Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 376

1.

Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells.

Zhang E, Mohammed Al-Amily I, Mohammed S, Luan C, Asplund O, Ahmed M, Ye Y, Ben-Hail D, Soni A, Vishnu N, Bompada P, De Marinis Y, Groop L, Shoshan-Barmatz V, Renström E, Wollheim CB, Salehi A.

Cell Metab. 2019 Jan 8;29(1):64-77.e6. doi: 10.1016/j.cmet.2018.09.008. Epub 2018 Oct 4.

2.

Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells.

Taneera J, Prasad RB, Dhaiban S, Mohammed AK, Haataja L, Arvan P, Hamad M, Groop L, Wollheim CB.

Mol Cell Endocrinol. 2018 Sep 5;472:10-17. doi: 10.1016/j.mce.2018.06.003. Epub 2018 Jun 8.

PMID:
29890211
3.

The Association of Mediterranean and DASH Diets with Mortality in Adults on Hemodialysis: The DIET-HD Multinational Cohort Study.

Saglimbene VM, Wong G, Craig JC, Ruospo M, Palmer SC, Campbell K, Garcia-Larsen V, Natale P, Teixeira-Pinto A, Carrero JJ, Stenvinkel P, Gargano L, Murgo AM, Johnson DW, Tonelli M, Gelfman R, Celia E, Ecder T, Bernat AG, Del Castillo D, Timofte D, Török M, Bednarek-Skublewska A, Duława J, Stroumza P, Hoischen S, Hansis M, Fabricius E, Felaco P, Wollheim C, Hegbrant J, Strippoli GFM.

J Am Soc Nephrol. 2018 Jun;29(6):1741-1751. doi: 10.1681/ASN.2018010008. Epub 2018 Apr 25.

PMID:
29695436
4.

Dietary n-3 polyunsaturated fatty acid intake and all-cause and cardiovascular mortality in adults on hemodialysis: The DIET-HD multinational cohort study.

Saglimbene VM, Wong G, Ruospo M, Palmer SC, Campbell K, Larsen VG, Natale P, Teixeira-Pinto A, Carrero JJ, Stenvinkel P, Gargano L, Murgo AM, Johnson DW, Tonelli M, Gelfman R, Celia E, Ecder T, Bernat AG, Del Castillo D, Timofte D, Török M, Bednarek-Skublewska A, Duława J, Stroumza P, Hoischen S, Hansis M, Fabricius E, Wollheim C, Hegbrant J, Craig JC, Strippoli GFM.

Clin Nutr. 2019 Feb;38(1):429-437. doi: 10.1016/j.clnu.2017.11.020. Epub 2017 Dec 6.

5.

Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase.

Andersson LE, Shcherbina L, Al-Majdoub M, Vishnu N, Arroyo CB, Aste Carrara J, Wollheim CB, Fex M, Mulder H, Wierup N, Spégel P.

Diabetes. 2018 Mar;67(3):372-384. doi: 10.2337/db16-1441. Epub 2017 Dec 11.

6.

Prevalence and patterns of cognitive impairment in adult hemodialysis patients: the COGNITIVE-HD study.

van Zwieten A, Wong G, Ruospo M, Palmer SC, Barulli MR, Iurillo A, Saglimbene V, Natale P, Gargano L, Murgo M, Loy CT, Tortelli R, Craig JC, Johnson DW, Tonelli M, Hegbrant J, Wollheim C, Logroscino G, Strippoli GFM; COGNITIVE-HD study investigators.

Nephrol Dial Transplant. 2018 Jul 1;33(7):1197-1206. doi: 10.1093/ndt/gfx314.

PMID:
29186522
7.

The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects β-cells against stress-induced apoptosis.

Baquié M, St-Onge L, Kerr-Conte J, Cobo-Vuilleumier N, Lorenzo PI, Jimenez Moreno CM, Cederroth CR, Nef S, Borot S, Bosco D, Wang H, Marchetti P, Pattou F, Wollheim CB, Gauthier BR.

Hum Mol Genet. 2018 Jan 15;27(2):406. doi: 10.1093/hmg/ddx402. No abstract available.

PMID:
29186426
8.

Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes.

Solimena M, Schulte AM, Marselli L, Ehehalt F, Richter D, Kleeberg M, Mziaut H, Knoch KP, Parnis J, Bugliani M, Siddiq A, Jörns A, Burdet F, Liechti R, Suleiman M, Margerie D, Syed F, Distler M, Grützmann R, Petretto E, Moreno-Moral A, Wegbrod C, Sönmez A, Pfriem K, Friedrich A, Meinel J, Wollheim CB, Baretton GB, Scharfmann R, Nogoceke E, Bonifacio E, Sturm D, Meyer-Puttlitz B, Boggi U, Saeger HD, Filipponi F, Lesche M, Meda P, Dahl A, Wigger L, Xenarios I, Falchi M, Thorens B, Weitz J, Bokvist K, Lenzen S, Rutter GA, Froguel P, von Bülow M, Ibberson M, Marchetti P.

Diabetologia. 2018 Mar;61(3):641-657. doi: 10.1007/s00125-017-4500-3. Epub 2017 Nov 28.

9.

Sulforaphane improves disrupted ER-mitochondria interactions and suppresses exaggerated hepatic glucose production.

Tubbs E, Axelsson AS, Vial G, Wollheim CB, Rieusset J, Rosengren AH.

Mol Cell Endocrinol. 2018 Feb 5;461:205-214. doi: 10.1016/j.mce.2017.09.016. Epub 2017 Sep 18.

PMID:
28923347
10.

The prevalence and correlates of low sexual functioning in women on hemodialysis: A multinational, cross-sectional study.

Saglimbene V, Natale P, Palmer S, Scardapane M, Craig JC, Ruospo M, Gargano L, Lucisano G, Török M, Celia E, Gelfman R, Bednarek-Skublewska A, Dulawa J, Stroumza P, Leal M, Del Castillo D, Murgo AM, Schon S, Wollheim C, Hegbrant J, Strippoli GFM.

PLoS One. 2017 Jun 20;12(6):e0179511. doi: 10.1371/journal.pone.0179511. eCollection 2017.

11.

Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes.

Axelsson AS, Tubbs E, Mecham B, Chacko S, Nenonen HA, Tang Y, Fahey JW, Derry JMJ, Wollheim CB, Wierup N, Haymond MW, Friend SH, Mulder H, Rosengren AH.

Sci Transl Med. 2017 Jun 14;9(394). pii: eaah4477. doi: 10.1126/scitranslmed.aah4477.

PMID:
28615356
12.

Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.

Axelsson AS, Mahdi T, Nenonen HA, Singh T, Hänzelmann S, Wendt A, Bagge A, Reinbothe TM, Millstein J, Yang X, Zhang B, Gusmao EG, Shu L, Szabat M, Tang Y, Wang J, Salö S, Eliasson L, Artner I, Fex M, Johnson JD, Wollheim CB, Derry JMJ, Mecham B, Spégel P, Mulder H, Costa IG, Zhang E, Rosengren AH.

Nat Commun. 2017 Jun 6;8:15652. doi: 10.1038/ncomms15652.

13.

Group B Streptococcus detection in pregnant women via culture and PCR methods.

Wollheim C, Sperhacke RD, Fontana SKR, Vanni AC, Kato SK, Araújo PR, Barth AL, Madi JM.

Rev Soc Bras Med Trop. 2017 Mar-Apr;50(2):179-183. doi: 10.1590/0037-8682-0454-2016.

14.

Periodontitis and early mortality among adults treated with hemodialysis: a multinational propensity-matched cohort study.

Ruospo M, Palmer SC, Wong G, Craig JC, Petruzzi M, De Benedittis M, Ford P, Johnson DW, Tonelli M, Natale P, Saglimbene V, Pellegrini F, Celia E, Gelfman R, Leal MR, Torok M, Stroumza P, Bednarek-Skublewska A, Dulawa J, Frantzen L, Del Castillo D, Schon S, Bernat AG, Hegbrant J, Wollheim C, Gargano L, Bots CP, Strippoli GF; ORALD Investigators.

BMC Nephrol. 2017 May 22;18(1):166. doi: 10.1186/s12882-017-0574-x.

15.

Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell.

Ofori JK, Salunkhe VA, Bagge A, Vishnu N, Nagao M, Mulder H, Wollheim CB, Eliasson L, Esguerra JL.

Sci Rep. 2017 Mar 23;7:44986. doi: 10.1038/srep44986.

16.

Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes.

Shcherbina L, Edlund A, Esguerra JL, Abels M, Zhou Y, Ottosson-Laakso E, Wollheim CB, Hansson O, Eliasson L, Wierup N.

Mol Cell Endocrinol. 2017 May 15;447:52-60. doi: 10.1016/j.mce.2017.02.027. Epub 2017 Feb 24.

PMID:
28237718
17.

Depression and all-cause and cardiovascular mortality in patients on haemodialysis: a multinational cohort study.

Saglimbene V, Palmer S, Scardapane M, Craig JC, Ruospo M, Natale P, Gargano L, Leal M, Bednarek-Skublewska A, Dulawa J, Ecder T, Stroumza P, Marco Murgo A, Schön S, Wollheim C, Hegbrant J, Strippoli GF.

Nephrol Dial Transplant. 2017 Feb 1;32(2):377-384. doi: 10.1093/ndt/gfw016.

PMID:
28186569
18.

Performance of a molecular assay to detect Mycobacterium tuberculosis complex DNA in clinical specimens: multicenter study in Brazil.

Verza M, Schmid KB, Barcellos RB, Linck N, Bello GL, Scapin D, Sperhacke RD, Silva MS, Wollheim C, Rivero MG, Kritski AL, Rezende L Jr, Oliveira MM, Costa ER, Rossetti ML.

Mem Inst Oswaldo Cruz. 2017 Feb;112(2):94-99. doi: 10.1590/0074-02760160196.

19.

Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes.

Ly LD, Xu S, Choi SK, Ha CM, Thoudam T, Cha SK, Wiederkehr A, Wollheim CB, Lee IK, Park KS.

Exp Mol Med. 2017 Feb 3;49(2):e291. doi: 10.1038/emm.2016.157. Review.

20.

Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ß-cells: A potential beneficial effect in the pre-diabetic state?

Pournourmohammadi S, Grimaldi M, Stridh MH, Lavallard V, Waagepetersen HS, Wollheim CB, Maechler P.

Int J Biochem Cell Biol. 2017 Jul;88:220-225. doi: 10.1016/j.biocel.2017.01.012. Epub 2017 Jan 27.

PMID:
28137482
21.

Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high-phosphate-induced mitochondrial oxidative stress and defective insulin secretion.

Nguyen TT, Quan X, Xu S, Das R, Cha SK, Kong ID, Shong M, Wollheim CB, Park KS.

FASEB J. 2016 Dec;30(12):3979-3988. Epub 2016 Aug 26.

PMID:
27565711
22.

Expression of Concern. Low Concentration of Interleukin-1β Induces FLICE-Inhibitory Protein-Mediated β-Cell Proliferation in Human Pancreatic Islets. Diabetes 2006;55:2713-2722; DOI: 10.2337/db05-1430.

Maedler K, Schumann DM, Sauter N, Ellingsgaard H, Bosco D, Baertschiger R, Iwakura Y, Oberholzer J, Wollheim CB, Gauthier BR, Donath MY.

Diabetes. 2016 Aug;65(8):2462. doi: 10.2337/db16-ec08a. No abstract available. Update in: Diabetes. 2018 Nov;67(11):2479-2480.

23.

CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.

Abels M, Riva M, Bennet H, Ahlqvist E, Dyachok O, Nagaraj V, Shcherbina L, Fred RG, Poon W, Sörhede-Winzell M, Fadista J, Lindqvist A, Kask L, Sathanoori R, Dekker-Nitert M, Kuhar MJ, Ahrén B, Wollheim CB, Hansson O, Tengholm A, Fex M, Renström E, Groop L, Lyssenko V, Wierup N.

Diabetologia. 2016 Sep;59(9):1928-37. doi: 10.1007/s00125-016-4020-6. Epub 2016 Jun 23.

PMID:
27338624
24.

Physiology: Microbial signals to the brain control weight.

Trajkovski M, Wollheim CB.

Nature. 2016 Jun 9;534(7606):185-7. doi: 10.1038/534185a. No abstract available.

PMID:
27279209
25.

Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes.

Prasad RB, Lessmark A, Almgren P, Kovacs G, Hansson O, Oskolkov N, Vitai M, Ladenvall C, Kovacs P, Fadista J, Lachmann M, Zhou Y, Sonestedt E, Poon W, Wollheim CB, Orho-Melander M, Stumvoll M, Tuomi T, Pääbo S, Koranyi L, Groop L.

Diabetologia. 2016 Aug;59(8):1702-13. doi: 10.1007/s00125-016-3973-9. Epub 2016 May 7.

PMID:
27155871
26.

Patterns of oral disease in adults with chronic kidney disease treated with hemodialysis.

Palmer SC, Ruospo M, Wong G, Craig JC, Petruzzi M, De Benedittis M, Ford P, Johnson DW, Tonelli M, Natale P, Saglimbene V, Pellegrini F, Celia E, Gelfman R, Leal MR, Torok M, Stroumza P, Frantzen L, Bednarek-Skublewska A, Dulawa J, Del Castillo D, Bernat AG, Hegbrant J, Wollheim C, Schon S, Gargano L, Bots CP, Strippoli GF; ORALD Investigators.

Nephrol Dial Transplant. 2016 Oct;31(10):1647-53. doi: 10.1093/ndt/gfv413. Epub 2015 Dec 29.

PMID:
27035674
27.

Is zinc an intra-islet regulator of glucagon secretion?

Ishihara H, Wollheim CB.

Diabetol Int. 2016 Feb 27;7(2):106-110. doi: 10.1007/s13340-016-0259-x. eCollection 2016 Jun.

28.

Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4α (HNF4Α) Is Vital to Beta-cell Function.

Moore BD, Jin RU, Lo H, Jung M, Wang H, Battle MA, Wollheim CB, Urano F, Mills JC.

J Biol Chem. 2016 Mar 18;291(12):6146-57. doi: 10.1074/jbc.M115.685750. Epub 2016 Jan 20.

29.

Thrombin stimulates insulin secretion via protease-activated receptor-3.

Hänzelmann S, Wang J, Güney E, Tang Y, Zhang E, Axelsson AS, Nenonen H, Salehi AS, Wollheim CB, Zetterberg E, Berntorp E, Costa IG, Castelo R, Rosengren AH.

Islets. 2015;7(4):e1118195. doi: 10.1080/19382014.2015.1118195.

30.

COGNITIVE-HD study: protocol of an observational study of neurocognitive functioning and association with clinical outcomes in adults with end-stage kidney disease treated with haemodialysis.

Palmer SC, Ruospo M, Barulli MR, Iurillo A, Saglimbene V, Natale P, Gargano L, Murgo AM, Loy C, van Zwieten A, Wong G, Tortelli R, Craig JC, Johnson DW, Tonelli M, Hegbrant J, Wollheim C, Logroscino G, Strippoli GF; COGNITIVE-HD Study Investigators.

BMJ Open. 2015 Dec 9;5(12):e009328. doi: 10.1136/bmjopen-2015-009328.

31.

Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stress.

Xu S, Nam SM, Kim JH, Das R, Choi SK, Nguyen TT, Quan X, Choi SJ, Chung CH, Lee EY, Lee IK, Wiederkehr A, Wollheim CB, Cha SK, Park KS.

Cell Death Dis. 2015 Nov 19;6:e1976. doi: 10.1038/cddis.2015.331.

32.

Dental Health and Mortality in People With End-Stage Kidney Disease Treated With Hemodialysis: A Multinational Cohort Study.

Palmer SC, Ruospo M, Wong G, Craig JC, Petruzzi M, De Benedittis M, Ford P, Johnson DW, Tonelli M, Natale P, Saglimbene V, Pellegrini F, Celia E, Gelfman R, Leal MR, Torok M, Stroumza P, Bednarek-Skublewska A, Dulawa J, Frantzen L, Ferrari JN, Del Castillo D, Bernat AG, Hegbrant J, Wollheim C, Gargano L, Bots CP, Strippoli GF; ORAL-D Study Investigators.

Am J Kidney Dis. 2015 Oct;66(4):666-76. doi: 10.1053/j.ajkd.2015.04.051. Epub 2015 Jun 25.

33.

Mitochondrial oxidative stress mediates high-phosphate-induced secretory defects and apoptosis in insulin-secreting cells.

Nguyen TT, Quan X, Hwang KH, Xu S, Das R, Choi SK, Wiederkehr A, Wollheim CB, Cha SK, Park KS.

Am J Physiol Endocrinol Metab. 2015 Jun 1;308(11):E933-41. doi: 10.1152/ajpendo.00009.2015. Epub 2015 Apr 7.

34.

Beta cell glutamate receptor antagonists: novel oral antidiabetic drugs?

Wollheim CB, Maechler P.

Nat Med. 2015 Apr;21(4):310-1. doi: 10.1038/nm.3835. No abstract available.

PMID:
25849270
35.

Nutrition and dietary intake and their association with mortality and hospitalisation in adults with chronic kidney disease treated with haemodialysis: protocol for DIET-HD, a prospective multinational cohort study.

Palmer SC, Ruospo M, Campbell KL, Garcia Larsen V, Saglimbene V, Natale P, Gargano L, Craig JC, Johnson DW, Tonelli M, Knight J, Bednarek-Skublewska A, Celia E, Del Castillo D, Dulawa J, Ecder T, Fabricius E, Frazão JM, Gelfman R, Hoischen SH, Schön S, Stroumza P, Timofte D, Török M, Hegbrant J, Wollheim C, Frantzen L, Strippoli GF; DIET-HD Study investigators.

BMJ Open. 2015 Mar 20;5(3):e006897. doi: 10.1136/bmjopen-2014-006897.

36.

Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion.

Stamenkovic JA, Andersson LE, Adriaenssens AE, Bagge A, Sharoyko VV, Gribble F, Reimann F, Wollheim CB, Mulder H, Spégel P.

Biochem J. 2015 May 15;468(1):49-63. doi: 10.1042/BJ20140697.

PMID:
25731850
37.

Essential role of mitochondrial Ca2+ uniporter in the generation of mitochondrial pH gradient and metabolism-secretion coupling in insulin-releasing cells.

Quan X, Nguyen TT, Choi SK, Xu S, Das R, Cha SK, Kim N, Han J, Wiederkehr A, Wollheim CB, Park KS.

J Biol Chem. 2015 Feb 13;290(7):4086-96. doi: 10.1074/jbc.M114.632547. Epub 2014 Dec 29.

38.

Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia.

Taneera J, Fadista J, Ahlqvist E, Atac D, Ottosson-Laakso E, Wollheim CB, Groop L.

Hum Mol Genet. 2015 Apr 1;24(7):1945-55. doi: 10.1093/hmg/ddu610. Epub 2014 Dec 8.

PMID:
25489054
39.

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.

Fadista J, Vikman P, Laakso EO, Mollet IG, Esguerra JL, Taneera J, Storm P, Osmark P, Ladenvall C, Prasad RB, Hansson KB, Finotello F, Uvebrant K, Ofori JK, Di Camillo B, Krus U, Cilio CM, Hansson O, Eliasson L, Rosengren AH, Renström E, Wollheim CB, Groop L.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13924-9. doi: 10.1073/pnas.1402665111. Epub 2014 Sep 8.

40.

TCF7L2 is a master regulator of insulin production and processing.

Zhou Y, Park SY, Su J, Bailey K, Ottosson-Laakso E, Shcherbina L, Oskolkov N, Zhang E, Thevenin T, Fadista J, Bennet H, Vikman P, Wierup N, Fex M, Rung J, Wollheim C, Nobrega M, Renström E, Groop L, Hansson O.

Hum Mol Genet. 2014 Dec 15;23(24):6419-31. doi: 10.1093/hmg/ddu359. Epub 2014 Jul 11.

41.

Patient satisfaction with in-centre haemodialysis care: an international survey.

Palmer SC, de Berardis G, Craig JC, Tong A, Tonelli M, Pellegrini F, Ruospo M, Hegbrant J, Wollheim C, Celia E, Gelfman R, Ferrari JN, Törok M, Murgo M, Leal M, Bednarek-Skublewska A, Dulawa J, Strippoli GF.

BMJ Open. 2014 May 19;4(5):e005020. doi: 10.1136/bmjopen-2014-005020.

42.

Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.

Dayeh T, Volkov P, Salö S, Hall E, Nilsson E, Olsson AH, Kirkpatrick CL, Wollheim CB, Eliasson L, Rönn T, Bacos K, Ling C.

PLoS Genet. 2014 Mar 6;10(3):e1004160. doi: 10.1371/journal.pgen.1004160. eCollection 2014 Mar.

43.

Mitochondrial phosphate transport during nutrient stimulation of INS-1E insulinoma cells.

Quan X, Das R, Xu S, Cline GW, Wiederkehr A, Wollheim CB, Park KS.

Mol Cell Endocrinol. 2013 Dec 5;381(1-2):198-209. doi: 10.1016/j.mce.2013.08.003. Epub 2013 Aug 9.

PMID:
23939247
44.

DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets.

Hall E, Dayeh T, Kirkpatrick CL, Wollheim CB, Dekker Nitert M, Ling C.

BMC Med Genet. 2013 Jul 23;14:76. doi: 10.1186/1471-2350-14-76.

45.

Oral disease in adults treated with hemodialysis: prevalence, predictors, and association with mortality and adverse cardiovascular events: the rationale and design of the ORAL Diseases in hemodialysis (ORAL-D) study, a prospective, multinational, longitudinal, observational, cohort study.

Strippoli GF, Palmer SC, Ruospo M, Natale P, Saglimbene V, Craig JC, Pellegrini F, Petruzzi M, De Benedittis M, Ford P, Johnson DW, Celia E, Gelfman R, Leal MR, Torok M, Stroumza P, Bednarek-Skublewska A, Dulawa J, Frantzen L, Ferrari JN, del Castillo D, Hegbrant J, Wollheim C, Gargano L; ORAL-D Investigators.

BMC Nephrol. 2013 Apr 19;14:90. doi: 10.1186/1471-2369-14-90.

46.

Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release.

Spégel P, Sharoyko VV, Goehring I, Danielsson AP, Malmgren S, Nagorny CL, Andersson LE, Koeck T, Sharp GW, Straub SG, Wollheim CB, Mulder H.

Biochem J. 2013 Mar 15;450(3):595-605. doi: 10.1042/BJ20121349.

PMID:
23282133
47.

Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction.

Bugliani M, Liechti R, Cheon H, Suleiman M, Marselli L, Kirkpatrick C, Filipponi F, Boggi U, Xenarios I, Syed F, Ladriere L, Wollheim C, Lee MS, Marchetti P.

Mol Cell Endocrinol. 2013 Mar 10;367(1-2):1-10. doi: 10.1016/j.mce.2012.12.001. Epub 2012 Dec 12.

PMID:
23246353
48.

Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.

Mahdi T, Hänzelmann S, Salehi A, Muhammed SJ, Reinbothe TM, Tang Y, Axelsson AS, Zhou Y, Jing X, Almgren P, Krus U, Taneera J, Blom AM, Lyssenko V, Esguerra JL, Hansson O, Eliasson L, Derry J, Zhang E, Wollheim CB, Groop L, Renström E, Rosengren AH.

Cell Metab. 2012 Nov 7;16(5):625-33. doi: 10.1016/j.cmet.2012.10.009.

49.

A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets.

Marchetti P, Lupi R, Bugliani M, Kirkpatrick CL, Sebastiani G, Grieco FA, Del Guerra S, D'Aleo V, Piro S, Marselli L, Boggi U, Filipponi F, Tinti L, Salvini L, Wollheim CB, Purrello F, Dotta F.

Diabetologia. 2012 Dec;55(12):3262-72. doi: 10.1007/s00125-012-2716-9. Epub 2012 Sep 11.

PMID:
22965295
50.

Pyruvate dehydrogenase E1α phosphorylation is induced by glucose but does not control metabolism-secretion coupling in INS-1E clonal β-cells.

Akhmedov D, De Marchi U, Wollheim CB, Wiederkehr A.

Biochim Biophys Acta. 2012 Oct;1823(10):1815-24. doi: 10.1016/j.bbamcr.2012.07.005. Epub 2012 Jul 15.

Supplemental Content

Loading ...
Support Center