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Items: 1 to 50 of 176

1.

Yap/Taz regulate alveolar regeneration and resolution of lung inflammation.

LaCanna R, Liccardo D, Zhang P, Tragesser L, Wang Y, Cao T, Chapman HA, Morrisey EE, Shen H, Koch WJ, Kosmider B, Wolfson MR, Tian Y.

J Clin Invest. 2019 Apr 15;130:2107-2122. doi: 10.1172/JCI125014. eCollection 2019 Apr 15.

2.

Regenerative therapy based on miRNA-302 mimics for enhancing host recovery from pneumonia caused by Streptococcus pneumoniae.

Wang Y, Li Y, Zhang P, Baker ST, Wolfson MR, Weiser JN, Tian Y, Shen H.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8493-8498. doi: 10.1073/pnas.1818522116. Epub 2019 Apr 10.

PMID:
30971494
3.

Pulmonary mechanics measurements by respiratory inductive plethysmography and esophageal manometry: Methodology for infants on non-invasive respiratory support.

Sivieri EM, Wolfson MR, Abbasi S.

J Neonatal Perinatal Med. 2019 Jan 28. doi: 10.3233/NPM-1869. [Epub ahead of print]

PMID:
30714976
4.

Neuroprotective Effects of Nasopharyngeal Perfluorochemical Cooling in a Rat Model of Subarachnoid Hemorrhage.

Samanci MY, Calendo G, Baker ST, Erkmen K, Weaver MW, Wolfson MR.

World Neurosurg. 2019 Jan;121:e481-e492. doi: 10.1016/j.wneu.2018.09.142. Epub 2018 Sep 26.

PMID:
30267945
5.

Nebulization of Single-Chain Tissue-Type and Single-Chain Urokinase Plasminogen Activator for Treatment of Inhalational Smoke-Induced Acute Lung Injury.

Surasarang SH, Sahakijpijarn S, Florova G, Komissarov AA, Nelson CL, Perenlei E, Fukuda S, Wolfson MR, Shaffer TH, Idell S, Williams RO 3rd.

J Drug Deliv Sci Technol. 2018 Aug;48:19-27. doi: 10.1016/j.jddst.2018.04.013. Epub 2018 Apr 30.

PMID:
30123328
6.

Lack of durable protection against cotton smoke-induced acute lung injury in sheep by nebulized single chain urokinase plasminogen activator or tissue plasminogen activator.

Fukuda S, Enkhbaatar P, Nelson C, Cox RA, Wolfson MR, Shaffer TH, Williams RO 3rd, Surasarang SH, Sawittree S, Florova G, Komissarov AA, Koenig K, Sarva K, Ndetan HT, Singh KP, Idell S.

Clin Transl Med. 2018 Jun 18;7(1):17. doi: 10.1186/s40169-018-0196-3.

7.

A Feline HFpEF Model with Pulmonary Hypertension and Compromised Pulmonary Function.

Wallner M, Eaton DM, Berretta RM, Borghetti G, Wu J, Baker ST, Feldsott EA, Sharp TE 3rd, Mohsin S, Oyama MA, von Lewinski D, Post H, Wolfson MR, Houser SR.

Sci Rep. 2017 Nov 29;7(1):16587. doi: 10.1038/s41598-017-15851-2.

8.

Acute right heart failure after hemorrhagic shock and trauma pneumonectomy-a management approach: A blinded randomized controlled animal trial using inhaled nitric oxide.

Lubitz AL, Sjoholm LO, Goldberg A, Pathak A, Santora T, Sharp TE 3rd, Wallner M, Berretta RM, Poole LA, Wu J, Wolfson MR.

J Trauma Acute Care Surg. 2017 Feb;82(2):243-251. doi: 10.1097/TA.0000000000001325.

9.

A Novel Approach for Ovine Primary Alveolar Epithelial Type II Cell Isolation and Culture from Fresh and Cryopreserved Tissue Obtained from Premature and Juvenile Animals.

Marcinkiewicz MM, Baker ST, Wu J, Hubert TL, Wolfson MR.

PLoS One. 2016 Mar 21;11(3):e0152027. doi: 10.1371/journal.pone.0152027. eCollection 2016.

10.

Enhanced Re-Endothelialization of Decellularized Rat Lungs.

Stabler CT, Caires LC Jr, Mondrinos MJ, Marcinkiewicz C, Lazarovici P, Wolfson MR, Lelkes PI.

Tissue Eng Part C Methods. 2016 May;22(5):439-50. doi: 10.1089/ten.TEC.2016.0012. Epub 2016 Apr 1.

11.

The Effects of Lung Protective Ventilation or Hypercapnic Acidosis on Gas Exchange and Lung Injury in Surfactant Deficient Rabbits.

Hummler HD, Banke K, Wolfson MR, Buonocore G, Ebsen M, Bernhard W, Tsikas D, Fuchs H.

PLoS One. 2016 Feb 3;11(2):e0147807. doi: 10.1371/journal.pone.0147807. eCollection 2016.

12.

High flow nasal heliox improves work of breathing and attenuates lung injury in a newborn porcine lung injury model.

Jassar RK, Vellanki H, Zhu Y, Hesek AM, Wang J, Rodriguez E, Wolfson MR, Shaffer TH.

J Neonatal Perinatal Med. 2015;8(4):323-31. doi: 10.3233/NPM-15915039.

PMID:
26757007
13.

Ex vivo ovine model for pediatric flexible endoscopy training.

Isaacson G, Ianacone DC, Wolfson MR.

Int J Pediatr Otorhinolaryngol. 2015 Dec;79(12):2196-9. doi: 10.1016/j.ijporl.2015.10.002. Epub 2015 Oct 23.

PMID:
26514929
14.

Biodistribution and Efficacy of Targeted Pulmonary Delivery of a Protein Kinase C-δ Inhibitory Peptide: Impact on Indirect Lung Injury.

Mondrinos MJ, Knight LC, Kennedy PA, Wu J, Kauffman M, Baker ST, Wolfson MR, Kilpatrick LE.

J Pharmacol Exp Ther. 2015 Oct;355(1):86-98. doi: 10.1124/jpet.115.224832. Epub 2015 Aug 4.

15.

The orl rat is more responsive to methacholine challenge than wild type.

Rodriguez E, Barthold JS, Kreiger PA, Armani MH, Wang J, Michelini KA, Wolfson MR, Boyce R, Barone CA, Zhu Y, Waldman SA, Shaffer TH.

Pulm Pharmacol Ther. 2014 Dec;29(2):199-208. doi: 10.1016/j.pupt.2014.09.001. Epub 2014 Sep 16.

16.

High flow nasal cannula (HFNC) with Heliox decreases diaphragmatic injury in a newborn porcine lung injury model.

Jassar RK, Vellanki H, Zhu Y, Hesek A, Wang J, Rodriguez E, Wu J, Shaffer TH, Wolfson MR.

Pediatr Pulmonol. 2014 Dec;49(12):1214-22. doi: 10.1002/ppul.23000. Epub 2014 Feb 5.

17.

Pulmonary endothelial protein kinase C-delta (PKCδ) regulates neutrophil migration in acute lung inflammation.

Mondrinos MJ, Zhang T, Sun S, Kennedy PA, King DJ, Wolfson MR, Knight LC, Scalia R, Kilpatrick LE.

Am J Pathol. 2014 Jan;184(1):200-13. doi: 10.1016/j.ajpath.2013.09.010. Epub 2013 Nov 6.

18.

Aerosolized KL4 surfactant improves short-term survival and gas exchange in spontaneously breathing newborn pigs with hydrochloric acid-induced acute lung injury.

Lampland AL, Wolfson MR, Mazela J, Henderson C, Gregory TJ, Meyers P, Plumm B, Worwa C, Mammel MC.

Pediatr Pulmonol. 2014 May;49(5):482-9. doi: 10.1002/ppul.22844. Epub 2013 Sep 3.

PMID:
24039229
19.

Lucinactant attenuates pulmonary inflammatory response, preserves lung structure, and improves physiologic outcomes in a preterm lamb model of RDS.

Wolfson MR, Wu J, Hubert TL, Gregory TJ, Mazela J, Shaffer TH.

Pediatr Res. 2012 Oct;72(4):375-83. doi: 10.1038/pr.2012.96. Epub 2012 Jul 20.

20.

Neonatal non-invasive respiratory support: physiological implications.

Shaffer TH, Alapati D, Greenspan JS, Wolfson MR.

Pediatr Pulmonol. 2012 Sep;47(9):837-47. doi: 10.1002/ppul.22610. Epub 2012 Jul 6. Review.

21.

Translational research: matching experimental models with therapeutic interventions.

Shaffer TH, Wolfson MR.

Pediatr Crit Care Med. 2012 May;13(3):369-70. doi: 10.1097/PCC.0b013e31823c9a51. No abstract available.

PMID:
22561272
22.

Hyperoxia during one lung ventilation: inflammatory and oxidative responses.

Olivant Fisher A, Husain K, Wolfson MR, Hubert TL, Rodriguez E, Shaffer TH, Theroux MC.

Pediatr Pulmonol. 2012 Oct;47(10):979-86. doi: 10.1002/ppul.22517. Epub 2012 Mar 19.

23.

Brief mechanical ventilation impacts airway cartilage properties in neonatal lambs.

Kim M, Pugarelli J, Miller TL, Wolfson MR, Dodge GR, Shaffer TH.

Pediatr Pulmonol. 2012 Aug;47(8):763-70. doi: 10.1002/ppul.21616. Epub 2011 Dec 13.

24.

Perfluorochemical liquid-adenovirus suspensions enhance gene delivery to the distal lung.

Kazzaz JA, Strayer MS, Wu J, Malone DJ, Koo HC, Shaffer TH, Davis JM, Strayer DS, Wolfson MR.

Pulm Med. 2011;2011:918036. doi: 10.1155/2011/918036. Epub 2011 Aug 18.

25.

Pregnancy and outcome of uterine allotransplantation and assisted reproduction in sheep.

Ramirez ER, Ramirez Nessetti DK, Nessetti MB, Khatamee M, Wolfson MR, Shaffer TH, Ramirez VZ, Ramirez HA.

J Minim Invasive Gynecol. 2011 Mar-Apr;18(2):238-45. doi: 10.1016/j.jmig.2010.11.006.

PMID:
21354071
26.

Prototype hybrid systems for neonatal warming: in vitro comparisons to standard of care devices.

Hubert TL, Lindemann R, Wu J, Agnew C, Shaffer TH, Wolfson MR.

Biomed Instrum Technol. 2010 Nov-Dec;44(6):523-7. doi: 10.2345/0899-8205-44.6.523.

27.

Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-δ (δ-PKC).

Kilpatrick LE, Standage SW, Li H, Raj NR, Korchak HM, Wolfson MR, Deutschman CS.

J Leukoc Biol. 2011 Jan;89(1):3-10. doi: 10.1189/jlb.0510281. Epub 2010 Aug 19.

28.

Improved gas exchange and survival after KL-4 surfactant in newborn pigs with severe acute lung injury.

Zimmermann AM, Roberts KD, Lampland AL, Meyers PA, Worwa CT, Plumm B, Pacheco MC, Wolfson MR, Mammel MC.

Pediatr Pulmonol. 2010 Aug;45(8):782-8. doi: 10.1002/ppul.21252.

PMID:
20597076
29.

Research in high flow therapy: mechanisms of action.

Dysart K, Miller TL, Wolfson MR, Shaffer TH.

Respir Med. 2009 Oct;103(10):1400-5. doi: 10.1016/j.rmed.2009.04.007. Epub 2009 May 21. Review.

30.

Developmental differences in the contractile response of isolated ovine tracheal smooth muscle cells.

Laudadio RE, Wolfson MR, Shaffer TH, Driska SP.

Pediatr Pulmonol. 2009 Jun;44(6):602-12. doi: 10.1002/ppul.21042.

31.

Clinical design functions: round table discussions on the bioengineering of liquid ventilators.

Costantino ML, Micheau P, Shaffer TH, Tredici S, Wolfson MR; 6th Internationl Symposium on Perfluorocarbon Application and Liquid Ventilation.

ASAIO J. 2009 May-Jun;55(3):206-8. doi: 10.1097/MAT.0b013e318199c167. Review.

PMID:
19282746
32.

Recombinant human Clara cell secretory protein treatment increases lung mRNA expression of surfactant proteins and vascular endothelial growth factor in a premature lamb model of respiratory distress syndrome.

Wolfson MR, Funanage VL, Kirwin SM, Pilon AL, Shashikant BN, Miller TL, Shaffer TH.

Am J Perinatol. 2008 Nov;25(10):637-45. doi: 10.1055/s-0028-1090587. Epub 2008 Oct 7.

PMID:
18841530
33.

High vapor pressure perfluorocarbons cause vesicle fusion and changes in membrane packing.

Venegas B, Wolfson MR, Cooke PH, Chong PL.

Biophys J. 2008 Nov 15;95(10):4737-47. doi: 10.1529/biophysj.108.133496. Epub 2008 Aug 8.

34.

Multicenter comparative study of conventional mechanical gas ventilation to tidal liquid ventilation in oleic acid injured sheep.

Wolfson MR, Hirschl RB, Jackson JC, Gauvin F, Foley DS, Lamm WJ, Gaughan J, Shaffer TH.

ASAIO J. 2008 May-Jun;54(3):256-69. doi: 10.1097/MAT.0b013e318168fef0.

PMID:
18496275
35.

Intranasal perfluorochemical spray for preferential brain cooling in sheep.

Wolfson MR, Malone DJ, Wu J, Hoffman J, Rozenberg A, Shaffer TH, Barbut D.

Neurocrit Care. 2008;8(3):437-47. doi: 10.1007/s12028-008-9064-0.

PMID:
18266110
36.

Correlation of tracheal smooth muscle function with structure and protein expression during early development.

Cullen AB, Cooke PH, Driska SP, Wolfson MR, Shaffer TH.

Pediatr Pulmonol. 2007 May;42(5):421-32.

PMID:
17436327
37.

Effects of perfluorochemical evaporative properties on oxygenation during partial liquid ventilation.

Jeng MJ, Yang SS, Hwang B, Wolfson MR, Shaffer TH.

Pediatr Int. 2006 Dec;48(6):608-15.

PMID:
17168983
38.

Effects of recombinant Clara cell secretory protein (rhCC10) on inflammatory-related matrix metalloproteinase activity in a preterm lamb model of neonatal respiratory distress.

Miller TL, Shashikant BN, Pilon AL, Pierce RA, Shaffer TH, Wolfson MR.

Pediatr Crit Care Med. 2007 Jan;8(1):40-6.

PMID:
17149150
39.

Perfluorochemical liquids enhance delivery of superoxide dismutase to the lungs of juvenile rabbits.

Brunelli L, Hamilton E, Davis JM, Koo HC, Joseph A, Kazzaz JA, Wolfson MR, Shaffer TH.

Pediatr Res. 2006 Jul;60(1):65-70. Epub 2006 May 11.

PMID:
16690961
40.

A prototype infant incubator for heliox therapy.

Singhaus CJ, Touch SM, Greenspan JS, Wolfson MR, Shaffer TH.

Biomed Instrum Technol. 2006 Mar-Apr;40(2):150-63.

PMID:
16649483
41.

The impact of mechanical ventilation on immature airway smooth muscle: functional, structural, histological, and molecular correlates.

Cullen AB, Cooke PH, Driska SP, Wolfson MR, Shaffer TH.

Biol Neonate. 2006;90(1):17-27. Epub 2006 Mar 7.

PMID:
16534184
42.

Recombinant human Clara cell secretory protein in acute lung injury of the rabbit: effect of route of administration.

Miller TL, Shashikant BN, Melby JM, Pilon AL, Shaffer TH, Wolfson MR.

Pediatr Crit Care Med. 2005 Nov;6(6):698-706.

PMID:
16276338
43.

Effects of an intratracheally delivered anti-inflammatory protein (rhCC10) on physiological and lung structural indices in a juvenile model of acute lung injury.

Miller TL, Shashikant BN, Pilon AL, Pierce RA, Shaffer TH, Wolfson MR.

Biol Neonate. 2006;89(3):159-70. Epub 2005 Oct 6.

PMID:
16210850
44.

Heliox attenuates lung inflammation and structural alterations in acute lung injury.

Nawab US, Touch SM, Irwin-Sherman T, Blackson TJ, Greenspan JS, Zhu G, Shaffer TH, Wolfson MR.

Pediatr Pulmonol. 2005 Dec;40(6):524-32.

PMID:
16193495
45.

Dose response to rhCC10-augmented surfactant therapy in a lamb model of infant respiratory distress syndrome: physiological, inflammatory, and kinetic profiles.

Shashikant BN, Miller TL, Welch RW, Pilon AL, Shaffer TH, Wolfson MR.

J Appl Physiol (1985). 2005 Dec;99(6):2204-11. Epub 2005 Aug 4.

46.

Pulmonary applications of perfluorochemical liquids: ventilation and beyond.

Wolfson MR, Shaffer TH.

Paediatr Respir Rev. 2005 Jun;6(2):117-27. Review.

PMID:
15911457
47.

Differential impact of perfluorochemical physical properties on the physiologic, histologic, and inflammatory profile in acute lung injury.

Shashikant BN, Miller TL, Jeng MJ, Davis J, Shaffer TH, Wolfson MR.

Crit Care Med. 2005 May;33(5):1096-103.

PMID:
15891342
48.

Neonatal chest wall suspension splint: a novel and noninvasive method for support of lung volume.

Miller TL, Palmer C, Shaffer TH, Wolfson MR.

Pediatr Pulmonol. 2005 Jun;39(6):512-20.

PMID:
15678504
49.

Tracheal gas insufflation as a lung-protective strategy: physiologic, histologic, and biochemical markers.

Oliver RE, Rozycki HJ, Greenspan JS, Wolfson MR, Shaffer TH.

Pediatr Crit Care Med. 2005 Jan;6(1):64-9.

PMID:
15636662
50.

Cold perfluorochemical-induced hypothermia protects lung integrity in normal rabbits.

Yang SS, Jeng MJ, McShane R, Chen CY, Wolfson MR, Shaffer TH.

Biol Neonate. 2005;87(1):60-5. Epub 2004 Sep 30.

PMID:
15467294

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