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Associations Between Left Ventricular Structure, Function, and Cerebral Amyloid: The ARIC-PET Study.

Johansen MC, Mosley TH, Knopman DS, Wong DF, Wagenknecht LE, Shah AM, Solomon SD, Gottesman RF.

Stroke. 2019 Oct 10:STROKEAHA119027220. doi: 10.1161/STROKEAHA.119.027220. [Epub ahead of print]


Tau pathology in cognitively normal older adults.

Ziontz J, Bilgel M, Shafer AT, Moghekar A, Elkins W, Helphrey J, Gomez G, June D, McDonald MA, Dannals RF, Azad BB, Ferrucci L, Wong DF, Resnick SM.

Alzheimers Dement (Amst). 2019 Sep 6;11:637-645. doi: 10.1016/j.dadm.2019.07.007. eCollection 2019 Dec.


Transcranial Recording of Electrophysiological Neural Activity in the Rodent Brain in vivo Using Functional Photoacoustic Imaging of Near-Infrared Voltage-Sensitive Dye.

Kang J, Zhang HK, Kadam SD, Fedorko J, Valentine H, Malla AP, Yan P, Harraz MM, Kang JU, Rahmim A, Gjedde A, Loew LM, Wong DF, Boctor EM.

Front Neurosci. 2019 Aug 9;13:579. doi: 10.3389/fnins.2019.00579. eCollection 2019.


High availability of the α7 nicotinic acetylcholine receptor in brains of individuals with mild cognitive impairment: A pilot study using 18F-ASEM PET.

Coughlin JM, Rubin LH, Du Y, Rowe SP, Crawford JL, Rosenthal HB, Frey SM, Marshall ES, Shinehouse LK, Chen A, Speck CL, Wang Y, Lesniak WG, Minn I, Bakker A, Kamath V, Smith GS, Albert MS, Behnam Azad B, Dannals RF, Horti AG, Wong DF, Pomper MG.

J Nucl Med. 2019 Aug 16. pii: jnumed.119.230979. doi: 10.2967/jnumed.119.230979. [Epub ahead of print]


Cognitive-behavior therapy with and without parental involvement for anxious Chinese adolescents: A randomized controlled trial.

Wong DFK, Ng TK, Zhuang XY, Wong PWC, Leung JTY, Cheung IKM, Kendall PC.

J Fam Psychol. 2019 Aug 15. doi: 10.1037/fam0000585. [Epub ahead of print]


Comparing dyadic cognitive behavioral therapy (CBT) with dyadic integrative body-mind-spirit intervention (I-BMS) for Chinese family caregivers of lung cancer patients: a randomized controlled trial.

Xiu D, Fung YL, Lau BH, Wong DFK, Chan CHY, Ho RTH, So TH, Lam TC, Lee VH, Lee AWM, Chow SF, Lim FM, Tsang MW, Chan CLW, Chow AYM.

Support Care Cancer. 2019 Jul 6. doi: 10.1007/s00520-019-04974-z. [Epub ahead of print]


Peer-Reviewed Validation of a Comprehensive Framework for Disaster Evaluation Typologies.

Wong DF, Spencer C, Boyd L, Burkle FM, Archer F.

Prehosp Disaster Med. 2019 Jun;34(3):230-240. doi: 10.1017/S1049023X19004400.


Effect of STN DBS on vesicular monoamine transporter 2 and glucose metabolism in Parkinson's disease.

Smith GS, Mills KA, Pontone GM, Anderson WS, Perepezko KM, Brasic J, Zhou Y, Brandt J, Butson CR, Holt DP, Mathews WB, Dannals RF, Wong DF, Mari Z.

Parkinsonism Relat Disord. 2019 Jul;64:235-241. doi: 10.1016/j.parkreldis.2019.04.006. Epub 2019 Apr 16.


The effect of ApoE ε4 on longitudinal brain region-specific glucose metabolism in patients with mild cognitive impairment: a FDG-PET study.

Paranjpe MD, Chen X, Liu M, Paranjpe I, Leal JP, Wang R, Pomper MG, Wong DF, Benzinger TLS, Zhou Y; Alzheimer's Disease Neuroimaging Initiative.

Neuroimage Clin. 2019;22:101795. doi: 10.1016/j.nicl.2019.101795. Epub 2019 Mar 28.


Association of Head Injury with Brain Amyloid Deposition: The ARIC-PET Study.

Schneider ALC, Selvin E, Liang M, Latour L, Turtzo LC, Koton S, Coresh J, Mosley T, Whitlow CT, Zhou Y, Wong DF, Ling G, Gottesman RF.

J Neurotrauma. 2019 Sep 1;36(17):2549-2557. doi: 10.1089/neu.2018.6213. Epub 2019 May 23.


Sex differences in the association between amyloid and longitudinal brain volume change in cognitively normal older adults.

Armstrong NM, Huang CW, Williams OA, Bilgel M, An Y, Doshi J, Erus G, Davatzikos C, Wong DF, Ferrucci L, Resnick SM.

Neuroimage Clin. 2019;22:101769. doi: 10.1016/j.nicl.2019.101769. Epub 2019 Mar 11.


Association of PET-measured myocardial flow reserve with echocardiography-estimated pulmonary artery systolic pressure in patients with hypertrophic cardiomyopathy.

Zhao M, Liu M, Leal JP, Tsui BMW, Wong DF, Pomper MG, Zhou Y.

PLoS One. 2019 Mar 20;14(3):e0212573. doi: 10.1371/journal.pone.0212573. eCollection 2019.


Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life.

Rawlings AM, Sharrett AR, Mosley TH, Wong DF, Knopman DS, Gottesman RF.

J Alzheimers Dis. 2019;68(2):517-521. doi: 10.3233/JAD-180785.


Longitudinal evaluation of surrogates of regional cerebral blood flow computed from dynamic amyloid PET imaging.

Bilgel M, Beason-Held L, An Y, Zhou Y, Wong DF, Resnick SM.

J Cereb Blood Flow Metab. 2019 Feb 12:271678X19830537. doi: 10.1177/0271678X19830537. [Epub ahead of print]


PET imaging of dopamine release in the frontal cortex of manganese-exposed non-human primates.

Guilarte TR, Yeh CL, McGlothan JL, Perez J, Finley P, Zhou Y, Wong DF, Dydak U, Schneider JS.

J Neurochem. 2019 Jul;150(2):188-201. doi: 10.1111/jnc.14681. Epub 2019 Mar 26.


Vestibular Function and Beta-Amyloid Deposition in the Baltimore Longitudinal Study of Aging.

Kamil RJ, Bilgel M, Wong DF, Resnick SM, Agrawal Y.

Front Aging Neurosci. 2018 Dec 11;10:408. doi: 10.3389/fnagi.2018.00408. eCollection 2018.


Dopamine D2 receptor occupancy of lumateperone (ITI-007): a Positron Emission Tomography Study in patients with schizophrenia.

Vanover KE, Davis RE, Zhou Y, Ye W, Brašić JR, Gapasin L, Saillard J, Weingart M, Litman RE, Mates S, Wong DF.

Neuropsychopharmacology. 2019 Feb;44(3):598-605. doi: 10.1038/s41386-018-0251-1. Epub 2018 Oct 26.


Prevalence of depressive symptoms among adolescents in secondary school in mainland China: A systematic review and meta-analysis.

Tang X, Tang S, Ren Z, Wong DFK.

J Affect Disord. 2019 Feb 15;245:498-507. doi: 10.1016/j.jad.2018.11.043. Epub 2018 Nov 5.


The Association of Mid- and Late-Life Systemic Inflammation with Brain Amyloid Deposition: The ARIC-PET Study.

Walker KA, Windham BG, Brown CH, Knopman DS, Jack CR, Mosley TH, Selvin E, Wong DF, Hughes TM, Zhou Y, Gross AL, Gottesman RF.

J Alzheimers Dis. 2018;66(3):1041-1052. doi: 10.3233/JAD-180469.


Voltage-sensitive dye delivery through the blood brain barrier using adenosine receptor agonist regadenoson.

Pak RW, Kang J, Valentine H, Loew LM, Thorek DLJ, Boctor EM, Wong DF, Kang JU.

Biomed Opt Express. 2018 Jul 30;9(8):3915-3922. doi: 10.1364/BOE.9.003915. eCollection 2018 Aug 1.


Early affective changes and increased connectivity in preclinical Alzheimer's disease.

Fredericks CA, Sturm VE, Brown JA, Hua AY, Bilgel M, Wong DF, Resnick SM, Seeley WW.

Alzheimers Dement (Amst). 2018 Jul 6;10:471-479. doi: 10.1016/j.dadm.2018.06.002. eCollection 2018.


Excessive daytime sleepiness and napping in cognitively normal adults: associations with subsequent amyloid deposition measured by PiB PET.

Spira AP, An Y, Wu MN, Owusu JT, Simonsick EM, Bilgel M, Ferrucci L, Wong DF, Resnick SM.

Sleep. 2018 Dec 1;41(12). doi: 10.1093/sleep/zsy184. No abstract available.


Excessive daytime sleepiness and napping in cognitively normal adults: associations with subsequent amyloid deposition measured by PiB PET.

Spira AP, An Y, Wu MN, Owusu JT, Simonsick EM, Bilgel M, Ferrucci L, Wong DF, Resnick SM.

Sleep. 2018 Oct 1;41(10). doi: 10.1093/sleep/zsy152. Erratum in: Sleep. 2018 Dec 1;41(12):.


Metabolic Syndrome and Amyloid Accumulation in the Aging Brain.

Gomez G, Beason-Held LL, Bilgel M, An Y, Wong DF, Studenski S, Ferrucci L, Resnick SM.

J Alzheimers Dis. 2018;65(2):629-639. doi: 10.3233/JAD-180297.


Evaluation of 18F-RO-948 PET for Quantitative Assessment of Tau Accumulation in the Human Brain.

Kuwabara H, Comley RA, Borroni E, Honer M, Kitmiller K, Roberts J, Gapasin L, Mathur A, Klein G, Wong DF.

J Nucl Med. 2018 Dec;59(12):1877-1884. doi: 10.2967/jnumed.118.214437. Epub 2018 Aug 10.


Remission of Gilles de la Tourette Syndrome after Heat-Induced Dehydration.

Robert Brašić J, Mari Z, Lerner A, Raymont V, Zaidi E, Wong DF.

Int J Phys Med Rehabil. 2018;6(3). pii: 472. doi: 10.4172/2329-9096.1000472. Epub 2018 Jun 13.


Standardization of amyloid quantitation with florbetapir standardized uptake value ratios to the Centiloid scale.

Navitsky M, Joshi AD, Kennedy I, Klunk WE, Rowe CC, Wong DF, Pontecorvo MJ, Mintun MA, Devous MD Sr.

Alzheimers Dement. 2018 Dec;14(12):1565-1571. doi: 10.1016/j.jalz.2018.06.1353. Epub 2018 Jul 11.


Image reconstruction in fluorescence molecular tomography with sparsity-initialized maximum-likelihood expectation maximization.

Zhu Y, Jha AK, Wong DF, Rahmim A.

Biomed Opt Express. 2018 Jun 13;9(7):3106-3121. doi: 10.1364/BOE.9.003106. eCollection 2018 Jul 1.


A cholecystokinin B receptor antagonist and cocaine interaction, phase I study.

Elkashef A, Brašić JR, Cantelina LR Jr, Kahn R, Chiang N, Ye W, Zhou Y, Mojsiak J, Warren KR, Crabb A, Hilton J, Wong DF, Vocci F.

CNS Neurosci Ther. 2019 Jan;25(1):136-146. doi: 10.1111/cns.12994. Epub 2018 Jun 20.


Effects of amyloid pathology and neurodegeneration on cognitive change in cognitively normal adults.

Bilgel M, An Y, Helphrey J, Elkins W, Gomez G, Wong DF, Davatzikos C, Ferrucci L, Resnick SM.

Brain. 2018 Aug 1;141(8):2475-2485. doi: 10.1093/brain/awy150.


Facing death alone or together? Investigating the interdependence of death anxiety, dysfunctional attitudes, and quality of life in patient-caregiver dyads confronting lung cancer.

Lau BH, Wong DFK, Fung YL, Zhou J, Chan CLW, Chow AYM.

Psychooncology. 2018 Aug;27(8):2045-2051. doi: 10.1002/pon.4773. Epub 2018 Jun 14.


Are dopamine receptor and transporter changes in Rett syndrome reflected in Mecp2-deficient mice?

Wong DF, Blue ME, Brašić JR, Nandi A, Valentine H, Stansfield KH, Rousset O, Bibat G, Yablonski ME, Johnston MV, Gjedde A, Naidu S.

Exp Neurol. 2018 Sep;307:74-81. doi: 10.1016/j.expneurol.2018.05.019. Epub 2018 May 18.


Caregiving burden and psychological distress in Chinese spousal caregivers: gender difference in the moderating role of positive aspects of caregiving.

Wong DFK, Ng TK, Zhuang XY.

Aging Ment Health. 2019 Aug;23(8):976-983. doi: 10.1080/13607863.2018.1474447. Epub 2018 May 21.


Characterization of 3 Novel Tau Radiopharmaceuticals, 11C-RO-963, 11C-RO-643, and 18F-RO-948, in Healthy Controls and in Alzheimer Subjects.

Wong DF, Comley RA, Kuwabara H, Rosenberg PB, Resnick SM, Ostrowitzki S, Vozzi C, Boess F, Oh E, Lyketsos CG, Honer M, Gobbi L, Klein G, George N, Gapasin L, Kitzmiller K, Roberts J, Sevigny J, Nandi A, Brasic J, Mishra C, Thambisetty M, Mogekar A, Mathur A, Albert M, Dannals RF, Borroni E.

J Nucl Med. 2018 Dec;59(12):1869-1876. doi: 10.2967/jnumed.118.209916. Epub 2018 May 4. Erratum in: J Nucl Med. 2019 Jan;60(1):141.


Incorporating reflection boundary conditions in the Neumann series radiative transport equation: application to photon propagation and reconstruction in diffuse optical imaging.

Jha AK, Zhu Y, Arridge S, Wong DF, Rahmim A.

Biomed Opt Express. 2018 Mar 1;9(4):1389-1407. doi: 10.1364/BOE.9.001389. eCollection 2018 Apr 1.


Brain PET Imaging of α7-nAChR with [18F]ASEM: Reproducibility, Occupancy, Receptor Density, and Changes in Schizophrenia.

Wong DF, Kuwabara H, Horti AG, Roberts JM, Nandi A, Cascella N, Brasic J, Weerts EM, Kitzmiller K, Phan JA, Gapasin L, Sawa A, Valentine H, Wand G, Mishra C, George N, McDonald M, Lesniak W, Holt DP, Azad BB, Dannals RF, Kem W, Freedman R, Gjedde A.

Int J Neuropsychopharmacol. 2018 Jul 1;21(7):656-667. doi: 10.1093/ijnp/pyy021.


Synthesis and Evaluation of a New 18F-Labeled Radiotracer for Studying the GABAB Receptor in the Mouse Brain.

Naik R, Valentine H, Dannals RF, Wong DF, Horti AG.

ACS Chem Neurosci. 2018 Jun 20;9(6):1453-1461. doi: 10.1021/acschemneuro.8b00038. Epub 2018 Mar 9.


18F-XTRA PET for Enhanced Imaging of the Extrathalamic α4β2 Nicotinic Acetylcholine Receptor.

Coughlin JM, Slania S, Du Y, Rosenthal HB, Lesniak WG, Minn I, Smith GS, Dannals RF, Kuwabara H, Wong DF, Wang Y, Horti AG, Pomper MG.

J Nucl Med. 2018 Oct;59(10):1603-1608. doi: 10.2967/jnumed.117.205492. Epub 2018 Mar 1.


The impact of perceived discrimination on personality among Chinese migrant children: The moderating role of parental support.

Xiang X, Wong DFK, Hou K.

Int J Soc Psychiatry. 2018 May;64(3):248-257. doi: 10.1177/0020764018758123. Epub 2018 Feb 22.


Metabotropic glutamate receptor 5 tracer [18F]-FPEB displays increased binding potential in postcentral gyrus and cerebellum of male individuals with autism: a pilot PET study.

Fatemi SH, Wong DF, Brašić JR, Kuwabara H, Mathur A, Folsom TD, Jacob S, Realmuto GM, Pardo JV, Lee S.

Cerebellum Ataxias. 2018 Feb 12;5:3. doi: 10.1186/s40673-018-0082-1. eCollection 2018.


β-amyloid deposition is associated with gait variability in usual aging.

Tian Q, Bair WN, Resnick SM, Bilgel M, Wong DF, Studenski SA.

Gait Posture. 2018 Mar;61:346-352. doi: 10.1016/j.gaitpost.2018.02.002. Epub 2018 Feb 6.


Feasibility Evaluation of Myocardial Cannabinoid Type 1 Receptor Imaging in Obesity: A Translational Approach.

Valenta I, Varga ZV, Valentine H, Cinar R, Horti A, Mathews WB, Dannals RF, Steele K, Kunos G, Wahl RL, Pomper MG, Wong DF, Pacher P, Schindler TH.

JACC Cardiovasc Imaging. 2018 Feb;11(2 Pt 2):320-332. doi: 10.1016/j.jcmg.2017.11.019.


Study protocol of a randomized controlled trial comparing integrative body-mind-spirit intervention and cognitive behavioral therapy in fostering quality of life of patients with lung cancer and their family caregivers.

Lau BH, Chow AYM, Wong DFK, Chan JSM, Chan CHY, Ho RTH, So TH, Lam TC, Lee VH, Lee AWM, Chow SF, Chan CLW.

J Evid Inf Soc Work. 2018 May-Jun;15(3):258-276. doi: 10.1080/23761407.2018.1435325. Epub 2018 Feb 5.


Evaluating the Effectiveness of an Integrated Cognitive-Behavioural Intervention (CBI) Model for Male Problem Gamblers in Hong Kong: A Matched-Pair Comparison Design.

Zhuang XY, Wong DFK, Ng TK, Jackson AC, Dowling NA, Lo HH.

J Gambl Stud. 2018 Sep;34(3):969-985. doi: 10.1007/s10899-018-9747-1.


Radioligand binding analysis of α 2 adrenoceptors with [11C]yohimbine in brain in vivo: Extended Inhibition Plot correction for plasma protein binding.

Phan JA, Landau AM, Jakobsen S, Wong DF, Gjedde A.

Sci Rep. 2017 Nov 22;7(1):15979. doi: 10.1038/s41598-017-16020-1. Erratum in: Sci Rep. 2018 Apr 16;8(1):6249.


The efficacy of cognitive behavioral therapy for Chinese people: A meta-analysis.

Ng TK, Wong DFK.

Aust N Z J Psychiatry. 2018 Jul;52(7):620-637. doi: 10.1177/0004867417741555. Epub 2017 Nov 16.


The distribution of the alpha7 nicotinic acetylcholine receptor in healthy aging: An in vivo positron emission tomography study with [18F]ASEM.

Coughlin JM, Du Y, Rosenthal HB, Slania S, Min Koo S, Park A, Solomon G, Vranesic M, Antonsdottir I, Speck CL, Rootes-Murdy K, Lerner A, Rowe SP, Wang Y, Lesniak WG, Minn I, Bakker A, Smith GS, Dannals RF, Kuwabara H, Horti A, Wong DF, Pomper MG.

Neuroimage. 2018 Jan 15;165:118-124. doi: 10.1016/j.neuroimage.2017.10.009. Epub 2017 Oct 7.


Preclinical Evaluation of 18F-RO6958948, 11C-RO6931643, and 11C-RO6924963 as Novel PET Radiotracers for Imaging Tau Aggregates in Alzheimer Disease.

Honer M, Gobbi L, Knust H, Kuwabara H, Muri D, Koerner M, Valentine H, Dannals RF, Wong DF, Borroni E.

J Nucl Med. 2018 Apr;59(4):675-681. doi: 10.2967/jnumed.117.196741. Epub 2017 Sep 28.


Negative Mood States or Dysfunctional Cognitions: Their Independent and Interactional Effects in Influencing Severity of Gambling Among Chinese Problem Gamblers in Hong Kong.

Wong DFK, Zhuang XY, Jackson A, Dowling N, Lo HHM.

J Gambl Stud. 2018 Sep;34(3):631-645. doi: 10.1007/s10899-017-9714-2.


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