA.117.007360.


Factor H autoantibody is associated with atypical hemolytic uremic syndrome in children in the United Kingdom and Ireland.

Brocklebank V, Johnson S, Sheerin TP, Marks SD, Gilbert RD, Tyerman K, Kinoshita M, Awan A, Kaur A, Webb N, Hegde S, Finlay E, Fitzpatrick M, Walsh PR, Wong EKS, Booth C, Kerecuk L, Salama AD, Almond M, Inward C, Goodship TH, Sheerin NS, Marchbank KJ, Kavanagh D.

Kidney Int. 2017 Nov;92(5):1261-1271. doi: 10.1016/j.kint.2017.04.028. Epub 2017 Jul 24.


Hemolytic Uremic Syndrome in Pregnancy and Postpartum.

Bruel A, Kavanagh D, Noris M, Delmas Y, Wong EKS, Bresin E, Provôt F, Brocklebank V, Mele C, Remuzzi G, Loirat C, Frémeaux-Bacchi V, Fakhouri F.

Clin J Am Soc Nephrol. 2017 Aug 7;12(8):1237-1247. doi: 10.2215/CJN.00280117. Epub 2017 Jun 8.


Thrombotic Microangiopathy in Inverted Formin 2-Mediated Renal Disease.

Challis RC, Ring T, Xu Y, Wong EK, Flossmann O, Roberts IS, Ahmed S, Wetherall M, Salkus G, Brocklebank V, Fester J, Strain L, Wilson V, Wood KM, Marchbank KJ, Santibanez-Koref M, Goodship TH, Kavanagh D.

J Am Soc Nephrol. 2017 Apr;28(4):1084-1091. doi: 10.1681/ASN.2015101189. Epub 2016 Dec 14.


Spontaneous Regression of a Congenital Melanocytic Nevus by Sclerosis.

Wong EK, Mahmood MN, Salopek TG.

Pediatr Dermatol. 2016 Nov;33(6):e368-e371. doi: 10.1111/pde.12953. Epub 2016 Aug 30.


Treatment registry for outcomes in patients with castration-resistant prostate cancer (TRUMPET): a methodology for real-world evidence and research.

Penson DF, Lin DW, Karsh L, Quinn DI, Shevrin DH, Shore N, Symanowski JT, Brown B, Forer D, Wong EK, Flanders SC.

Future Oncol. 2016 Dec;12(23):2689-2699. Epub 2016 Aug 16.


DeepShape: Deep-Learned Shape Descriptor for 3D Shape Retrieval.

Jin Xie, Guoxian Dai, Fan Zhu, Wong EK, Yi Fang.

IEEE Trans Pattern Anal Mach Intell. 2017 Jul;39(7):1335-1345. doi: 10.1109/TPAMI.2016.2596722. Epub 2016 Jul 29.


Brain early infarct detection using gamma correction extreme-level eliminating with weighting distribution.

Teh V, Sim KS, Wong EK.

Scanning. 2016 Nov;38(6):842-856. doi: 10.1002/sca.21334. Epub 2016 Jun 15.


The role of ADAMTS-13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies.

Phillips EH, Westwood JP, Brocklebank V, Wong EK, Tellez JO, Marchbank KJ, McGuckin S, Gale DP, Connolly J, Goodship TH, Kavanagh D, Scully MA.

J Thromb Haemost. 2016 Jan;14(1):175-85. doi: 10.1111/jth.13189. Epub 2016 Jan 11.


A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome.

Challis RC, Araujo GS, Wong EK, Anderson HE, Awan A, Dorman AM, Waldron M, Wilson V, Brocklebank V, Strain L, Morgan BP, Harris CL, Marchbank KJ, Goodship TH, Kavanagh D.

J Am Soc Nephrol. 2016 Jun;27(6):1617-24. doi: 10.1681/ASN.2015010100. Epub 2015 Oct 21.


Increased hydrophobic surface exposure in the cataract-related G18V variant of human γS-crystallin.

Khago D, Wong EK, Kingsley CN, Freites JA, Tobias DJ, Martin RW.

Biochim Biophys Acta. 2016 Jan;1860(1 Pt B):325-32. doi: 10.1016/j.bbagen.2015.09.022. Epub 2015 Oct 14.


Thermal cycling can extend tool life in orthopaedic operating rooms.

Katchky RN, McLachlin SD, Wong EK, Finkelstein J, Kreder HJ, Whyne CM.

J Orthop Res. 2016 Mar;34(3):539-43. doi: 10.1002/jor.23035. Epub 2015 Sep 8.


An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy.

Nichols EM, Barbour TD, Pappworth IY, Wong EK, Palmer JM, Sheerin NS, Pickering MC, Marchbank KJ.

Kidney Int. 2015 Dec;88(6):1314-1322. doi: 10.1038/ki.2015.233. Epub 2015 Jul 29.


Sarcoidosis presenting with hypercalcaemia following withdrawal of long-term immunosuppression in renal transplantation.

Wong EK, Husain A, Sayer JA.

Oxf Med Case Reports. 2014 Aug 1;2014(5):86-8. doi: 10.1093/omcr/omu033. eCollection 2014 Aug.


A Biomechanical Assessment of Kyphoplasty as a Stand-Alone Treatment in a Human Cadaveric Burst Fracture Model.

Wong EK, Whyne CM, Singh D, Ford M.

Spine (Phila Pa 1976). 2015 Jul 15;40(14):E808-13. doi: 10.1097/BRS.0000000000000967.


Anticomplement C5 therapy with eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.

Wong EK, Kavanagh D.

Transl Res. 2015 Feb;165(2):306-20. doi: 10.1016/j.trsl.2014.10.010. Epub 2014 Oct 20. Review.


Atypical haemolytic uraemic syndrome associated with a CD46 mutation triggered by Shigella flexneri.

Brocklebank V, Wong EK, Fielding R, Goodship TH, Kavanagh D.

Clin Kidney J. 2014 Jun;7(3):286-288. Epub 2014 Apr 11.


Whole-exome sequencing identifies rare, functional CFH variants in families with macular degeneration.

Yu Y, Triebwasser MP, Wong EK, Schramm EC, Thomas B, Reynolds R, Mardis ER, Atkinson JP, Daly M, Raychaudhuri S, Kavanagh D, Seddon JM.

Hum Mol Genet. 2014 Oct 1;23(19):5283-93. doi: 10.1093/hmg/ddu226. Epub 2014 May 20.


Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN.

Wong EK, Anderson HE, Herbert AP, Challis RC, Brown P, Reis GS, Tellez JO, Strain L, Fluck N, Humphrey A, Macleod A, Richards A, Ahlert D, Santibanez-Koref M, Barlow PN, Marchbank KJ, Harris CL, Goodship TH, Kavanagh D.

J Am Soc Nephrol. 2014 Nov;25(11):2425-33. doi: 10.1681/ASN.2013070732. Epub 2014 Apr 10.


Procalcitonin, a valuable biomarker assisting clinical decision-making in the management of community-acquired pneumonia.

Lindstrom ST, Wong EK.

Intern Med J. 2014 Apr;44(4):390-7. doi: 10.1111/imj.12374.


Trace detection of perchlorate in industrial-grade emulsion explosive with portable surface-enhanced Raman spectroscopy.

Nuntawong N, Eiamchai P, Limwichean S, Wong-ek B, Horprathum M, Patthanasettakul V, Leelapojanaporn A, Nakngoenthong S, Chindaudom P.

Forensic Sci Int. 2013 Dec 10;233(1-3):174-8. doi: 10.1016/j.forsciint.2013.09.012. Epub 2013 Sep 17.


Peripheral neuropathy for dermatologists: what if not diabetic neuropathy?

Kwok T, Ting PT, Wong EK, Brassard A.

J Cutan Med Surg. 2013 Oct;17 Suppl 1:S1-5. Review.


Making sense of the spectrum of glomerular disease associated with complement dysregulation.

Johnson SA, Wong EK, Taylor CM.

Pediatr Nephrol. 2014 Oct;29(10):1883-94. doi: 10.1007/s00467-013-2559-8. Epub 2013 Jul 14. Review.


Randomized phase III trial of maintenance bevacizumab with or without pemetrexed after first-line induction with bevacizumab, cisplatin, and pemetrexed in advanced nonsquamous non-small-cell lung cancer: AVAPERL (MO22089).

Barlesi F, Scherpereel A, Rittmeyer A, Pazzola A, Ferrer Tur N, Kim JH, Ahn MJ, Aerts JG, Gorbunova V, Vikström A, Wong EK, Perez-Moreno P, Mitchell L, Groen HJ.

J Clin Oncol. 2013 Aug 20;31(24):3004-11. doi: 10.1200/JCO.2012.42.3749. Epub 2013 Jul 8.


Complement therapy in atypical haemolytic uraemic syndrome (aHUS).

Wong EK, Goodship TH, Kavanagh D.

Mol Immunol. 2013 Dec 15;56(3):199-212. doi: 10.1016/j.molimm.2013.05.224. Epub 2013 Jun 28. Review.


Borderline personality disorder in the east.

Wong EK.

Asian J Psychiatr. 2013 Feb;6(1):80-1. doi: 10.1016/j.ajp.2012.05.004. Epub 2012 Jul 11. Review. No abstract available.


Automated beam placement for breast radiotherapy using a support vector machine based algorithm.

Zhao X, Kong D, Jozsef G, Chang J, Wong EK, Formenti SC, Wang Y.

Med Phys. 2012 May;39(5):2536-43. doi: 10.1118/1.3700736.


Severe intestinal oedema due to nephrotic syndrome.

Wong EK, Brady M, Sheerin NS.

QJM. 2013 Feb;106(2):191-2. doi: 10.1093/qjmed/hcr236. Epub 2012 Feb 1. No abstract available.


Surface-enhanced Raman scattering using silver nanocluster on anodic aluminum oxide template sensor toward protein detection.

Wong-Ek K, Chailapakul O, Eiamchai P, Horpratum M, Limnonthakul P, Patthanasettakul V, Sutapan B, Tuantranont A, Chindaudom P, Nuntawong N.

Biomed Tech (Berl). 2011 Aug;56(4):235-40. doi: 10.1515/BMT.2011.103.


A support vector machine (SVM) for predicting preferred treatment position in radiotherapy of patients with breast cancer.

Zhao X, Wong EK, Wang Y, Lymberis S, Wen B, Formenti S, Chang J.

Med Phys. 2010 Oct;37(10):5341-50.


Cardiac troponin T detection using polymers coated quartz crystal microbalance as a cost-effective immunosensor.

Wong-ek K, Chailapakul O, Nuntawong N, Jaruwongrungsee K, Tuantranont A.

Biomed Tech (Berl). 2010 Oct;55(5):279-84. doi: 10.1515/BMT.2010.036. Epub 2010 Sep 15.


Strength profiles of shoulder rotators in healthy sport climbers and nonclimbers.

Wong EK, Ng GY.

J Athl Train. 2009 Sep-Oct;44(5):527-30. doi: 10.4085/1062-6050-44.5.527.


Follicular lymphoma in the United States: first report of the national LymphoCare study.

Friedberg JW, Taylor MD, Cerhan JR, Flowers CR, Dillon H, Farber CM, Rogers ES, Hainsworth JD, Wong EK, Vose JM, Zelenetz AD, Link BK.

J Clin Oncol. 2009 Mar 10;27(8):1202-8. doi: 10.1200/JCO.2008.18.1495. Epub 2009 Feb 9.

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