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Items: 7


Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa.

Cooper SJ, Krishnamoorthy G, Wolloscheck D, Walker JK, Rybenkov VV, Parks JM, Zgurskaya HI.

ACS Infect Dis. 2018 Aug 10;4(8):1223-1234. doi: 10.1021/acsinfecdis.8b00036. Epub 2018 May 25.


Kinetic Control of Quorum Sensing in Pseudomonas aeruginosa by Multidrug Efflux Pumps.

Wolloscheck D, Krishnamoorthy G, Nguyen J, Zgurskaya HI.

ACS Infect Dis. 2018 Feb 9;4(2):185-195. doi: 10.1021/acsinfecdis.7b00160. Epub 2017 Nov 10.


Synergy between Active Efflux and Outer Membrane Diffusion Defines Rules of Antibiotic Permeation into Gram-Negative Bacteria.

Krishnamoorthy G, Leus IV, Weeks JW, Wolloscheck D, Rybenkov VV, Zgurskaya HI.

mBio. 2017 Oct 31;8(5). pii: e01172-17. doi: 10.1128/mBio.01172-17.


Bifurcation kinetics of drug uptake by Gram-negative bacteria.

Westfall DA, Krishnamoorthy G, Wolloscheck D, Sarkar R, Zgurskaya HI, Rybenkov VV.

PLoS One. 2017 Sep 19;12(9):e0184671. doi: 10.1371/journal.pone.0184671. eCollection 2017.


Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux Pump.

Abdali N, Parks JM, Haynes KM, Chaney JL, Green AT, Wolloscheck D, Walker JK, Rybenkov VV, Baudry J, Smith JC, Zgurskaya HI.

ACS Infect Dis. 2017 Jan 13;3(1):89-98. doi: 10.1021/acsinfecdis.6b00167. Epub 2016 Nov 2.


Breaking the Permeability Barrier of Escherichia coli by Controlled Hyperporination of the Outer Membrane.

Krishnamoorthy G, Wolloscheck D, Weeks JW, Croft C, Rybenkov VV, Zgurskaya HI.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7372-7381. Print 2016 Dec.


Mechanism of coupling drug transport reactions located in two different membranes.

Zgurskaya HI, Weeks JW, Ntreh AT, Nickels LM, Wolloscheck D.

Front Microbiol. 2015 Feb 24;6:100. doi: 10.3389/fmicb.2015.00100. eCollection 2015. Review.

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