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Items: 1 to 50 of 475

1.

Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC.

Wei L, Lee D, Law CT, Zhang MS, Shen J, Chin DW, Zhang A, Tsang FH, Wong CL, Ng IO, Wong CC, Wong CM.

Nat Commun. 2019 Oct 15;10(1):4681. doi: 10.1038/s41467-019-12606-7.

2.

Adenoviral Infections in Singapore: Should New Antiviral Therapies and Vaccines Be Adopted?

Coleman KK, Wong CC, Jayakumar J, Nguyen TT, Wong AWL, Yadana S, Thoon KC, Chan KP, Low JG, Kalimuddin S, Dehghan S, Kang J, Shamsaddini A, Seto D, Su YCF, Gray GC.

J Infect Dis. 2019 Sep 30. pii: jiz489. doi: 10.1093/infdis/jiz489. [Epub ahead of print]

PMID:
31563943
3.

Prostaglandin E2 induces DNA hypermethylation in gastric cancer in vitro and in vivo.

Wong CC, Kang W, Xu J, Qian Y, Luk STY, Chen H, Li W, Zhao L, Zhang X, Chiu PW, Ng EK, Yu J.

Theranostics. 2019 Aug 14;9(21):6256-6268. doi: 10.7150/thno.35766. eCollection 2019.

4.

Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity.

Long X, Wong CC, Tong L, Chu ESH, Ho Szeto C, Go MYY, Coker OO, Chan AWH, Chan FKL, Sung JJY, Yu J.

Nat Microbiol. 2019 Sep 9. doi: 10.1038/s41564-019-0541-3. [Epub ahead of print]

PMID:
31501538
5.

Histone chaperone FACT complex mediates oxidative stress response to promote liver cancer progression.

Shen J, Chen M, Lee D, Law CT, Wei L, Tsang FH, Chin DW, Cheng CL, Lee JM, Ng IO, Wong CC, Wong CM.

Gut. 2019 Aug 22. pii: gutjnl-2019-318668. doi: 10.1136/gutjnl-2019-318668. [Epub ahead of print]

PMID:
31439637
6.

APLN promotes hepatocellular carcinoma through activating PI3K/Akt pathway and is a druggable target.

Chen H, Wong CC, Liu D, Go MYY, Wu B, Peng S, Kuang M, Wong N, Yu J.

Theranostics. 2019 Jul 9;9(18):5246-5260. doi: 10.7150/thno.34713. eCollection 2019.

7.

Seroepidemiology and genotyping of hepatitis E virus in Singapore reveal rise in number of cases and similarity of human strains to those detected in pig livers.

Wong CC, Thean SM, Ng Y, Kang JSL, Ng TY, Chau ML, Koh TH, Chan KP.

Zoonoses Public Health. 2019 Nov;66(7):773-782. doi: 10.1111/zph.12624. Epub 2019 Jul 11.

PMID:
31293095
8.

TRIM67 Activates p53 to Suppress Colorectal Cancer Initiation and Progression.

Wang S, Zhang Y, Huang J, Wong CC, Zhai J, Li C, Wei G, Zhao L, Wang G, Wei H, Zhao Z, Yu J.

Cancer Res. 2019 Aug 15;79(16):4086-4098. doi: 10.1158/0008-5472.CAN-18-3614. Epub 2019 Jun 25.

PMID:
31239268
9.

Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue.

Wong CCY, Smith RG, Hannon E, Ramaswami G, Parikshak NN, Assary E, Troakes C, Poschmann J, Schalkwyk LC, Sun W, Prabhakar S, Geschwind DH, Mill J.

Hum Mol Genet. 2019 Jul 1;28(13):2201-2211. doi: 10.1093/hmg/ddz052.

10.

Hypoxia and the Metastatic Niche.

Chan CY, Yuen VW, Wong CC.

Adv Exp Med Biol. 2019;1136:97-112. doi: 10.1007/978-3-030-12734-3_7. Review.

PMID:
31201719
11.

Self-stigma predicts lower quality of life in Chinese American breast cancer survivors: exploring the mediating role of intrusive thoughts and posttraumatic growth.

Wong CCY, Pan-Weisz BM, Pan-Weisz TM, Yeung NCY, Mak WWS, Lu Q.

Qual Life Res. 2019 Oct;28(10):2753-2760. doi: 10.1007/s11136-019-02213-w. Epub 2019 May 23.

PMID:
31123880
12.

Biocompatibility and Osteogenic Capacity of Mg-Zn-Ca Bulk Metallic Glass for Rabbit Tendon-Bone Interference Fixation.

Wong CC, Wong PC, Tsai PH, Jang JS, Cheng CK, Chen HH, Chen CH.

Int J Mol Sci. 2019 May 3;20(9). pii: E2191. doi: 10.3390/ijms20092191.

13.

Prescription patterns of anti-diabetic medications and clinical outcomes in Asian patients with heart failure and diabetes mellitus.

Chia YMF, Teng TK, Tay WT, Anand I, MacDonald MR, Yap J, Chandramouli C, Richards AM, Tromp J, Ouwerkerk W, Ling LH, Lam CSP; ASIAN-HF Investigators.

Eur J Heart Fail. 2019 May;21(5):685-688. doi: 10.1002/ejhf.1467. Epub 2019 Apr 29. No abstract available.

PMID:
31033098
14.

A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development.

De Franco E, Watson RA, Weninger WJ, Wong CC, Flanagan SE, Caswell R, Green A, Tudor C, Lelliott CJ, Geyer SH, Maurer-Gesek B, Reissig LF, Lango Allen H, Caliebe A, Siebert R, Holterhus PM, Deeb A, Prin F, Hilbrands R, Heimberg H, Ellard S, Hattersley AT, Barroso I.

Am J Hum Genet. 2019 May 2;104(5):985-989. doi: 10.1016/j.ajhg.2019.03.018. Epub 2019 Apr 18.

15.

Post-implantation Deformation of Titanium Rod and Cobalt Chrome Rod in Adolescent Idiopathic Scoliosis.

Sia U, Tan BB, Teo YY, Wong CC.

Malays Orthop J. 2019 Mar;13(1):14-19. doi: 10.5704/MOJ.1903.002.

16.

YY1 regulates skeletal muscle regeneration through controlling metabolic reprogramming of satellite cells.

Chen F, Zhou J, Li Y, Zhao Y, Yuan J, Cao Y, Wang L, Zhang Z, Zhang B, Wang CC, Cheung TH, Wu Z, Wong CC, Sun H, Wang H.

EMBO J. 2019 May 15;38(10). pii: e99727. doi: 10.15252/embj.201899727. Epub 2019 Apr 12.

PMID:
30979776
17.

NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.

Wang J, Chen J, Wu G, Zhang H, Du X, Chen S, Zhang L, Wang K, Fan J, Gao S, Wu X, Zhang S, Kuai B, Zhao P, Chi B, Wang L, Li G, Wong CCL, Zhou Y, Li J, Yun C, Cheng H.

Genes Dev. 2019 May 1;33(9-10):536-549. doi: 10.1101/gad.322602.118. Epub 2019 Mar 6.

PMID:
30842217
18.

Respiratory health effects of household cleaning products on Hong Kong school children.

Lao XQ, Ho KF, Wong CC, Tian LW.

Hong Kong Med J. 2019 Feb;25 Suppl 3(1):24-26. No abstract available.

19.

Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.

Ding Z, Xu C, Sahu I, Wang Y, Fu Z, Huang M, Wong CCL, Glickman MH, Cong Y.

Mol Cell. 2019 Mar 21;73(6):1150-1161.e6. doi: 10.1016/j.molcel.2019.01.018. Epub 2019 Feb 18.

PMID:
30792173
20.

Establishing a generalized polyepigenetic biomarker for tobacco smoking.

Sugden K, Hannon EJ, Arseneault L, Belsky DW, Broadbent JM, Corcoran DL, Hancox RJ, Houts RM, Moffitt TE, Poulton R, Prinz JA, Thomson WM, Williams BS, Wong CCY, Mill J, Caspi A.

Transl Psychiatry. 2019 Feb 15;9(1):92. doi: 10.1038/s41398-019-0430-9.

21.

PKNOX2 suppresses gastric cancer through the transcriptional activation of IGFBP5 and p53.

Zhang L, Li W, Cao L, Xu J, Qian Y, Chen H, Zhang Y, Kang W, Gou H, Wong CC, Yu J.

Oncogene. 2019 Jun;38(23):4590-4604. doi: 10.1038/s41388-019-0743-4. Epub 2019 Feb 11.

22.

Assessment of Stabilization and Activity of the HIFs Important for Hypoxia-Induced Signalling in Cancer Cells.

Chiu DK, Zhang MS, Tse AP, Wong CC.

Methods Mol Biol. 2019;1928:77-99. doi: 10.1007/978-1-4939-9027-6_6.

PMID:
30725452
23.

Aberrant Super-Enhancer Landscape in Human Hepatocellular Carcinoma.

Tsang FH, Law CT, Tang TC, Cheng CL, Chin DW, Tam WV, Wei L, Wong CC, Ng IO, Wong CM.

Hepatology. 2019 Jun;69(6):2502-2517. doi: 10.1002/hep.30544. Epub 2019 Apr 16.

PMID:
30723918
24.

Longitudinal investigation of DNA methylation changes preceding adolescent psychotic experiences.

Roberts S, Suderman M, Zammit S, Watkins SH, Hannon E, Mill J, Relton C, Arseneault L, Wong CCY, Fisher HL.

Transl Psychiatry. 2019 Feb 4;9(1):69. doi: 10.1038/s41398-019-0407-8.

25.

Estimating blood pressure trends and the nocturnal dip from photoplethysmography.

Radha M, de Groot K, Rajani N, Wong CCP, Kobold N, Vos V, Fonseca P, Mastellos N, Wark PA, Velthoven N, Haakma R, Aarts RM.

Physiol Meas. 2019 Feb 26;40(2):025006. doi: 10.1088/1361-6579/ab030e.

PMID:
30699397
26.

Mobile self-compassion programme for promotion of public mental health: a randomised controlled trial.

Mak WW, Wong CC, Chan AT, Lau JT.

Hong Kong Med J. 2019 Feb;25 Suppl 2(1):15-17. No abstract available.

27.

Acculturation Moderates the Effects of Expressive Writing on Post-Traumatic Stress Symptoms Among Chinese American Breast Cancer Survivors.

Chu Q, Wong CCY, Lu Q.

Int J Behav Med. 2019 Apr;26(2):185-194. doi: 10.1007/s12529-019-09769-4.

PMID:
30656609
28.

The value of MR T2* measurements in normal and osteoarthritic knee cartilage: effects of age, sex, and location.

Tsai PH, Wong CC, Chan WP, Lu TW.

Eur Radiol. 2019 Aug;29(8):4514-4522. doi: 10.1007/s00330-018-5826-z. Epub 2019 Jan 7.

PMID:
30617477
29.

Ate1-mediated posttranslational arginylation affects substrate adhesion and cell migration in Dictyostelium discoideum.

Batsios P, Ishikawa-Ankerhold HC, Roth H, Schleicher M, Wong CCL, Müller-Taubenberger A.

Mol Biol Cell. 2019 Feb 15;30(4):453-466. doi: 10.1091/mbc.E18-02-0132. Epub 2018 Dec 26.

30.

Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma.

Wong K, Robles-Espinoza CD, Rodriguez D, Rudat SS, Puig S, Potrony M, Wong CC, Hewinson J, Aguilera P, Puig-Butille JA, Bressac-de Paillerets B, Zattara H, van der Weyden L, Fletcher CDM, Brenn T, Arends MJ, Quesada V, Newton-Bishop JA, Lopez-Otin C, Bishop DT, Harms PW, Johnson TM, Durham AB, Lombard DB, Adams DJ.

JAMA Dermatol. 2019 May 1;155(5):604-609. doi: 10.1001/jamadermatol.2018.3662.

PMID:
30586141
31.

Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma.

Lee D, Xu IM, Chiu DK, Leibold J, Tse AP, Bao MH, Yuen VW, Chan CY, Lai RK, Chin DW, Chan DF, Cheung TT, Chok SH, Wong CM, Lowe SW, Ng IO, Wong CC.

Hepatology. 2019 Apr;69(4):1768-1786. doi: 10.1002/hep.30467. Epub 2019 Mar 21.

PMID:
30561826
32.

Bax inhibitor 1 is a γ-secretase-independent presenilin-binding protein.

Wu S, Song W, Wong CCL, Shi Y.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):141-147. doi: 10.1073/pnas.1810870116. Epub 2018 Dec 17.

33.

Three Level Thoracolumbar Spondylectomy for Recurrent Giant Cell Tumour of the Spine: A Case Report.

Faruk NA, Mohd-Amin MZ, Awang-Ojep DN, Teo YY, Wong CC.

Malays Orthop J. 2018 Nov;12(3):50-52. doi: 10.5704/MOJ.1811.013.

34.

A novel strategy for isolation and purification of fucoxanthinol and fucoxanthin from the diatom Nitzschia laevis.

Sun P, Wong CC, Li Y, He Y, Mao X, Wu T, Ren Y, Chen F.

Food Chem. 2019 Mar 30;277:566-572. doi: 10.1016/j.foodchem.2018.10.133. Epub 2018 Nov 2.

PMID:
30502186
35.

HELLS Regulates Chromatin Remodeling and Epigenetic Silencing of Multiple Tumor Suppressor Genes in Human Hepatocellular Carcinoma.

Law CT, Wei L, Tsang FH, Chan CY, Xu IM, Lai RK, Ho DW, Lee JM, Wong CC, Ng IO, Wong CM.

Hepatology. 2019 May;69(5):2013-2030. doi: 10.1002/hep.30414. Epub 2019 Mar 27.

PMID:
30516846
36.

Architecture and subunit arrangement of the complete Saccharomyces cerevisiae COMPASS complex.

Wang Y, Ding Z, Liu X, Bao Y, Huang M, Wong CCL, Hong X, Cong Y.

Sci Rep. 2018 Nov 27;8(1):17405. doi: 10.1038/s41598-018-35609-8.

37.

DNA methylation of FKBP5 and response to exposure-based psychological therapy.

Roberts S, Keers R, Breen G, Coleman JRI, Jöhren P, Kepa A, Lester KJ, Margraf J, Scheider S, Teismann T, Wannemüller A, Eley TC, Wong CCY.

Am J Med Genet B Neuropsychiatr Genet. 2019 Mar;180(2):150-158. doi: 10.1002/ajmg.b.32650. Epub 2018 Oct 18.

39.

The Global Spine Care Initiative: care pathway for people with spine-related concerns.

Haldeman S, Johnson CD, Chou R, Nordin M, Côté P, Hurwitz EL, Green BN, Cedraschi C, Acaroğlu E, Kopansky-Giles D, Ameis A, Adjei-Kwayisi A, Ayhan S, Blyth F, Borenstein D, Brady O, Brooks P, Camilleri C, Castellote JM, Clay MB, Davatchi F, Dunn R, Goertz C, Griffith EA, Hondras M, Kane EJ, Lemeunier N, Mayer J, Mmopelwa T, Modic M, Moss J, Mullerpatan R, Muteti E, Mwaniki L, Ngandeu-Singwe M, Outerbridge G, Randhawa K, Shearer H, Sönmez E, Torres C, Torres P, Verville L, Vlok A, Watters W 3rd, Wong CC, Yu H.

Eur Spine J. 2018 Sep;27(Suppl 6):901-914. doi: 10.1007/s00586-018-5721-y. Epub 2018 Aug 27.

PMID:
30151811
40.

The Global Spine Care Initiative: World Spine Care executive summary on reducing spine-related disability in low- and middle-income communities.

Haldeman S, Nordin M, Chou R, Côté P, Hurwitz EL, Johnson CD, Randhawa K, Green BN, Kopansky-Giles D, Acaroğlu E, Ameis A, Cedraschi C, Aartun E, Adjei-Kwayisi A, Ayhan S, Aziz A, Bas T, Blyth F, Borenstein D, Brady O, Brooks P, Camilleri C, Castellote JM, Clay MB, Davatchi F, Dudler J, Dunn R, Eberspaecher S, Emmerich J, Farcy JP, Fisher-Jeffes N, Goertz C, Grevitt M, Griffith EA, Hajjaj-Hassouni N, Hartvigsen J, Hondras M, Kane EJ, Laplante J, Lemeunier N, Mayer J, Mior S, Mmopelwa T, Modic M, Moss J, Mullerpatan R, Muteti E, Mwaniki L, Ngandeu-Singwe M, Outerbridge G, Rajasekaran S, Shearer H, Smuck M, Sönmez E, Tavares P, Taylor-Vaisey A, Torres C, Torres P, van der Horst A, Verville L, Vialle E, Kumar GV, Vlok A, Watters W 3rd, Wong CC, Wong JJ, Yu H, Yüksel S.

Eur Spine J. 2018 Sep;27(Suppl 6):776-785. doi: 10.1007/s00586-018-5722-x. Epub 2018 Aug 27.

PMID:
30151809
41.

The Global Spine Care Initiative: methodology, contributors, and disclosures.

Johnson CD, Haldeman S, Nordin M, Chou R, Côté P, Hurwitz EL, Green BN, Kopansky-Giles D, Randhawa K, Cedraschi C, Ameis A, Acaroğlu E, Aartun E, Adjei-Kwayisi A, Ayhan S, Aziz A, Bas T, Blyth F, Borenstein D, Brady O, Brooks P, Camilleri C, Castellote JM, Clay MB, Davatchi F, Dudler J, Dunn R, Eberspaecher S, Emmerich J, Farcy JP, Fisher-Jeffes N, Goertz C, Grevitt M, Griffith EA, Hajjaj-Hassouni N, Hartvigsen J, Hondras M, Kane EJ, Laplante J, Lemeunier N, Mayer J, Mior S, Mmopelwa T, Modic M, Moss J, Mullerpatan R, Muteti E, Mwaniki L, Ngandeu-Singwe M, Outerbridge G, Rajasekaran S, Shearer H, Smuck M, Sönmez E, Tavares P, Taylor-Vaisey A, Torres C, Torres P, van der Horst A, Verville L, Vialle E, Kumar GV, Vlok A, Watters W 3rd, Wong CC, Wong JJ, Yu H, Yüksel S.

Eur Spine J. 2018 Sep;27(Suppl 6):786-795. doi: 10.1007/s00586-018-5723-9. Epub 2018 Aug 27.

PMID:
30151808
42.

The Global Spine Care Initiative: model of care and implementation.

Johnson CD, Haldeman S, Chou R, Nordin M, Green BN, Côté P, Hurwitz EL, Kopansky-Giles D, Acaroğlu E, Cedraschi C, Ameis A, Randhawa K, Aartun E, Adjei-Kwayisi A, Ayhan S, Aziz A, Bas T, Blyth F, Borenstein D, Brady O, Brooks P, Camilleri C, Castellote JM, Clay MB, Davatchi F, Dudler J, Dunn R, Eberspaecher S, Emmerich J, Farcy JP, Fisher-Jeffes N, Goertz C, Grevitt M, Griffith EA, Hajjaj-Hassouni N, Hartvigsen J, Hondras M, Kane EJ, Laplante J, Lemeunier N, Mayer J, Mior S, Mmopelwa T, Modic M, Moss J, Mullerpatan R, Muteti E, Mwaniki L, Ngandeu-Singwe M, Outerbridge G, Rajasekaran S, Shearer H, Smuck M, Sönmez E, Tavares P, Taylor-Vaisey A, Torres C, Torres P, van der Horst A, Verville L, Vialle E, Kumar GV, Vlok A, Watters W 3rd, Wong CC, Wong JJ, Yu H, Yüksel S.

Eur Spine J. 2018 Sep;27(Suppl 6):925-945. doi: 10.1007/s00586-018-5720-z. Epub 2018 Aug 27.

PMID:
30151805
43.

The Global Spine Care Initiative: resources to implement a spine care program.

Kopansky-Giles D, Johnson CD, Haldeman S, Chou R, Côté P, Green BN, Nordin M, Acaroğlu E, Ameis A, Cedraschi C, Hurwitz EL, Ayhan S, Borenstein D, Brady O, Brooks P, Davatchi F, Dunn R, Goertz C, Hajjaj-Hassouni N, Hartvigsen J, Hondras M, Lemeunier N, Mayer J, Mior S, Moss J, Mullerpatan R, Muteti E, Mwaniki L, Ngandeu-Singwe M, Outerbridge G, Randhawa K, Torres C, Torres P, Vlok A, Wong CC.

Eur Spine J. 2018 Sep;27(Suppl 6):915-924. doi: 10.1007/s00586-018-5725-7. Epub 2018 Aug 27.

PMID:
30151804
44.

Characterizing genetic and environmental influences on variable DNA methylation using monozygotic and dizygotic twins.

Hannon E, Knox O, Sugden K, Burrage J, Wong CCY, Belsky DW, Corcoran DL, Arseneault L, Moffitt TE, Caspi A, Mill J.

PLoS Genet. 2018 Aug 9;14(8):e1007544. doi: 10.1371/journal.pgen.1007544. eCollection 2018 Aug.

45.

FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p.

Zhang J, Zhou Y, Huang T, Wu F, Pan Y, Dong Y, Wang Y, Chan AKY, Liu L, Kwan JSH, Cheung AHK, Wong CC, Lo AKF, Cheng ASL, Yu J, Lo KW, Kang W, To KF.

Oncogene. 2019 Jan;38(1):33-46. doi: 10.1038/s41388-018-0430-x. Epub 2018 Aug 6.

46.

CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis.

Li W, Wong CC, Zhang X, Kang W, Nakatsu G, Zhao Q, Chen H, Go MYY, Chiu PWY, Wang X, Ji J, Li X, Cai Z, Ng EKW, Yu J.

Oncogene. 2018 Dec;37(50):6383-6398. doi: 10.1038/s41388-018-0402-1. Epub 2018 Jul 27.

47.

Examining HIV-Related stigma in relation to pain interference and psychological inflexibility among persons living with HIV/AIDS: The role of anxiety sensitivity.

Wong CCY, Paulus DJ, Lemaire C, Leonard A, Sharp C, Neighbors C, Brandt CP, Lu Q, Zvolensky MJ.

J HIV AIDS Soc Serv. 2018;17(1):1-15. doi: 10.1080/15381501.2017.1370680. Epub 2017 Nov 30.

48.

Relationships of Age and Sex with Cytokine Content and Distribution in Human Platelet Fibrin Gels.

Bai MY, Chuang MH, Lin MF, Tang SL, Wong CC, Chan WP.

Sci Rep. 2018 Jul 13;8(1):10642. doi: 10.1038/s41598-018-28376-z.

49.

Prenatal immune activation alters the adult neural epigenome but can be partly stabilised by a n-3 polyunsaturated fatty acid diet.

Basil P, Li Q, Gui H, Hui TCK, Ling VHM, Wong CCY, Mill J, McAlonan GM, Sham PC.

Transl Psychiatry. 2018 Jul 2;8(1):125. doi: 10.1038/s41398-018-0167-x.

50.

Introduction.

Wong CC, Yu J.

Adv Exp Med Biol. 2018;1061:1-2. doi: 10.1007/978-981-10-8684-7_1.

PMID:
29956202

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