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New cytotoxic polyacetylene alcohols from the Egyptian marine sponge Siphonochalina siphonella.

Ki DW, El-Desoky AH, Wong CP, Abdel-Ghani M, El-Beih AA, Mizuguchi M, Morita H.

J Nat Med. 2019 Dec 13. doi: 10.1007/s11418-019-01377-6. [Epub ahead of print]


Febrile neutropenia and its associated hospitalization in breast cancer patients on docetaxel-containing regimen: A retrospective cohort study on duration of prophylactic GCSF administration.

Lee CF, Zhou K, Young WM, Wong CS, Ng TY, Lee SF, Leung K, Wong LKM, So KH, Tang W, Chong G, Chan SK, Yip YTE, Ma VYM, Yeung A, Chin CHY, Kwan MW, Tsang HT.

Support Care Cancer. 2019 Dec 12. doi: 10.1007/s00520-019-05111-6. [Epub ahead of print]


Topical application of Chinese herbal medicine DAEP relieves the osteoarthritic knee pain in rats.

Siu WS, Shum WT, Cheng W, Wong CW, Shiu HT, Ko CH, Leung PC, Lam CWK, Wong CK.

Chin Med. 2019 Dec 9;14:55. doi: 10.1186/s13020-019-0278-1. eCollection 2019.


Statin use and the risk of renal cell carcinoma: national cohort study.

Chou YC, Lin CH, Wong CS, Chou WY, Chang JY, Sun CA.

J Investig Med. 2019 Dec 9. pii: jim-2019-001209. doi: 10.1136/jim-2019-001209. [Epub ahead of print]


Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway.

Kung-Chun Chiu D, Pui-Wah Tse A, Law CT, Ming-Jing Xu I, Lee D, Chen M, Kit-Ho Lai R, Wai-Hin Yuen V, Wing-Sum Cheu J, Wai-Hung Ho D, Wong CM, Zhang H, Oi-Lin Ng I, Chak-Lui Wong C.

Cell Death Dis. 2019 Dec 9;10(12):934. doi: 10.1038/s41419-019-2155-3.


ELEMENT TRIAL: study protocol for a randomized controlled trial on endoscopic ultrasound-guided biliary drainage of first intent with a lumen-apposing metal stent vs. endoscopic retrograde cholangio-pancreatography in the management of malignant distal biliary obstruction.

Chen YI, Callichurn K, Chatterjee A, Desilets E, Fergal D, Forbes N, Gan I, Kenshil S, Khashab MA, Kunda R, Lam E, May G, Mohamed R, Mosko J, Paquin SC, Sahai A, Sandha G, Teshima C, Barkun A, Barkun J, Bessissow A, Candido K, Martel M, Miller C, Waschke K, Zogopoulos G, Wong C; ELEMENT trial and for the Canadian Endoscopic Research Collaborative (CERC).

Trials. 2019 Dec 9;20(1):696. doi: 10.1186/s13063-019-3918-y.


A systematic review of older adults' request for or attitude toward euthanasia or assisted-suicide.

Castelli Dransart DA, Lapierre S, Erlangsen A, Canetto SS, Heisel M, Draper B, Lindner R, Richard-Devantoy S, Cheung G, Scocco P, Gusmão R, De Leo D, Inoue K, De Techterman V, Fiske A, Hong JP, Landry M, Lepage AA, Marcoux I, Na PJ, Neufeld E, Ummel D, Winslov JH, Wong C, Wu J, Wyart M.

Aging Ment Health. 2019 Dec 10:1-11. doi: 10.1080/13607863.2019.1697201. [Epub ahead of print]


In Vitro Expansion of Keratinocytes on Human Dermal Fibroblast-Derived Matrix Retains Their Stem-Like Characteristics.

Wong CW, LeGrand CF, Kinnear BF, Sobota RM, Ramalingam R, Dye DE, Raghunath M, Lane EB, Coombe DR.

Sci Rep. 2019 Dec 6;9(1):18561. doi: 10.1038/s41598-019-54793-9.


Imbalance in the force: the dark side of the microbiota on stroke risk and progression.

Prame Kumar K, Wong CH.

Curr Opin Neurobiol. 2019 Dec 3;62:10-16. doi: 10.1016/j.conb.2019.10.002. [Epub ahead of print] Review.


Converting waste lignin into nano-biochar as a renewable substitute of carbon black for reinforcing styrene-butadiene rubber.

Jiang C, Bo J, Xiao X, Zhang S, Wang Z, Yan G, Wu Y, Wong C, He H.

Waste Manag. 2019 Dec 2;102:732-742. doi: 10.1016/j.wasman.2019.11.019. [Epub ahead of print]


Novel Fecobionics Defecatory Function Testing.

Gregersen H, Chen SC, Leung WW, Wong C, Mak T, Ng S, Futaba K.

Clin Transl Gastroenterol. 2019 Nov 27. doi: 10.14309/ctg.0000000000000108. [Epub ahead of print]


Biochemical sensing in graphene-enhanced microfiber resonators with individual molecule sensitivity and selectivity.

Cao Z, Yao B, Qin C, Yang R, Guo Y, Zhang Y, Wu Y, Bi L, Chen Y, Xie Z, Peng G, Huang SW, Wong CW, Rao Y.

Light Sci Appl. 2019 Nov 22;8:107. doi: 10.1038/s41377-019-0213-3. eCollection 2019.


Using Transcriptional Signatures to Find Cancer Drivers with LURE.

Haan D, Tao R, Friedl V, Anastopoulos IN, Wong CK, Weinstein AS, Stuart JM.

Pac Symp Biocomput. 2020;25:343-354.


Wastewater sources of per- and polyfluorinated alkyl substances (PFAS) and pharmaceuticals in four Canadian Arctic communities.

Stroski KM, Luong KH, Challis JK, Chaves-Barquero LG, Hanson ML, Wong CS.

Sci Total Environ. 2019 Nov 29:134494. doi: 10.1016/j.scitotenv.2019.134494. [Epub ahead of print]


Effectiveness of a Brief Self-determination Theory-Based Smoking Cessation Intervention for Smokers at Emergency Departments in Hong Kong: A Randomized Clinical Trial.

Li WHC, Ho KY, Wang MP, Cheung DYT, Lam KKW, Xia W, Cheung KY, Wong CKH, Chan SSC, Lam TH.

JAMA Intern Med. 2019 Dec 2. doi: 10.1001/jamainternmed.2019.5176. [Epub ahead of print]


Surface roughness influences the protein corona formation of glycosylated nanoparticles and alter their cellular uptake.

Piloni A, Wong CK, Chen F, Lord M, Walther A, Stenzel MH.

Nanoscale. 2019 Dec 28;11(48):23259-23267. doi: 10.1039/c9nr06835j. Epub 2019 Nov 29.


Zinc finger protein 5 (ZFP5) associates with ethylene signaling to regulate the phosphate and potassium deficiency-induced root hair development in Arabidopsis.

Huang L, Jiang Q, Wu J, An L, Zhou Z, Wong C, Wu M, Yu H, Gan Y.

Plant Mol Biol. 2019 Nov 28. doi: 10.1007/s11103-019-00937-4. [Epub ahead of print]


Tsc1-mTORC1 signaling controls striatal dopamine release and cognitive flexibility.

Kosillo P, Doig NM, Ahmed KM, Agopyan-Miu AHCW, Wong CD, Conyers L, Threlfell S, Magill PJ, Bateup HS.

Nat Commun. 2019 Nov 28;10(1):5426. doi: 10.1038/s41467-019-13396-8.


Emotion Dysregulation: An Explanatory Construct in the Relation Between HIV-Related Stigma and Hazardous Drinking among Persons Living with HIV/AIDS.

Wong CCY, Paulus DJ, Lemaire C, Leonard A, Sharp C, Neighbors C, Brandt CP, Zvolensky MJ.

Stigma Health. 2019 Aug;4(3):293-299. doi: 10.1037/sah0000113. Epub 2018 Jun 7.


From mental representations to neural codes: A multilevel approach.

Gauthier J, Loula J, Pollock E, Wilson TB, Wong C.

Behav Brain Sci. 2019 Nov 28;42:e228. doi: 10.1017/S0140525X19001390.


Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer's disease mice.

Jew K, Herr D, Wong C, Kennell A, Morris-Schaffer K, Oberdörster G, O'Banion MK, Cory-Slechta DA, Elder A.

Part Fibre Toxicol. 2019 Nov 26;16(1):45. doi: 10.1186/s12989-019-0323-3.


Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein.

Woodring J, Lu SH, Krasnova L, Wang SC, Chen JB, Chou CC, Huang YC, Cheng TJ, Wu YT, Chen YH, Fang JM, Tsai MD, Wong CH.

J Med Chem. 2019 Nov 26. doi: 10.1021/acs.jmedchem.9b01244. [Epub ahead of print]


Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age.

Zito A, Davies MN, Tsai PC, Roberts S, Andres-Ejarque R, Nardone S, Bell JT, Wong CCY, Small KS.

Nat Commun. 2019 Nov 25;10(1):5339. doi: 10.1038/s41467-019-13340-w.


Overexpression, purification, enzymatic and microscopic characterization of recombinant mycobacterial F-ATP synthase.

Saw WG, Wong CF, Dick T, Grüber G.

Biochem Biophys Res Commun. 2019 Nov 21. pii: S0006-291X(19)32224-7. doi: 10.1016/j.bbrc.2019.11.098. [Epub ahead of print]


Physical methods for mechanistic understanding: general discussion.

Aoki Y, Bauer M, Braun T, Cadge J, Davies D, Durand DJ, Eisenstein O, Ess D, Fairlamb I, Fey N, Gallarati S, George M, Greaves M, Halse M, Hamilton A, Harvey J, Haynes A, Hintermair U, Hulme AN, Ishii Y, Jakoobi M, Jensen VR, Kennepohl P, Kuwata S, Lei A, Lloyd-Jones G, Love J, Lovelock K, Lynam J, Macgregor S, Marder TB, Meijer EJ, Morgan P, Morris RH, Mwansa J, Nelson D, Odom A, Perutz R, Reiher M, Renny J, Roithová J, Schafer L, Schilter D, Scott S, Slattery J, Walton J, Wilden JD, Wong CY, Yaman T, Young T.

Faraday Discuss. 2019 Dec 2;220(0):144-178. doi: 10.1039/C9FD90070E. No abstract available.


Understanding unusual element-element bond formation and activation: general discussion.

Aoki Y, Braun T, Davies D, Eisenstein O, Fairlamb I, Fey N, George M, Goult C, Hamilton A, Huang Z, Ishii Y, Jakoobi M, Kuwata S, Lloyd-Jones G, Love J, Lynam J, Macgregor S, Marder TB, Morgan P, Mwansa J, Odom A, Perutz R, Reiher M, Slattery J, Talavera M, Thomas G, Wong CY.

Faraday Discuss. 2019 Dec 2;220(0):376-385. doi: 10.1039/C9FD90071C. No abstract available.


Mechanistic insight into organic and industrial transformations: general discussion.

Aoki Y, Bauer M, Braun T, Cadge JA, Clarke GE, Durand DJ, Eisenstein O, Gallarati S, Greaves M, Harvey J, Haynes A, Hintermair U, Hulme AN, Ishii Y, Jakoobi M, Jensen VR, Kennepohl P, Kuwata S, Lei A, Lloyd-Jones G, Love J, Lynam J, Macgregor S, Morris RH, Nelson D, Odom A, Perutz R, Reiher M, Renny J, Roithova J, Schafer L, Scott S, Seavill PW, Slattery J, Takao T, Walton J, Wilden JD, Wong CY, Young T.

Faraday Discuss. 2019 Dec 2;220(0):282-316. doi: 10.1039/C9FD90072A. No abstract available.


Engineering pyrolysis biochar via single-step microwave steam activation for hazardous landfill leachate treatment.

Lam SS, Yek PNY, Ok YS, Chong CC, Liew RK, Tsang DCW, Park YK, Liu Z, Wong CS, Peng W.

J Hazard Mater. 2019 Nov 12:121649. doi: 10.1016/j.jhazmat.2019.121649. [Epub ahead of print]


Macromolecular dextran sulfate facilitates extracellular matrix deposition by electrostatic interaction independent from a macromolecular crowding effect.

Assunção M, Wong CW, Richardson JJ, Tsang R, Beyer S, Raghunath M, Blocki A.

Mater Sci Eng C Mater Biol Appl. 2020 Jan;106:110280. doi: 10.1016/j.msec.2019.110280. Epub 2019 Oct 7.


Global Lifetime and 12-Month Prevalence of Suicidal Behavior, Deliberate Self-Harm and Non-Suicidal Self-Injury in Children and Adolescents between 1989 and 2018: A Meta-Analysis.

Lim KS, Wong CH, McIntyre RS, Wang J, Zhang Z, Tran BX, Tan W, Ho CS, Ho RC.

Int J Environ Res Public Health. 2019 Nov 19;16(22). pii: E4581. doi: 10.3390/ijerph16224581.


A community-based lung cancer rapid tissue donation protocol provides high-quality drug-resistant specimens for proteogenomic analyses.

Boyle TA, Quinn GP, Schabath MB, Muñoz-Antonia T, Saller JJ, Duarte LF, Hair LS, Teer JK, Chiang DY, Leary R, Wong CC, Savchenko A, Singh AP, Charette L, Mendell K, Gorgun G, Antonia SJ, Chiappori AA, Creelan BC, Gray JE, Haura EB.

Cancer Med. 2019 Nov 20. doi: 10.1002/cam4.2670. [Epub ahead of print]


Unique structural and mechanistic properties of mycobacterial F-ATP synthases: Implications for drug design.

Kamariah N, Ragunathan P, Shin J, Saw WG, Wong CF, Dick T, Grüber G.

Prog Biophys Mol Biol. 2019 Nov 16. pii: S0079-6107(19)30192-0. doi: 10.1016/j.pbiomolbio.2019.11.006. [Epub ahead of print] Review.


Bisphenol compounds regulate decidualized stromal cells in modulating trophoblastic spheroid outgrowth and invasion in vitro.

Fan H, Jiang L, Lee YL, Wong CKC, Ng EHY, Yeung WSB, Lee KF.

Biol Reprod. 2019 Nov 19. pii: ioz212. doi: 10.1093/biolre/ioz212. [Epub ahead of print]


Inhibition of food craving is a metabolically active process in the brain in obese men.

Wang GJ, Shokri Kojori E, Yuan K, Wiers CE, Manza P, Wong CT, Fowler JS, Volkow ND.

Int J Obes (Lond). 2019 Nov 18. doi: 10.1038/s41366-019-0484-z. [Epub ahead of print]


Modular platforms for the assembly of self-adjuvanting lipopeptide-based vaccines for use in an out-bred population.

Zeng W, Horrocks KJ, Tan ACL, Wong CY, Chua BY, Jackson DC.

Vaccine. 2019 Nov 15. pii: S0264-410X(19)31435-5. doi: 10.1016/j.vaccine.2019.10.055. [Epub ahead of print]


Metabolic Regulation of Hippocampal Neuroprogenitor Apoptosis After Irradiation.

Li YQ, Koritzinsky M, Wong CS.

J Neuropathol Exp Neurol. 2019 Oct 19. pii: nlz108. doi: 10.1093/jnen/nlz108. [Epub ahead of print]


Survival and Prognostic Factors in C9orf72 Repeat Expansion Carriers: A Systematic Review and Meta-analysis.

Glasmacher SA, Wong C, Pearson IE, Pal S.

JAMA Neurol. 2019 Nov 18. doi: 10.1001/jamaneurol.2019.3924. [Epub ahead of print]


Stakeholder engagement in research: a scoping review of current evaluation methods.

Martinez J, Wong C, Piersol CV, Bieber DC, Perry BL, Leland NE.

J Comp Eff Res. 2019 Nov;8(15):1327-1341. doi: 10.2217/cer-2019-0047. Epub 2019 Nov 18.


Adult Drosophila Lack Hematopoiesis but Rely on a Blood Cell Reservoir at the Respiratory Epithelia to Relay Infection Signals to Surrounding Tissues.

Sanchez Bosch P, Makhijani K, Herboso L, Gold KS, Baginsky R, Woodcock KJ, Alexander B, Kukar K, Corcoran S, Jacobs T, Ouyang D, Wong C, Ramond EJV, Rhiner C, Moreno E, Lemaitre B, Geissmann F, Brückner K.

Dev Cell. 2019 Nov 14. pii: S1534-5807(19)30864-0. doi: 10.1016/j.devcel.2019.10.017. [Epub ahead of print]


Reliability of ranking anesthesiologists and nurse anesthetists using leniency-adjusted clinical supervision and work habits scores.

Dexter F, Bayman EO, Wong CA, Hindman BJ.

J Clin Anesth. 2019 Nov 15:109639. doi: 10.1016/j.jclinane.2019.109639. [Epub ahead of print]


Clinical outcome and toxicity for immunotherapy treatment in metastatic cancer patients.

Lau KS, Liu R, Wong CC, Siu WKS, Yuen KK.

Ann Palliat Med. 2019 Nov 12. pii: apm.2019.10.03. doi: 10.21037/apm.2019.10.03. [Epub ahead of print]


Guideline-Based Critical Care Pathway Improves Long-Term Clinical Outcomes in Patients with Acute Coronary Syndrome.

Hai JJ, Wong CK, Un KC, Wong KL, Zhang ZY, Chan PH, Lam YM, Chan WS, Lam CC, Tam CC, Wong YT, Yung SY, Chan KW, Siu CW, Lau CP, Tse HF.

Sci Rep. 2019 Nov 14;9(1):16814. doi: 10.1038/s41598-019-53348-2.


Exclusion of unsuitable CNS drug candidates based on their physicochemical properties and unbound fractions in biomatrices for brain microdialysis investigations.

Wang Q, Ren T, Zhao J, Wong CH, Chan HYE, Zuo Z.

J Pharm Biomed Anal. 2020 Jan 30;178:112946. doi: 10.1016/j.jpba.2019.112946. Epub 2019 Oct 25.


DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression.

Resnick R, Wong CJ, Hamm DC, Bennett SR, Skene PJ, Hake SB, Henikoff S, van der Maarel SM, Tapscott SJ.

Cell Rep. 2019 Nov 12;29(7):1812-1820.e5. doi: 10.1016/j.celrep.2019.10.025.


RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation.

Saffari A, Arno M, Nasser E, Ronald A, Wong CCY, Schalkwyk LC, Mill J, Dudbridge F, Meaburn EL.

Mol Autism. 2019 Nov 7;10:38. doi: 10.1186/s13229-019-0285-1. eCollection 2019.


Bio-nanotechnological advancement of orally administered insulin nanoparticles: Comprehensive review of experimental design for physicochemical characterization.

Wong CY, Luna G, Martinez J, Al-Salami H, Dass CR.

Int J Pharm. 2019 Dec 15;572:118720. doi: 10.1016/j.ijpharm.2019.118720. Epub 2019 Nov 9. Review.


Creation of Si quantum dots in a silica matrix due to conversion of radiation defects under pulsed ion-beam exposure.

Zatsepin AF, Kuznetsova YA, Wong CH.

Phys Chem Chem Phys. 2019 Dec 7;21(45):25467-25473. doi: 10.1039/c9cp04715h. Epub 2019 Nov 12.


Brain activity mediators of PTSD symptom reduction during real-time fMRI amygdala neurofeedback emotional training.

Misaki M, Phillips R, Zotev V, Wong CK, Wurfel BE, Krueger F, Feldner M, Bodurka J.

Neuroimage Clin. 2019;24:102047. doi: 10.1016/j.nicl.2019.102047. Epub 2019 Oct 22.


Stroke Severity, and Not Cerebral Infarct Location, Increases the Risk of Infection.

Shim R, Wen SW, Wanrooy BJ, Rank M, Thirugnanachandran T, Ho L, Sepehrizadeh T, de Veer M, Srikanth VK, Ma H, Phan TG, Sobey CG, Wong CHY.

Transl Stroke Res. 2019 Nov 10. doi: 10.1007/s12975-019-00738-3. [Epub ahead of print]


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