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Items: 1 to 50 of 140


Single-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver.

Brazhnik K, Sun S, Alani O, Kinkhabwala M, Wolkoff AW, Maslov AY, Dong X, Vijg J.

Sci Adv. 2020 Jan 31;6(5):eaax2659. doi: 10.1126/sciadv.aax2659. eCollection 2020 Jan.


Prolonged Serum Alanine Aminotransferase Elevation Associated with Isotretinoin Administration.

Nazarian RS, Zheng E, Halverstam C, Cohen SR, Wolkoff AW.

Case Reports Hepatol. 2019 Jul 17;2019:9270827. doi: 10.1155/2019/9270827. eCollection 2019.


Faecal microbiota transplantation for diarrhoea-predominant irritable bowel syndrome: a double-blind, randomised, placebo-controlled trial.

Aroniadis OC, Brandt LJ, Oneto C, Feuerstadt P, Sherman A, Wolkoff AW, Kassam Z, Sadovsky RG, Elliott RJ, Budree S, Kim M, Keller MJ.

Lancet Gastroenterol Hepatol. 2019 Sep;4(9):675-685. doi: 10.1016/S2468-1253(19)30198-0. Epub 2019 Jul 17.


Rat Organic Anion Transport Protein 1A1 Interacts Directly With Organic Anion Transport Protein 1A4 Facilitating Its Maturation and Trafficking to the Hepatocyte Plasma Membrane.

Wang P, Wang WJ, Choi-Nurvitadhi J, Lescaille Y, Murray JW, Wolkoff AW.

Hepatology. 2019 Dec;70(6):2156-2170. doi: 10.1002/hep.30772. Epub 2019 Jun 26.


Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging.

Bejarano E, Murray JW, Wang X, Pampliega O, Yin D, Patel B, Yuste A, Wolkoff AW, Cuervo AM.

Aging Cell. 2018 Aug;17(4):e12777. doi: 10.1111/acel.12777. Epub 2018 May 29.


Reduction of organelle motility by removal of potassium and other solutes.

Murray JW, Yin D, Wolkoff AW.

PLoS One. 2017 Sep 18;12(9):e0184898. doi: 10.1371/journal.pone.0184898. eCollection 2017.


Drug- and Drug Abuse-Associated Hyperbilirubinemia: Experience With Atazanavir.

Roy-Chowdhury J, Roy-Chowdhury N, Listowsky I, Wolkoff AW.

Clin Pharmacol Drug Dev. 2017 Mar;6(2):140-146. doi: 10.1002/cpdd.314.


Intrahepatic Cholestasis of Pregnancy: New Diagnostic Insights.

Chacko KR, Wolkoff AW.

Ann Hepatol. 2017 March-April;16(2):176-178. doi: 10.5604/16652681.1231594. No abstract available.


A pre-neoplastic epigenetic field defect in HCV-infected liver at transcription factor binding sites and polycomb targets.

Wijetunga NA, Pascual M, Tozour J, Delahaye F, Alani M, Adeyeye M, Wolkoff AW, Verma A, Greally JM.

Oncogene. 2017 Apr 6;36(14):2030-2044. doi: 10.1038/onc.2016.340. Epub 2016 Oct 10.


Genetic analysis of nonalcoholic fatty liver disease within a Caribbean-Hispanic population.

Edelman D, Kalia H, Delio M, Alani M, Krishnamurthy K, Abd M, Auton A, Wang T, Wolkoff AW, Morrow BE.

Mol Genet Genomic Med. 2015 Aug 11;3(6):558-69. doi: 10.1002/mgg3.168. eCollection 2015 Nov.


The Na(+)-Taurocholate Cotransporting Polypeptide Traffics with the Epidermal Growth Factor Receptor.

Wang X, Wang P, Wang W, Murray JW, Wolkoff AW.

Traffic. 2016 Mar;17(3):230-44. doi: 10.1111/tra.12354. Epub 2016 Jan 10.


Hepatocytes maintain greater fluorescent bile acid accumulation and greater sensitivity to drug-induced cell death in three-dimensional matrix culture.

Murray JW, Han D, Wolkoff AW.

Physiol Rep. 2014 Dec 18;2(12). pii: e12198. doi: 10.14814/phy2.12198. Print 2014 Dec 1.


Organic anion uptake by hepatocytes.

Wolkoff AW.

Compr Physiol. 2014 Oct;4(4):1715-35. doi: 10.1002/cphy.c140023. Review.


Human liver cell trafficking mutants: characterization and whole exome sequencing.

Yuan F, Snapp EL, Novikoff PM, Suadicani SO, Spray DC, Potvin B, Wolkoff AW, Stanley P.

PLoS One. 2014 Jan 23;9(1):e87043. doi: 10.1371/journal.pone.0087043. eCollection 2014.


Rab1a regulates sorting of early endocytic vesicles.

Mukhopadhyay A, Quiroz JA, Wolkoff AW.

Am J Physiol Gastrointest Liver Physiol. 2014 Mar 1;306(5):G412-24. doi: 10.1152/ajpgi.00118.2013. Epub 2014 Jan 9.


Oatp1a1 requires PDZK1 to traffic to the plasma membrane by selective recruitment of microtubule-based motor proteins.

Wang WJ, Murray JW, Wolkoff AW.

Drug Metab Dispos. 2014 Jan;42(1):62-9. doi: 10.1124/dmd.113.054536. Epub 2013 Oct 10.


In vitro motility of liver connexin vesicles along microtubules utilizes kinesin motors.

Fort AG, Murray JW, Dandachi N, Davidson MW, Dermietzel R, Wolkoff AW, Spray DC.

J Biol Chem. 2011 Jul 1;286(26):22875-85. doi: 10.1074/jbc.M111.219709. Epub 2011 May 2.


Heterogeneous accumulation of fluorescent bile acids in primary rat hepatocytes does not correlate with their homogenous expression of ntcp.

Murray JW, Thosani AJ, Wang P, Wolkoff AW.

Am J Physiol Gastrointest Liver Physiol. 2011 Jul;301(1):G60-8. doi: 10.1152/ajpgi.00035.2011. Epub 2011 Apr 7.


Proteomic analysis of endocytic vesicles: Rab1a regulates motility of early endocytic vesicles.

Mukhopadhyay A, Nieves E, Che FY, Wang J, Jin L, Murray JW, Gordon K, Angeletti RH, Wolkoff AW.

J Cell Sci. 2011 Mar 1;124(Pt 5):765-75. doi: 10.1242/jcs.079020. Epub 2011 Feb 8.


PDZK1 binding and serine phosphorylation regulate subcellular trafficking of organic anion transport protein 1a1.

Choi JH, Murray JW, Wolkoff AW.

Am J Physiol Gastrointest Liver Physiol. 2011 Mar;300(3):G384-93. doi: 10.1152/ajpgi.00500.2010. Epub 2010 Dec 23.


Effectiveness of hepatitis C treatment with pegylated interferon and ribavirin in urban minority patients.

Feuerstadt P, Bunim AL, Garcia H, Karlitz JJ, Massoumi H, Thosani AJ, Pellecchia A, Wolkoff AW, Gaglio PJ, Reinus JF.

Hepatology. 2010 Apr;51(4):1137-43. doi: 10.1002/hep.23429.


A stimulus needed for the study of membrane traffic in hepatocytes.

McNiven MA, Wolkoff AW, Hubbard A.

Hepatology. 2009 Aug;50(2):345-8. doi: 10.1002/hep.23004. Review. No abstract available.


Rab4 facilitates cyclic adenosine monophosphate-stimulated bile acid uptake and Na+-taurocholate cotransporting polypeptide translocation.

Schonhoff CM, Thankey K, Webster CR, Wakabayashi Y, Wolkoff AW, Anwer MS.

Hepatology. 2008 Nov;48(5):1665-70. doi: 10.1002/hep.22495.


Topological assessment of oatp1a1: a 12-transmembrane domain integral membrane protein with three N-linked carbohydrate chains.

Wang P, Hata S, Xiao Y, Murray JW, Wolkoff AW.

Am J Physiol Gastrointest Liver Physiol. 2008 Apr;294(4):G1052-9. doi: 10.1152/ajpgi.00584.2007. Epub 2008 Feb 28.


Single vesicle analysis of endocytic fission on microtubules in vitro.

Murray JW, Sarkar S, Wolkoff AW.

Traffic. 2008 May;9(5):833-847. doi: 10.1111/j.1600-0854.2008.00725.x. Epub 2008 Feb 15.


In vitro motility system to study the role of motor proteins in receptor-ligand sorting.

Murray JW, Wolkoff AW.

Methods Mol Biol. 2007;392:143-58.


New liver cell mutants defective in the endocytic pathway.

Stockert RJ, Potvin B, Nath S, Wolkoff AW, Stanley P.

Biochim Biophys Acta. 2007 Jul;1768(7):1741-9. Epub 2007 Apr 14.


Kif5B and Kifc1 interact and are required for motility and fission of early endocytic vesicles in mouse liver.

Nath S, Bananis E, Sarkar S, Stockert RJ, Sperry AO, Murray JW, Wolkoff AW.

Mol Biol Cell. 2007 May;18(5):1839-49. Epub 2007 Mar 14.


Cellular and molecular biology of the liver.

Stockert RJ, Wolkoff AW.

Curr Opin Gastroenterol. 2001 May;17(3):205-10.


PKCzeta is required for microtubule-based motility of vesicles containing the ntcp transporter.

Sarkar S, Bananis E, Nath S, Anwer MS, Wolkoff AW, Murray JW.

Traffic. 2006 Aug;7(8):1078-91. Epub 2006 May 25.


Reconstitution of herpes simplex virus microtubule-dependent trafficking in vitro.

Lee GE, Murray JW, Wolkoff AW, Wilson DW.

J Virol. 2006 May;80(9):4264-75.


Rat organic anion transporting protein 1A1 (Oatp1a1): purification and phosphopeptide assignment.

Xiao Y, Nieves E, Angeletti RH, Orr GA, Wolkoff AW.

Biochemistry. 2006 Mar 14;45(10):3357-69.


Assay of Rab4-dependent trafficking on microtubules.

Murray JW, Wolkoff AW.

Methods Enzymol. 2005;403:92-107.


Adaptor heat shock protein complex formation regulates trafficking of the asialoglycoprotein receptor.

Huang T, Wolkoff AW, Stockert RJ.

Am J Physiol Gastrointest Liver Physiol. 2006 Feb;290(2):G369-76. Epub 2005 Oct 6.


Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators.

Wang X, Wolkoff AW, Morris ME.

Drug Metab Dispos. 2005 Nov;33(11):1666-72. Epub 2005 Aug 4.


Vascular binding, blood flow, transporter, and enzyme interactions on the processing of digoxin in rat liver.

Liu L, Mak E, Tirona RG, Tan E, Novikoff PM, Wang P, Wolkoff AW, Pang KS.

J Pharmacol Exp Ther. 2005 Oct;315(1):433-48. Epub 2005 Jun 30.


Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface.

Wang P, Wang JJ, Xiao Y, Murray JW, Novikoff PM, Angeletti RH, Orr GA, Lan D, Silver DL, Wolkoff AW.

J Biol Chem. 2005 Aug 26;280(34):30143-9. Epub 2005 Jun 30.


Microtubule-dependent movement of late endocytic vesicles in vitro: requirements for Dynein and Kinesin.

Bananis E, Nath S, Gordon K, Satir P, Stockert RJ, Murray JW, Wolkoff AW.

Mol Biol Cell. 2004 Aug;15(8):3688-97. Epub 2004 Jun 4.


Roles of the cytoskeleton and motor proteins in endocytic sorting.

Murray JW, Wolkoff AW.

Adv Drug Deliv Rev. 2003 Nov 14;55(11):1385-403. Review.


Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake.

Hata S, Wang P, Eftychiou N, Ananthanarayanan M, Batta A, Salen G, Pang KS, Wolkoff AW.

Am J Physiol Gastrointest Liver Physiol. 2003 Nov;285(5):G829-39. Epub 2003 Jul 3.


Regulation of early endocytic vesicle motility and fission in a reconstituted system.

Bananis E, Murray JW, Stockert RJ, Satir P, Wolkoff AW.

J Cell Sci. 2003 Jul 1;116(Pt 13):2749-61. Epub 2003 May 20.


The human organic anion transport protein SLC21A6 is not sufficient for bilirubin transport.

Wang P, Kim RB, Chowdhury JR, Wolkoff AW.

J Biol Chem. 2003 Jun 6;278(23):20695-9. Epub 2003 Mar 31.


Bile acid regulation of hepatic physiology: I. Hepatocyte transport of bile acids.

Wolkoff AW, Cohen DE.

Am J Physiol Gastrointest Liver Physiol. 2003 Feb;284(2):G175-9. Review.


Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation.

Tirona RG, Leake BF, Wolkoff AW, Kim RB.

J Pharmacol Exp Ther. 2003 Jan;304(1):223-8.


Phosphorylation-dependent interaction of the asialoglycoprotein receptor with molecular chaperones.

Huang T, Deng H, Wolkoff AW, Stockert RJ.

J Biol Chem. 2002 Oct 4;277(40):37798-803. Epub 2002 Aug 7.


Translated Alu sequence determines nuclear localization of a novel catalytic subunit of casein kinase 2.

Hilgard P, Huang T, Wolkoff AW, Stockert RJ.

Am J Physiol Cell Physiol. 2002 Aug;283(2):C472-83.


Immunofluorescence microchamber technique for characterizing isolated organelles.

Murray JW, Bananis E, Wolkoff AW.

Anal Biochem. 2002 Jun 1;305(1):55-67.


Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2.

Meng LJ, Wang P, Wolkoff AW, Kim RB, Tirona RG, Hofmann AF, Pang KS.

Hepatology. 2002 May;35(5):1031-40.


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